Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA

Molecular Cell

Volumn 6, Issue 5, 2000, Pages 1037-1048

  Kwon, Jongbum ^a,b   Morshead, Katrina B ^a,b   Guyon, Jeffrey R ^a,b   Kingston, Robert E ^a,b   Oettinger, Marjorie A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HISTONE ACETYLTRANSFERASE;

ACETYLATION; ARTICLE; CELL NUCLEUS; DNA CLEAVAGE; GENE; GENE EXPRESSION; GENETIC RECOMBINATION; HELA CELL; HUMAN; HUMAN CELL; LYMPHOID CELL; NUCLEOSOME;

EID: 0033638506     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)00102-7     Document Type: Article

References (39)

1. Efficient large-scale purification of non-histone chromosomal proteins HMG1 and HMG2 by using Polybuffer-exchanger PBE94
2. The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2
3. Histone hyperacetylation: Its effects on nucleosome conformation and stability
4. Chromatin remodeling directly activates V(D)J recombination
5. Basic analysis of transcription factor binding to nucleosomes
6. Recent advances in understanding V(D)J recombination
7. Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase
8. Histone acetylation in chromatin structure and transcription
9. Stable remodeling of tailless nucleosomes by the human SWI-SNF complex
10. Facilitated binding of TATA-binding protein to nucleosomal DNA
11. Nucleosome disruption by human SWI/SNF is maintained in the absence of continued ATP hydrolysis
12. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity
13. Dual role of RAG2 in V(D)J recombination: Catalysis and regulation of ordered Ig gene assembly
14. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
15. Nucleosome disruption and enhancement of activator binding by a human SWI/SNF complex
16. Accessibility of nucleosomal DNA to V(D)J cleavage of nucleosomal DNA is modulated by RSS positioning and HMG1
17. The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
18. Histone octamer transfer by a chromatin-remodeling complex
19. Stimulation of V(D)J recombination by histone acetylation
20. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
21. A role for histone acetylation in the development regulation of V(D)J recombination
22. Regulation of RAG expression in developing lymphocytes
23. V(D)J recombination: On the cutting edge
24. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
25. Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits
26. Ocatmer transfer and creation of stably remodeled nucleosomes by human SWI/SNF and its isolated ATPases
27. E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells
28. V(D)J recombination: Modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins
29. The V(D)J recombination activating gene (RAG-1)
30. Accessibility and the developmental regulation of V(D)J recombination
31. Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state
32. Mitotic inactivation of a human SWI/SNF chromatin remodeling complex
33. Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements
34. Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
35. Histone acetylation and transcriptional regulatory mechanisms
36. Stimulation of V(D)J cleavage by high mobility group proteins
37. ATP-dependent chromatin-remodeling complexes
38. Review: Chromatin structural features and targets that regulate transcription
39. Alteration of nucleosome structure as a mechanism of transcriptional regulation