-
1
-
-
0034677966
-
Drug discovery: a historical perspective
-
(2000)
Science
, vol.287
, pp. 1960-1964
-
-
Drews, J.1
-
4
-
-
0029584327
-
KSR, a novel protein kinase required for Ras signal transduction
-
(1995)
Cell
, vol.83
, pp. 879-888
-
-
Therrien, M.1
-
5
-
-
0029559183
-
The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction
-
(1995)
Cell
, vol.83
, pp. 889-901
-
-
Sundaram, M.1
Han, M.2
-
6
-
-
0029588204
-
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
-
(1995)
Cell
, vol.83
, pp. 903-913
-
-
Kornfeld, K.1
-
9
-
-
0032568248
-
Resistance and cross-resistance with saquinavir and other HIV protease inhibitors: theory and practice
-
(1998)
AIDS
, vol.12
, pp. 453-460
-
-
Roberts, N.A.1
-
11
-
-
0029901502
-
A single point mutant in CTP synthetase of Chlamydia trachomatis confers resistance to cyclopentenyl cytosine
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15393-15400
-
-
Wylie, J.L.1
-
12
-
-
0033931237
-
Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug binding site
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 2100-2108
-
-
Korsinczky, M.1
-
14
-
-
0034708444
-
Comparative genomics of the eukaryotes
-
(2000)
Science
, vol.287
, pp. 2204-2215
-
-
Rubin, G.M.1
-
15
-
-
0002955384
-
Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain
-
(1999)
Mol. Cell
, vol.3
, pp. 275-285
-
-
Peyroche, A.1
-
18
-
-
0034237675
-
Strategies for discovering drugs from previously unexplored natural products
-
(2000)
Drug Discov. Today
, vol.5
, pp. 294-300
-
-
Harvey, A.1
-
21
-
-
8544273658
-
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI
-
(1997)
Nature
, vol.387
, Issue.SUPPL. 6632
, pp. 103-105
-
-
Bussey, H.1
-
22
-
-
0030831182
-
Genetic and physical maps of Saccharomyces cerevisiae
-
(1997)
Nature
, vol.387
, Issue.SUPPL. 6632
, pp. 67-73
-
-
Cherry, J.M.1
-
25
-
-
0023779728
-
Structural and functional conservation between yeast and human 3-hydroxy-3-methylglutaryl coenzyme A reductases, the rate-limiting enzyme of sterol biosynthesis
-
(1988)
Mol. Cell Biol.
, vol.8
, pp. 3797-3808
-
-
Basson, M.E.1
-
26
-
-
0032895836
-
Comprehensive evaluation of isoprenoid biosynthesis regulation in Saccharomyces cerevisiae utilizing the genome reporter matrix
-
(1999)
J. Lipid Res.
, vol.40
, pp. 850-860
-
-
Dimster-Denk, D.1
-
27
-
-
0034616930
-
Functional discovery via a compendium of expression profiles
-
(2000)
Cell
, vol.102
, pp. 109-126
-
-
Hughes, T.R.1
-
32
-
-
0028835184
-
Genetic pharmacological analysis of neurotransmitters controlling egg laying in C. elegans
-
(1995)
J. Neurosci.
, vol.15
, pp. 6975-6985
-
-
Weinshenker, D.1
-
33
-
-
0033198830
-
Serotonin inhibition of synaptic transmission: Gα(0) decreases the abundance of UNC-13 at release sites
-
(1999)
Neuron
, vol.24
, pp. 231-242
-
-
Nurrish, S.1
-
34
-
-
0032518346
-
Stereotypic behavioural responses to free-base cocaine and the development of behavioral sensitization in Drosophila
-
(1998)
Curr. Biol.
, vol.8
, pp. 109-112
-
-
McClung, C.1
Hirsh, J.2
-
35
-
-
0034708147
-
Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster
-
(2000)
Curr. Biol.
, vol.10
, pp. 211-214
-
-
Li, H.1
-
37
-
-
0033551867
-
Circadian genes are required for cocaine sensitization in Drosophila
-
(1999)
Science
, vol.285
, pp. 1066-1068
-
-
Andretic, R.1
-
38
-
-
0032511188
-
Ethanol intoxication in Drosophila: genetic and pharmacological evidence for regulation by the cAMP signaling pathway
-
(1998)
Cell
, vol.93
, pp. 997-1007
-
-
Moore, M.S.1
-
39
-
-
0033117634
-
The identification of myriocin-binding proteins
-
(1999)
Chem. Biol.
, vol.6
, pp. 221-235
-
-
Chen, J.K.1
-
40
-
-
0028300782
-
GTP-dependent binding of the antiproliferative agent didemnin to elongation factor 1α
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15411-15414
-
-
Crews, C.M.1
-
42
-
-
0034681943
-
Inhibition of protein synthesis by didemnin B: how EF-1α mediates inhibition of translocation
-
(2000)
Biochemistry
, vol.39
, pp. 4339-4346
-
-
Ahuja, D.1
-
44
-
-
0032515029
-
Structure of human methionine aminopeptidase-2 complexed with fumagillin
-
(1998)
Science
, vol.282
, pp. 1324-1327
-
-
Liu, S.1
-
45
-
-
0033517802
-
Inhibition of angiogenesis in vivo by ets-1 antisense oligonucleotides - Inhibition of Ets-1 transcription factor expression by the antibiotic fumagillin, Angew. Chem
-
(1999)
Int. Ed. Engl.
, vol.38
, pp. 3228-3231
-
-
Wernert, N.1
-
46
-
-
53249145476
-
Peptide sequencing by mass spectrometry for homology searches and cloning of genes
-
(1997)
J. Prot. Chem.
, vol.16
, pp. 481-490
-
-
Shevchenko, A.1
-
48
-
-
0002867860
-
Strategy and tactics in receptor-binding studies
-
Hulme E.C. (Ed.), Receptor-ligand Interactions: A Practical Approach, Oxford University Press
-
(1992)
, pp. 63-176
-
-
Hulme, E.C.1
Birdsall, N.J.M.2
-
50
-
-
0034616912
-
Biomedical discovery with DNA arrays
-
(2000)
Cell
, vol.102
, pp. 9-15
-
-
Young, R.A.1
-
51
-
-
0032818131
-
Gene expression analysis by transcript profiling coupled to a gene database query
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 798-803
-
-
Shimkets, R.A.1
-
53
-
-
0028040134
-
Identification of the yeast ACC1 gene product (acetyl-CoA carboxylase) as the target of the polyketide fungicide soraphen A
-
(1994)
Curr. Genet.
, vol.25
, pp. 95-100
-
-
Vahlensieck, H.F.1
-
54
-
-
0028036881
-
Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans
-
(1994)
Nature
, vol.371
, pp. 707-711
-
-
Cully, D.F.1
|