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Volumn 186, Issue 6, 1997, Pages 921-929

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination in vivo

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN SUBUNIT; T LYMPHOCYTE RECEPTOR;

EID: 0030885974     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.6.921     Document Type: Article
Times cited : (242)

References (36)
  • 1
    • 0029585872 scopus 로고
    • The XRCC4 gene encodes a novel protein involved in DNa double-strand break repair and V(D)J recombination
    • Li, Z., T. Otevrel, Y. Gao, H.-L. Cheng, B. Sneed, T. Stamato, G. Taccioli, and F.W. Alt. 1995. The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell. 83:1079-1089.
    • (1995) Cell , vol.83 , pp. 1079-1089
    • Li, Z.1    Otevrel, T.2    Gao, Y.3    Cheng, H.-L.4    Sneed, B.5    Stamato, T.6    Taccioli, G.7    Alt, F.W.8
  • 3
    • 0027245559 scopus 로고
    • V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair
    • Pergola, F., M.Z. Zdzienicka, and M.R. Lieber. 1993. V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair. Mol. Cell. Biol. 13:3464-3471.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3464-3471
    • Pergola, F.1    Zdzienicka, M.Z.2    Lieber, M.R.3
  • 6
    • 0029886929 scopus 로고    scopus 로고
    • Mechanism of V(D)J recombination
    • Bogue, M., and D.B. Roth. 1996. Mechanism of V(D)J recombination. Curr. Opin. Immunology. 8:175-180.
    • (1996) Curr. Opin. Immunology , vol.8 , pp. 175-180
    • Bogue, M.1    Roth, D.B.2
  • 7
    • 0029395076 scopus 로고
    • Menage a trois: Double strand break repair, V(D)J recombination and DNA-PK
    • Jeggo, P.A., G.A. Taccioli, and S.P. Jackson. 1995. Menage a trois: double strand break repair, V(D)J recombination and DNA-PK. Biocssays. 17:949-956.
    • (1995) Biocssays , vol.17 , pp. 949-956
    • Jeggo, P.A.1    Taccioli, G.A.2    Jackson, S.P.3
  • 8
    • 0029117310 scopus 로고
    • What to do at an end: DNA doublestrand-break repair
    • Weaver, D.T. 1995. What to do at an end: DNA doublestrand-break repair. TIG (Trends Genet.) 11:388-392.
    • (1995) TIG (Trends Genet.) , vol.11 , pp. 388-392
    • Weaver, D.T.1
  • 9
    • 0026071588 scopus 로고
    • Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNa double-strand break repair
    • Biedermann, K.A., J. Sun, A.J. Giaccia, L.M. Tosto, and J.M. Brown. 1991. scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl. Acad. Sci. USA. 88:1394-1397.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1394-1397
    • Biedermann, K.A.1    Sun, J.2    Giaccia, A.J.3    Tosto, L.M.4    Brown, J.M.5
  • 10
    • 0027048773 scopus 로고
    • Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNa polymerase II
    • Dvir, A., S.R. Peterson, M.W. Knuth, H. Lu, and W.S. Dynan. 1992. Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. Proc. Natl. Acad. Sci. USA. 89:11920-11924.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11920-11924
    • Dvir, A.1    Peterson, S.R.2    Knuth, M.W.3    Lu, H.4    Dynan, W.S.5
  • 11
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
    • Gottlieb, T.M., and S.P. Jackson. 1993. The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell. 72:131-142.
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 12
    • 0030339852 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight
    • Lees-Miller, S.P. 1996. The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight. Biochem. Cell Biol. 74:503-512.
    • (1996) Biochem. Cell Biol. , vol.74 , pp. 503-512
    • Lees-Miller, S.P.1
  • 13
    • 0028902932 scopus 로고
    • Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
    • Peterson, S.R., A. Kunmasa. M, Oshimura, W.S. Dynan, E.M. Bradbury, and D.J. Chen. 1995. Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA. 92:3171-3174.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3171-3174
    • Peterson, S.R.1    Kunmasa, A.2    Oshimura, M.3    Dynan, W.S.4    Bradbury, E.M.5    Chen, D.J.6
  • 17
    • 0028112944 scopus 로고
    • Restoration of x-ray resistance and V(D)J recombination in mutant cells by Ku cDNA
    • Smider, V., W.K. Rathmell, M.R. Lieber, and G. Chu. 1994. Restoration of x-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science (Wash. DC). 266: 288-291.
    • (1994) Science (Wash. DC) , vol.266 , pp. 288-291
    • Smider, V.1    Rathmell, W.K.2    Lieber, M.R.3    Chu, G.4
  • 20
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and detective processing of V(D)J recombination intermediates
    • Zhu, C., M.A. Bogue, D.-S. Lim, P. Hasty, and D.B. Roth. 1996. Ku86-deficient mice exhibit severe combined immunodeficiency and detective processing of V(D)J recombination intermediates. Cell. 86:379-389.
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5
  • 22
    • 0029009013 scopus 로고
    • A constitutive heat shock element-binding factor is immunologically identical to the Ku-autoantigen
    • Kim, D., H. Ouyang, S.-H. Yang, A. Nussenzweig, P. Burgman, and G.G. Li. 1995. A constitutive heat shock element-binding factor is immunologically identical to the Ku-autoantigen. J. Biol. Chem. 270: 15277-15284.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15277-15284
    • Kim, D.1    Ouyang, H.2    Yang, S.-H.3    Nussenzweig, A.4    Burgman, P.5    Li, G.G.6
  • 24
    • 0028276571 scopus 로고
    • Expression of the retinoblastoma protein is regulated in normal human tissue
    • Cordon-Cardo, C., and V.M. Richon. 1994. Expression of the retinoblastoma protein is regulated in normal human tissue. Am. J. Pathol. 144:500-510.
    • (1994) Am. J. Pathol. , vol.144 , pp. 500-510
    • Cordon-Cardo, C.1    Richon, V.M.2
  • 26
    • 0026534145 scopus 로고
    • Chromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice
    • Costa, T.E.F., H. Suh, and M. Nussenzweig. 1992. Chromosomal position of rearranging gene segments influences allelic exclusion in transgenic mice. Proc. Natl. Acad. Sci. USA. 89: 2205-2208.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2205-2208
    • Costa, T.E.F.1    Suh, H.2    Nussenzweig, M.3
  • 27
    • 0027491330 scopus 로고
    • Characterization of broken DNA molecules associated with V(D)J recombination
    • Roth, D.B., C. Zhu, and M. Gellert. 1993. Characterization of broken DNA molecules associated with V(D)J recombination. Proc. Natl. Acad. Sci. USA. 90:10788-10792.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10788-10792
    • Roth, D.B.1    Zhu, C.2    Gellert, M.3
  • 28
    • 0029881698 scopus 로고    scopus 로고
    • p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes
    • Bogue, M.A., C. Zhu, E. Aguilar-Cordova, L.A. Donehower, and D.B. Roth. 1996. p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes. Genes Dev. 10:553-565.
    • (1996) Genes Dev. , vol.10 , pp. 553-565
    • Bogue, M.A.1    Zhu, C.2    Aguilar-Cordova, E.3    Donehower, L.A.4    Roth, D.B.5
  • 29
    • 0020555696 scopus 로고
    • The effect of hyperthermia on hemopoietic progenitor cells of the mouse
    • Van Zant, G., D. Flentje, and M. Flentje. 1983. The effect of hyperthermia on hemopoietic progenitor cells of the mouse. Radiat. Res. 95:142-149.
    • (1983) Radiat. Res. , vol.95 , pp. 142-149
    • Van Zant, G.1    Flentje, D.2    Flentje, M.3
  • 30
    • 0022002159 scopus 로고
    • Thermotolerance and profile of protein synthesis in murine bone marrow cells after heat shock
    • Mivechi, N.F., and G.C. Li. 1985. Thermotolerance and profile of protein synthesis in murine bone marrow cells after heat shock. Cancer Res. 45:3843-3849.
    • (1985) Cancer Res. , vol.45 , pp. 3843-3849
    • Mivechi, N.F.1    Li, G.C.2
  • 31
    • 0025980247 scopus 로고
    • Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis
    • Illiakis, G., L. Metzger, N. Denko, and T.D. Stamato. 1991. Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. Int. J. Radiat. Biol. 59:321-341.
    • (1991) Int. J. Radiat. Biol. , vol.59 , pp. 321-341
    • Illiakis, G.1    Metzger, L.2    Denko, N.3    Stamato, T.D.4
  • 32
    • 0025011134 scopus 로고
    • The scid mutation in mice causes a general defect in DNa repair
    • Fulop, G.M., and R.A. Phillips. 1990. The scid mutation in mice causes a general defect in DNA repair. Nature (Lond.). 347:479-482.
    • (1990) Nature (Lond.) , vol.347 , pp. 479-482
    • Fulop, G.M.1    Phillips, R.A.2
  • 33
    • 0028297141 scopus 로고
    • Bcl-2 expression promotes B- But not T-lymphoid development in scid mice
    • Strasser, A., A.W. Harris, L.M. Corcoran, and S. Cory. 1994. Bcl-2 expression promotes B-but not T-lymphoid development in scid mice. Nature (Lond.). 368:457-460.
    • (1994) Nature (Lond.) , vol.368 , pp. 457-460
    • Strasser, A.1    Harris, A.W.2    Corcoran, L.M.3    Cory, S.4
  • 35
    • 15844385545 scopus 로고    scopus 로고
    • Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA
    • Liang, F., and M. Jasin. 1996. Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA. J. Biol. Chem. 271:14405-14411.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14405-14411
    • Liang, F.1    Jasin, M.2
  • 36
    • 0026571874 scopus 로고
    • Role of a major autoepitope in forming the DNa binding site of the p70 (Ku) antigen
    • Chou, C.H., J. Wang, M.W. Knuth, and W.H. Reeves. 1992. Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen. J. Exp. Med 175:1677-1684.
    • (1992) J. Exp. Med , vol.175 , pp. 1677-1684
    • Chou, C.H.1    Wang, J.2    Knuth, M.W.3    Reeves, W.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.