메뉴 건너뛰기




Volumn 2, Issue 5, 1999, Pages 509-515

Novel antifungal drugs

Author keywords

[No Author keywords available]

Indexed keywords

2 (2,4 DIFLUOROPHENYL) 3 [4 [4 [2 (4 TRIFLUOROMETHOXYBENZYL) 2H 1,2,4 TRIAZOL 3 ONE 4 YL]PHENYL]PIPERAZIN 1 YL] 1 (1H 1,2,4 TRIAZOL 1 YL)BUTAN 2 OL; ALBACONAZOLE; AMPHOTERICIN B; AMPHOTERICIN B CHOLESTEROL SULFATE; AMPHOTERICIN B LIPID COMPLEX; ANIDULAFUNGIN; ANTIFUNGAL AGENT; FLUCONAZOLE; FLUCYTOSINE; ITRACONAZOLE; MICONAZOLE; NIKKOMYCIN; NYSTATIN; POLYENE ANTIBIOTIC AGENT; POSACONAZOLE; RAVUCONAZOLE; TERBINAFINE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; VORICONAZOLE;

EID: 0032832199     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(99)00009-0     Document Type: Review
Times cited : (76)

References (92)
  • 5
    • 0031197111 scopus 로고    scopus 로고
    • The search for new triazole antifungal agents
    • Koltin Y, Hitchcock CA The search for new triazole antifungal agents. Curr Opin Chem Biol. 1:1997;176-182.
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 176-182
    • Koltin, Y.1    Hitchcock, C.A.2
  • 6
    • 0032173607 scopus 로고    scopus 로고
    • Antifungals: Mechanism of action and resistance, established and novel drugs
    • An excellent review that discusses both the mode of action and resistance for a number of established and emerging antifungals
    • Georgopapapdakou NH Antifungals: mechanism of action and resistance, established and novel drugs. Curr Opin Microbiol. 1:1998;547-557. An excellent review that discusses both the mode of action and resistance for a number of established and emerging antifungals.
    • (1998) Curr Opin Microbiol , vol.1 , pp. 547-557
    • Georgopapapdakou, N.H.1
  • 10
    • 0031904301 scopus 로고    scopus 로고
    • AmBisome (Liposomal Amphotericin B): A comparative review
    • An interesting review of the liposomal formulations of amphotericin B and their efficacy
    • Boswell GW, Buell D, Bekersky I AmBisome (Liposomal Amphotericin B): a comparative review. J Clin Pharmacol. 38:1998;583-592. An interesting review of the liposomal formulations of amphotericin B and their efficacy.
    • (1998) J Clin Pharmacol , vol.38 , pp. 583-592
    • Boswell, G.W.1    Buell, D.2    Bekersky, I.3
  • 12
    • 0031805398 scopus 로고    scopus 로고
    • Comparison in in vitro antifungal activities of free and liposome-encapsulated nystatin with those of four amphotericin B formulations
    • Johnson EM, Ojwang JO, Szekely A, Wallace TL, Denning DW Comparison in in vitro antifungal activities of free and liposome-encapsulated nystatin with those of four amphotericin B formulations. Antimicrob Agents Chemother. 42:1998;1412-1416.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1412-1416
    • Johnson, E.M.1    Ojwang, J.O.2    Szekely, A.3    Wallace, T.L.4    Denning, D.W.5
  • 13
    • 0032911982 scopus 로고    scopus 로고
    • Comparison of in vitro ativity of liposomal nystatin (Nyotran) against Aspergillus species with those of nystatin, amphotericin B (AB) deoxycholate, AB colloidal dispersion, liposomal AB, AB lipid complex, and itraconazole
    • Oakley KL, Moore CB, Denning DW Comparison of in vitro ativity of liposomal nystatin (Nyotran) against Aspergillus species with those of nystatin, amphotericin B (AB) deoxycholate, AB colloidal dispersion, liposomal AB, AB lipid complex, and itraconazole. Antimicrob Agents Chemother. 43:1999;1246-1264.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1246-1264
    • Oakley, K.L.1    Moore, C.B.2    Denning, D.W.3
  • 15
    • 0031819776 scopus 로고    scopus 로고
    • In vitro activity of voriconazole against Aspergillus spp. and comparison with itraconazole and amphotericin B
    • Oakley KL, Moore CB, Denning DW In vitro activity of voriconazole against Aspergillus spp. and comparison with itraconazole and amphotericin B. J Antimicrob Chemother. 42:1998;91-94.
    • (1998) J Antimicrob Chemother , vol.42 , pp. 91-94
    • Oakley, K.L.1    Moore, C.B.2    Denning, D.W.3
  • 16
    • 0031797483 scopus 로고    scopus 로고
    • In vitro evaluation of voriconazole against clinical isolates of yeasts, moulds and dermatophytes in comparison with itraconazole, ketoconazole, amphotericin B and griseofulvin
    • Wildfeuer A, Seidl HP, Paule I, Haberreiter A In vitro evaluation of voriconazole against clinical isolates of yeasts, moulds and dermatophytes in comparison with itraconazole, ketoconazole, amphotericin B and griseofulvin. Mycoses. 41:1998;309-319.
    • (1998) Mycoses , vol.41 , pp. 309-319
    • Wildfeuer, A.1    Seidl, H.P.2    Paule, I.3    Haberreiter, A.4
  • 18
    • 0031688826 scopus 로고    scopus 로고
    • In vitro activities of amphotericin B, itraconazole and voriconazole against 150 clinical and environmental Aspergillju fumigatus isolates
    • Verweij PE, Mensink M, Rijs AJ, Donnelly JP, Meis JF, Denning DW In vitro activities of amphotericin B, itraconazole and voriconazole against 150 clinical and environmental Aspergillju fumigatus isolates. J Antimicrob Chemother. 43:1998;389-392.
    • (1998) J Antimicrob Chemother , vol.43 , pp. 389-392
    • Verweij, P.E.1    Mensink, M.2    Rijs, A.J.3    Donnelly, J.P.4    Meis, J.F.5    Denning, D.W.6
  • 29
    • 0031760635 scopus 로고    scopus 로고
    • In vitro susceptibilities of Candida blood stream isolates to the new triazole antifungal agents BMS-207147, Sch56592, and Voriconazole
    • Pfaller MA, Messer SA, Hollis RJ, Jones RN, Doern GV, Brandt ME, Hajjeh RA In vitro susceptibilities of Candida blood stream isolates to the new triazole antifungal agents BMS-207147, Sch56592, and Voriconazole. Antimicrob Agents Chemother. 42:1998;3242-3244.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3242-3244
    • Pfaller, M.A.1    Messer, S.A.2    Hollis, R.J.3    Jones, R.N.4    Doern, G.V.5    Brandt, M.E.6    Hajjeh, R.A.7
  • 33
    • 0031690304 scopus 로고    scopus 로고
    • Comparison of the in vitro activity of voriconazole (UK-109,496), itraconazole and amphotericin B against clinical isolates of Aspergillus fumigatus
    • Cuenca-Estrella M, Ropdriguez-Tudela JL, Mellado E, Martinez-Suarez JV, Monzon A Comparison of the in vitro activity of voriconazole (UK-109,496), itraconazole and amphotericin B against clinical isolates of Aspergillus fumigatus. J Antimicrob Chemother. 42:1998;531-533.
    • (1998) J Antimicrob Chemother , vol.42 , pp. 531-533
    • Cuenca-Estrella, M.1    Ropdriguez-Tudela, J.L.2    Mellado, E.3    Martinez-Suarez, J.V.4    Monzon, A.5
  • 34
    • 0031826841 scopus 로고    scopus 로고
    • Voriconazole against fluconazole-susceptible and resistant candida isolates: In vitro efficacy compared with that of itraconazole and ketoconazole
    • Nguyen MH, Yu CY Voriconazole against fluconazole-susceptible and resistant candida isolates: in vitro efficacy compared with that of itraconazole and ketoconazole. J Antimicrob Chemother. 42:1998;253-256.
    • (1998) J Antimicrob Chemother , vol.42 , pp. 253-256
    • Nguyen, M.H.1    Yu, C.Y.2
  • 35
    • 0031654590 scopus 로고    scopus 로고
    • In vitro activity of a new triazole antifungal agent, Sch 56592, against clinical isolates of filamentous fungi
    • Marco F, Pfaller MA, Messer SA, Jones RN In vitro activity of a new triazole antifungal agent, Sch 56592, against clinical isolates of filamentous fungi. Mycopathol. 141:1998;73-77.
    • (1998) Mycopathol , vol.141 , pp. 73-77
    • Marco, F.1    Pfaller, M.A.2    Messer, S.A.3    Jones, R.N.4
  • 37
    • 0028862822 scopus 로고
    • The AUR1 gene in Saccharomyces cerevisiae encodes dominant resistance to the antifungal agent aureobasidin A (LY295337)
    • Heidler SA, Radding JA The AUR1 gene in Saccharomyces cerevisiae encodes dominant resistance to the antifungal agent aureobasidin A (LY295337). Antimicrob Agents Chemother. 39:1995;2765-2769.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2765-2769
    • Heidler, S.A.1    Radding, J.A.2
  • 38
    • 0030970048 scopus 로고    scopus 로고
    • Sphingolipid synthesis as a target for antifungal drugs: Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene
    • Nagiec MM, Nagieec EE, Baltisberger JA, Wells GB, Lester RL, Dickson RC Sphingolipid synthesis as a target for antifungal drugs: complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J Biol Chem. 272:1997;9809-9817.
    • (1997) J Biol Chem , vol.272 , pp. 9809-9817
    • Nagiec, M.M.1    Nagieec, E.E.2    Baltisberger, J.A.3    Wells, G.B.4    Lester, R.L.5    Dickson, R.C.6
  • 41
    • 0031883556 scopus 로고    scopus 로고
    • Isolation and characterization of the aureobasidin A-resistant gene, aur1R, on Schizsaccharomyces pombe: Roles of Aur1p+ in cell morphogenesis
    • Hashido-Okado T, Hyasumoto R, Endo M, Takesako K, Kato I Isolation and characterization of the aureobasidin A-resistant gene, aur1R, on Schizsaccharomyces pombe: roles of Aur1p+ in cell morphogenesis. Curr Genet. 33:1998;38-45.
    • (1998) Curr Genet , vol.33 , pp. 38-45
    • Hashido-Okado, T.1    Hyasumoto, R.2    Endo, M.3    Takesako, K.4    Kato, I.5
  • 42
    • 0032992201 scopus 로고    scopus 로고
    • An aureobasidin A resistance gene isolated from Aspergillus is a homolog of yeast AUR1 , a gene responsible for inositol phosphrylceramide (IPC) synthase activity
    • Kuroda M, Hashida-Okado T, Yasumoto R, Kato GK, Takesako K An aureobasidin A resistance gene isolated from Aspergillus is a homolog of yeast AUR1 , a gene responsible for inositol phosphrylceramide (IPC) synthase activity. Mol Gen Genet. 261:1999;290-296.
    • (1999) Mol Gen Genet , vol.261 , pp. 290-296
    • Kuroda, M.1    Hashida-Okado, T.2    Yasumoto, R.3    Kato, G.K.4    Takesako, K.5
  • 43
    • 0031058460 scopus 로고    scopus 로고
    • Antifungals targeted to the cell wall
    • Georgopapadakou NH Antifungals targeted to the cell wall. Exp Opin Invest Drugs. 6:1997;147-150.
    • (1997) Exp Opin Invest Drugs , vol.6 , pp. 147-150
    • Georgopapadakou, N.H.1
  • 44
    • 0030730483 scopus 로고    scopus 로고
    • Echinocandins and pneumocandins - A new antifungal class with a novel mode of action
    • Denning DW Echinocandins and pneumocandins - a new antifungal class with a novel mode of action. J Antimicrob Chemother. 40:1997;611-614.
    • (1997) J Antimicrob Chemother , vol.40 , pp. 611-614
    • Denning, D.W.1
  • 46
    • 0027959267 scopus 로고
    • A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-β-D-glucan synthase
    • Douglas CM, Marrinan JA, Li W, Kurtz MB A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-β-D-glucan synthase. J Bacteriol. 176:1994;5686-5696.
    • (1994) J Bacteriol , vol.176 , pp. 5686-5696
    • Douglas, C.M.1    Marrinan, J.A.2    Li, W.3    Kurtz, M.B.4
  • 47
    • 0031981860 scopus 로고    scopus 로고
    • Photoaffinity analog of the semisynthetic echinocandin LY303366: Identification of echinocandin targets in Candida albicans
    • This paper identifies other proteins as potentially interacting with the echino/pneumocandins
    • Radding JA, Heidler SA, Turner WW Photoaffinity analog of the semisynthetic echinocandin LY303366: identification of echinocandin targets in Candida albicans. Antimicrob Agents Chemother. 42:1998;1187-1194. This paper identifies other proteins as potentially interacting with the echino/pneumocandins.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1187-1194
    • Radding, J.A.1    Heidler, S.A.2    Turner, W.W.3
  • 48
    • 0031691874 scopus 로고    scopus 로고
    • In vitro activity of the echinocandin antifungal agent LY303,366 in comparision with itraconazole and amphotericin B against Aspergillus spp
    • Oakley KL, Moore CB, Denning DW In vitro activity of the echinocandin antifungal agent LY303,366 in comparision with itraconazole and amphotericin B against Aspergillus spp. Antimicrob Agents Chemother. 42:1998;2726-2730.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2726-2730
    • Oakley, K.L.1    Moore, C.B.2    Denning, D.W.3
  • 49
    • 0031689491 scopus 로고    scopus 로고
    • Comparison of in vitro activities of the new triazole SCH 56592 and the echinocandins MK-0991 (L-743,872) and LY 303366 against opportunistic filamentous and dimorphic fungi and yeasts
    • Espinel-Ingroff A Comparison of in vitro activities of the new triazole SCH 56592 and the echinocandins MK-0991 (L-743,872) and LY 303366 against opportunistic filamentous and dimorphic fungi and yeasts. J Clin Microbiol. 36:1998;2950-2956.
    • (1998) J Clin Microbiol , vol.36 , pp. 2950-2956
    • Espinel-Ingroff, A.1
  • 51
    • 0031977161 scopus 로고    scopus 로고
    • Efficacy of LY303366 against amphotericin B-susceptible and -resistant Aspergillus fumigatus in murine model of invasive aseprgillosis
    • Verweij PE, Oakley KL, Morrissey J, Morrissey G, Denning DW Efficacy of LY303366 against amphotericin B-susceptible and -resistant Aspergillus fumigatus in murine model of invasive aseprgillosis. Antimicrob Agents Chemother. 42:1998;873-878.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 873-878
    • Verweij, P.E.1    Oakley, K.L.2    Morrissey, J.3    Morrissey, G.4    Denning, D.W.5
  • 52
    • 0032422450 scopus 로고    scopus 로고
    • Activity of MK-0991 (L-743,872), a new echinocandin, compared with those of LY303366 and four other antifungal agents testes against blood stream isolates of Candida spp
    • Marco F, Pfaller MA, Messer SA, Jones RN Activity of MK-0991 (L-743,872), a new echinocandin, compared with those of LY303366 and four other antifungal agents testes against blood stream isolates of Candida spp. Diagn Microbiol Infect Dis. 32:1998;33037.
    • (1998) Diagn Microbiol Infect Dis , vol.32 , pp. 33037
    • Marco, F.1    Pfaller, M.A.2    Messer, S.A.3    Jones, R.N.4
  • 55
    • 0031943562 scopus 로고    scopus 로고
    • In vitro activity of two echinocandin derivatives, LY303366 and MK0991 (L-743,792), against clinical isolates of Aspergillus, Fusarium, Rhizopus, and other filamentous fungi
    • Pfaller MA, Marco F, Messer SA, Jones RN In vitro activity of two echinocandin derivatives, LY303366 and MK0991 (L-743,792), against clinical isolates of Aspergillus, Fusarium, Rhizopus, and other filamentous fungi. Diagn Microbiol Infect Dis. 30:1998;251-255.
    • (1998) Diagn Microbiol Infect Dis , vol.30 , pp. 251-255
    • Pfaller, M.A.1    Marco, F.2    Messer, S.A.3    Jones, R.N.4
  • 62
    • 0028061202 scopus 로고
    • Nikkomycin Z is a specific inhibitor of Saccharomyces cerevisiae chitin synthase isozyme Chs3 in vitro and in vivo
    • Gaughran JP, Lai MH, Kirsch DR, Silverman SJ Nikkomycin Z is a specific inhibitor of Saccharomyces cerevisiae chitin synthase isozyme Chs3 in vitro and in vivo. J Bacteriol. 176:1994;5857-5860.
    • (1994) J Bacteriol , vol.176 , pp. 5857-5860
    • Gaughran, J.P.1    Lai, M.H.2    Kirsch, D.R.3    Silverman, S.J.4
  • 63
    • 0033067659 scopus 로고    scopus 로고
    • In vitro antifungal activity of nikkomycin Z in combination with fluconazole or itraconazole
    • Li RK, Rinaldi MG In vitro antifungal activity of nikkomycin Z in combination with fluconazole or itraconazole. Antimicrob Agents Chemother. 43:1999;1401-1405.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1401-1405
    • Li, R.K.1    Rinaldi, M.G.2
  • 64
    • 0030771531 scopus 로고    scopus 로고
    • Efficacy of nikkomycin Z against experimental pulmonary blastomycosis
    • Clemons KV, Stevens DA Efficacy of nikkomycin Z against experimental pulmonary blastomycosis. Antimicrob Agents Chemother. 41:1997;2026-2068.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2026-2068
    • Clemons, K.V.1    Stevens, D.A.2
  • 68
    • 33746433030 scopus 로고    scopus 로고
    • Pradimicin therapy of disseminated Candida tropicalis infection in the mouse
    • Restrepo MI, Najvar LK, Fothergill AW, Graybill JR Pradimicin therapy of disseminated Candida tropicalis infection in the mouse. Med Mycol. 36:1998;181-184.
    • (1998) Med Mycol , vol.36 , pp. 181-184
    • Restrepo, M.I.1    Najvar, L.K.2    Fothergill, A.W.3    Graybill, J.R.4
  • 70
    • 0031059838 scopus 로고    scopus 로고
    • Pradimicins: A novel class of broad-spectrum antifungal compounds
    • Walsh TJ, Giri N Pradimicins: a novel class of broad-spectrum antifungal compounds. Eur J Clin Microbiol Infect Dis. 16:1997;93-97.
    • (1997) Eur J Clin Microbiol Infect Dis , vol.16 , pp. 93-97
    • Walsh, T.J.1    Giri, N.2
  • 71
    • 0025182923 scopus 로고
    • Protein synthesis in yeast: Structural and functional analysis of the gene encoding elongation factor 3
    • Sandbaken MG, Lupisella JA, DiDomenico B, Chakraburtty K Protein synthesis in yeast: structural and functional analysis of the gene encoding elongation factor 3. J Biol Chem. 265:1990;15838-15844.
    • (1990) J Biol Chem , vol.265 , pp. 15838-15844
    • Sandbaken, M.G.1    Lupisella, J.A.2    Didomenico, B.3    Chakraburtty, K.4
  • 72
    • 0026521867 scopus 로고
    • Isolation and sequence analysis of the gene encoding translation elongation factor 3 from Candida albicans
    • DiDomenico BJ, Lupisella J, Sandbaken M, Chakraburtty K Isolation and sequence analysis of the gene encoding translation elongation factor 3 from Candida albicans. Yeast. 8:1992;337-352.
    • (1992) Yeast , vol.8 , pp. 337-352
    • Didomenico, B.J.1    Lupisella, J.2    Sandbaken, M.3    Chakraburtty, K.4
  • 73
    • 0033109295 scopus 로고    scopus 로고
    • Detection and analysis of translation elongation factor 3 genes from various yeasts
    • Uritani M, Shoumura Y, Yamada S Detection and analysis of translation elongation factor 3 genes from various yeasts. Biosci Biotechnol Biochem. 63:1999;769-772.
    • (1999) Biosci Biotechnol Biochem , vol.63 , pp. 769-772
    • Uritani, M.1    Shoumura, Y.2    Yamada, S.3
  • 77
    • 0032488918 scopus 로고    scopus 로고
    • Elongation factor 2 as a novel target for selective inhibition of fungal protein synthesis
    • Justice MC, Hsu M-J, Tse B, Ku T, Balkovec J, Schmatz D, Nielsen J Elongation factor 2 as a novel target for selective inhibition of fungal protein synthesis. J Biol Chem. 273:1998;3148-3151.
    • (1998) J Biol Chem , vol.273 , pp. 3148-3151
    • Justice, M.C.1    Hsu, M.-J.2    Tse, B.3    Ku, T.4    Balkovec, J.5    Schmatz, D.6    Nielsen, J.7
  • 78
    • 0040837015 scopus 로고    scopus 로고
    • Identification of elongation factor 2 as the essential protein targeted by sordarins in Candida albicans
    • This paper first identified EF2 as the soluble factor from Candida as binding to sordarin
    • Dominguez JM, Martin JJ Identification of elongation factor 2 as the essential protein targeted by sordarins in Candida albicans. Antimicrob Agents Chemother. 42:1998;2279-2283. This paper first identified EF2 as the soluble factor from Candida as binding to sordarin.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2279-2283
    • Dominguez, J.M.1    Martin, J.J.2
  • 79
    • 0033582531 scopus 로고    scopus 로고
    • Mutations in ribosomal protein L10e confer resistance to the fungal-specific eukaryotic elongation factor 2 inhibitor sordarin
    • This paper suggests that sordarins may interact with other ribosomal proteins to enhance specificity
    • Justice MC, Ku T, Hsu MJ, Carniol K, Schmatz D, Nielsen JL Mutations in ribosomal protein L10e confer resistance to the fungal-specific eukaryotic elongation factor 2 inhibitor sordarin. J Biol Chem. 274:1999;4869-4875. This paper suggests that sordarins may interact with other ribosomal proteins to enhance specificity.
    • (1999) J Biol Chem , vol.274 , pp. 4869-4875
    • Justice, M.C.1    Ku, T.2    Hsu, M.J.3    Carniol, K.4    Schmatz, D.5    Nielsen, J.L.6
  • 80
    • 0032566536 scopus 로고    scopus 로고
    • Ribosomal P-protein stalk function is targeted by sordarin antifungals
    • Gomez-Lorenzo MG, Garcia-Bustos JF Ribosomal P-protein stalk function is targeted by sordarin antifungals. J Biol Chem. 273:1998;25041-25044.
    • (1998) J Biol Chem , vol.273 , pp. 25041-25044
    • Gomez-Lorenzo, M.G.1    Garcia-Bustos, J.F.2
  • 82
    • 0028053746 scopus 로고
    • Targeted gene replacement demonstrates that myristoyl-CoA:protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans
    • Lodge JK, Jackson-Machelski E, Toffaletti KL, Perfect JR, Gordon JI Targeted gene replacement demonstrates that myristoyl-CoA:protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. Proc Natl Acad Sci USA. 91:1994;12008-12012.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12008-12012
    • Lodge, J.K.1    Jackson-Machelski, E.2    Toffaletti, K.L.3    Perfect, J.R.4    Gordon, J.I.5
  • 83
    • 0029070249 scopus 로고
    • Genetic studies reveal that myristoylCoA:protein N-myristoyltransferase is an essential enzyme in Candida albicans
    • Weinberg RA, McWherter CA, Freeman SK, Wood DC, Gordon JI, Lee SC Genetic studies reveal that myristoylCoA:protein N-myristoyltransferase is an essential enzyme in Candida albicans. Mol Microbiol. 6:1995;241-250.
    • (1995) Mol Microbiol , vol.6 , pp. 241-250
    • Weinberg, R.A.1    McWherter, C.A.2    Freeman, S.K.3    Wood, D.C.4    Gordon, J.I.5    Lee, S.C.6
  • 84
    • 0028000667 scopus 로고
    • Comparison of myristoyl CoA:protein N-myristoyltransferases from three pathogenic fungi - Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans
    • Lodge JK, Hohnson RL, Weinberg RA, Gordon JI Comparison of myristoyl CoA:protein N-myristoyltransferases from three pathogenic fungi - Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans. J Biol Chem. 269:1994;2996-3009.
    • (1994) J Biol Chem , vol.269 , pp. 2996-3009
    • Lodge, J.K.1    Hohnson, R.L.2    Weinberg, R.A.3    Gordon, J.I.4
  • 85
    • 85030364529 scopus 로고    scopus 로고
    • Saccharomyces Genome Database on World Wide Web URL:
    • Saccharomyces Genome Database on World Wide Web URL: http://genome-www.stanford.edu/Saccharomyces.
  • 86
    • 15144355281 scopus 로고    scopus 로고
    • Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibtors with mechanism-based antifungal activity
    • Devadas B, Freeman SK, Zupec ME, Lu HF, Nagarajan SR, Kishore NS, Lodge JK, Luneman DW, McWherter CA, Vinjamoori DVet al. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibtors with mechanism-based antifungal activity. J Med Chem. 40:1997;2609-2625.
    • (1997) J Med Chem , vol.40 , pp. 2609-2625
    • Devadas, B.1    Freeman, S.K.2    Zupec, M.E.3    Lu, H.F.4    Nagarajan, S.R.5    Kishore, N.S.6    Lodge, J.K.7    Luneman, D.W.8    McWherter, C.A.9    Vinjamoori, D.V.10
  • 87
    • 0032510384 scopus 로고    scopus 로고
    • Novel biologically active nonpeptidic inhibitors of myristoylCoA:protein N-myristoyltransferase
    • This paper describes non-peptidomimetic inhibitors of NMT1 that are active in vitro
    • Devadas B, Freeman SK, McWherter CA, Kishore NS, Lodge JK, Jackson-Machelski E, Gordon JI, Sikorski JA Novel biologically active nonpeptidic inhibitors of myristoylCoA:protein N-myristoyltransferase. J Med Chem. 41:1998;996-1000. This paper describes non-peptidomimetic inhibitors of NMT1 that are active in vitro.
    • (1998) J Med Chem , vol.41 , pp. 996-1000
    • Devadas, B.1    Freeman, S.K.2    McWherter, C.A.3    Kishore, N.S.4    Lodge, J.K.5    Jackson-Machelski, E.6    Gordon, J.I.7    Sikorski, J.A.8
  • 89
    • 85030365000 scopus 로고    scopus 로고
    • Candida albicans Information on World Wide Web URL:
    • Candida albicans Information on World Wide Web URL: http://alces.med.umn.edu/Candida.html.
  • 90
    • 85030363148 scopus 로고    scopus 로고
    • Fungal Genome Resource on World Wide Web URL:
    • Fungal Genome Resource on World Wide Web URL: http://fungus.genetics.uga.edu:5080/.
  • 91
    • 85030367358 scopus 로고    scopus 로고
    • Cryptococcus neoformans cDNA Sequencing on World Wide Web URL:
    • Cryptococcus neoformans cDNA Sequencing on World Wide Web URL: http://www.genome.ou.edu/cneo.html.
  • 92
    • 85030365858 scopus 로고    scopus 로고
    • Fusarium sporotrichioides cDNA Sequencing on World Wide Web UTL:
    • Fusarium sporotrichioides cDNA Sequencing on World Wide Web UTL: http://www.genome.ou.edu/fsporo.html.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.