Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries

Chemistry and Biology

Volumn 7, Issue 1, 2000, Pages 17-25

  Hyde Deruyscher, R ^a   Paige, L A ^a   Christensen, D J ^a   Hyde Deruyscher, N ^a   Lim, A ^b   Fredericks, Z L ^b   Kranz, J ^b   Gallant, P ^b   Zhang, J ^b   Rocklage, S M ^b   Fowlkes, D M ^a   Wendler, P A ^b   Hamilton, P T ^a  

^a Novalon Pharmaceutical Corporation   (United States)

^b CUBIST PHARMACEUTICALS INC   (United States)

Author keywords

Enzyme inhibitors; Fluorescence polarization; High throughput screening; Peptide ligand; Phage display; Time resolved fluorescence

Indexed keywords

AMINO ACID SEQUENCE; BINDING ASSAY; BINDING SITE; COMBINATORIAL LIBRARY; ENZYME BINDING; ENZYME INHIBITOR; HAEMOPHILUS INFLUENZAE; LIGAND; PEPTIDE LIBRARY; PHAGE DISPLAY; PROTEIN DETECTION;

HAEMOPHILUS INFLUENZAE;

EID: 0034092470     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(00)00062-4     Document Type: Article

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