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Volumn 29, Issue 3 SUPPL. 11, 2002, Pages 11-21

Potential benefits of the irreversible Pan-erbB inhibitor, CI-1033, in the treatment of breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

CANERTINIB; CYCLOPHOSPHAMIDE; DIPHENHYDRAMINE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; PACLITAXEL; PROTEIN KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STEROID; TRASTUZUMAB;

EID: 0036316380     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0093-7754(02)70122-x     Document Type: Conference Paper
Times cited : (111)

References (108)
  • 2
    • 0032240957 scopus 로고    scopus 로고
    • Molecular biology of the estrogen receptor aids in the understanding of tamoxifen resistance and breast cancer prevention with raloxifene
    • (1998) Cancer Res , vol.152 , pp. 265-276
    • Jordan, V.C.1
  • 16
    • 0021273420 scopus 로고
    • Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
    • (1984) Nature , vol.309 , pp. 418-425
    • Ullrich, A.1    Coussens, L.2    Hayflick, J.S.3
  • 20
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3
  • 23
    • 0026776424 scopus 로고
    • Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
    • (1992) Cell , vol.69 , pp. 205-216
    • Peles, E.1    Bacus, S.S.2    Koski, R.A.3
  • 24
    • 0026776717 scopus 로고
    • Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
    • (1992) Cell , vol.69 , pp. 559-572
    • Wen, D.1    Peles, E.2    Cupples, R.3
  • 25
    • 0033604516 scopus 로고    scopus 로고
    • The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis
    • (1999) Exp Cell Res , vol.253 , pp. 78-87
    • Kim, H.1    Muller, W.J.2
  • 28
    • 0033747558 scopus 로고    scopus 로고
    • Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay
    • (2000) Clin Cancer Res , vol.6 , pp. 4217-4225
    • Pawlowski, V.1    Revillion, F.2    Hebbar, M.3
  • 29
    • 0024023873 scopus 로고
    • EGF binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3
    • (1988) EMBO J , vol.7 , pp. 1647-1651
    • King, C.R.1    Borrello, I.2    Bellot, F.3
  • 30
    • 0033654451 scopus 로고    scopus 로고
    • The erbB/HER family of receptor tyrosine kinases: A potential target for chemoprevention of epithelial neoplasms
    • (2000) J Cell Biochem , vol.34 , Issue.SUPPL. , pp. 52-60
    • Kirschbaum, M.H.1    Yarden, Y.2
  • 37
    • 0030942007 scopus 로고    scopus 로고
    • Clinical and prognostic significance of the expression of the c-erbB-2 and c-erbB 3 oncoproteins in primary and metastatic malignant melanomas and breast carcinomas
    • (1997) Anticancer Res , vol.17 , pp. 1319-1330
    • Bodey, B.1    Bodey B., Jr.2    Groger, A.M.3
  • 43
    • 0030064531 scopus 로고    scopus 로고
    • Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 and HER2
    • (1996) J Biol Chem , vol.271 , pp. 3884-3890
    • Zhang, K.1    Sun, J.2    Liu, N.3
  • 44
    • 0024395587 scopus 로고
    • Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts
    • (1989) Cell , vol.58 , pp. 287-292
    • Kokai, Y.1    Myers, J.N.2    Wada, T.3
  • 45
    • 0028352507 scopus 로고
    • Protein tyrosine kinases as therapeutic targets in cancer chemotherapy and recent advances in the development of new inhibitors
    • (1994) Expert Opin Invest Drugs , vol.3 , pp. 577-595
    • Fry, D.W.1
  • 48
    • 0032695910 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor-associated tyrosine phosphorylation in human carcinomas with CP-358,774: Dynamics of receptor inhibition in situ and antitumor effects in athymic mice
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 739-748
    • Pollack, V.A.1    Savage, D.M.2    Baker, D.A.3
  • 49
    • 0032528051 scopus 로고    scopus 로고
    • Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1080-1087
    • He, Y.1    Zeng, Q.2    Drenning, S.D.3
  • 52
    • 0345563219 scopus 로고    scopus 로고
    • The combination of in situ hybridization and immunohistochemical analysis: An evaluation of Her2/neu expression in paraffin-embedded breast carcinomas and adjacent normal-appearing breast epithelium
    • (1997) Mod Pathol , vol.10 , pp. 1247-1252
    • Ratcliffe, N.1    Wells, W.2    Wheeler, K.3
  • 55
    • 0024310601 scopus 로고
    • Epidermal growth factor receptor in human breast cancer. Recent results
    • (1989) Cancer Res , vol.113 , pp. 70-77
    • Harris, A.L.1
  • 63
    • 0033757346 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents
    • Drugs , vol.60 , Issue.SUPPL. 1 , pp. 25-32
    • Ciardiello, F.1
  • 64
    • 0029961912 scopus 로고    scopus 로고
    • A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis
    • (1996) Cancer Res , vol.56 , pp. 5079-5086
    • Nagane, M.1    Coufal, F.2    Lin, H.3
  • 69
    • 0028301750 scopus 로고
    • Prognostic significance of HER-2/neu oncoprotein expression in node-positive breast cancer: The influence of the pattern of immunostaining and adjuvant therapy
    • (1994) Cancer , vol.73 , pp. 2359-2365
    • Tetu, B.1    Brisson, J.2
  • 72
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 73
    • 0032844121 scopus 로고    scopus 로고
    • Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer
    • Herceptin Multinational Investigator Study Group
    • Semin Oncol , vol.26 , Issue.SUPPL. 12 , pp. 71-77
    • Shak, S.1
  • 74
    • 0032895235 scopus 로고    scopus 로고
    • Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
    • (1999) Clin Ther , vol.21 , pp. 309-318
    • Goldenberg, M.M.1
  • 75
    • 0031903646 scopus 로고    scopus 로고
    • Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
    • (1998) J Clin Oncol , vol.16 , pp. 2659-2671
    • Pegram, M.D.1    Lipton, A.2    Hayes, D.F.3
  • 76
    • 0032127350 scopus 로고    scopus 로고
    • Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts
    • (1998) Cancer Res , vol.58 , pp. 2825-2831
    • Baselga, J.1    Norton, L.2    Albanell, J.3
  • 80
    • 0032874107 scopus 로고    scopus 로고
    • Cardiotoxicity in patients receiving trastuzumab (Herceptin): Primary toxicity, synergistic or sequential stress, or surveillance artifact?
    • (1999) Semin Oncol , vol.26 , Issue.SUPPL. 12 , pp. 96-101
    • Ewer, M.S.1    Gibbs, H.R.2    Swafford, J.3
  • 81
    • 0000405942 scopus 로고    scopus 로고
    • Addition of Herceptin (humanized anti-HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer markedly increases anticancer activity: A randomized, multinational controlled phase III trial
    • abstr 377
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 82
    • 0033561296 scopus 로고    scopus 로고
    • Elevated expression of activated forms of neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: Implications for human breast cancer
    • (1999) EMBO J , vol.18 , pp. 2149-2164
    • Siegel, P.M.1    Ryan, E.D.2    Cardiff, R.D.3
  • 92
  • 93
    • 0033523775 scopus 로고    scopus 로고
    • ErbB 4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation
    • (1999) J Cell Biol , vol.147 , pp. 77-88
    • Jones, F.E.1    Welte, T.2    Fu, X.Y.3
  • 94
    • 0032718015 scopus 로고    scopus 로고
    • Ribozyme-mediated down-regulation of ErbB-4 in estrogen receptor-positive breast cancer cells inhibits proliferation both in vitro and in vivo
    • (1999) Cancer Res , vol.59 , pp. 5315-5322
    • Tang, C.K.1    Concepcion, X.Z.2    Milan, M.3
  • 97
    • 0025690737 scopus 로고
    • Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: A mechanism for receptor transregulation
    • (1990) Biochemistry , vol.29 , pp. 11024-11028
    • Goldman, R.1    Levy, R.B.2    Peles, E.3
  • 98
    • 0028120910 scopus 로고
    • Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members
    • (1994) Mol Cell Biol , vol.14 , pp. 492-500
    • Fedi, P.1    Pierce, J.H.2    DiFiore, P.P.3
  • 101
    • 0033372557 scopus 로고    scopus 로고
    • Combination of EGFR, HER-2/neu, and HER-3 is a stronger predictor for the outcome of oral squamous cell carcinoma than any individual family members
    • (1999) Clin Cancer Res , vol.5 , pp. 4164-4174
    • Xia, W.1    Lau, Y.K.2    Zhang, H.Z.3
  • 102
    • 0030893008 scopus 로고    scopus 로고
    • Structure-based design of a potent, selective, and irreversible inhibitor of the catalytic domain of the erbB receptor subfamily of protein tyrosine kinases
    • (1997) J Med Chem , vol.40 , pp. 1130-1135
    • Singh, J.1    Dobrusin, E.M.2    Fry, D.W.3
  • 104
    • 0032053944 scopus 로고    scopus 로고
    • Downmodulation of TGF-alpha protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cells
    • (1998) J Cell Biochem , vol.69 , pp. 55-62
    • Grandis, J.R.1    Chakraborty, A.2    Zeng, Q.3
  • 105
    • 0034043977 scopus 로고    scopus 로고
    • Site-directed irreversible inhibitors of the erbB family of receptor tyrosine kinases as novel chemotherapeutic agents for cancer
    • (2000) Anticancer Drug Des , vol.15 , pp. 3-16
    • Fry, D.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.