-
3
-
-
0031433563
-
Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor β locus
-
Aifantis, I., Buer, J., von Boehmer, H., and Azogui, O. (1997). Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor β locus. Immunity 7, 601-607. Erratum:
-
(1997)
Immunity
, vol.7
, pp. 601-607
-
-
Aifantis, I.1
Buer, J.2
Von Boehmer, H.3
Azogui, O.4
-
4
-
-
0013618909
-
-
Immunity 7(6), 1997.
-
(1997)
Immunity
, vol.7
, Issue.6
-
-
-
5
-
-
0028859281
-
Selective requirement for MAP kinase activation in thymocyte differentiation
-
Alberola-Ila, J., Forbush, K.A., Seger, R., Krebs, E.G., and Perlmutter, R.M. (1995). Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373, 620-623.
-
(1995)
Nature
, vol.373
, pp. 620-623
-
-
Alberola-Ila, J.1
Forbush, K.A.2
Seger, R.3
Krebs, E.G.4
Perlmutter, R.M.5
-
8
-
-
0030043836
-
Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB
-
Barton, K., Muthusamy, N., Chanyangam, M., Fischer, C., Clendenin, C., and Leiden, J.M. (1996). Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature 379, 81-85.
-
(1996)
Nature
, vol.379
, pp. 81-85
-
-
Barton, K.1
Muthusamy, N.2
Chanyangam, M.3
Fischer, C.4
Clendenin, C.5
Leiden, J.M.6
-
9
-
-
0032191918
-
The Ets-1 transcription factor is required for the development of natural killer cells in mice
-
Barton, K., Muthusamy, N., Fischer, C., Ting, C.N., Walunas, T.L., Lanier, L.L., and Leiden, J.M. (1998). The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity 9, 555-563.
-
(1998)
Immunity
, vol.9
, pp. 555-563
-
-
Barton, K.1
Muthusamy, N.2
Fischer, C.3
Ting, C.N.4
Walunas, T.L.5
Lanier, L.L.6
Leiden, J.M.7
-
10
-
-
0028880729
-
Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene
-
Bories, J.C., Willerford, D.M., Grevin, D., Davidson, L., Camus, A., Martin, P., Stehelin, D., and Alt, F.W. (1995). Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene. Nature 377, 635-638.
-
(1995)
Nature
, vol.377
, pp. 635-638
-
-
Bories, J.C.1
Willerford, D.M.2
Grevin, D.3
Davidson, L.4
Camus, A.5
Martin, P.6
Stehelin, D.7
Alt, F.W.8
-
11
-
-
0029931057
-
A role for c-myc in the regulation of thymocyte differentiation and possibly positive selection
-
Broussard-Diehl, C., Bauer, S.R., and Scheuermann, R.H. (1996). A role for c-myc in the regulation of thymocyte differentiation and possibly positive selection. J. Immunol. 156, 3141-3150.
-
(1996)
J. Immunol.
, vol.156
, pp. 3141-3150
-
-
Broussard-Diehl, C.1
Bauer, S.R.2
Scheuermann, R.H.3
-
12
-
-
0029071585
-
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function
-
Chan, A.C., Dalton, M., Johnson, R., Kong, G.H., Wang, T., Thoma, R., and Kurosaki, T. (1995). Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14, 2499-2508.
-
(1995)
EMBO J.
, vol.14
, pp. 2499-2508
-
-
Chan, A.C.1
Dalton, M.2
Johnson, R.3
Kong, G.H.4
Wang, T.5
Thoma, R.6
Kurosaki, T.7
-
13
-
-
0030740148
-
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
-
Chan, V.W., Meng, F., Soriano, P., DeFranco, A.L., and Lowell, C.A. (1997). Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation. Immunity 7, 69-81.
-
(1997)
Immunity
, vol.7
, pp. 69-81
-
-
Chan, V.W.1
Meng, F.2
Soriano, P.3
DeFranco, A.L.4
Lowell, C.A.5
-
14
-
-
0027956217
-
IL-2 receptor α chain expression during early B lymphocyte differentiation
-
Chen, J., Ma, A., Young, F., and Alt, F.W. (1994). IL-2 receptor α chain expression during early B lymphocyte differentiation. Int. Immunol. 6, 1265-1268.
-
(1994)
Int. Immunol.
, vol.6
, pp. 1265-1268
-
-
Chen, J.1
Ma, A.2
Young, F.3
Alt, F.W.4
-
15
-
-
0028783322
-
Syk tyrosine kinase required for mouse viability and B-cell development
-
Cheng, A.M., Rowley, B., Pao, W., Hayday, A., Bolen, J.B., and Pawson, T. (1995). Syk tyrosine kinase required for mouse viability and B-cell development. Nature 378, 303-306.
-
(1995)
Nature
, vol.378
, pp. 303-306
-
-
Cheng, A.M.1
Rowley, B.2
Pao, W.3
Hayday, A.4
Bolen, J.B.5
Pawson, T.6
-
16
-
-
0030886836
-
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
-
Cheng, A.M., Negishi, I., Andersen, S.J., Chan, A.C., Bolen, J., Loh, D.Y., and Pawson, T. (1997). The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. Proc. Natl. Acad. Sci. USA 94, 9797-9801.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9797-9801
-
-
Cheng, A.M.1
Negishi, I.2
Andersen, S.J.3
Chan, A.C.4
Bolen, J.5
Loh, D.Y.6
Pawson, T.7
-
17
-
-
0031788487
-
The Syk family of protein tyrosine kinases in T-cell activation and development
-
Chu, D.H., Morita, C.T., and Weiss, A. (1998). The Syk family of protein tyrosine kinases in T-cell activation and development. Immunol. Rev. 165, 167-180.
-
(1998)
Immunol. Rev.
, vol.165
, pp. 167-180
-
-
Chu, D.H.1
Morita, C.T.2
Weiss, A.3
-
18
-
-
0032540906
-
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
-
Clements, J.L., Yang, B., Ross-Barta, S.E., Eliason, S.L., Hrstka, R.F., Williamson, R.A., and Koretzky, G.A. (1998). Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 281, 416-419.
-
(1998)
Science
, vol.281
, pp. 416-419
-
-
Clements, J.L.1
Yang, B.2
Ross-Barta, S.E.3
Eliason, S.L.4
Hrstka, R.F.5
Williamson, R.A.6
Koretzky, G.A.7
-
19
-
-
0030602798
-
The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte
-
Crompton, T., Gilmour, K.C., and Owen, M.J. (1996). The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86, 243-251.
-
(1996)
Cell
, vol.86
, pp. 243-251
-
-
Crompton, T.1
Gilmour, K.C.2
Owen, M.J.3
-
20
-
-
0030391327
-
The cell cycle and V(D)J recombination
-
Desiderio, S., Lin, W.C., and Li, Z. (1996). The cell cycle and V(D)J recombination. Curr. Top. Microbiol. Immunol. 217, 45-59.
-
(1996)
Curr. Top. Microbiol. Immunol.
, vol.217
, pp. 45-59
-
-
Desiderio, S.1
Lin, W.C.2
Li, Z.3
-
21
-
-
0032080849
-
Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy
-
DeSilva, D.R., Jones, E.A., Favata, M.F., Jaffee, B.D., Magolda, R.L., Trzaskos, J.M., and Scherle, P.A. (1998). Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy. J. Immunol. 160, 4175-4181.
-
(1998)
J. Immunol.
, vol.160
, pp. 4175-4181
-
-
DeSilva, D.R.1
Jones, E.A.2
Favata, M.F.3
Jaffee, B.D.4
Magolda, R.L.5
Trzaskos, J.M.6
Scherle, P.A.7
-
22
-
-
0032546737
-
Signal transduction pathways regulating the development of αβ T cells
-
Farrar, M.A., Doerfler, P., and Sauer, K. (1998). Signal transduction pathways regulating the development of αβ T cells. Biochim. Biophys. Acta 1377, F35-F78.
-
(1998)
Biochim. Biophys. Acta
, vol.1377
-
-
Farrar, M.A.1
Doerfler, P.2
Sauer, K.3
-
23
-
-
0025630236
-
A cell cycle analysis of growth-related genes expressed during T lymphocyte maturation
-
Feder, J.N., Guidos, C.J., Kusler, B., Carswell, C., Lewis, D., and Schimke, R.T. (1990). A cell cycle analysis of growth-related genes expressed during T lymphocyte maturation. J. Cell Biol. 111, 2693-2701.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 2693-2701
-
-
Feder, J.N.1
Guidos, C.J.2
Kusler, B.3
Carswell, C.4
Lewis, D.5
Schimke, R.T.6
-
24
-
-
0030847208
-
-/- mice by anti-CD3∈ antibody treatment or with transgenes encoding activated Lck or tailless pTα
-
-/- mice by anti-CD3∈ antibody treatment or with transgenes encoding activated Lck or tailless pTα. Immunity 6, 703-714.
-
(1997)
Immunity
, vol.6
, pp. 703-714
-
-
Fehling, H.J.1
Iritani, B.M.2
Krotkova, A.3
Forbush, K.A.4
Laplace, C.5
Perlmutter, R.M.6
Von Boehmer, H.7
-
25
-
-
0032212728
-
LAT is required for TCR-mediated activation of PLCγ-1 and the Ras pathway
-
Finco, T.S., Kadlecek, T., Zhang, W., Samelson, L.E., and Weiss, A. (1998). LAT is required for TCR-mediated activation of PLCγ-1 and the Ras pathway. Immunity 9, 617-626.
-
(1998)
Immunity
, vol.9
, pp. 617-626
-
-
Finco, T.S.1
Kadlecek, T.2
Zhang, W.3
Samelson, L.E.4
Weiss, A.5
-
26
-
-
0032127159
-
BLNK: A central linker protein in B cell activation
-
Fu, C., Turck, C.W., Kurosaki, T., and Chan, A.C. (1998). BLNK: A central linker protein in B cell activation. Immunity 9, 93-103.
-
(1998)
Immunity
, vol.9
, pp. 93-103
-
-
Fu, C.1
Turck, C.W.2
Kurosaki, T.3
Chan, A.C.4
-
27
-
-
0023729241
-
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
-
Goodnow, C.C., Crosbie, J., Adelstein, S., Lavoie, T.B., Smith-Gill, S.J., Brink, R.A., Pritchard-Briscoe, H., Wotherspoon, J.S., Loblay, R.H., Raphael, K., et al. (1988). Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334, 676-682.
-
(1988)
Nature
, vol.334
, pp. 676-682
-
-
Goodnow, C.C.1
Crosbie, J.2
Adelstein, S.3
Lavoie, T.B.4
Smith-Gill, S.J.5
Brink, R.A.6
Pritchard-Briscoe, H.7
Wotherspoon, J.S.8
Loblay, R.H.9
Raphael, K.10
-
28
-
-
0030294283
-
Fyn can partially substitute for Lck in T lymphocyte development
-
Groves, T., Smiley, P., Cooke, M.P., Forbush, K., Perlmutter, R.M., and Guidos, C.J. (1996). Fyn can partially substitute for Lck in T lymphocyte development. Immunity 5, 417-428.
-
(1996)
Immunity
, vol.5
, pp. 417-428
-
-
Groves, T.1
Smiley, P.2
Cooke, M.P.3
Forbush, K.4
Perlmutter, R.M.5
Guidos, C.J.6
-
29
-
-
0025868702
-
Resolution and characterization of pro-B and prepro-B cell stages in normal mouse bone marrow
-
Hardy, R.R., Carmack, C.E., Shinton, S.A., Kemp, J.D., and HayaKawa, K. (1991). Resolution and characterization of pro-B and prepro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173, 1213-1225.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 1213-1225
-
-
Hardy, R.R.1
Carmack, C.E.2
Shinton, S.A.3
Kemp, J.D.4
Hayakawa, K.5
-
30
-
-
0032494156
-
lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function
-
lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function. J. Exp. Med. 188, 931-939.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 931-939
-
-
Henning, S.W.1
Cantrell, D.A.2
-
31
-
-
0028784215
-
Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
-
Hibbs, M.L., Tarlinton, D.M., Armes, J., Grail, D., Hodgson, G., Maglitto, R., Stacker, S.A., and Dunn, A.R. (1995). Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell 83, 301-311.
-
(1995)
Cell
, vol.83
, pp. 301-311
-
-
Hibbs, M.L.1
Tarlinton, D.M.2
Armes, J.3
Grail, D.4
Hodgson, G.5
Maglitto, R.6
Stacker, S.A.7
Dunn, A.R.8
-
32
-
-
0030664126
-
Control of B cell development by Ras-mediated activation of Raf.
-
Iritani, B.M., Forbush, K.A., Farrar, M.A., and Perlmutter, R.M. (1997). Control of B cell development by Ras-mediated activation of Raf. EMBO J. 16, 7019-7031.
-
(1997)
EMBO J.
, vol.16
, pp. 7019-7031
-
-
Iritani, B.M.1
Forbush, K.A.2
Farrar, M.A.3
Perlmutter, R.M.4
-
33
-
-
0028209548
-
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
-
Iwashima, M., Irving, B.A., van Oers, N.S., Chan, A.C., and Weiss, A. (1994). Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 263, 1136-1139.
-
(1994)
Science
, vol.263
, pp. 1136-1139
-
-
Iwashima, M.1
Irving, B.A.2
Van Oers, N.S.3
Chan, A.C.4
Weiss, A.5
-
34
-
-
0026486816
-
Pleiotropic effects of a null mutation in the c-fos proto-oncogene
-
Johnson, R.S., Spiegelman, B.M., and Papaioannou, V. (1992). Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell 71, 577-586.
-
(1992)
Cell
, vol.71
, pp. 577-586
-
-
Johnson, R.S.1
Spiegelman, B.M.2
Papaioannou, V.3
-
35
-
-
0027219303
-
A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture
-
Johnson, R.S., van Lingen, B., Papaioannou, V.E., and Spiegelman, B.M. (1993). A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev. 7, 1309-1317.
-
(1993)
Genes Dev.
, vol.7
, pp. 1309-1317
-
-
Johnson, R.S.1
Van Lingen, B.2
Papaioannou, V.E.3
Spiegelman, B.M.4
-
36
-
-
0029837933
-
Surrogate light chain in B cell development
-
Karasuyama, H., Rolink, A., and Melchers, F. (1996). Surrogate light chain in B cell development. Adv. Immunol. 63, 1-41.
-
(1996)
Adv. Immunol.
, vol.63
, pp. 1-41
-
-
Karasuyama, H.1
Rolink, A.2
Melchers, F.3
-
37
-
-
0029882331
-
Regulation of BCR- and PKC/Ca(2+)-mediated activation of the Raf1/MEK/MAPK pathway by protein-tyrosine kinase and -tyrosine phosphatase activities
-
Kawauchi, K., Lazarus, A.H., Sanghera, J.S., Man, G.L., Pelech, S.L., and Delovitch, T.L. (1996). Regulation of BCR- and PKC/Ca(2+)-mediated activation of the Raf1/MEK/MAPK pathway by protein-tyrosine kinase and -tyrosine phosphatase activities. Mol. Immunol. 33, 287-296.
-
(1996)
Mol. Immunol.
, vol.33
, pp. 287-296
-
-
Kawauchi, K.1
Lazarus, A.H.2
Sanghera, J.S.3
Man, G.L.4
Pelech, S.L.5
Delovitch, T.L.6
-
38
-
-
0032518916
-
Regulation of c-myc expression by Ras/Raf signaling
-
Kerkhoff, E., Houben, R., Loffler, S., Troppmair, J., Lee, J.E., and Rapp, U.R. (1998). Regulation of c-myc expression by Ras/Raf signaling. Oncogene 16, 211-216.
-
(1998)
Oncogene
, vol.16
, pp. 211-216
-
-
Kerkhoff, E.1
Houben, R.2
Loffler, S.3
Troppmair, J.4
Lee, J.E.5
Rapp, U.R.6
-
39
-
-
0025959244
-
Surface expression of the β T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells
-
Kishi, H., Borgulya, P., Scott, B., Karjalainen, K., Traunecker, A., Kaufman, J., and von Boehmer, H. (1991). Surface expression of the β T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells. EMBO J. 10, 93-100.
-
(1991)
EMBO J.
, vol.10
, pp. 93-100
-
-
Kishi, H.1
Borgulya, P.2
Scott, B.3
Karjalainen, K.4
Traunecker, A.5
Kaufman, J.6
Von Boehmer, H.7
-
41
-
-
0030498092
-
A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle
-
Li, Z., Dordai, D.I., Lee, J., and Desiderio, S. (1996). A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle. Immunity 5, 575-589.
-
(1996)
Immunity
, vol.5
, pp. 575-589
-
-
Li, Z.1
Dordai, D.I.2
Lee, J.3
Desiderio, S.4
-
42
-
-
0027296517
-
Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation
-
Lin, W.C., and Desiderio, S. (1993). Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation. Science 260, 953-959.
-
(1993)
Science
, vol.260
, pp. 953-959
-
-
Lin, W.C.1
Desiderio, S.2
-
43
-
-
0029886467
-
Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development
-
Loffert, D., Ehlich, A., Muller, W., and Rajewsky, K. (1996). Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development. Immunity 4, 133-144.
-
(1996)
Immunity
, vol.4
, pp. 133-144
-
-
Loffert, D.1
Ehlich, A.2
Muller, W.3
Rajewsky, K.4
-
44
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour, S.J., Matten, W.T., Hermann, A.S., Candia, J.M., Rong, S., Fukasawa, K., Vande Woude, G.F., and Ahn, N.G. (1994). Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265, 966-970.
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
Fukasawa, K.6
Vande Woude, G.F.7
Ahn, N.G.8
-
45
-
-
0030766009
-
B-lymphocyte-lineage cells from early precursors to Ig-secreting plasma cells: Targets of regulation by the myc/mad/max families of genes?
-
Melchers, F. (1997). B-lymphocyte-lineage cells from early precursors to Ig-secreting plasma cells: Targets of regulation by the myc/mad/max families of genes? Curr. Top. Microbiol. Immunol. 224, 19-30.
-
(1997)
Curr. Top. Microbiol. Immunol.
, vol.224
, pp. 19-30
-
-
Melchers, F.1
-
46
-
-
0026522204
-
lck
-
lck. Nature 357, 161-164.
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
Kishihara, K.2
Siderovski, D.P.3
Van Ewijk, W.4
Narendran, A.5
Timms, E.6
Wakeham, A.7
Paige, C.J.8
Hartmann, K.U.9
Veillette, A.10
-
47
-
-
0028467163
-
An activated lck transgene promotes thymocyte development in RAG-1 mutant mice
-
Mombaerts, P., Anderson, S.J., Perlmutter, R.M., Mak, T.W., and Tonegawa, S. (1994). An activated lck transgene promotes thymocyte development in RAG-1 mutant mice. Immunity 1, 261-267.
-
(1994)
Immunity
, vol.1
, pp. 261-267
-
-
Mombaerts, P.1
Anderson, S.J.2
Perlmutter, R.M.3
Mak, T.W.4
Tonegawa, S.5
-
48
-
-
0024446403
-
Intrathymic signaling in immature CD4+CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor ζ chain
-
Nakayama, T., Singer, A., Hsi, E.D., and Samelson, L.E. (1989). Intrathymic signaling in immature CD4+CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor ζ chain. Nature 341, 651-654.
-
(1989)
Nature
, vol.341
, pp. 651-654
-
-
Nakayama, T.1
Singer, A.2
Hsi, E.D.3
Samelson, L.E.4
-
49
-
-
0028806216
-
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
-
Nishizumi, H., Taniuchi, I., Yamanashi, Y., Kitamura, D., Ilic, D., Mori, S., Watanabe, T., and Yamamoto, T. (1995). Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. Immunity 3, 549-560.
-
(1995)
Immunity
, vol.3
, pp. 549-560
-
-
Nishizumi, H.1
Taniuchi, I.2
Yamanashi, Y.3
Kitamura, D.4
Ilic, D.5
Mori, S.6
Watanabe, T.7
Yamamoto, T.8
-
50
-
-
0029801381
-
Raf regulates positive selection
-
O'Shea, C.C., Crompton, T., Rosewell, I.R., Hayday, A.C., and Owen, M.J. (1996). Raf regulates positive selection. Eur. J. Immunol. 26, 2350-2355.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 2350-2355
-
-
O'Shea, C.C.1
Crompton, T.2
Rosewell, I.R.3
Hayday, A.C.4
Owen, M.J.5
-
51
-
-
0028821820
-
The cytoplasmic domains of immunoglobulin (Ig) α and Ig β can independently induce the precursor B cell transition and allelic exclusion
-
Papavasiliou, F., Jankovic, M., Suh, H., and Nussenzweig, M.C. (1995). The cytoplasmic domains of immunoglobulin (Ig) α and Ig β can independently induce the precursor B cell transition and allelic exclusion. J. Exp. Med. 182, 1389-1394.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1389-1394
-
-
Papavasiliou, F.1
Jankovic, M.2
Suh, H.3
Nussenzweig, M.C.4
-
53
-
-
0032563256
-
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
-
Pivniouk, V., Tsitsikov, E., Swinton, P., Rathbun, G., Alt, F.W., and Geha, R.S. (1998). Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell 94, 229-238.
-
(1998)
Cell
, vol.94
, pp. 229-238
-
-
Pivniouk, V.1
Tsitsikov, E.2
Swinton, P.3
Rathbun, G.4
Alt, F.W.5
Geha, R.S.6
-
54
-
-
0028027360
-
IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development
-
Rolink, A., Grawunder, U., Winkler, T.H., Karasuyama, H., and Melchers, F. (1994). IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development. Int. Immunol. 6, 1257-1264.
-
(1994)
Int. Immunol.
, vol.6
, pp. 1257-1264
-
-
Rolink, A.1
Grawunder, U.2
Winkler, T.H.3
Karasuyama, H.4
Melchers, F.5
-
55
-
-
0026032665
-
Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription
-
Schlissel, M.S., Corcoran, L.M., and Baltimore, D. (1991). Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription. J. Exp. Med. 173, 711-720.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 711-720
-
-
Schlissel, M.S.1
Corcoran, L.M.2
Baltimore, D.3
-
56
-
-
0027769386
-
Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated
-
Schlissel, M., Constantinescu, A., Morrow, T., Baxter, M., and Peng, A. (1993). Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 7, 2520-2532.
-
(1993)
Genes Dev.
, vol.7
, pp. 2520-2532
-
-
Schlissel, M.1
Constantinescu, A.2
Morrow, T.3
Baxter, M.4
Peng, A.5
-
57
-
-
0028136726
-
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
-
Scott, E.W., Simon, M.C., Anastasi, J., and Singh, H. (1994). Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265, 1573-1577.
-
(1994)
Science
, vol.265
, pp. 1573-1577
-
-
Scott, E.W.1
Simon, M.C.2
Anastasi, J.3
Singh, H.4
-
58
-
-
0030611964
-
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
-
Scott, E.W., Fisher, R.C., Olson, M.C., Kehrli, E.W., Simon, M.C., and Singh, H. (1997). PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity 6, 437-447.
-
(1997)
Immunity
, vol.6
, pp. 437-447
-
-
Scott, E.W.1
Fisher, R.C.2
Olson, M.C.3
Kehrli, E.W.4
Simon, M.C.5
Singh, H.6
-
59
-
-
0028143002
-
Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII
-
Seger, R., Seger, D., Reszka, A.A., Munar, E.S., Eldar-Finkelman, H., Dobrowolska, G., Jensen, A.M., Campbell, J.S., Fischer, E.H., and Krebs, E.G. (1994). Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII. J. Biol. Chem. 269, 25699-25709.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25699-25709
-
-
Seger, R.1
Seger, D.2
Reszka, A.A.3
Munar, E.S.4
Eldar-Finkelman, H.5
Dobrowolska, G.6
Jensen, A.M.7
Campbell, J.S.8
Fischer, E.H.9
Krebs, E.G.10
-
60
-
-
0031448222
-
The influence of the MAPK pathway on T cell lineage commitment
-
Sharp, L.L., Schwarz, D.A., Bott, C.M., Marshall, C.J., and Hedrick, S.M. (1997). The influence of the MAPK pathway on T cell lineage commitment. Immunity 7, 609-618.
-
(1997)
Immunity
, vol.7
, pp. 609-618
-
-
Sharp, L.L.1
Schwarz, D.A.2
Bott, C.M.3
Marshall, C.J.4
Hedrick, S.M.5
-
61
-
-
0033521687
-
Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient Pro-B lymphocytes
-
Shaw, A.C., Swat, W., Ferrini, R., Davidson, L., and Alt, F.W. (1999). Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient Pro-B lymphocytes. J. Exp. Med. 189, 123-129.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 123-129
-
-
Shaw, A.C.1
Swat, W.2
Ferrini, R.3
Davidson, L.4
Alt, F.W.5
-
62
-
-
0026581936
-
Rag-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
-
Shinkai, Y., Rathbun, G., Lam, K.P., Oltz, E.M., Stewart, V., Mendelsohn, M., Charron, J., Datta, M., Young, F., Stall, A.M., et al. (1992). Rag-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855-867.
-
(1992)
Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.P.3
Oltz, E.M.4
Stewart, V.5
Mendelsohn, M.6
Charron, J.7
Datta, M.8
Young, F.9
Stall, A.M.10
-
63
-
-
0027406812
-
Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes
-
Shinkai, Y., Koyasu, S., Nakayama, K., Murphy, K.M., Loh, D.Y., Reinherz, E.L., and Alt, F.W. (1993). Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes. Science 259, 822-825.
-
(1993)
Science
, vol.259
, pp. 822-825
-
-
Shinkai, Y.1
Koyasu, S.2
Nakayama, K.3
Murphy, K.M.4
Loh, D.Y.5
Reinherz, E.L.6
Alt, F.W.7
-
64
-
-
0028220059
-
Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice
-
Spanopoulou, E., Roman, C.A., Corcoran, L.M., Schlissel, M.S., Silver, D.P., Nemazee, D., Nussenzweig, M.C., Shinton, S.A., Hardy, R.R., and Baltimore, D. (1994). Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice. Genes Dev. 8, 1030-1042.
-
(1994)
Genes Dev.
, vol.8
, pp. 1030-1042
-
-
Spanopoulou, E.1
Roman, C.A.2
Corcoran, L.M.3
Schlissel, M.S.4
Silver, D.P.5
Nemazee, D.6
Nussenzweig, M.C.7
Shinton, S.A.8
Hardy, R.R.9
Baltimore, D.10
-
65
-
-
0026612411
-
fyn mutant mice display differential signaling in thymocytes and peripheral T cells
-
fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70, 741-750.
-
(1992)
Cell
, vol.70
, pp. 741-750
-
-
Stein, P.L.1
Lee, H.M.2
Rich, S.3
Soriano, P.4
-
66
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Erratum: Science 266(5192), 1994
-
Stokoe, D., Macdonald, S.G., Cadwallader, K., Symons, M., and Hancock, J.F. (1994). Activation of Raf as a result of recruitment to the plasma membrane. Science 264, 1463-1467. Erratum: Science 266(5192), 1994.
-
(1994)
Science
, vol.264
, pp. 1463-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
67
-
-
0028985017
-
ras distinguishes positive and negative selection in thymocytes
-
ras distinguishes positive and negative selection in thymocytes. Embo J. 14, 276-285.
-
(1995)
Embo J.
, vol.14
, pp. 276-285
-
-
Swan, K.A.1
Alberola-Ila, J.2
Gross, J.A.3
Appleby, M.W.4
Forbush, K.A.5
Thomas, J.F.6
Perlmutter, R.M.7
-
68
-
-
0030022930
-
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes
-
Swat, W., Shinkai, Y., Cheng, H.L., Davidson, L., and Alt, F.W. (1996). Activated Ras signals differentiation and expansion of CD4+8+ thymocytes. Proc. Natl. Acad. Sci. USA 93, 4683-4687.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4683-4687
-
-
Swat, W.1
Shinkai, Y.2
Cheng, H.L.3
Davidson, L.4
Alt, F.W.5
-
69
-
-
0030765923
-
Changes in the V(H) gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor
-
ten Boekel, E., Melchers, F., and Rolink, A.G. (1997). Changes in the V(H) gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor. Immunity 7, 357-368.
-
(1997)
Immunity
, vol.7
, pp. 357-368
-
-
Ten Boekel, E.1
Melchers, F.2
Rolink, A.G.3
-
70
-
-
0023908196
-
Somatic generation of immune diversity
-
Tonegawa, S. (1988). Somatic generation of immune diversity. Biosci. Rep. 8, 3-26.
-
(1988)
Biosci. Rep.
, vol.8
, pp. 3-26
-
-
Tonegawa, S.1
-
71
-
-
0028889302
-
Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
-
Turner, M., Mee, P.J., Costello, P.S., Williams, O., Price, A.A., Duddy, L.P., Furlong, M.T., Geahlen, R.L., and Tybulewicz, V.L. (1995). Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 378, 298-302.
-
(1995)
Nature
, vol.378
, pp. 298-302
-
-
Turner, M.1
Mee, P.J.2
Costello, P.S.3
Williams, O.4
Price, A.A.5
Duddy, L.P.6
Furlong, M.T.7
Geahlen, R.L.8
Tybulewicz, V.L.9
-
72
-
-
0030009253
-
The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination
-
van Gent, D.C., Ramsden, D.A., and Gellert, M. (1996). The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination. Cell 85, 107-113.
-
(1996)
Cell
, vol.85
, pp. 107-113
-
-
Van Gent, D.C.1
Ramsden, D.A.2
Gellert, M.3
-
73
-
-
0027228369
-
Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) ζ subunit: Regulation of TCR-associated protein tyrosine kinase activity by TCR ζ
-
van Oers, N.S., Tao, W., Watts, J.D., Johnson, P., Aebersold, R., and Teh, H.S. (1993). Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) ζ subunit: Regulation of TCR-associated protein tyrosine kinase activity by TCR ζ. Mol. Cell. Biol. 13, 5771-5780.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 5771-5780
-
-
Van Oers, N.S.1
Tao, W.2
Watts, J.D.3
Johnson, P.4
Aebersold, R.5
Teh, H.S.6
-
74
-
-
0028877062
-
The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit
-
van Oers, N.S., von Boehmer, H., and Weiss, A. (1995). The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit. J. Exp. Med. 182, 1585-1590.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1585-1590
-
-
Van Oers, N.S.1
Von Boehmer, H.A.2
Weiss, A.3
-
75
-
-
0030293791
-
αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases
-
van Oers, N.S., Lowin-Kropf, B., Finlay, D., Connolly, K., and Weiss, A. (1996). αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity 5, 429-436.
-
(1996)
Immunity
, vol.5
, pp. 429-436
-
-
Van Oers, N.S.1
Lowin-Kropf, B.2
Finlay, D.3
Connolly, K.4
Weiss, A.5
-
76
-
-
0030963615
-
Structure and function of the pre-T cell receptor
-
von Boehmer, H., and Fehling, H.J. (1997). Structure and function of the pre-T cell receptor. Annu. Rev. Immunol. 15, 433-452.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 433-452
-
-
Von Boehmer, H.A.1
Fehling, H.J.2
-
77
-
-
0022385230
-
A transgenic immunoglobulin μ gene prevents rearrangement of endogenous genes
-
Weaver, D., Costantini, F., Imanishi-Kari, T., and Baltimore, D.(1985). A transgenic immunoglobulin μ gene prevents rearrangement of endogenous genes. Cell 42, 117-127.
-
(1985)
Cell
, vol.42
, pp. 117-127
-
-
Weaver, D.1
Costantini, F.2
Imanishi-Kari, T.3
Baltimore, D.4
-
78
-
-
0032541062
-
Uncoupling of nonreceptor tyrosine kinases from PLC-γ1 in an SLP-76-deficient T cell
-
Yablonski, D., Kuhne, M.R., Kadlecek, T., and Weiss, A. (1998). Uncoupling of nonreceptor tyrosine kinases from PLC-γ1 in an SLP-76-deficient T cell. Science 281, 413-416.
-
(1998)
Science
, vol.281
, pp. 413-416
-
-
Yablonski, D.1
Kuhne, M.R.2
Kadlecek, T.3
Weiss, A.4
-
79
-
-
0032079317
-
Defective trophoblast function in mice with a targeted mutation of Ets2
-
Yamamoto, H., Flannery, M.L., Kupriyanov, S., Pearce, J., McKercher, S.R., Henkel, G.W., Maki, R.A., Werb, Z., and Oshima, R.G. (1998). Defective trophoblast function in mice with a targeted mutation of Ets2. Genes Dev. 12, 1315-1326.
-
(1998)
Genes Dev.
, vol.12
, pp. 1315-1326
-
-
Yamamoto, H.1
Flannery, M.L.2
Kupriyanov, S.3
Pearce, J.4
McKercher, S.R.5
Henkel, G.W.6
Maki, R.A.7
Werb, Z.8
Oshima, R.G.9
-
80
-
-
0028347698
-
Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation
-
Young, F., Ardman, B., Shinkai, Y., Lansford, R., Blackwell, T.K., Mendelsohn, M., Rolink, A., Melchers, F., and Alt, F.W. (1994). Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation. Genes Dev. 8,1043-1057.
-
(1994)
Genes Dev.
, vol.8
, pp. 1043-1057
-
-
Young, F.1
Ardman, B.2
Shinkai, Y.3
Lansford, R.4
Blackwell, T.K.5
Mendelsohn, M.6
Rolink, A.7
Melchers, F.8
Alt, F.W.9
-
81
-
-
0013564338
-
-
Erratum
-
Genes Dev. 9(24), 1995.
-
(1995)
Genes Dev.
, vol.9
, Issue.24
-
-
-
82
-
-
0033103833
-
Essential role of LAT in T cell development
-
Zhang, W., Sommers, C.L., Burshtyn, D.N., Stebbins, C.C., DeJarnette, J.B., Trible, R.P., Grinberg, A., Tsay, H.C., Jacobs, H.M., Kessler, C.M., et al. (1999). Essential role of LAT in T cell development. Immunity 10, 323-332.
-
(1999)
Immunity
, vol.10
, pp. 323-332
-
-
Zhang, W.1
Sommers, C.L.2
Burshtyn, D.N.3
Stebbins, C.C.4
DeJarnette, J.B.5
Trible, R.P.6
Grinberg, A.7
Tsay, H.C.8
Jacobs, H.M.9
Kessler, C.M.10
-
83
-
-
0030999886
-
Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases
-
Zou, X., Rudchenko, S., Wong, K., and Calame, K. (1997). Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases. Genes Dev. 11, 654-662.
-
(1997)
Genes Dev.
, vol.11
, pp. 654-662
-
-
Zou, X.1
Rudchenko, S.2
Wong, K.3
Calame, K.4
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