Gene-targeted deletion and replacement mutations of the T-cell receptor β-chain enhancer: The role of enhancer elements in controlling V(D)J recombination accessibility

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 15, 1996, Pages 7871-7876

  Bories, Jean Christophe ^a,b   Demengeot, Jocelyne ^b,d   Davidson, Laurie ^b,c   Alt, Frederick W ^b,c  

^a SAINT LOUIS HOSPITAL   (France)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d Unité d'Immunobiologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN J CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHIMERA; CONTROLLED STUDY; EMBRYO CELL; ENHANCER REGION; GENE DELETION; GENE LOCUS; GENE MUTATION; GENE REARRANGEMENT; GENE TARGETING; GENETIC RECOMBINATION; IMMUNOGLOBULIN VARIABLE REGION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ALLELES; ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; BLASTOCYST; CELLS, CULTURED; CHIMERA; DNA NUCLEOTIDYLTRANSFERASES; DNA PRIMERS; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE DELETION; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; GENETIC COMPLEMENTATION TEST; GENOMIC LIBRARY; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN JOINING REGION; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PROTEINS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RESTRICTION MAPPING; SEQUENCE DELETION; SPLEEN; STEM CELLS; TRANSCRIPTION, GENETIC; VDJ RECOMBINASES;

ANIMALIA;

EID: 0029819322     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.15.7871     Document Type: Article

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