-
3
-
-
0021442649
-
Ordered rearrangement of immunoglobulin heavy chain variable region segments
-
(1984)
EMBO J.
, vol.3
, pp. 1209-1219
-
-
Alt, F.W.1
Yancopoulos, G.D.2
Blackwell, T.K.3
Wood, C.4
Thomas, E.5
Boss, M.6
Coffman, R.7
Rosenberg, N.8
Tonegawa, S.9
-
5
-
-
0032142797
-
Developmentally programmed rearrangement of T cell receptor Vγ genes is controlled by sequences immediately upstream of the Vγ genes
-
(1998)
Immunity
, vol.9
, pp. 159-168
-
-
Baker, J.E.1
Cado, D.2
Raulet, D.H.3
-
7
-
-
0034650907
-
Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expresssing B cells in mice
-
(2000)
J. Immunol.
, vol.164
, pp. 893-899
-
-
Barreto, V.1
Cumano, A.2
-
8
-
-
0034214049
-
Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule
-
(2000)
Nature
, vol.405
, pp. 583-586
-
-
Bassing, C.H.1
Alt, F.W.2
Hughes, M.M.3
D'Auteuil, M.4
Wehrly, T.5
Woodman, B.B.6
Gartner, F.7
White, J.M.8
Davidson, L.9
Sleckman, B.P.10
-
14
-
-
0034623860
-
Response to RAG-mediated V(D)J cleavage by NBS1 and γ-H2AX
-
(2000)
Science
, vol.290
, pp. 1962-1964
-
-
Chen, H.T.1
Bhandoola, A.2
Difilippantonio, M.J.3
Zhu, J.4
Brown, M.J.5
Tai, X.6
Rogakou, E.P.7
Brotz, T.M.8
Bonner, W.M.9
Ried, T.10
Nussenzweig, A.11
-
17
-
-
0034732239
-
DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
-
(2000)
Nature
, vol.404
, pp. 510-514
-
-
Difilippantonio, M.J.1
Zhu, J.2
Chen, H.T.3
Meffre, E.4
Nussenzweig, M.C.5
Max, E.E.6
Ried, T.7
Nussenzweig, A.8
-
20
-
-
0035839840
-
DNA double-strand break repair and chromosomal translocation: Lessons from animal models
-
(2001)
Oncogene
, vol.20
, pp. 5572-5579
-
-
Ferguson, D.O.1
Alt, F.W.2
-
21
-
-
0032511976
-
Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV
-
(1998)
Nature
, vol.396
, pp. 173-177
-
-
Frank, K.M.1
Sekiguchi, J.M.2
Seidl, K.J.3
Swat, W.4
Rathbun, G.A.5
Cheng, H.-L.6
Davidson, L.7
Kangaloo, L.8
Alt, F.W.9
-
22
-
-
0033634973
-
DNA Ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway
-
(2000)
Mol. Cell
, vol.5
, pp. 993-1002
-
-
Frank, K.M.1
Sharpless, N.E.2
Gao, Y.3
Sekiguchi, J.M.4
Ferguson, D.O.5
Zhu, C.6
Manis, J.P.7
Horner, J.8
DePinho, R.A.9
Alt, F.W.10
-
26
-
-
0032417640
-
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis
-
(1998)
Cell
, vol.95
, pp. 891-902
-
-
Gao, Y.1
Sun, Y.2
Frank, K.M.3
Dikkes, P.4
Fujiwara, Y.5
Seidl, K.J.6
Sekiguchi, J.M.7
Rathbun, G.8
Swat, W.9
Wang, J.10
-
27
-
-
0034690249
-
Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability, and development
-
(2000)
Nature
, vol.404
, pp. 897-900
-
-
Gao, Y.1
Ferguson, D.O.2
Xie, W.3
Manis, J.P.4
Sekiguchi, J.5
Frank, K.M.6
Chaudhuri, J.7
Horner, J.8
DePinho, R.A.9
Alt, F.W.10
-
34
-
-
0031433517
-
Growth retardation and leaky SCID phenotype of Ku70-deficient mice
-
(1997)
Immunity
, vol.7
, pp. 653-655
-
-
Gu, Y.1
Seidl, K.J.2
Rathbun, G.3
Zhu, C.4
Manis, J.P.5
Van der Stoop, N.6
Davidson, L.7
Cheng, H.-L.8
Sekiguchi, J.9
Frank, K.10
-
35
-
-
0034646304
-
Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2668-2673
-
-
Gu, Y.1
Sekiguchi, J.2
Gao, Y.3
Dikkes, P.4
Frank, K.5
Ferguson, D.6
Hasty, P.7
Chun, J.8
Alt, F.W.9
-
48
-
-
0033574001
-
Catalytic subunit of DNA-dependent protein kinase: Impact on lymphocyte development and tumorigenesis
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1403-1408
-
-
Kurimasa, A.1
Ouyang, H.2
Dong, L.-J.3
Wang, S.4
Li, X.5
Cordon-Cardo, C.6
Chen, D.J.7
Li, G.C.8
-
53
-
-
0033427205
-
Cyclin A/CDK2 regulates V(D)J recombination by coordinating RAG-2 accumulation and DNA repair
-
(1999)
Immunity
, vol.11
, pp. 771-781
-
-
Lee, J.1
Desiderio, S.2
-
54
-
-
0028048275
-
The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
-
(1994)
Adv. Immunol.
, vol.56
, pp. 27-149
-
-
Lewis, S.M.1
-
56
-
-
0029585872
-
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
-
(1995)
Cell
, vol.83
, pp. 1079-1089
-
-
Li, Z.1
Otevrel, T.2
Gao, Y.3
Cheng, H.-L.4
Seed, B.5
Stamato, T.D.6
Taccioli, G.E.7
Alt, F.W.8
-
64
-
-
0034625261
-
RAG1/2-mediated resolution of transposition intermediates: Two pathways and possible consequences
-
(2000)
Cell
, vol.101
, pp. 625-633
-
-
Melek, M.1
Gellert, M.2
-
67
-
-
0033180183
-
RAG2:gfp knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues
-
(1999)
Immunity
, vol.11
, pp. 201-212
-
-
Monroe, R.J.1
Seidl, K.J.2
Gaertner, F.3
Han, S.4
Chen, F.5
Sekiguchi, J.6
Wang, J.7
Ferrini, R.8
Davidson, L.9
Kelsoe, G.10
Alt, F.W.11
-
68
-
-
0035917489
-
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
Callebaut, I.2
De Chasseval, R.3
Corneo, B.4
Cavazzana-Calvo, M.5
Le Deist, F.6
Tezcan, I.7
Sanai, O.8
Bertrand, Y.9
Philippe, N.10
-
70
-
-
0035829551
-
Asynchronous replication and allelic exclusion in the immune system
-
(2001)
Nature
, vol.414
, pp. 221-225
-
-
Mostoslavsky, R.1
Singh, N.2
Tenzen, T.3
Goldmit, M.4
Gabay, C.5
Elizur, S.6
Qi, P.7
Reubinoff, B.E.8
Chess, A.9
Cedar, H.10
Bergman, Y.11
-
75
-
-
0030885974
-
Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination in vivo
-
(1997)
J. Exp. Med.
, vol.186
, pp. 921-929
-
-
Ouyang, H.1
Nussenzweig, A.2
Kurisama, A.3
Soares, V.C.4
Li, X.5
Cordon-Cardo, C.6
Li, W.7
Cheong, N.8
Nussenzweig, M.9
Iliakis, G.10
-
76
-
-
0035977089
-
New glimpses of an old machine
-
(2001)
Cell
, vol.107
, pp. 563-565
-
-
Paull, T.T.1
-
78
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
83
-
-
10144253125
-
RAG mutations in human B cell-negative SCID
-
(1996)
Science
, vol.274
, pp. 97-99
-
-
Schwarz, K.1
Gauss, G.H.2
Ludwig, L.3
Pannicke, U.4
Li, Z.5
Linder, D.6
Friedrich, W.7
Seger, R.A.8
Hansen-Hagge, T.E.9
Desiderio, S.10
-
85
-
-
0035172159
-
+ thymocyte: Implications for a new aspect in the regulation of TCR β gene recombination
-
(2001)
Int. Immunol.
, vol.13
, pp. 1405-1414
-
-
Senoo, M.1
Mochida, N.2
Wang, L.3
Matsumura, Y.4
Suzuki, D.5
Takeda, N.6
Shinkai, Y.7
Habu, S.8
-
86
-
-
0026581936
-
RAG-2 deficient mice lack mature lymphocytes owing to inability to initiate V(D)J recombination
-
(1992)
Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.-P.3
Oltz, E.M.4
Stewart, V.5
Mendelsohn, M.6
Charron, J.7
Datta, M.8
Stall, A.M.9
Alt, F.W.10
-
87
-
-
0035554683
-
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes
-
(2001)
Nat. Immunol.
, vol.2
, pp. 848-854
-
-
Skok, J.A.1
Brown, K.E.2
Azuara, V.3
Caparros, M.-L.4
Baxtor, J.5
Takacs, K.6
Dillon, N.7
Gray, D.8
Perry, R.P.9
Merkenschlager, M.10
Fisher, A.G.11
-
91
-
-
0034608888
-
Mechanisms that direct ordered assembly of T cell receptor β locus V, D, and J gene segments
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7975-7980
-
-
Sleckman, B.P.1
Bassing, C.H.2
Hughes, M.M.3
Okada, A.4
D'Auteuil, M.D.5
Wehrly, T.6
Woodman, B.B.7
Davidson, L.8
Chen, J.9
Alt, F.W.10
-
95
-
-
0032167545
-
Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity
-
(1998)
Immunity
, vol.9
, pp. 355-366
-
-
Taccioli, G.E.1
Amatucci, A.G.2
Beamish, H.J.3
Gell, D.4
Xiang, X.H.5
Torres Arzayus, M.I.6
Priestley, A.7
Jackson, S.P.8
Rothstein, A.M.9
Jeggo, P.A.10
Herrera, V.L.M.11
-
97
-
-
0020534965
-
Somatic generation of antibody diversity
-
(1983)
Nature
, vol.302
, pp. 575-581
-
-
Tonegawa, S.1
-
98
-
-
0023882920
-
In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes
-
(1988)
Cell
, vol.52
, pp. 831-841
-
-
Uematsu, Y.1
Ryser, S.2
Dembic, Z.3
Borulya, P.4
Krimpenfort, P.5
Berns, A.6
Von Boehmer, H.7
Steinmetz, M.8
-
101
-
-
0032577548
-
Partial V(D)J recombination activity leads to Omenn syndrome
-
(1998)
Cell
, vol.93
, pp. 885-896
-
-
Villa, A.1
Santagata, S.2
Bozzi, F.3
Giliani, S.4
Frattini, A.5
Imberti, L.6
Gatta, L.B.7
Ochs, H.D.8
Schwarz, K.9
Notarangelo, L.D.10
-
107
-
-
0033549813
-
Continued RAG expression in late stages of B cell development and no apparent re-induction after immunization
-
(1999)
Nature
, vol.400
, pp. 682-687
-
-
Yu, W.1
Nagaoka, H.2
Jankovic, M.3
Misulovin, Z.4
Suh, H.5
Melchers, F.6
Meffre, E.7
Nussenzweig, M.C.8
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