Model systems in drug discovery: Chemical genetics meets genomics

Pharmacology and Therapeutics

Volumn 99, Issue 2, 2003, Pages 183-220

  Carroll, Pamela M ^a   Dougherty, Brian ^a   Ross Macdonald, Petra ^a   Browman, Kailtin ^a,b   FitzGerald, Kevin ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Caenorhabditis elegans; Drosophila; Drug discovery; Genetics; Genomics; Mechanism of action; Microarray; Mouse; RNA interference; Yeast

Indexed keywords

ALZHEIMER DISEASE; BACTERIAL GENETICS; BACTERIUM; BIOINFORMATICS; CAENORHABDITIS ELEGANS; CELL DEATH; CHEMICAL ANALYSIS; CHEMICAL GENETICS; DNA MICROARRAY; DROSOPHILA; DRUG INDUSTRY; DRUG RESEARCH; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE MAPPING; GENE SEQUENCE; GENETIC SCREENING; GENOME; GENOMICS; MASS SPECTROMETRY; MOLECULAR CLONING; MUTAGENESIS; MUTANT; NEMATODE; NONHUMAN; ONCOGENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEOMICS; REVIEW; TOXICOLOGY; TRANSPOSON; YEAST;

EID: 0041344669     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(03)00059-7     Document Type: Review

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