-
1
-
-
0032551829
-
Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system
-
Agrawal, A., Q.M. Eastman, and D.G. Schatz. 1998. Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system. Nature 394: 744-751.
-
(1998)
Nature
, vol.394
, pp. 744-751
-
-
Agrawal, A.1
Eastman, Q.M.2
Schatz, D.G.3
-
2
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin, S., L. Moyal, S. Shieh, Y. Taya, C.W. Anderson, L. Chessa, N.I. Smorodinsky, C. Prives, Y. Reiss, Y. Shiloh, and Y. Ziv. 1998. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281: 1674-1677.
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
3
-
-
15844426692
-
Atm-deficient mice: A paradigm of Ataxia Telangiectasia
-
Barlow, C., S. Hirotsune, R. Paylor, M. Liyanage, M. Eckhaus, F. Collins, Y. Shiloh, J.N. Crawley, T. Ried, D. Tagle, and A. Wynshaw-Boris. 1996. Atm-deficient mice: A paradigm of Ataxia Telangiectasia. Cell 86: 159-171.
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
Liyanage, M.4
Eckhaus, M.5
Collins, F.6
Shiloh, Y.7
Crawley, J.N.8
Ried, T.9
Tagle, D.10
Wynshaw-Boris, A.11
-
4
-
-
0030667522
-
Atm selectively regulates distince p53-dependent cell-cycle checkpoint and apoptotic pathways
-
Barlow, C., K. Brown, C. Deng, D. Tagle, and A. Wynshaw-Boris. 1997. Atm selectively regulates distince p53-dependent cell-cycle checkpoint and apoptotic pathways. Nat. Genet. 17: 453-456.
-
(1997)
Nat. Genet.
, vol.17
, pp. 453-456
-
-
Barlow, C.1
Brown, K.2
Deng, C.3
Tagle, D.4
Wynshaw-Boris, A.5
-
5
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman, C.E., D.S. Lim, K.A. Cimprich, Y. Taya, K. Tamai, K. Sakaguchi, E. Appella, M.B. Kastan, and J.D. Siliciano. 1998. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281: 1677-1679.
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
6
-
-
0031170827
-
Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors
-
Danska, J.S. and C.J. Guidos. 1997. Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors. Semin. Immunol. 9: 199-206.
-
(1997)
Semin. Immunol.
, vol.9
, pp. 199-206
-
-
Danska, J.S.1
Guidos, C.J.2
-
7
-
-
0029808466
-
Cell cycle checkpoints: Preventing an identity crisis
-
Elledge, S.J. 1996. Cell cycle checkpoints: Preventing an identity crisis. Science 274: 1664-1672.
-
(1996)
Science
, vol.274
, pp. 1664-1672
-
-
Elledge, S.J.1
-
8
-
-
0029848286
-
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice
-
Elson, A., Y. Wang, C. Daugherty, C. Morton, F. Zhou, J. Campos-Torres, and P. Leder. 1996. Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc. Natl. Acad. Sci. 93: 13084-13089.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 13084-13089
-
-
Elson, A.1
Wang, Y.2
Daugherty, C.3
Morton, C.4
Zhou, F.5
Campos-Torres, J.6
Leder, P.7
-
9
-
-
0032524070
-
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
-
Herzog, K.H., M.J. Chong, M. Kapsetaki, J.I. Morgan, and P.J. McKinnon. 1998. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 280: 1089-1091.
-
(1998)
Science
, vol.280
, pp. 1089-1091
-
-
Herzog, K.H.1
Chong, M.J.2
Kapsetaki, M.3
Morgan, J.I.4
McKinnon, P.J.5
-
10
-
-
0032555758
-
DNA transposition by the RAG1 and RAG2 proteins: A possible source of oncogenic translocations
-
Hiom, K., M. Melek, and M. Gellert. 1998. DNA transposition by the RAG1 and RAG2 proteins: A possible source of oncogenic translocations. Cell 94: 463-470.
-
(1998)
Cell
, vol.94
, pp. 463-470
-
-
Hiom, K.1
Melek, M.2
Gellert, M.3
-
11
-
-
0032404350
-
Splitting the ATM: Distinct repair and checkpoint defects in ataxia-telangiectasia
-
Jeggo, P.A., A.M. Carr, and A.R. Lehmann. 1998. Splitting the ATM: Distinct repair and checkpoint defects in ataxia-telangiectasia. Trends Genet. 14: 312-316.
-
(1998)
Trends Genet.
, vol.14
, pp. 312-316
-
-
Jeggo, P.A.1
Carr, A.M.2
Lehmann, A.R.3
-
12
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in Ataxia-telangiectasia
-
Kastan, M.B., Q. Zhan, W.S. El-Deiry, F. Carrier, T. Jacks, W. V. Walsh, B.S. Plunkett, B. Vogelstein, and A.J. Fornace, Jr. 1992. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in Ataxia-Telangiectasia. Cell 71: 587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace A.J., Jr.9
-
13
-
-
0028588644
-
V(D)J recombination and ataxia-telangiectasia: A review
-
Kirsch, I.R. 1994. V(D)J recombination and ataxia-telangiectasia: A review. Int. J. Radiat. Biol. 66: S97-S108.
-
(1994)
Int. J. Radiat. Biol.
, vol.66
-
-
Kirsch, I.R.1
-
14
-
-
0031170828
-
Lymphocyte-specific genomic instability and risk of lymphoid malignancy
-
Kirsch, I.R. and F. Lista. 1997. Lymphocyte-specific genomic instability and risk of lymphoid malignancy. Semin. Immunol. 9: 207-215.
-
(1997)
Semin. Immunol.
, vol.9
, pp. 207-215
-
-
Kirsch, I.R.1
Lista, F.2
-
15
-
-
0025954329
-
Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia
-
Kobayashi, Y., B. Tycko, A.L. Soreng, and J. Sklar. 1991. Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia J. Immunol. 147: 3201-3209.
-
(1991)
J. Immunol.
, vol.147
, pp. 3201-3209
-
-
Kobayashi, Y.1
Tycko, B.2
Soreng, A.L.3
Sklar, J.4
-
16
-
-
0030933152
-
The genetic defect in ataxia-telangiectasia
-
Lavin, M.F. and Y. Shiloh. 1997. The genetic defect in ataxia-telangiectasia. Annu. Rev. Immunol. 15: 177-202.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 177-202
-
-
Lavin, M.F.1
Shiloh, Y.2
-
17
-
-
0028048275
-
The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
-
Lewis, S.M. 1994. The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses. Adv. Immunol. 56: 27-150.
-
(1994)
Adv. Immunol.
, vol.56
, pp. 27-150
-
-
Lewis, S.M.1
-
18
-
-
0031869669
-
No requirement for V(D)J recombination in p53-deficient thymic lymphoma
-
Liao, M.-J., X. Zhang, R. Hill, J. Gao, M. Qumsiyeh, W. Nichols, and T. Van Dyke. 1998. No requirement for V(D)J recombination in p53-deficient thymic lymphoma. Mol. Cell. Biol. 18: 3495-3501.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3495-3501
-
-
Liao, M.-J.1
Zhang, X.2
Hill, R.3
Gao, J.4
Qumsiyeh, M.5
Nichols, W.6
Van Dyke, T.7
-
19
-
-
0024987973
-
Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes
-
Lipkowitz, S., M.H. Stern, and I.R. Kirsch. 1990. Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes J. Exp. Med. 172: 409-418.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 409-418
-
-
Lipkowitz, S.1
Stern, M.H.2
Kirsch, I.R.3
-
20
-
-
0028805853
-
Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
-
McBlane, J.F., D.C. van Gent, D.A. Ramsden, C. Romeo, C.A. Cuomo, M. Gellert, and M.A. Oettinger. 1995. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell 83: 387-395.
-
(1995)
Cell
, vol.83
, pp. 387-395
-
-
McBlane, J.F.1
Van Gent, D.C.2
Ramsden, D.A.3
Romeo, C.4
Cuomo, C.A.5
Gellert, M.6
Oettinger, M.A.7
-
21
-
-
0028880649
-
Ataxia-telangiectasia and cellular responses to DNA damage
-
Meyn, M.S. 1995. Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Res. 55: 5991-6001.
-
(1995)
Cancer Res.
, vol.55
, pp. 5991-6001
-
-
Meyn, M.S.1
-
22
-
-
0026585781
-
RAG-1-deficient mice have no mature B and T lymphocytes
-
Mombaerts, P., J. Iacomini, R.S. Johnson, K. Herrup, S. Tonegawa, and V. Papaioannou. 1992. RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68: 869-877.
-
(1992)
Cell
, vol.68
, pp. 869-877
-
-
Mombaerts, P.1
Iacomini, J.2
Johnson, R.S.3
Herrup, K.4
Tonegawa, S.5
Papaioannou, V.6
-
23
-
-
0031992186
-
V(D)J recombination is not required for the development of lymphoma in p53-deficient mice
-
Nacht, M. and T. Jacks. 1998. V(D)J recombination is not required for the development of lymphoma in p53-deficient mice. Cell Growth Differ. 9: 131-138.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 131-138
-
-
Nacht, M.1
Jacks, T.2
-
24
-
-
0030901160
-
Genetic alterations in leukemias and lymphomas: Impressive progress and continuing complexity
-
Nowell, P.C. 1997. Genetic alterations in leukemias and lymphomas: Impressive progress and continuing complexity. Cancer Genet. Cytogenet. 94: 13-19.
-
(1997)
Cancer Genet. Cytogenet.
, vol.94
, pp. 13-19
-
-
Nowell, P.C.1
-
25
-
-
0026663777
-
Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells
-
Pandita, T.K. and W.N. Hittelman. 1992. Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells. Radiat. Res. 130: 94-103.
-
(1992)
Radiat. Res.
, vol.130
, pp. 94-103
-
-
Pandita, T.K.1
Hittelman, W.N.2
-
27
-
-
0024307348
-
Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
-
Pircher, H., K. Burki, R. Lang, H. Hengartner, and R.M. Zinkernagel. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342: 559-561.
-
(1989)
Nature
, vol.342
, pp. 559-561
-
-
Pircher, H.1
Burki, K.2
Lang, R.3
Hengartner, H.4
Zinkernagel, R.M.5
-
28
-
-
0030724981
-
ATM and RPA in meiotic chromosome synapsis and recombination
-
Plug, A., A. Peters, Y. Xu, K. Keegan, M. Hoekstra, D. Baltimore, P. de Boer, and T. Ashley. 1997. ATM and RPA in meiotic chromosome synapsis and recombination. Nat. Genet. 17: 457-461.
-
(1997)
Nat. Genet.
, vol.17
, pp. 457-461
-
-
Plug, A.1
Peters, A.2
Xu, Y.3
Keegan, K.4
Hoekstra, M.5
Baltimore, D.6
De Boer, P.7
Ashley, T.8
-
29
-
-
0027970838
-
Chromosomal translocations in human cancer
-
Rabbitts, T.H. 1994. Chromosomal translocations in human cancer. Nature 372: 143-149.
-
(1994)
Nature
, vol.372
, pp. 143-149
-
-
Rabbitts, T.H.1
-
30
-
-
0029820057
-
Ataxia-telangiectasia and the ATM gene: Linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints
-
Shiloh, Y. and G. Rotman. 1996. Ataxia-telangiectasia and the ATM gene: linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints J. Clin. Immunol. 16: 154-260.
-
(1996)
J. Clin. Immunol.
, vol.16
, pp. 154-260
-
-
Shiloh, Y.1
Rotman, G.2
-
31
-
-
0026581936
-
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
-
Shinkai, Y., G. Rathbun, K. Lam, E. Oltz, V. Stewart, M. Mendelsohn, J. Charron, M. Datta, F. Young, A. Stall, and F. Alt. 1992. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68: 855-867.
-
(1992)
Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.3
Oltz, E.4
Stewart, V.5
Mendelsohn, M.6
Charron, J.7
Datta, M.8
Young, F.9
Stall, A.10
Alt, F.11
-
32
-
-
0027406812
-
Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes
-
Shinkai, Y., S. Koyasu, K. Nakayama, K. Murphy, D. Loh, E. Reinherz, and F. Alt. 1993. Restoration of T cell development in RAG-1-deficient mice by functional TCR transgenes. Science 259: 822-825.
-
(1993)
Science
, vol.259
, pp. 822-825
-
-
Shinkai, Y.1
Koyasu, S.2
Nakayama, K.3
Murphy, K.4
Loh, D.5
Reinherz, E.6
Alt, F.7
-
33
-
-
0030051855
-
Leukemia and lymphoma in ataxia telangiectasia
-
Taylor, A.M.R., J.A. Metcalfe, J. Thick, and Y.-F. Mak. 1996. Leukemia and lymphoma in ataxia telangiectasia. Blood 87: 423-438.
-
(1996)
Blood
, vol.87
, pp. 423-438
-
-
Taylor, A.M.R.1
Metcalfe, J.A.2
Thick, J.3
Mak, Y.-F.4
-
34
-
-
0030879563
-
Atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity
-
Westphal, C., S. Rowan, C. Schmaltz, A. Elson, D. Fisher, and P. Leder. 1997. atm and p53 cooperate in apoptosis and suppression of tumorigenesis, but not in resistance to acute radiation toxicity. Nat. Genet. 16: 397-401.
-
(1997)
Nat. Genet.
, vol.16
, pp. 397-401
-
-
Westphal, C.1
Rowan, S.2
Schmaltz, C.3
Elson, A.4
Fisher, D.5
Leder, P.6
-
35
-
-
0029821651
-
Dual roles of ATM in the cellular response to radiation and in cell growth control
-
Xu, Y. and D. Baltimore. 1996. Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes & Dev. 10: 2401-2410.
-
(1996)
Genes & Dev.
, vol.10
, pp. 2401-2410
-
-
Xu, Y.1
Baltimore, D.2
-
36
-
-
0029844048
-
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
-
Xu, Y., T. Ashley, E.E. Brainerd, R.T. Bronson, M.S. Meyn, and D. Baltimore. 1996. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes & Dev. 10: 2411-2422.
-
(1996)
Genes & Dev.
, vol.10
, pp. 2411-2422
-
-
Xu, Y.1
Ashley, T.2
Brainerd, E.E.3
Bronson, R.T.4
Meyn, M.S.5
Baltimore, D.6
|