The roles of signaling by the p42/p44 mitogen-activated protein (MAP) kinase pathway; A potential route to radio- and chemo-sensitization of tumor cells resulting in the induction of apoptosis and loss of clonogenicity

Leukemia

Volumn 12, Issue 12, 1998, Pages 1843-1850

  Dent, P ^a   Jarvis, W D ^a   Birrer, M J ^b   Fisher, P B ^c   Schmidt Ullrich, R K ^a   Grant, S ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c Department of Pathology and Urology ^*  (United States)

Author keywords

Apoptosis; Cyclin kinase inhibitor protein; Differentiation; Growth factor; MAP kinase; Proliferation; SAP kinase

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN P21;

APOPTOSIS; CHEMOSENSITIVITY; CLONOGENESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; RADIOSENSITIVITY; REVIEW; SIGNAL TRANSDUCTION; TUMOR CELL;

EID: 0031759748     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401222     Document Type: Review

References (7)

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