DNA repair: How Ku makes ends meet

Current Biology

Volumn 11, Issue 22, 2001, Pages

  Doherty, Aidan J ^a   Jackson, Stephen P ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0035856495     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00555-3     Document Type: Review

References (24)

1. DNA end-joining: From yeast to man
2. The DNA-dependent protein kinase
3. Ku, a DNA repair protein with multiple cellular functions?
4. Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
5. Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids
6. Ku recruits the XRCC4-ligase IV complex to DNA ends
7. Lif1p targets the DNA ligase Lig4p to sites of DNA double-strand breaks
8. The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities
9. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
10. Mapping of protein-protein interactions within the DNA-dependent protein kinase complex
11. Evolution of domain families
12. Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86
13. Identification of two domains of the p70 Ku protein mediating dimerization with p80 and DNA binding
14. Defining functional domains of Ku80: DNA end binding and survival after radiation
15. Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex
16. Photocross-linking of an oriented DNA repair complex - Ku bound at a single DNA end
17. Ku selectively transfers between DNA molecules with homologous ends
18. The many interfaces of Mre11
19. Defining the minimal domain of Ku80 for interaction with Ku70
20. The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70
21. Identification of bacterial homologues of the Ku DNA repair proteins
22. Prokaryotic homologs of the eukaryotic DNA-end-binding protein ku, novel domains in the ku protein and prediction of a prokaryotic double-strand break repair system
23. Telomeric localization of TRF2, a novel human telobox protein
24. A short C-terminal domain of Yku70p is essential for telomere maintenance