Fly-ing from genes to drugs

Trends in Molecular Medicine

Volumn 8, Issue 3, 2002, Pages 99-101

  Chan, H Y Edwin ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; DIELDRIN; FATTY ACID; HISTONE DEACETYLASE INHIBITOR; HUNTINGTIN; LORENZO OIL; POLYGLUTAMINE; TYRAMINE; TYROSINE;

ACETYLATION; ADRENOLEUKODYSTROPHY; ALCOHOLISM; ARTICLE; COCAINE DEPENDENCE; DROSOPHILA MELANOGASTER; GENETIC ANALYSIS; HUMAN; HUNTINGTON CHOREA; INSECTICIDE RESISTANCE; MEDICAL RESEARCH; NEUROLOGIC DISEASE; PATHOGENESIS; PREVENTIVE MEDICINE;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0036090791     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(02)02292-X     Document Type: Short Survey

References (22)

1. Glutamine repeats and neurodegeneration
2. Drosophila models of neurodegenerative disease
3. Identification of genes that modify ataxin-1-induced neurodegeneration
4. Genetic suppression of polyglutamine toxicity in Drosophila
5. Mechanisms of chaperone suppression of polyglutamine disease: Selectivity, synergy, and modulation of protein solubility in Drosophila
6. Genetic mapping with SNP markers in Drosophila
7. A rapid method to map mutations in Drosophila
8. Single nucleotide polymorphism markers for genetic mapping in Drosophila melanogaster
9. CREB-binding protein sequestration by expanded polyglutamine
10. Interferenceby huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
11. CBP, a transcriptional coactivator and acetyltransferase
12. The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
13. Altered transcription in yeast expressing expanded polyglutamine
14. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
15. Histone deacetylase inhibitors reduce polyglutamine toxicity
16. Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL
17. dSIR2 and dHDAC6: Two novel, inhibitor-resistant deacetylases in Drosophila melanogaster
18. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening
19. Preventing neurodegeneration in the Drosophila mutant bubblegum
20. Ethanol intoxification in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway
21. The trace amine tyramine is essential for sensitization of cocaine in Drosophila
22. A single-amino acid substitution in a γ-aminobutyric acid subtype A receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations