-
2
-
-
0032240957
-
Molecular biology of the estrogen receptor aids in the understanding of tamoxifen resistance and breast cancer prevention with raloxifene
-
(1998)
Cancer Res
, vol.152
, pp. 265-276
-
-
Jordan, V.C.1
-
23
-
-
0026776424
-
Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
-
(1992)
Cell
, vol.69
, pp. 205-216
-
-
Peles, E.1
Bacus, S.S.2
Koski, R.A.3
-
24
-
-
0026776717
-
Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
-
(1992)
Cell
, vol.69
, pp. 559-572
-
-
Wen, D.1
Peles, E.2
Cupples, R.3
-
25
-
-
0033604516
-
The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis
-
(1999)
Exp Cell Res
, vol.253
, pp. 78-87
-
-
Kim, H.1
Muller, W.J.2
-
28
-
-
0033747558
-
Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4217-4225
-
-
Pawlowski, V.1
Revillion, F.2
Hebbar, M.3
-
29
-
-
0024023873
-
EGF binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3
-
(1988)
EMBO J
, vol.7
, pp. 1647-1651
-
-
King, C.R.1
Borrello, I.2
Bellot, F.3
-
30
-
-
0033654451
-
The erbB/HER family of receptor tyrosine kinases: A potential target for chemoprevention of epithelial neoplasms
-
(2000)
J Cell Biochem
, vol.34
, Issue.SUPPL.
, pp. 52-60
-
-
Kirschbaum, M.H.1
Yarden, Y.2
-
37
-
-
0030942007
-
Clinical and prognostic significance of the expression of the c-erbB-2 and c-erbB 3 oncoproteins in primary and metastatic malignant melanomas and breast carcinomas
-
(1997)
Anticancer Res
, vol.17
, pp. 1319-1330
-
-
Bodey, B.1
Bodey B., Jr.2
Groger, A.M.3
-
44
-
-
0024395587
-
Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts
-
(1989)
Cell
, vol.58
, pp. 287-292
-
-
Kokai, Y.1
Myers, J.N.2
Wada, T.3
-
45
-
-
0028352507
-
Protein tyrosine kinases as therapeutic targets in cancer chemotherapy and recent advances in the development of new inhibitors
-
(1994)
Expert Opin Invest Drugs
, vol.3
, pp. 577-595
-
-
Fry, D.W.1
-
48
-
-
0032695910
-
Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: Dynamics of receptor inhibition in situ and antitumor effects in athymic mice
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 739-748
-
-
Pollack, V.A.1
Savage, D.M.2
Baker, D.A.3
-
52
-
-
0345563219
-
The combination of in situ hybridization and immunohistochemical analysis: An evaluation of Her2/neu expression in paraffin-embedded breast carcinomas and adjacent normal-appearing breast epithelium
-
(1997)
Mod Pathol
, vol.10
, pp. 1247-1252
-
-
Ratcliffe, N.1
Wells, W.2
Wheeler, K.3
-
55
-
-
0024310601
-
Epidermal growth factor receptor in human breast cancer. Recent results
-
(1989)
Cancer Res
, vol.113
, pp. 70-77
-
-
Harris, A.L.1
-
63
-
-
0033757346
-
Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents
-
Drugs
, vol.60
, Issue.SUPPL. 1
, pp. 25-32
-
-
Ciardiello, F.1
-
64
-
-
0029961912
-
A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis
-
(1996)
Cancer Res
, vol.56
, pp. 5079-5086
-
-
Nagane, M.1
Coufal, F.2
Lin, H.3
-
69
-
-
0028301750
-
Prognostic significance of HER-2/neu oncoprotein expression in node-positive breast cancer: The influence of the pattern of immunostaining and adjuvant therapy
-
(1994)
Cancer
, vol.73
, pp. 2359-2365
-
-
Tetu, B.1
Brisson, J.2
-
72
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
73
-
-
0032844121
-
Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer
-
Herceptin Multinational Investigator Study Group
-
Semin Oncol
, vol.26
, Issue.SUPPL. 12
, pp. 71-77
-
-
Shak, S.1
-
74
-
-
0032895235
-
Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
-
(1999)
Clin Ther
, vol.21
, pp. 309-318
-
-
Goldenberg, M.M.1
-
75
-
-
0031903646
-
Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
-
(1998)
J Clin Oncol
, vol.16
, pp. 2659-2671
-
-
Pegram, M.D.1
Lipton, A.2
Hayes, D.F.3
-
76
-
-
0032127350
-
Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
-
(1998)
Cancer Res
, vol.58
, pp. 2825-2831
-
-
Baselga, J.1
Norton, L.2
Albanell, J.3
-
80
-
-
0032874107
-
Cardiotoxicity in patients receiving trastuzumab (Herceptin): Primary toxicity, synergistic or sequential stress, or surveillance artifact?
-
(1999)
Semin Oncol
, vol.26
, Issue.SUPPL. 12
, pp. 96-101
-
-
Ewer, M.S.1
Gibbs, H.R.2
Swafford, J.3
-
81
-
-
0000405942
-
Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer markedly increases anticancer activity: A randomized, multinational controlled phase III trial
-
abstr 377
-
(1998)
Proc Am Soc Clin Oncol
, vol.17
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
82
-
-
0033561296
-
Elevated expression of activated forms of neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: Implications for human breast cancer
-
(1999)
EMBO J
, vol.18
, pp. 2149-2164
-
-
Siegel, P.M.1
Ryan, E.D.2
Cardiff, R.D.3
-
98
-
-
0028120910
-
Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members
-
(1994)
Mol Cell Biol
, vol.14
, pp. 492-500
-
-
Fedi, P.1
Pierce, J.H.2
DiFiore, P.P.3
-
101
-
-
0033372557
-
Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4164-4174
-
-
Xia, W.1
Lau, Y.K.2
Zhang, H.Z.3
-
102
-
-
0030893008
-
Structure-based design of a potent, selective, and irreversible inhibitor of the catalytic domain of the erbB receptor subfamily of protein tyrosine kinases
-
(1997)
J Med Chem
, vol.40
, pp. 1130-1135
-
-
Singh, J.1
Dobrusin, E.M.2
Fry, D.W.3
-
104
-
-
0032053944
-
Downmodulation of TGF-alpha protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells
-
(1998)
J Cell Biochem
, vol.69
, pp. 55-62
-
-
Grandis, J.R.1
Chakraborty, A.2
Zeng, Q.3
-
105
-
-
0034043977
-
Site-directed irreversible inhibitors of the erbB family of receptor tyrosine kinases as novel chemotherapeutic agents for cancer
-
(2000)
Anticancer Drug Des
, vol.15
, pp. 3-16
-
-
Fry, D.W.1
|