Positionally cloned human disease genes: Patterns of evolutionary conservation and functional motifs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 11, 1997, Pages 5831-5836

  Mushegian, Arcady R ^a   Bassett Jr , Douglas E ^a,b   Boguski, Mark S ^a   Bork, Peer ^c,d   Koonin, Eugene V ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COLON CANCER; EVOLUTION; GENE ISOLATION; GENETIC CONSERVATION; HUMAN; MOLECULAR CLONING; PREDICTION; PRIORITY JOURNAL; WERNER SYNDROME;

AMINO ACID SEQUENCE; ANIMALS; BACTERIA; CLONING, MOLECULAR; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; CONSERVED SEQUENCE; DNA POLYMERASE I; DNA TOPOISOMERASES, TYPE II; EVOLUTION; GENETIC DISEASES, INBORN; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INFORMATION SYSTEMS; MOLECULAR SEQUENCE DATA; MUTATION; NEMATODA; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS);

EID: 0030915681     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.11.5831     Document Type: Article

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