Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 10, 2003, Pages 5736-5741

  Armstrong, Neali ^a   Mayer, Mark ^b   Gouaux, Eric ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; GLUTAMATE RECEPTOR; ION CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; GENE REARRANGEMENT; GENETIC CONSERVATION; GENETIC REGULATION; LIGAND BINDING; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; RECEPTOR BINDING; X RAY CRYSTALLOGRAPHY;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; AMINO ACID SUBSTITUTION; ANIMALS; CRYSTALLOGRAPHY, X-RAY; EXCITATORY AMINO ACID AGONISTS; FEMALE; KAINIC ACID; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OVARY; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, AMPA; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

ANIMALIA;

EID: 0038625032     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1037393100     Document Type: Article

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