Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci

Journal of Bacteriology

Volumn 183, Issue 24, 2001, Pages 7341-7353

  Dunman, P M ^a   Murphy, E ^a   Haney, S ^a   Palacios, D ^a   Tucker Kellogg, G ^a   Wu, S ^a   Brown, E L ^a   Zagursky, R J ^a   Shlaes, D ^a   Projan, S J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOXIN; BACTERIAL RNA; HEMOLYSIN; OLIGONUCLEOTIDE; PROTEIN A; PROTEIN AGR; REGULATOR PROTEIN; SMAD ANCHOR FOR RECEPTOR ACTIVATION; UNCLASSIFIED DRUG;

BACTERIAL GROWTH; BACTERIAL MUTATION; BACTERIAL VIRULENCE; CONFERENCE PAPER; CONTROLLED STUDY; DNA MICROARRAY; GENE CONTROL; GENE LOCUS; GENETIC TRANSCRIPTION; GENOME; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; BACTERIAL TOXINS; DNA-BINDING PROTEINS; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; HEMOLYSIN PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OPEN READING FRAMES; STAPHYLOCOCCAL PROTEIN A; STAPHYLOCOCCUS AUREUS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; UP-REGULATION; VIRULENCE;

EID: 0035212002     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.24.7341-7353.2001     Document Type: Conference Paper

References (35)

1. Regulation of Staphylococcus aureus pathogenesis via target of RNAIII-activating protein (TRAP)
2. The molecular architecture of the sar locus in Staphylococcus aureus
3. Epidemiology and prevention of nosocomial infections
4. Role of the arginine deiminase system in protecting oral bacteria and an enzymatic basis for acid tolerance
5. The role of environmental factors in the regulation of virulence-determinant expression in Staphylococcus aureus 8325-4
6. Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus
7. sar genetic determinants necessary for transcription of RNAII and RNAIII in the agr locus of Staphylococcus aureus
8. Regulation of protein A synthesis by the sar and agr loci of Staphylococcus aureus
9. Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr
10. Cloning and sequencing of sarA of Staphylococcus aureus, a gene required for the expression of agr
11. SarS, a SarA homolog repressible by agr, is an activator of protein A synthesis in Staphylococcus aureus
12. SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation
13. Molecular interactions between two global regulators, sar and agr, in Staphylococcus aureus
14. Role of CodY in regulation of the Bacillus subtilis hut operon
15. Characterization of the sar locus and its interaction with agr in Staphylococcus aureus
16. Identification and nucleotide sequence of the delta-lysin gene, hld, adjacent to the accessory gene regulator (agr) of Staphylococcus aureus
17. Bacterial interference caused by autoinducing peptide variants
18. Cell density control of staphylococcal virulence mediated by an octapeptide pheromone
19. Whole genome sequencing of methicillin-resistant Staphylococcus aureus
20. Interactive regulatory pathways control virulence determinant production and stability in response to environmental conditions in Staphylococcus aureus
21. Expression monitoring by hybridization to high-density oligonucleotide arrays
22. GeneMark.hmm: New solutions for gene finding
23. The arcABDC gene cluster, encoding the arginine deiminase pathway of Bacillus licheniformis, and its activation by the arginine repressor argR
24. The role of cytokines in bacterial pneumonia: An inflammatory balancing act
25. Pathogenicity factors and their regulation
26. The agr P2 operon: An autocatalytic sensory transduction system in Staphylococcus aureus
27. Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule
28. The molecular basis of pathogenicity
29. Regulation of exoprotein gene expression in Staphylococcus aureus by agr
30. Molecular characterization of a novel Staphylococcus aureus serine protease operon
31. Microbial gene identification using interpolated Markov models
32. Identification and characterization of SarH1, a new global regulator of virulence gene expression in Staphylococcus aureus
33. A temporal signal, independent of agr, is required for hla but not spa transcription in Staphylococcus aureus
34. Agr-independent regulation of fibronectinbinding protein(s) by the regulatory locus sar in Staphylococcus aureus