How knockout mouse lines will be used to study the role of drug-metabolizing enzymes and their receptors during reproduction and development, and in environmental toxicity, cancer, and oxidative stress

Biochemical Pharmacology

Volumn 53, Issue 3, 1997, Pages 249-254

  Nebert, D W ^a   Duffy, J J ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Ah receptor; Cre recombinase; dioxin; drug metabolizing enzymes; loxP sites; mouse genetics; polycyclic aromatic hydrocarbons; Ah gene battery

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALDEHYDE DEHYDROGENASE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450; DRUG METABOLIZING ENZYME; ENVIRONMENTAL POISON; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HYMECROMONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL MODEL; CANCER; CELL TYPE; DEVELOPMENT; ENZYME SUBSTRATE; GENE DISRUPTION; GENE INDUCTION; GENETICS; LETHALITY; METHODOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; POLLUTION; PRIORITY JOURNAL; REPRODUCTION; REVIEW;

EID: 0031054440     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00740-X     Document Type: Note

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