메뉴 건너뛰기




Volumn 110, Issue , 2017, Pages 117-132

Paradoxical roles of dual oxidases in cancer biology

Author keywords

DUOX; EGFR; Epigenetics; Epithelial; NADPH oxidase; NOX; Reactive oxygen species

Indexed keywords

DUAL OXIDASE; DUAL OXIDASE 1; DUAL OXIDASE 2; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 5; UNCLASSIFIED DRUG; DUOX1 PROTEIN, HUMAN; DUOX2 PROTEIN, HUMAN;

EID: 85020475760     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2017.05.024     Document Type: Review
Times cited : (39)

References (272)
  • 1
    • 1542406446 scopus 로고    scopus 로고
    • NOX enzymes and the biology of reactive oxygen
    • [1] Lambeth, J.D., NOX enzymes and the biology of reactive oxygen. Nat. Rev. Immunol. 4:3 (2004), 181–189.
    • (2004) Nat. Rev. Immunol. , vol.4 , Issue.3 , pp. 181-189
    • Lambeth, J.D.1
  • 2
    • 84897019491 scopus 로고    scopus 로고
    • Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited
    • [2] Lambeth, J.D., Neish, A.S., Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited. Annu. Rev. Pathol. 9 (2014), 119–145.
    • (2014) Annu. Rev. Pathol. , vol.9 , pp. 119-145
    • Lambeth, J.D.1    Neish, A.S.2
  • 3
    • 84901316606 scopus 로고    scopus 로고
    • Cellular mechanisms and physiological consequences of redox-dependent signalling
    • [3] Holmstrom, K.M., Finkel, T., Cellular mechanisms and physiological consequences of redox-dependent signalling. Nat. Rev. Mol. Cell Biol. 15:6 (2014), 411–421.
    • (2014) Nat. Rev. Mol. Cell Biol. , vol.15 , Issue.6 , pp. 411-421
    • Holmstrom, K.M.1    Finkel, T.2
  • 6
    • 84998893299 scopus 로고    scopus 로고
    • Redox control of senescence and age-related disease
    • [6] Chandrasekaran, A., Idelchik, M.D., Melendez, J.A., Redox control of senescence and age-related disease. Redox Biol. 11 (2016), 91–102.
    • (2016) Redox Biol. , vol.11 , pp. 91-102
    • Chandrasekaran, A.1    Idelchik, M.D.2    Melendez, J.A.3
  • 7
    • 85010683524 scopus 로고    scopus 로고
    • Diabetes-induced reactive oxygen species: mechanism of their generation and role in renal injury
    • [7] Fakhruddin, S., Alanazi, W., Jackson, K.E., Diabetes-induced reactive oxygen species: mechanism of their generation and role in renal injury. J. Diabetes Res., 2017, 2017, 8379327.
    • (2017) J. Diabetes Res. , vol.2017 , pp. 8379327
    • Fakhruddin, S.1    Alanazi, W.2    Jackson, K.E.3
  • 8
    • 85013350343 scopus 로고    scopus 로고
    • Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis
    • [8] Forstermann, U., Xia, N., Li, H., Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis. Circ. Res. 120:4 (2017), 713–735.
    • (2017) Circ. Res. , vol.120 , Issue.4 , pp. 713-735
    • Forstermann, U.1    Xia, N.2    Li, H.3
  • 10
    • 84905858696 scopus 로고    scopus 로고
    • ROS signalling, NADPH oxidases and cancer
    • [10] Landry, W.D., Cotter, T.G., ROS signalling, NADPH oxidases and cancer. Biochem. Soc. Trans. 42:4 (2014), 934–938.
    • (2014) Biochem. Soc. Trans. , vol.42 , Issue.4 , pp. 934-938
    • Landry, W.D.1    Cotter, T.G.2
  • 11
    • 84962788149 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) and cancer: role of antioxidative nutraceuticals
    • [11] Prasad, S., Gupta, S.C., Tyagi, A.K., Reactive oxygen species (ROS) and cancer: role of antioxidative nutraceuticals. Cancer Lett. 387 (2017), 95–105.
    • (2017) Cancer Lett. , vol.387 , pp. 95-105
    • Prasad, S.1    Gupta, S.C.2    Tyagi, A.K.3
  • 12
    • 84990224053 scopus 로고    scopus 로고
    • Fundamentals of cancer metabolism
    • [12] DeBerardinis, R.J., Chandel, N.S., Fundamentals of cancer metabolism. Sci. Adv., 2(5), 2016, e1600200.
    • (2016) Sci. Adv. , vol.2 , Issue.5 , pp. e1600200
    • DeBerardinis, R.J.1    Chandel, N.S.2
  • 13
    • 84866425239 scopus 로고    scopus 로고
    • Aiding and abetting roles of NOX oxidases in cellular transformation
    • [13] Block, K., Gorin, Y., Aiding and abetting roles of NOX oxidases in cellular transformation. Nat. Rev. Cancer 12:9 (2012), 627–637.
    • (2012) Nat. Rev. Cancer , vol.12 , Issue.9 , pp. 627-637
    • Block, K.1    Gorin, Y.2
  • 15
    • 77953456358 scopus 로고    scopus 로고
    • Vitamin e and N-acetylcysteine as antioxidant adjuvant therapy in children with acute lymphoblastic leukemia
    • [15] Al-Tonbary, Y., Al-Haggar, M., El-Ashry, R., El-Dakroory, S., Azzam, H., Fouda, A., Vitamin e and N-acetylcysteine as antioxidant adjuvant therapy in children with acute lymphoblastic leukemia. Adv. Hematol., 2009, 2009, 689639.
    • (2009) Adv. Hematol. , vol.2009 , pp. 689639
    • Al-Tonbary, Y.1    Al-Haggar, M.2    El-Ashry, R.3    El-Dakroory, S.4    Azzam, H.5    Fouda, A.6
  • 17
    • 84894477345 scopus 로고    scopus 로고
    • Cisplatin otoprotection using transtympanic L-N-acetylcysteine: a pilot randomized study in head and neck cancer patients
    • [17] Yoo, J., Hamilton, S.J., Angel, D., Fung, K., Franklin, J., Parnes, L.S., Lewis, D., Venkatesan, V., Winquist, E., Cisplatin otoprotection using transtympanic L-N-acetylcysteine: a pilot randomized study in head and neck cancer patients. Laryngoscope 124:3 (2014), E87–E94.
    • (2014) Laryngoscope , vol.124 , Issue.3 , pp. E87-E94
    • Yoo, J.1    Hamilton, S.J.2    Angel, D.3    Fung, K.4    Franklin, J.5    Parnes, L.S.6    Lewis, D.7    Venkatesan, V.8    Winquist, E.9
  • 18
    • 0031158107 scopus 로고    scopus 로고
    • Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: results of a double-blind, randomised trial
    • [18] Smyth, J.F., Bowman, A., Perren, T., Wilkinson, P., Prescott, R.J., Quinn, K.J., Tedeschi, M., Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: results of a double-blind, randomised trial. Ann. Oncol.: Off. J. Eur. Soc. Med. Oncol. 8:6 (1997), 569–573.
    • (1997) Ann. Oncol.: Off. J. Eur. Soc. Med. Oncol. , vol.8 , Issue.6 , pp. 569-573
    • Smyth, J.F.1    Bowman, A.2    Perren, T.3    Wilkinson, P.4    Prescott, R.J.5    Quinn, K.J.6    Tedeschi, M.7
  • 19
    • 0034725945 scopus 로고    scopus 로고
    • Glutathione in the prevention of cisplatin induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer
    • [19] Schmidinger, M., Budinsky, A.C., Wenzel, C., Piribauer, M., Brix, R., Kautzky, M., Oder, W., Locker, G.J., Zielinski, C.C., Steger, G.G., Glutathione in the prevention of cisplatin induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer. Wien. Klin. Wochenschr. 112:14 (2000), 617–623.
    • (2000) Wien. Klin. Wochenschr. , vol.112 , Issue.14 , pp. 617-623
    • Schmidinger, M.1    Budinsky, A.C.2    Wenzel, C.3    Piribauer, M.4    Brix, R.5    Kautzky, M.6    Oder, W.7    Locker, G.J.8    Zielinski, C.C.9    Steger, G.G.10
  • 22
    • 0028815902 scopus 로고
    • Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo-controlled trial
    • [22] Cascinu, S., Cordella, L., Del Ferro, E., Fronzoni, M., Catalano, G., Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: a randomized double-blind placebo-controlled trial. J. Clin. Oncol.: Off. J. Am. Soc. Clin. Oncol. 13:1 (1995), 26–32.
    • (1995) J. Clin. Oncol.: Off. J. Am. Soc. Clin. Oncol. , vol.13 , Issue.1 , pp. 26-32
    • Cascinu, S.1    Cordella, L.2    Del Ferro, E.3    Fronzoni, M.4    Catalano, G.5
  • 26
    • 70449107252 scopus 로고    scopus 로고
    • Redox-directed cancer therapeutics: molecular mechanisms and opportunities
    • [26] Wondrak, G.T., Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid. Redox Signal. 11:12 (2009), 3013–3069.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.12 , pp. 3013-3069
    • Wondrak, G.T.1
  • 30
    • 0035659227 scopus 로고    scopus 로고
    • Effect of mitochondrial electron transport chain inhibitors on superoxide radical generation in rat hippocampal and striatal slices
    • [30] Saybasili, H., Yuksel, M., Haklar, G., Yalcin, A.S., Effect of mitochondrial electron transport chain inhibitors on superoxide radical generation in rat hippocampal and striatal slices. Antioxid. Redox Signal. 3:6 (2001), 1099–1104.
    • (2001) Antioxid. Redox Signal. , vol.3 , Issue.6 , pp. 1099-1104
    • Saybasili, H.1    Yuksel, M.2    Haklar, G.3    Yalcin, A.S.4
  • 31
    • 84920465752 scopus 로고    scopus 로고
    • Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer
    • [31] Li, L., Fath, M.A., Scarbrough, P.M., Watson, W.H., Spitz, D.R., Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer. Redox Biol. 4 (2015), 127–135.
    • (2015) Redox Biol. , vol.4 , pp. 127-135
    • Li, L.1    Fath, M.A.2    Scarbrough, P.M.3    Watson, W.H.4    Spitz, D.R.5
  • 32
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • [32] Vander Heiden, M.G., Cantley, L.C., Thompson, C.B., Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324:5930 (2009), 1029–1033.
    • (2009) Science , vol.324 , Issue.5930 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 33
    • 84990224053 scopus 로고    scopus 로고
    • Fundamentals of cancer metabolism
    • [33] DeBerardinis, R.J., Chandel, N.S., Fundamentals of cancer metabolism. Sci. Adv., 2(5), 2016, e1600200.
    • (2016) Sci. Adv. , vol.2 , Issue.5 , pp. e1600200
    • DeBerardinis, R.J.1    Chandel, N.S.2
  • 34
    • 85015733199 scopus 로고    scopus 로고
    • Cancer metabolism: fueling more than just growth
    • [34] Lee, N., Kim, D., Cancer metabolism: fueling more than just growth. Mol. Cells 39:12 (2016), 847–854.
    • (2016) Mol. Cells , vol.39 , Issue.12 , pp. 847-854
    • Lee, N.1    Kim, D.2
  • 38
    • 84966589393 scopus 로고    scopus 로고
    • Mitochondrial ROS regulation of proliferating cells
    • [38] Diebold, L., Chandel, N.S., Mitochondrial ROS regulation of proliferating cells. Free Radic. Biol. Med. 100 (2016), 86–93.
    • (2016) Free Radic. Biol. Med. , vol.100 , pp. 86-93
    • Diebold, L.1    Chandel, N.S.2
  • 39
    • 84866565340 scopus 로고    scopus 로고
    • Modulating mitochondrial intracellular location as a redox signal
    • [39] Murphy, M.P., Modulating mitochondrial intracellular location as a redox signal. Sci. Signal., 5(242), 2012, pe39.
    • (2012) Sci. Signal. , vol.5 , Issue.242 , pp. pe39
    • Murphy, M.P.1
  • 40
    • 84864344675 scopus 로고    scopus 로고
    • Targeting NADPH oxidases for the treatment of cancer and inflammation
    • [40] Bonner, M.Y., Arbiser, J.L., Targeting NADPH oxidases for the treatment of cancer and inflammation. Cell. Mol. Life Sci.: CMLS 69:14 (2012), 2435–2442.
    • (2012) Cell. Mol. Life Sci.: CMLS , vol.69 , Issue.14 , pp. 2435-2442
    • Bonner, M.Y.1    Arbiser, J.L.2
  • 42
    • 73949101383 scopus 로고    scopus 로고
    • Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation
    • [42] Diaz, B., Shani, G., Pass, I., Anderson, D., Quintavalle, M., Courtneidge, S.A., Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation. Sci. Signal., 2(88), 2009, ra53.
    • (2009) Sci. Signal. , vol.2 , Issue.88 , pp. ra53
    • Diaz, B.1    Shani, G.2    Pass, I.3    Anderson, D.4    Quintavalle, M.5    Courtneidge, S.A.6
  • 43
    • 34547116452 scopus 로고    scopus 로고
    • Nox1 redox signaling mediates oncogenic Ras-induced disruption of stress fibers and focal adhesions by down-regulating Rho
    • [43] Shinohara, M., Shang, W.H., Kubodera, M., Harada, S., Mitsushita, J., Kato, M., Miyazaki, H., Sumimoto, H., Kamata, T., Nox1 redox signaling mediates oncogenic Ras-induced disruption of stress fibers and focal adhesions by down-regulating Rho. J. Biol. Chem. 282:24 (2007), 17640–17648.
    • (2007) J. Biol. Chem. , vol.282 , Issue.24 , pp. 17640-17648
    • Shinohara, M.1    Shang, W.H.2    Kubodera, M.3    Harada, S.4    Mitsushita, J.5    Kato, M.6    Miyazaki, H.7    Sumimoto, H.8    Kamata, T.9
  • 44
    • 80052266526 scopus 로고    scopus 로고
    • Cross talk between mitochondria and NADPH oxidases
    • [44] Dikalov, S., Cross talk between mitochondria and NADPH oxidases. Free Radic. Biol. Med. 51:7 (2011), 1289–1301.
    • (2011) Free Radic. Biol. Med. , vol.51 , Issue.7 , pp. 1289-1301
    • Dikalov, S.1
  • 47
    • 84875103455 scopus 로고    scopus 로고
    • Balancing reactive oxygen species in the epigenome: nadph oxidases as target and perpetrator
    • [47] Hayes, P., Knaus, U.G., Balancing reactive oxygen species in the epigenome: nadph oxidases as target and perpetrator. Antioxid. Redox Signal. 18:15 (2013), 1937–1945.
    • (2013) Antioxid. Redox Signal. , vol.18 , Issue.15 , pp. 1937-1945
    • Hayes, P.1    Knaus, U.G.2
  • 49
    • 0042203535 scopus 로고    scopus 로고
    • Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense
    • [49] Geiszt, M., Witta, J., Baffi, J., Lekstrom, K., Leto, T.L., Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense. FASEB J.: Off. Publ. Fed. Am. Soc. Exp. Biol. 17:11 (2003), 1502–1504.
    • (2003) FASEB J.: Off. Publ. Fed. Am. Soc. Exp. Biol. , vol.17 , Issue.11 , pp. 1502-1504
    • Geiszt, M.1    Witta, J.2    Baffi, J.3    Lekstrom, K.4    Leto, T.L.5
  • 52
    • 39449091629 scopus 로고    scopus 로고
    • Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer
    • [52](a) Luxen, S., Belinsky, S.A., Knaus, U.G., Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer. Cancer Res. 68:4 (2008), 1037–1045.
    • (2008) Cancer Res. , vol.68 , Issue.4 , pp. 1037-1045
    • Luxen, S.1    Belinsky, S.A.2    Knaus, U.G.3
  • 53
    • 0038365368 scopus 로고    scopus 로고
    • Analysis of Microarray Data Using Z Score Transformation
    • [52](b) Cheadle, C., Vawter, M.P., Freed, W.J., Becker, K.G., Analysis of Microarray Data Using Z Score Transformation. J. Mol. Diagn. 5:2 (2003), 73–81.
    • (2003) J. Mol. Diagn. , vol.5 , Issue.2 , pp. 73-81
    • Cheadle, C.1    Vawter, M.P.2    Freed, W.J.3    Becker, K.G.4
  • 54
    • 84964305168 scopus 로고    scopus 로고
    • The combination of three molecular markers can be a valuable predictive tool for the prognosis of hepatocellular carcinoma patients
    • [53] Chen, S.S., Yu, K.K., Ling, Q.X., Huang, C., Li, N., Zheng, J.M., Bao, S.X., Cheng, Q., Zhu, M.Q., Chen, M.Q., The combination of three molecular markers can be a valuable predictive tool for the prognosis of hepatocellular carcinoma patients. Sci. Rep., 6, 2016, 24582.
    • (2016) Sci. Rep. , vol.6 , pp. 24582
    • Chen, S.S.1    Yu, K.K.2    Ling, Q.X.3    Huang, C.4    Li, N.5    Zheng, J.M.6    Bao, S.X.7    Cheng, Q.8    Zhu, M.Q.9    Chen, M.Q.10
  • 56
    • 0036710445 scopus 로고    scopus 로고
    • The superoxide-generating NADPH oxidase: structural aspects and activation mechanism
    • [55] Vignais, P.V., The superoxide-generating NADPH oxidase: structural aspects and activation mechanism. Cell. Mol. Life Sci. CMLS 59:9 (2002), 1428–1459.
    • (2002) Cell. Mol. Life Sci. CMLS , vol.59 , Issue.9 , pp. 1428-1459
    • Vignais, P.V.1
  • 57
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
    • [56] Bedard, K., Krause, K.H., The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 87:1 (2007), 245–313.
    • (2007) Physiol. Rev. , vol.87 , Issue.1 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 58
    • 84907455071 scopus 로고    scopus 로고
    • Nox family NADPH oxidases: molecular mechanisms of activation
    • [57] Brandes, R.P., Weissmann, N., Schroder, K., Nox family NADPH oxidases: molecular mechanisms of activation. Free Radic. Biol. Med. 76 (2014), 208–226.
    • (2014) Free Radic. Biol. Med. , vol.76 , pp. 208-226
    • Brandes, R.P.1    Weissmann, N.2    Schroder, K.3
  • 59
    • 33750926794 scopus 로고    scopus 로고
    • Role of Nox family NADPH oxidases in host defense
    • [58] Leto, T.L., Geiszt, M., Role of Nox family NADPH oxidases in host defense. Antioxid. Redox Signal. 8:9–10 (2006), 1549–1561.
    • (2006) Antioxid. Redox Signal. , vol.8 , Issue.9-10 , pp. 1549-1561
    • Leto, T.L.1    Geiszt, M.2
  • 61
    • 68749117502 scopus 로고    scopus 로고
    • Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway
    • [60] Naughton, R., Quiney, C., Turner, S.D., Cotter, T.G., Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway. Leukemia 23:8 (2009), 1432–1440.
    • (2009) Leukemia , vol.23 , Issue.8 , pp. 1432-1440
    • Naughton, R.1    Quiney, C.2    Turner, S.D.3    Cotter, T.G.4
  • 62
    • 79751534683 scopus 로고    scopus 로고
    • NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
    • [61] Reddy, M.M., Fernandes, M.S., Salgia, R., Levine, R.L., Griffin, J.D., Sattler, M., NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases. Leukemia 25:2 (2011), 281–289.
    • (2011) Leukemia , vol.25 , Issue.2 , pp. 281-289
    • Reddy, M.M.1    Fernandes, M.S.2    Salgia, R.3    Levine, R.L.4    Griffin, J.D.5    Sattler, M.6
  • 63
    • 1342281664 scopus 로고    scopus 로고
    • p22phox-Derived superoxide mediates enhanced proliferative capacity of diabetic vascular smooth muscle cells
    • [62] Jeong, H.Y., Jeong, H.Y., Kim, C.D., p22phox-Derived superoxide mediates enhanced proliferative capacity of diabetic vascular smooth muscle cells. Diabetes Res. Clin. Pract. 64:1 (2004), 1–10.
    • (2004) Diabetes Res. Clin. Pract. , vol.64 , Issue.1 , pp. 1-10
    • Jeong, H.Y.1    Jeong, H.Y.2    Kim, C.D.3
  • 66
    • 43949109594 scopus 로고    scopus 로고
    • Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras
    • [65] Laurent, E., McCoy, J.W. 3rd, Macina, R.A., Liu, W., Cheng, G., Robine, S., Papkoff, J., Lambeth, J.D., Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras. Int. J. Cancer 123:1 (2008), 100–107.
    • (2008) Int. J. Cancer , vol.123 , Issue.1 , pp. 100-107
    • Laurent, E.1    McCoy, J.W.2    Macina, R.A.3    Liu, W.4    Cheng, G.5    Robine, S.6    Papkoff, J.7    Lambeth, J.D.8
  • 67
    • 84934277211 scopus 로고    scopus 로고
    • NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7
    • [66] Banskota, S., Regmi, S.C., Kim, J.A., NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7. Mol. Cancer, 14, 2015, 123.
    • (2015) Mol. Cancer , vol.14 , pp. 123
    • Banskota, S.1    Regmi, S.C.2    Kim, J.A.3
  • 69
    • 85020432807 scopus 로고    scopus 로고
    • ROS mediates interferon gamma induced phosphorylation of Src, through the Raf/ERK pathway, in MCF-7 human breast cancer cell line
    • [68] Zibara, K., Zeidan, A., Bjeije, H., Kassem, N., Badran, B., El-Zein, N., ROS mediates interferon gamma induced phosphorylation of Src, through the Raf/ERK pathway, in MCF-7 human breast cancer cell line. J. Cell Commun. Signal., 2016.
    • (2016) J. Cell Commun. Signal.
    • Zibara, K.1    Zeidan, A.2    Bjeije, H.3    Kassem, N.4    Badran, B.5    El-Zein, N.6
  • 71
    • 85019992753 scopus 로고    scopus 로고
    • Association between NADPH oxidase (NOX) and lung cancer: a systematic review and meta-analysis
    • [70] Han, M., Zhang, T., Yang, L., Wang, Z., Ruan, J., Chang, X., Association between NADPH oxidase (NOX) and lung cancer: a systematic review and meta-analysis. J. Thorac. Dis. 8:7 (2016), 1704–1711.
    • (2016) J. Thorac. Dis. , vol.8 , Issue.7 , pp. 1704-1711
    • Han, M.1    Zhang, T.2    Yang, L.3    Wang, Z.4    Ruan, J.5    Chang, X.6
  • 72
    • 36348938884 scopus 로고    scopus 로고
    • Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor
    • [71] Xia, C., Meng, Q., Liu, L.Z., Rojanasakul, Y., Wang, X.R., Jiang, B.H., Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor. Cancer Res. 67:22 (2007), 10823–10830.
    • (2007) Cancer Res. , vol.67 , Issue.22 , pp. 10823-10830
    • Xia, C.1    Meng, Q.2    Liu, L.Z.3    Rojanasakul, Y.4    Wang, X.R.5    Jiang, B.H.6
  • 73
    • 84900564839 scopus 로고    scopus 로고
    • Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-beta-mediated migration of human lung and breast epithelial cells
    • [72] Boudreau, H.E., Casterline, B.W., Burke, D.J., Leto, T.L., Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-beta-mediated migration of human lung and breast epithelial cells. Br. J. Cancer 110:10 (2014), 2569–2582.
    • (2014) Br. J. Cancer , vol.110 , Issue.10 , pp. 2569-2582
    • Boudreau, H.E.1    Casterline, B.W.2    Burke, D.J.3    Leto, T.L.4
  • 75
    • 85019211516 scopus 로고    scopus 로고
    • Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancer
    • [74] Lin, X.L., Yang, L., Fu, S.W., Lin, W.F., Gao, Y.J., Chen, H.Y., Ge, Z.Z., Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancer. Oncotarget, 2017.
    • (2017) Oncotarget
    • Lin, X.L.1    Yang, L.2    Fu, S.W.3    Lin, W.F.4    Gao, Y.J.5    Chen, H.Y.6    Ge, Z.Z.7
  • 79
    • 33745978446 scopus 로고    scopus 로고
    • cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells
    • [78] Fu, X., Beer, D.G., Behar, J., Wands, J., Lambeth, D., Cao, W., cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells. J. Biol. Chem. 281:29 (2006), 20368–20382.
    • (2006) J. Biol. Chem. , vol.281 , Issue.29 , pp. 20368-20382
    • Fu, X.1    Beer, D.G.2    Behar, J.3    Wands, J.4    Lambeth, D.5    Cao, W.6
  • 82
    • 84948843956 scopus 로고    scopus 로고
    • NOX5-L can stimulate proliferation and apoptosis depending on its levels and cellular context, determining cancer cell susceptibility to cisplatin
    • [81] Dho, S.H., Kim, J.Y., Kwon, E.-S., Lim, J.C., Park, S.S., Kwon, K.-S., NOX5-L can stimulate proliferation and apoptosis depending on its levels and cellular context, determining cancer cell susceptibility to cisplatin. Oncotarget 6:36 (2015), 39235–39246.
    • (2015) Oncotarget , vol.6 , Issue.36 , pp. 39235-39246
    • Dho, S.H.1    Kim, J.Y.2    Kwon, E.-S.3    Lim, J.C.4    Park, S.S.5    Kwon, K.-S.6
  • 83
    • 84936882074 scopus 로고    scopus 로고
    • Redox-modulating agents target NOX2-dependent IKKepsilon oncogenic kinase expression and proliferation in human breast cancer cell lines
    • [82] Mukawera, E., Chartier, S., Williams, V., Pagano, P.J., Lapointe, R., Grandvaux, N., Redox-modulating agents target NOX2-dependent IKKepsilon oncogenic kinase expression and proliferation in human breast cancer cell lines. Redox Biol. 6 (2015), 9–18.
    • (2015) Redox Biol. , vol.6 , pp. 9-18
    • Mukawera, E.1    Chartier, S.2    Williams, V.3    Pagano, P.J.4    Lapointe, R.5    Grandvaux, N.6
  • 85
    • 85007536657 scopus 로고    scopus 로고
    • NOX2-ROS-HIF-1alpha signaling is critical for the inhibitory effect of oleanolic acid on rectal cancer cell proliferation
    • [84] Guo, Y., Han, B., Luo, K., Ren, Z., Cai, L., Sun, L., NOX2-ROS-HIF-1alpha signaling is critical for the inhibitory effect of oleanolic acid on rectal cancer cell proliferation. Biomed. Pharmacother. 85 (2017), 733–739.
    • (2017) Biomed. Pharmacother. , vol.85 , pp. 733-739
    • Guo, Y.1    Han, B.2    Luo, K.3    Ren, Z.4    Cai, L.5    Sun, L.6
  • 87
    • 84930861610 scopus 로고    scopus 로고
    • Relationship between expression of NADPH oxidase 2 and invasion and prognosis of human gastric cancer
    • [86] Wang, P., Shi, Q., Deng, W.H., Yu, J., Zuo, T., Mei, F.C., Wang, W.X., Relationship between expression of NADPH oxidase 2 and invasion and prognosis of human gastric cancer. World J. Gastroenterol. 21:20 (2015), 6271–6279.
    • (2015) World J. Gastroenterol. , vol.21 , Issue.20 , pp. 6271-6279
    • Wang, P.1    Shi, Q.2    Deng, W.H.3    Yu, J.4    Zuo, T.5    Mei, F.C.6    Wang, W.X.7
  • 88
    • 77954935934 scopus 로고    scopus 로고
    • Transtympanic administration of short interfering (si)RNA for the NOX3 isoform of NADPH oxidase protects against cisplatin-induced hearing loss in the rat
    • [87] Mukherjea, D., Jajoo, S., Kaur, T., Sheehan, K.E., Ramkumar, V., Rybak, L.P., Transtympanic administration of short interfering (si)RNA for the NOX3 isoform of NADPH oxidase protects against cisplatin-induced hearing loss in the rat. Antioxid. Redox Signal. 13:5 (2010), 589–598.
    • (2010) Antioxid. Redox Signal. , vol.13 , Issue.5 , pp. 589-598
    • Mukherjea, D.1    Jajoo, S.2    Kaur, T.3    Sheehan, K.E.4    Ramkumar, V.5    Rybak, L.P.6
  • 89
    • 65349125859 scopus 로고    scopus 로고
    • Identification of structural elements in Nox1 and Nox4 controlling localization and activity
    • [88] Helmcke, I., Heumuller, S., Tikkanen, R., Schroder, K., Brandes, R.P., Identification of structural elements in Nox1 and Nox4 controlling localization and activity. Antioxid. Redox Signal. 11:6 (2009), 1279–1287.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.6 , pp. 1279-1287
    • Helmcke, I.1    Heumuller, S.2    Tikkanen, R.3    Schroder, K.4    Brandes, R.P.5
  • 91
    • 84855471844 scopus 로고    scopus 로고
    • Redox signaling at invasive microdomains in cancer cells
    • [90] Díaz, B., Courtneidge, S.A., Redox signaling at invasive microdomains in cancer cells. Free Radic. Biol. Med. 52:2 (2012), 247–256.
    • (2012) Free Radic. Biol. Med. , vol.52 , Issue.2 , pp. 247-256
    • Díaz, B.1    Courtneidge, S.A.2
  • 92
    • 73949101383 scopus 로고    scopus 로고
    • Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation
    • [91] Diaz, B., Shani, G., Pass, I., Anderson, D., Quintavalle, M., Courtneidge, S.A., Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation. Sci. Signal., 2(88), 2009, ra53.
    • (2009) Sci. Signal. , vol.2 , Issue.88 , pp. ra53
    • Diaz, B.1    Shani, G.2    Pass, I.3    Anderson, D.4    Quintavalle, M.5    Courtneidge, S.A.6
  • 93
    • 33749047437 scopus 로고    scopus 로고
    • Localizing NADPH oxidase–derived ROS
    • [92] Ushio-Fukai, M., Localizing NADPH oxidase–derived ROS. Sci.'s STKE, 2006(349), 2006, re8.
    • (2006) Sci.'s STKE , vol.2006 , Issue.349 , pp. re8
    • Ushio-Fukai, M.1
  • 94
    • 57349116981 scopus 로고    scopus 로고
    • Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an n-terminal polybasic region
    • [93] Kawahara, T., Lambeth, J.D., Phosphatidylinositol (4,5)-bisphosphate modulates Nox5 localization via an n-terminal polybasic region. Mol. Biol. Cell 19:10 (2008), 4020–4031.
    • (2008) Mol. Biol. Cell , vol.19 , Issue.10 , pp. 4020-4031
    • Kawahara, T.1    Lambeth, J.D.2
  • 97
    • 44349157885 scopus 로고    scopus 로고
    • Evidence for a superoxide permeability pathway in endosomal membranes
    • [96] Mumbengegwi, D.R., Li, Q., Li, C., Bear, C.E., Engelhardt, J.F., Evidence for a superoxide permeability pathway in endosomal membranes. Mol. Cell. Biol. 28:11 (2008), 3700–3712.
    • (2008) Mol. Cell. Biol. , vol.28 , Issue.11 , pp. 3700-3712
    • Mumbengegwi, D.R.1    Li, Q.2    Li, C.3    Bear, C.E.4    Engelhardt, J.F.5
  • 98
    • 65349113056 scopus 로고    scopus 로고
    • Signaling components of redox active endosomes: the redoxosomes
    • [97] Oakley, F.D., Abbott, D., Li, Q., Engelhardt, J.F., Signaling components of redox active endosomes: the redoxosomes. Antioxid. Redox Signal. 11:6 (2009), 1313–1333.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.6 , pp. 1313-1333
    • Oakley, F.D.1    Abbott, D.2    Li, Q.3    Engelhardt, J.F.4
  • 99
    • 84898959572 scopus 로고    scopus 로고
    • The basic biology of redoxosomes in cytokine-mediated signal transduction and implications for disease-specific therapies
    • [98] Spencer, N.Y., Engelhardt, J.F., The basic biology of redoxosomes in cytokine-mediated signal transduction and implications for disease-specific therapies. Biochemistry 53:10 (2014), 1551–1564.
    • (2014) Biochemistry , vol.53 , Issue.10 , pp. 1551-1564
    • Spencer, N.Y.1    Engelhardt, J.F.2
  • 100
    • 65349157681 scopus 로고    scopus 로고
    • Compartmentalization of redox signaling through NADPH oxidase-derived ROS
    • [99] Ushio-Fukai, M., Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid. Redox Signal. 11:6 (2009), 1289–1299.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.6 , pp. 1289-1299
    • Ushio-Fukai, M.1
  • 101
    • 46249108461 scopus 로고    scopus 로고
    • Regulation of ROS signal transduction by NADPH oxidase 4 localization
    • [100] Chen, K., Kirber, M.T., Xiao, H., Yang, Y., Keaney, J.F. Jr., Regulation of ROS signal transduction by NADPH oxidase 4 localization. J. Cell Biol. 181:7 (2008), 1129–1139.
    • (2008) J. Cell Biol. , vol.181 , Issue.7 , pp. 1129-1139
    • Chen, K.1    Kirber, M.T.2    Xiao, H.3    Yang, Y.4    Keaney, J.F.5
  • 102
    • 70149091965 scopus 로고    scopus 로고
    • Subcellular localization of Nox4 and regulation in diabetes
    • [101] Block, K., Gorin, Y., Abboud, H.E., Subcellular localization of Nox4 and regulation in diabetes. Proc. Natl. Acad. Sci. USA 106:34 (2009), 14385–14390.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.34 , pp. 14385-14390
    • Block, K.1    Gorin, Y.2    Abboud, H.E.3
  • 106
    • 84956964221 scopus 로고    scopus 로고
    • DUOX2 expression is increased in barrett esophagus and cancerous tissues of stomach and colon
    • [105] Qi, R., Zhou, Y., Li, X., Guo, H., Gao, L., Wu, L., Wang, Y., Gao, Q., DUOX2 expression is increased in barrett esophagus and cancerous tissues of stomach and colon. Gastroenterol. Res. Pract., 2016, 2016, 1835684.
    • (2016) Gastroenterol. Res. Pract. , vol.2016 , pp. 1835684
    • Qi, R.1    Zhou, Y.2    Li, X.3    Guo, H.4    Gao, L.5    Wu, L.6    Wang, Y.7    Gao, Q.8
  • 107
    • 79953314094 scopus 로고    scopus 로고
    • NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
    • [106] Wang, R., Dashwood, W.-M., Nian, H., Löhr, C.V., Fischer, K.A., Tsuchiya, N., Nakagama, H., Ashktorab, H., Dashwood, R.H., NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Int. J. Cancer 128:11 (2011), 2581–2590.
    • (2011) Int. J. Cancer , vol.128 , Issue.11 , pp. 2581-2590
    • Wang, R.1    Dashwood, W.-M.2    Nian, H.3    Löhr, C.V.4    Fischer, K.A.5    Tsuchiya, N.6    Nakagama, H.7    Ashktorab, H.8    Dashwood, R.H.9
  • 108
    • 85019480999 scopus 로고    scopus 로고
    • Dual oxidase2 and pancreatic adenocarcinoma: IFN-gamma-mediated dual oxidase2 overexpression results in H2O2-induced, ERK associated up-regulation of HIF-1alpha and VEGF-A
    • [107] Wu, Y., Meitzler, J.L., Antony, S., Juhasz, A., Lu, J., Jiang, G., Liu, H., Hollingshead, M., Haines, D.C., Butcher, D., Panter, M.S., Roy, K., Doroshow, J.H., Dual oxidase2 and pancreatic adenocarcinoma: IFN-gamma-mediated dual oxidase2 overexpression results in H2O2-induced, ERK associated up-regulation of HIF-1alpha and VEGF-A. Oncotarget 7:42 (2016), 68412–68433.
    • (2016) Oncotarget , vol.7 , Issue.42 , pp. 68412-68433
    • Wu, Y.1    Meitzler, J.L.2    Antony, S.3    Juhasz, A.4    Lu, J.5    Jiang, G.6    Liu, H.7    Hollingshead, M.8    Haines, D.C.9    Butcher, D.10    Panter, M.S.11    Roy, K.12    Doroshow, J.H.13
  • 109
    • 84873564101 scopus 로고    scopus 로고
    • Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-gamma and lipopolysaccharide in human pancreatic cancer cell lines
    • (1950)
    • [108] Wu, Y., Lu, J., Antony, S., Juhasz, A., Liu, H., Jiang, G., Meitzler, J.L., Hollingshead, M., Haines, D.C., Butcher, D., Roy, K., Doroshow, J.H., Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-gamma and lipopolysaccharide in human pancreatic cancer cell lines. J. Immunol. 190:4 (2013), 1859–1872 (1950).
    • (2013) J. Immunol. , vol.190 , Issue.4 , pp. 1859-1872
    • Wu, Y.1    Lu, J.2    Antony, S.3    Juhasz, A.4    Liu, H.5    Jiang, G.6    Meitzler, J.L.7    Hollingshead, M.8    Haines, D.C.9    Butcher, D.10    Roy, K.11    Doroshow, J.H.12
  • 110
    • 84874642904 scopus 로고    scopus 로고
    • Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody
    • [109] Wu, Y., Antony, S., Hewitt, S.M., Jiang, G., Yang, S.X., Meitzler, J.L., Juhasz, A., Lu, J., Liu, H., Doroshow, J.H., Roy, K., Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody. Int. J. Oncol. 42:4 (2013), 1229–1238.
    • (2013) Int. J. Oncol. , vol.42 , Issue.4 , pp. 1229-1238
    • Wu, Y.1    Antony, S.2    Hewitt, S.M.3    Jiang, G.4    Yang, S.X.5    Meitzler, J.L.6    Juhasz, A.7    Lu, J.8    Liu, H.9    Doroshow, J.H.10    Roy, K.11
  • 112
    • 84924350333 scopus 로고    scopus 로고
    • Epigenetic silencing of dual oxidase 1 by promoter hypermethylation in human hepatocellular carcinoma
    • [111] Ling, Q., Shi, W., Huang, C., Zheng, J., Cheng, Q., Yu, K., Chen, S., Zhang, H., Li, N., Chen, M., Epigenetic silencing of dual oxidase 1 by promoter hypermethylation in human hepatocellular carcinoma. Am. J. Cancer Res. 4:5 (2014), 508–517.
    • (2014) Am. J. Cancer Res. , vol.4 , Issue.5 , pp. 508-517
    • Ling, Q.1    Shi, W.2    Huang, C.3    Zheng, J.4    Cheng, Q.5    Yu, K.6    Chen, S.7    Zhang, H.8    Li, N.9    Chen, M.10
  • 116
    • 67650917886 scopus 로고    scopus 로고
    • Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues
    • [115] Juhasz, A., Ge, Y., Markel, S., Chiu, A., Matsumoto, L., van Balgooy, J., Roy, K., Doroshow, J.H., Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues. Free Radic. Res. 43:6 (2009), 523–532.
    • (2009) Free Radic. Res. , vol.43 , Issue.6 , pp. 523-532
    • Juhasz, A.1    Ge, Y.2    Markel, S.3    Chiu, A.4    Matsumoto, L.5    van Balgooy, J.6    Roy, K.7    Doroshow, J.H.8
  • 117
    • 84901036297 scopus 로고    scopus 로고
    • Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling
    • [116] De Deken, X., Corvilain, B., Dumont, J.E., Miot, F., Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling. Antioxid. Redox Signal. 20:17 (2014), 2776–2793.
    • (2014) Antioxid. Redox Signal. , vol.20 , Issue.17 , pp. 2776-2793
    • De Deken, X.1    Corvilain, B.2    Dumont, J.E.3    Miot, F.4
  • 120
    • 84924942012 scopus 로고    scopus 로고
    • The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release
    • [119] Ueyama, T., Sakuma, M., Ninoyu, Y., Hamada, T., Dupuy, C., Geiszt, M., Leto, T.L., Saito, N., The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release. J. Biol. Chem. 290:10 (2015), 6495–6506.
    • (2015) J. Biol. Chem. , vol.290 , Issue.10 , pp. 6495-6506
    • Ueyama, T.1    Sakuma, M.2    Ninoyu, Y.3    Hamada, T.4    Dupuy, C.5    Geiszt, M.6    Leto, T.L.7    Saito, N.8
  • 121
    • 33745821178 scopus 로고    scopus 로고
    • Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent
    • [120] Grasberger, H., Refetoff, S., Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent. J. Biol. Chem. 281:27 (2006), 18269–18272.
    • (2006) J. Biol. Chem. , vol.281 , Issue.27 , pp. 18269-18272
    • Grasberger, H.1    Refetoff, S.2
  • 122
    • 66849111512 scopus 로고    scopus 로고
    • Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells
    • [121] Luxen, S., Noack, D., Frausto, M., Davanture, S., Torbett, B.E., Knaus, U.G., Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells. J. Cell Sci. 122:Pt 8 (2009), 1238–1247.
    • (2009) J. Cell Sci. , vol.122 , pp. 1238-1247
    • Luxen, S.1    Noack, D.2    Frausto, M.3    Davanture, S.4    Torbett, B.E.5    Knaus, U.G.6
  • 123
    • 0033601327 scopus 로고    scopus 로고
    • A. virion, purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas
    • [122] Dupuy, C., Ohayon, R., Valent, A., Noel-Hudson, M.S., Deme, D., A. virion, purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas. J. Biol. Chem. 274:52 (1999), 37265–37269.
    • (1999) J. Biol. Chem. , vol.274 , Issue.52 , pp. 37265-37269
    • Dupuy, C.1    Ohayon, R.2    Valent, A.3    Noel-Hudson, M.S.4    Deme, D.5
  • 125
    • 33745209498 scopus 로고    scopus 로고
    • NADPH oxidases: new kids on the block
    • [124] Geiszt, M., NADPH oxidases: new kids on the block. Cardiovasc. Res. 71:2 (2006), 289–299.
    • (2006) Cardiovasc. Res. , vol.71 , Issue.2 , pp. 289-299
    • Geiszt, M.1
  • 126
    • 33750926794 scopus 로고    scopus 로고
    • Role of Nox family NADPH oxidases in host defense
    • [125] Leto, T.L., Geiszt, M., Role of Nox family NADPH oxidases in host defense. Antioxid. Redox Signal. 8:9–10 (2006), 1549–1561.
    • (2006) Antioxid. Redox Signal. , vol.8 , Issue.9-10 , pp. 1549-1561
    • Leto, T.L.1    Geiszt, M.2
  • 127
    • 84895919381 scopus 로고    scopus 로고
    • Hydrogen peroxide generated by DUOX1 regulates the expression levels of specific differentiation markers in normal human keratinocytes
    • [126] Choi, H., Park, J.Y., Kim, H.J., Noh, M., Ueyama, T., Bae, Y., Lee, T.R., Shin, D.W., Hydrogen peroxide generated by DUOX1 regulates the expression levels of specific differentiation markers in normal human keratinocytes. J. Dermatol. Sci. 74:1 (2014), 56–63.
    • (2014) J. Dermatol. Sci. , vol.74 , Issue.1 , pp. 56-63
    • Choi, H.1    Park, J.Y.2    Kim, H.J.3    Noh, M.4    Ueyama, T.5    Bae, Y.6    Lee, T.R.7    Shin, D.W.8
  • 130
    • 84924929671 scopus 로고    scopus 로고
    • Lung epithelial NOX/DUOX and respiratory virus infections
    • (1979)
    • [129] Grandvaux, N., Mariani, M., Fink, K., Lung epithelial NOX/DUOX and respiratory virus infections. Clin. Sci. 128:6 (2015), 337–347 (1979).
    • (2015) Clin. Sci. , vol.128 , Issue.6 , pp. 337-347
    • Grandvaux, N.1    Mariani, M.2    Fink, K.3
  • 131
    • 24044451233 scopus 로고    scopus 로고
    • Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium
    • [130] Harper, R.W., Xu, C., Eiserich, J.P., Chen, Y., Kao, C.Y., Thai, P., Setiadi, H., Wu, R., Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium. FEBS Lett. 579:21 (2005), 4911–4917.
    • (2005) FEBS Lett. , vol.579 , Issue.21 , pp. 4911-4917
    • Harper, R.W.1    Xu, C.2    Eiserich, J.P.3    Chen, Y.4    Kao, C.Y.5    Thai, P.6    Setiadi, H.7    Wu, R.8
  • 132
    • 45549088074 scopus 로고    scopus 로고
    • Dual role of NOX2 in respiratory syncytial virus- and sendai virus-induced activation of NF-kappab in airway epithelial cells
    • (1950)
    • [131] Fink, K., Duval, A., Martel, A., Soucy-Faulkner, A., Grandvaux, N., Dual role of NOX2 in respiratory syncytial virus- and sendai virus-induced activation of NF-kappab in airway epithelial cells. J. Immunol. 180:10 (2008), 6911–6922 (1950).
    • (2008) J. Immunol. , vol.180 , Issue.10 , pp. 6911-6922
    • Fink, K.1    Duval, A.2    Martel, A.3    Soucy-Faulkner, A.4    Grandvaux, N.5
  • 133
    • 84877101652 scopus 로고    scopus 로고
    • IFN[beta]/TNF[alpha] synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response
    • [132] Fink, K., Martin, L., Mukawera, E., Chartier, S., De Deken, X., Brochiero, E., Miot, F., Grandvaux, N., IFN[beta]/TNF[alpha] synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response. Cell Res. 23:5 (2013), 673–690.
    • (2013) Cell Res. , vol.23 , Issue.5 , pp. 673-690
    • Fink, K.1    Martin, L.2    Mukawera, E.3    Chartier, S.4    De Deken, X.5    Brochiero, E.6    Miot, F.7    Grandvaux, N.8
  • 135
    • 84872548417 scopus 로고    scopus 로고
    • ATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17
    • [134] Sham, D., Wesley, U.V., Hristova, M., van der Vliet, A., ATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17. PLoS One, 8(1), 2013, e54391.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e54391
    • Sham, D.1    Wesley, U.V.2    Hristova, M.3    van der Vliet, A.4
  • 136
    • 84892727407 scopus 로고    scopus 로고
    • Hydrogen peroxide as a damage signal in tissue injury and inflammation: murderer, mediator, or messenger?
    • [135] van der Vliet, A., Janssen-Heininger, Y.M.W., Hydrogen peroxide as a damage signal in tissue injury and inflammation: murderer, mediator, or messenger?. J. Cell. Biochem. 115:3 (2014), 427–435.
    • (2014) J. Cell. Biochem. , vol.115 , Issue.3 , pp. 427-435
    • van der Vliet, A.1    Janssen-Heininger, Y.M.W.2
  • 137
    • 84875229002 scopus 로고    scopus 로고
    • Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release
    • [136] Razzell, W., Evans, Iwan R., Martin, P., Wood, W., Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release. Curr. Biol. 23:5 (2013), 424–429.
    • (2013) Curr. Biol. , vol.23 , Issue.5 , pp. 424-429
    • Razzell, W.1    Evans, I.R.2    Martin, P.3    Wood, W.4
  • 138
    • 84875426064 scopus 로고    scopus 로고
    • The role of transcription-independent damage signals in the initiation of epithelial wound healing
    • [137] Cordeiro, J.V., Jacinto, A., The role of transcription-independent damage signals in the initiation of epithelial wound healing. Nat. Rev. Mol. Cell Biol. 14:4 (2013), 249–262.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , Issue.4 , pp. 249-262
    • Cordeiro, J.V.1    Jacinto, A.2
  • 139
  • 140
    • 34047267984 scopus 로고    scopus 로고
    • Airway epithelial cell migration and wound repair by ATP-mediated activation of dual oxidase 1
    • [139] Wesley, U.V., Bove, P.F., Hristova, M., McCarthy, S., van der Vliet, A., Airway epithelial cell migration and wound repair by ATP-mediated activation of dual oxidase 1. J. Biol. Chem. 282:5 (2007), 3213–3220.
    • (2007) J. Biol. Chem. , vol.282 , Issue.5 , pp. 3213-3220
    • Wesley, U.V.1    Bove, P.F.2    Hristova, M.3    McCarthy, S.4    van der Vliet, A.5
  • 142
    • 79955036320 scopus 로고    scopus 로고
    • Dual oxidase 1 induced by Th2 cytokines promotes STAT6 phosphorylation via oxidative inactivation of protein tyrosine phosphatase 1B in human epidermal keratinocytes
    • (1950)
    • [141] Hirakawa, S., Saito, R., Ohara, H., Okuyama, R., Aiba, S., Dual oxidase 1 induced by Th2 cytokines promotes STAT6 phosphorylation via oxidative inactivation of protein tyrosine phosphatase 1B in human epidermal keratinocytes. J. Immunol. 186:8 (2011), 4762–4770 (1950).
    • (2011) J. Immunol. , vol.186 , Issue.8 , pp. 4762-4770
    • Hirakawa, S.1    Saito, R.2    Ohara, H.3    Okuyama, R.4    Aiba, S.5
  • 143
    • 84922495975 scopus 로고    scopus 로고
    • Duox1-derived H2O2 modulates Cxcl8 expression and neutrophil recruitment via JNK/c-JUN/AP-1 signaling and chromatin modifications
    • (1950)
    • [142] de Oliveira, S., Boudinot, P., Calado, A., Mulero, V., Duox1-derived H2O2 modulates Cxcl8 expression and neutrophil recruitment via JNK/c-JUN/AP-1 signaling and chromatin modifications. J. Immunol. 194:4 (2015), 1523–1533 (1950).
    • (2015) J. Immunol. , vol.194 , Issue.4 , pp. 1523-1533
    • de Oliveira, S.1    Boudinot, P.2    Calado, A.3    Mulero, V.4
  • 148
    • 77956635663 scopus 로고    scopus 로고
    • The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling
    • [147] Kwon, J., Shatynski, K.E., Chen, H., Morand, S., de Deken, X., Miot, F., Leto, T.L., Williams, M.S., The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling. Sci. Signal., 3(133), 2010, ra59.
    • (2010) Sci. Signal. , vol.3 , Issue.133 , pp. ra59
    • Kwon, J.1    Shatynski, K.E.2    Chen, H.3    Morand, S.4    de Deken, X.5    Miot, F.6    Leto, T.L.7    Williams, M.S.8
  • 149
    • 84993967413 scopus 로고    scopus 로고
    • The NADPH oxidases DUOX1 and NOX2 play distinct roles in redox regulation of epidermal growth factor receptor signaling
    • [148] Heppner, D.E., Hristova, M., Dustin, C.M., Danyal, K., Habibovic, A., van der Vliet, A., The NADPH oxidases DUOX1 and NOX2 play distinct roles in redox regulation of epidermal growth factor receptor signaling. J. Biol. Chem. 291:44 (2016), 23282–23293.
    • (2016) J. Biol. Chem. , vol.291 , Issue.44 , pp. 23282-23293
    • Heppner, D.E.1    Hristova, M.2    Dustin, C.M.3    Danyal, K.4    Habibovic, A.5    van der Vliet, A.6
  • 150
    • 84880298785 scopus 로고    scopus 로고
    • H2O2: a chemoattractant?
    • [149] Enyedi, B., Niethammer, P., H2O2: a chemoattractant?. Methods Enzymol. 528 (2013), 237–255.
    • (2013) Methods Enzymol. , vol.528 , pp. 237-255
    • Enyedi, B.1    Niethammer, P.2
  • 151
    • 67649255876 scopus 로고    scopus 로고
    • A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
    • [150] Niethammer, P., Grabher, C., Look, A.T., Mitchison, T.J., A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 459:7249 (2009), 996–999.
    • (2009) Nature , vol.459 , Issue.7249 , pp. 996-999
    • Niethammer, P.1    Grabher, C.2    Look, A.T.3    Mitchison, T.J.4
  • 152
    • 34547852400 scopus 로고    scopus 로고
    • NOX family NADPH oxidases: not just in mammals
    • [151] Bedard, K., Lardy, B., Krause, K.-H., NOX family NADPH oxidases: not just in mammals. Biochimie 89:9 (2007), 1107–1112.
    • (2007) Biochimie , vol.89 , Issue.9 , pp. 1107-1112
    • Bedard, K.1    Lardy, B.2    Krause, K.-H.3
  • 153
    • 84882709450 scopus 로고    scopus 로고
    • Gut homeostasis in a microbial world: insights from Drosophila melanogaster
    • [152] Buchon, N., Broderick, N.A., Lemaitre, B., Gut homeostasis in a microbial world: insights from Drosophila melanogaster. Nat. Rev. Microbiol. 11:9 (2013), 615–626.
    • (2013) Nat. Rev. Microbiol. , vol.11 , Issue.9 , pp. 615-626
    • Buchon, N.1    Broderick, N.A.2    Lemaitre, B.3
  • 154
    • 0035202331 scopus 로고    scopus 로고
    • A unique combination of transcription factors controls differentiation of thyroid cells
    • [153] Damante, G., Tell, G., Di Lauro, R., A unique combination of transcription factors controls differentiation of thyroid cells. Progress. Nucleic Acid. Res. Mol. Biol. 66 (2001), 307–356.
    • (2001) Progress. Nucleic Acid. Res. Mol. Biol. , vol.66 , pp. 307-356
    • Damante, G.1    Tell, G.2    Di Lauro, R.3
  • 158
    • 84866978507 scopus 로고    scopus 로고
    • Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia
    • [157] Xu, C., Linderholm, A., Grasberger, H., Harper, R.W., Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia. Am. J. Respir. Cell Mol. Biol. 47:4 (2012), 484–490.
    • (2012) Am. J. Respir. Cell Mol. Biol. , vol.47 , Issue.4 , pp. 484-490
    • Xu, C.1    Linderholm, A.2    Grasberger, H.3    Harper, R.W.4
  • 159
    • 84924929671 scopus 로고    scopus 로고
    • Lung epithelial NOX/DUOX and respiratory virus infections
    • (1979)
    • [158] Grandvaux, N., Mariani, M., Fink, K., Lung epithelial NOX/DUOX and respiratory virus infections. Clin. Sci. 128:6 (2015), 337–347 (1979).
    • (2015) Clin. Sci. , vol.128 , Issue.6 , pp. 337-347
    • Grandvaux, N.1    Mariani, M.2    Fink, K.3
  • 160
    • 70349354334 scopus 로고    scopus 로고
    • Mechanisms and function of DUOX in epithelia of the lung
    • [159] Fischer, H., Mechanisms and function of DUOX in epithelia of the lung. Antioxid. Redox Signal. 11:10 (2009), 2453–2465.
    • (2009) Antioxid. Redox Signal. , vol.11 , Issue.10 , pp. 2453-2465
    • Fischer, H.1
  • 162
    • 79953303217 scopus 로고    scopus 로고
    • Up-regulation and sustained activation of Stat1 Are essential for interferon-γ (IFN-γ)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines
    • [161] Wu, Y., Antony, S., Juhasz, A., Lu, J., Ge, Y., Jiang, G., Roy, K., Doroshow, J.H., Up-regulation and sustained activation of Stat1 Are essential for interferon-γ (IFN-γ)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines. J. Biol. Chem. 286:14 (2011), 12245–12256.
    • (2011) J. Biol. Chem. , vol.286 , Issue.14 , pp. 12245-12256
    • Wu, Y.1    Antony, S.2    Juhasz, A.3    Lu, J.4    Ge, Y.5    Jiang, G.6    Roy, K.7    Doroshow, J.H.8
  • 164
    • 33845212729 scopus 로고    scopus 로고
    • Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment
    • (48-48)
    • [163] Lewis, A.M., Varghese, S., Xu, H., Alexander, H.R., Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment. J. Transl. Med., 4, 2006 (48-48).
    • (2006) J. Transl. Med. , vol.4
    • Lewis, A.M.1    Varghese, S.2    Xu, H.3    Alexander, H.R.4
  • 165
    • 84869875206 scopus 로고    scopus 로고
    • IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation
    • [164] Li, Y., Wang, L., Pappan, L., Galliher-Beckley, A., Shi, J., IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation. Mol. Cancer, 11(1), 2012, 87.
    • (2012) Mol. Cancer , vol.11 , Issue.1 , pp. 87
    • Li, Y.1    Wang, L.2    Pappan, L.3    Galliher-Beckley, A.4    Shi, J.5
  • 166
    • 84897945579 scopus 로고    scopus 로고
    • The role IL-1 in tumor-mediated angiogenesis
    • [165] Voronov, E., Carmi, Y., Apte, R., The role IL-1 in tumor-mediated angiogenesis. Front. Physiol., 5(114), 2014.
    • (2014) Front. Physiol. , vol.5 , Issue.114
    • Voronov, E.1    Carmi, Y.2    Apte, R.3
  • 171
    • 84938985048 scopus 로고    scopus 로고
    • Targeting of IL-4 and IL-13 receptors for cancer therapy
    • [170] Suzuki, A., Leland, P., Joshi, B.H., Puri, R.K., Targeting of IL-4 and IL-13 receptors for cancer therapy. Cytokine 75:1 (2015), 79–88.
    • (2015) Cytokine , vol.75 , Issue.1 , pp. 79-88
    • Suzuki, A.1    Leland, P.2    Joshi, B.H.3    Puri, R.K.4
  • 172
    • 84930440762 scopus 로고    scopus 로고
    • Aberrant methylation patterns in cancer: a clinical view
    • [171] Paska, A.V., Hudler, P., Aberrant methylation patterns in cancer: a clinical view. Biochem. Med. 25:2 (2015), 161–176.
    • (2015) Biochem. Med. , vol.25 , Issue.2 , pp. 161-176
    • Paska, A.V.1    Hudler, P.2
  • 173
    • 84970967206 scopus 로고    scopus 로고
    • Beyond transcription factors: how oncogenic signalling reshapes the epigenetic landscape
    • [172] Liu, F., Wang, L., Perna, F., Nimer, S.D., Beyond transcription factors: how oncogenic signalling reshapes the epigenetic landscape. Nat. Rev. Cancer 16:6 (2016), 359–372.
    • (2016) Nat. Rev. Cancer , vol.16 , Issue.6 , pp. 359-372
    • Liu, F.1    Wang, L.2    Perna, F.3    Nimer, S.D.4
  • 174
    • 84863621527 scopus 로고    scopus 로고
    • Cancer epigenetics: from mechanism to therapy, Cell
    • [173] Mark A. Dawson, T. Kouzarides, Cancer epigenetics: from mechanism to therapy, Cell 150 (1) (2012) 12–27.
    • (2012) , vol.150 , Issue.1 , pp. 12-27
    • Mark, A.1    Dawson, T.K.2
  • 175
    • 84961218734 scopus 로고    scopus 로고
    • Epigenetic modulators, modifiers and mediators in cancer aetiology and progression
    • [174] Feinberg, A.P., Koldobskiy, M.A., Gondor, A., Epigenetic modulators, modifiers and mediators in cancer aetiology and progression. Nat. Rev. Genet. 17:5 (2016), 284–299.
    • (2016) Nat. Rev. Genet. , vol.17 , Issue.5 , pp. 284-299
    • Feinberg, A.P.1    Koldobskiy, M.A.2    Gondor, A.3
  • 177
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • [176] Jones, P.A., Baylin, S.B., The epigenomics of cancer. Cell 128:4 (2007), 683–692.
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 178
    • 84912099856 scopus 로고    scopus 로고
    • RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation
    • [177] Wu, B.K., Mei, S.C., Brenner, C., RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylation. Cell Cycle 13:20 (2014), 3222–3231.
    • (2014) Cell Cycle , vol.13 , Issue.20 , pp. 3222-3231
    • Wu, B.K.1    Mei, S.C.2    Brenner, C.3
  • 180
    • 77249099223 scopus 로고    scopus 로고
    • CpG methylation attenuates Sp1 and Sp3 binding to the human extracellular superoxide dismutase promoter and regulates its cell-specific expression
    • [179] Zelko, I.N., Mueller, M.R., Folz, R.J., CpG methylation attenuates Sp1 and Sp3 binding to the human extracellular superoxide dismutase promoter and regulates its cell-specific expression. Free Radic. Biol. Med. 48:7 (2010), 895–904.
    • (2010) Free Radic. Biol. Med. , vol.48 , Issue.7 , pp. 895-904
    • Zelko, I.N.1    Mueller, M.R.2    Folz, R.J.3
  • 181
    • 84895874347 scopus 로고    scopus 로고
    • A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-beta
    • [180] Bai, G., Hock, T.D., Logsdon, N., Zhou, Y., Thannickal, V.J., A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-beta. Gene 540:1 (2014), 62–67.
    • (2014) Gene , vol.540 , Issue.1 , pp. 62-67
    • Bai, G.1    Hock, T.D.2    Logsdon, N.3    Zhou, Y.4    Thannickal, V.J.5
  • 182
    • 84920742368 scopus 로고    scopus 로고
    • Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence
    • [181] Sanders, Y.Y., Liu, H., Liu, G., Thannickal, V.J., Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence. Free Radic. Biol. Med. 79 (2015), 197–205.
    • (2015) Free Radic. Biol. Med. , vol.79 , pp. 197-205
    • Sanders, Y.Y.1    Liu, H.2    Liu, G.3    Thannickal, V.J.4
  • 183
    • 84963612049 scopus 로고    scopus 로고
    • Combining epigenetic and immunotherapy to combat cancer
    • [182] Chiappinelli, K.B., Zahnow, C.A., Ahuja, N., Baylin, S.B., Combining epigenetic and immunotherapy to combat cancer. Cancer Res. 76:7 (2016), 1683–1689.
    • (2016) Cancer Res. , vol.76 , Issue.7 , pp. 1683-1689
    • Chiappinelli, K.B.1    Zahnow, C.A.2    Ahuja, N.3    Baylin, S.B.4
  • 184
    • 84963644301 scopus 로고    scopus 로고
    • Low-dose DNA-demethylating agent enhances the chemosensitivity of cancer cells by targeting cancer stem cells via the upregulation of microRNA-497
    • [183] Liu, L., Chen, L., Wu, X., Li, X., Song, Y., Mei, Q., Nie, J., Han, W., Low-dose DNA-demethylating agent enhances the chemosensitivity of cancer cells by targeting cancer stem cells via the upregulation of microRNA-497. J. Cancer Res. Clin. Oncol. 142:7 (2016), 1431–1439.
    • (2016) J. Cancer Res. Clin. Oncol. , vol.142 , Issue.7 , pp. 1431-1439
    • Liu, L.1    Chen, L.2    Wu, X.3    Li, X.4    Song, Y.5    Mei, Q.6    Nie, J.7    Han, W.8
  • 185
    • 26044476923 scopus 로고    scopus 로고
    • Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells
    • [184] Qiu, Y.-Y., Mirkin, B.L., Dwivedi, R.S., Inhibition of DNA methyltransferase reverses cisplatin induced drug resistance in murine neuroblastoma cells. Cancer Detect. Prev. 29:5 (2005), 456–463.
    • (2005) Cancer Detect. Prev. , vol.29 , Issue.5 , pp. 456-463
    • Qiu, Y.-Y.1    Mirkin, B.L.2    Dwivedi, R.S.3
  • 187
    • 53349163022 scopus 로고    scopus 로고
    • The role of dna hypermethylation and demethylation in cancer and cancer therapy
    • [186] Szyf, M., The role of dna hypermethylation and demethylation in cancer and cancer therapy. Curr. Oncol. 15:2 (2008), 72–75.
    • (2008) Curr. Oncol. , vol.15 , Issue.2 , pp. 72-75
    • Szyf, M.1
  • 188
    • 84960345039 scopus 로고    scopus 로고
    • Expanding roles of superoxide dismutases in cell regulation and cancer
    • [187] Che, M., Wang, R., Li, X., Wang, H.Y., Zheng, X.F., Expanding roles of superoxide dismutases in cell regulation and cancer. Drug Discov. Today 21:1 (2016), 143–149.
    • (2016) Drug Discov. Today , vol.21 , Issue.1 , pp. 143-149
    • Che, M.1    Wang, R.2    Li, X.3    Wang, H.Y.4    Zheng, X.F.5
  • 189
    • 84973303615 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase: growth promoter or tumor suppressor?
    • [188] Laukkanen, M.O., Extracellular superoxide dismutase: growth promoter or tumor suppressor?. Oxid. Med. Cell. Longev., 2016, 2016, 3612589.
    • (2016) Oxid. Med. Cell. Longev. , vol.2016 , pp. 3612589
    • Laukkanen, M.O.1
  • 191
    • 84892665190 scopus 로고    scopus 로고
    • Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis
    • [190] Teoh-Fitzgerald, M.L., Fitzgerald, M.P., Zhong, W., Askeland, R.W., Domann, F.E., Epigenetic reprogramming governs EcSOD expression during human mammary epithelial cell differentiation, tumorigenesis and metastasis. Oncogene 33:3 (2014), 358–368.
    • (2014) Oncogene , vol.33 , Issue.3 , pp. 358-368
    • Teoh-Fitzgerald, M.L.1    Fitzgerald, M.P.2    Zhong, W.3    Askeland, R.W.4    Domann, F.E.5
  • 192
    • 84856017594 scopus 로고    scopus 로고
    • Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis
    • [191] Teoh-Fitzgerald, M.L., Fitzgerald, M.P., Jensen, T.J., Futscher, B.W., Domann, F.E., Genetic and epigenetic inactivation of extracellular superoxide dismutase promotes an invasive phenotype in human lung cancer by disrupting ECM homeostasis. Mol. Cancer Res.: MCR 10:1 (2012), 40–51.
    • (2012) Mol. Cancer Res.: MCR , vol.10 , Issue.1 , pp. 40-51
    • Teoh-Fitzgerald, M.L.1    Fitzgerald, M.P.2    Jensen, T.J.3    Futscher, B.W.4    Domann, F.E.5
  • 193
    • 68049143319 scopus 로고    scopus 로고
    • Overexpression of extracellular superoxide dismutase attenuates heparanase expression and inhibits breast carcinoma cell growth and invasion
    • [192] Teoh, M.L., Fitzgerald, M.P., Oberley, L.W., Domann, F.E., Overexpression of extracellular superoxide dismutase attenuates heparanase expression and inhibits breast carcinoma cell growth and invasion. Cancer Res. 69:15 (2009), 6355–6363.
    • (2009) Cancer Res. , vol.69 , Issue.15 , pp. 6355-6363
    • Teoh, M.L.1    Fitzgerald, M.P.2    Oberley, L.W.3    Domann, F.E.4
  • 194
    • 0035962631 scopus 로고    scopus 로고
    • DNA methylation, methyltransferases, and cancer
    • [193] Robertson, K.D., DNA methylation, methyltransferases, and cancer. Oncogene 20:24 (2001), 3139–3155.
    • (2001) Oncogene , vol.20 , Issue.24 , pp. 3139-3155
    • Robertson, K.D.1
  • 196
    • 84922272549 scopus 로고    scopus 로고
    • DNA methylation pattern alterations in carcinogenesis
    • [195] Wu, Q., Ni, X., ROS-mediated, DNA methylation pattern alterations in carcinogenesis. Curr. Drug Targets 16:1 (2015), 13–19.
    • (2015) Curr. Drug Targets , vol.16 , Issue.1 , pp. 13-19
    • Wu, Q.1    Ni, X.2    ROS-mediated3
  • 197
    • 84908265816 scopus 로고    scopus 로고
    • Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
    • [196] Falkenberg, K.J., Johnstone, R.W., Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat. Rev. Drug Discov. 13:9 (2014), 673–691.
    • (2014) Nat. Rev. Drug Discov. , vol.13 , Issue.9 , pp. 673-691
    • Falkenberg, K.J.1    Johnstone, R.W.2
  • 199
    • 84886860116 scopus 로고    scopus 로고
    • TET enzymes, TDG and the dynamics of DNA demethylation
    • [198] Kohli, R.M., Zhang, Y., TET enzymes, TDG and the dynamics of DNA demethylation. Nature 502:7472 (2013), 472–479.
    • (2013) Nature , vol.502 , Issue.7472 , pp. 472-479
    • Kohli, R.M.1    Zhang, Y.2
  • 200
    • 84948381421 scopus 로고    scopus 로고
    • TET family of dioxygenases: crucial roles and underlying mechanisms
    • [199] Li, D., Guo, B., Wu, H., Tan, L., Lu, Q., TET family of dioxygenases: crucial roles and underlying mechanisms. Cytogenet. Genome Res. 146:3 (2015), 171–180.
    • (2015) Cytogenet. Genome Res. , vol.146 , Issue.3 , pp. 171-180
    • Li, D.1    Guo, B.2    Wu, H.3    Tan, L.4    Lu, Q.5
  • 201
    • 84915798721 scopus 로고    scopus 로고
    • Suppression of TET1-dependent DNA demethylation is essential for KRAS-mediated transformation
    • [200] Wu, B.K., Brenner, C., Suppression of TET1-dependent DNA demethylation is essential for KRAS-mediated transformation. Cell Rep. 9:5 (2014), 1827–1840.
    • (2014) Cell Rep. , vol.9 , Issue.5 , pp. 1827-1840
    • Wu, B.K.1    Brenner, C.2
  • 206
    • 84877693964 scopus 로고    scopus 로고
    • Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine
    • [205] Minor, E.A., Court, B.L., Young, J.I., Wang, G., Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine. J. Biol. Chem. 288:19 (2013), 13669–13674.
    • (2013) J. Biol. Chem. , vol.288 , Issue.19 , pp. 13669-13674
    • Minor, E.A.1    Court, B.L.2    Young, J.I.3    Wang, G.4
  • 207
    • 84919361095 scopus 로고    scopus 로고
    • The deep end of the metabolite pool: influences on epigenetic regulatory mechanisms in cancer
    • [206] Nordgren, K.K., Skildum, A.J., The deep end of the metabolite pool: influences on epigenetic regulatory mechanisms in cancer. Eur. J. Clin. Invest. 45:Suppl. 1 (2015), S9–S15.
    • (2015) Eur. J. Clin. Invest. , vol.45 , pp. S9-S15
    • Nordgren, K.K.1    Skildum, A.J.2
  • 208
    • 84964855350 scopus 로고    scopus 로고
    • Oncometabolites: unconventional triggers of oncogenic signalling cascades
    • [207] Sciacovelli, M., Frezza, C., Oncometabolites: unconventional triggers of oncogenic signalling cascades. Free Radic. Biol. Med. 100 (2016), 175–181.
    • (2016) Free Radic. Biol. Med. , vol.100 , pp. 175-181
    • Sciacovelli, M.1    Frezza, C.2
  • 209
    • 84909987959 scopus 로고    scopus 로고
    • Prognostic significance of epithelial-mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray
    • [208] Nitta, T., Mitsuhashi, T., Hatanaka, Y., Miyamoto, M., Oba, K., Tsuchikawa, T., Suzuki, Y., Hatanaka, K.C., Hirano, S., Matsuno, Y., Prognostic significance of epithelial-mesenchymal transition-related markers in extrahepatic cholangiocarcinoma: comprehensive immunohistochemical study using a tissue microarray. Br. J. Cancer 111:7 (2014), 1363–1372.
    • (2014) Br. J. Cancer , vol.111 , Issue.7 , pp. 1363-1372
    • Nitta, T.1    Mitsuhashi, T.2    Hatanaka, Y.3    Miyamoto, M.4    Oba, K.5    Tsuchikawa, T.6    Suzuki, Y.7    Hatanaka, K.C.8    Hirano, S.9    Matsuno, Y.10
  • 211
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
    • [210] Singh, A., Settleman, J., EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 29:34 (2010), 4741–4751.
    • (2010) Oncogene , vol.29 , Issue.34 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 212
  • 215
    • 0037064048 scopus 로고    scopus 로고
    • The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core
    • [214] He, C., Hobert, M., Friend, L., Carlin, C., The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core. J. Biol. Chem. 277:41 (2002), 38284–38293.
    • (2002) J. Biol. Chem. , vol.277 , Issue.41 , pp. 38284-38293
    • He, C.1    Hobert, M.2    Friend, L.3    Carlin, C.4
  • 216
    • 84894122053 scopus 로고    scopus 로고
    • Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells
    • [215] Singh, B., Coffey, R.J., Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells. Annu. Rev. Physiol. 76 (2014), 275–300.
    • (2014) Annu. Rev. Physiol. , vol.76 , pp. 275-300
    • Singh, B.1    Coffey, R.J.2
  • 217
    • 0037456842 scopus 로고    scopus 로고
    • Segregation of receptor and ligand regulates activation of epithelial growth factor receptor
    • [216] Vermeer, P.D., Einwalter, L.A., Moninger, T.O., Rokhlina, T., Kern, J.A., Zabner, J., Welsh, M.J., Segregation of receptor and ligand regulates activation of epithelial growth factor receptor. Nature 422:6929 (2003), 322–326.
    • (2003) Nature , vol.422 , Issue.6929 , pp. 322-326
    • Vermeer, P.D.1    Einwalter, L.A.2    Moninger, T.O.3    Rokhlina, T.4    Kern, J.A.5    Zabner, J.6    Welsh, M.J.7
  • 218
    • 2442552774 scopus 로고    scopus 로고
    • E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases
    • [217] Qian, X., Karpova, T., Sheppard, A.M., McNally, J., Lowy, D.R., E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases. EMBO J. 23:8 (2004), 1739–1748.
    • (2004) EMBO J. , vol.23 , Issue.8 , pp. 1739-1748
    • Qian, X.1    Karpova, T.2    Sheppard, A.M.3    McNally, J.4    Lowy, D.R.5
  • 219
    • 84876684957 scopus 로고    scopus 로고
    • Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12
    • [218] Su, B., Gao, L., Meng, F., Guo, L.W., Rothschild, J., Gelman, I.H., Adhesion-mediated cytoskeletal remodeling is controlled by the direct scaffolding of Src from FAK complexes to lipid rafts by SSeCKS/AKAP12. Oncogene 32:16 (2013), 2016–2026.
    • (2013) Oncogene , vol.32 , Issue.16 , pp. 2016-2026
    • Su, B.1    Gao, L.2    Meng, F.3    Guo, L.W.4    Rothschild, J.5    Gelman, I.H.6
  • 220
    • 33745828702 scopus 로고    scopus 로고
    • EGF–ERBB signalling: towards the systems level
    • [219] Citri, A., Yarden, Y., EGF–ERBB signalling: towards the systems level. Nat. Rev. Mol. Cell Biol. 7:7 (2006), 505–516.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , Issue.7 , pp. 505-516
    • Citri, A.1    Yarden, Y.2
  • 221
    • 84864367360 scopus 로고    scopus 로고
    • The ERBB network: at last, cancer therapy meets systems biology
    • [220] Yarden, Y., Pines, G., The ERBB network: at last, cancer therapy meets systems biology. Nat. Rev. Cancer 12:8 (2012), 553–563.
    • (2012) Nat. Rev. Cancer , vol.12 , Issue.8 , pp. 553-563
    • Yarden, Y.1    Pines, G.2
  • 222
    • 77956178360 scopus 로고    scopus 로고
    • EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
    • [221] Singh, A., Settleman, J., EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 29:34 (2010), 4741–4751.
    • (2010) Oncogene , vol.29 , Issue.34 , pp. 4741-4751
    • Singh, A.1    Settleman, J.2
  • 223
    • 84882840901 scopus 로고    scopus 로고
    • Epidermal growth factor receptor targeting in cancer: a review of trends and strategies
    • [222] Yewale, C., Baradia, D., Vhora, I., Patil, S., Misra, A., Epidermal growth factor receptor targeting in cancer: a review of trends and strategies. Biomaterials 34:34 (2013), 8690–8707.
    • (2013) Biomaterials , vol.34 , Issue.34 , pp. 8690-8707
    • Yewale, C.1    Baradia, D.2    Vhora, I.3    Patil, S.4    Misra, A.5
  • 224
    • 0036500831 scopus 로고    scopus 로고
    • Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy
    • [223] Herbst, R.S., Shin, D.M., Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy. Cancer 94:5 (2002), 1593–1611.
    • (2002) Cancer , vol.94 , Issue.5 , pp. 1593-1611
    • Herbst, R.S.1    Shin, D.M.2
  • 225
    • 84887497121 scopus 로고    scopus 로고
    • The quest to overcome resistance to EGFR-targeted therapies in cancer
    • [224] Chong, C.R., Janne, P.A., The quest to overcome resistance to EGFR-targeted therapies in cancer. Nat. Med. 19:11 (2013), 1389–1400.
    • (2013) Nat. Med. , vol.19 , Issue.11 , pp. 1389-1400
    • Chong, C.R.1    Janne, P.A.2
  • 228
    • 84859243184 scopus 로고    scopus 로고
    • The nuclear epidermal growth factor receptor signaling network and its role in cancer
    • [227] Brand, T.M., Iida, M., Li, C., Wheeler, D.L., The nuclear epidermal growth factor receptor signaling network and its role in cancer. Discov. Med. 12:66 (2011), 419–432.
    • (2011) Discov. Med. , vol.12 , Issue.66 , pp. 419-432
    • Brand, T.M.1    Iida, M.2    Li, C.3    Wheeler, D.L.4
  • 230
    • 84947788132 scopus 로고    scopus 로고
    • Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC
    • [229] Che, T.F., Lin, C.W., Wu, Y.Y., Chen, Y.J., Han, C.L., Chang, Y.L., Wu, C.T., Hsiao, T.H., Hong, T.M., Yang, P.C., Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC. Oncotarget 6:35 (2015), 37349–37366.
    • (2015) Oncotarget , vol.6 , Issue.35 , pp. 37349-37366
    • Che, T.F.1    Lin, C.W.2    Wu, Y.Y.3    Chen, Y.J.4    Han, C.L.5    Chang, Y.L.6    Wu, C.T.7    Hsiao, T.H.8    Hong, T.M.9    Yang, P.C.10
  • 231
    • 27144477683 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition
    • [230] Thomson, S., Buck, E., Petti, F., Griffin, G., Brown, E., Ramnarine, N., Iwata, K.K., Gibson, N., Haley, J.D., Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition. Cancer Res. 65:20 (2005), 9455–9462.
    • (2005) Cancer Res. , vol.65 , Issue.20 , pp. 9455-9462
    • Thomson, S.1    Buck, E.2    Petti, F.3    Griffin, G.4    Brown, E.5    Ramnarine, N.6    Iwata, K.K.7    Gibson, N.8    Haley, J.D.9
  • 233
    • 57049132745 scopus 로고    scopus 로고
    • Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy
    • [232] Thomson, S., Petti, F., Sujka-Kwok, I., Epstein, D., Haley, J.D., Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy. Clin. Exp. Metastasis 25:8 (2008), 843–854.
    • (2008) Clin. Exp. Metastasis , vol.25 , Issue.8 , pp. 843-854
    • Thomson, S.1    Petti, F.2    Sujka-Kwok, I.3    Epstein, D.4    Haley, J.D.5
  • 235
    • 35548962203 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer
    • [234] Mitsudomi, T., Yatabe, Y., Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer. Cancer Sci. 98:12 (2007), 1817–1824.
    • (2007) Cancer Sci. , vol.98 , Issue.12 , pp. 1817-1824
    • Mitsudomi, T.1    Yatabe, Y.2
  • 236
    • 84859822323 scopus 로고    scopus 로고
    • EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy
    • [235] Giannoni, E., Parri, M., Chiarugi, P., EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy. Antioxid. Redox Signal. 16:11 (2012), 1248–1263.
    • (2012) Antioxid. Redox Signal. , vol.16 , Issue.11 , pp. 1248-1263
    • Giannoni, E.1    Parri, M.2    Chiarugi, P.3
  • 238
    • 84871309537 scopus 로고    scopus 로고
    • Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation
    • [237] Truong, T.H., Carroll, K.S., Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation. Biochemistry 51:50 (2012), 9954–9965.
    • (2012) Biochemistry , vol.51 , Issue.50 , pp. 9954-9965
    • Truong, T.H.1    Carroll, K.S.2
  • 240
    • 84951072778 scopus 로고    scopus 로고
    • Redox-dependent regulation of epidermal growth factor receptor signaling
    • [239] Heppner, D.E., van der Vliet, A., Redox-dependent regulation of epidermal growth factor receptor signaling. Redox Biol. 8 (2016), 24–27.
    • (2016) Redox Biol. , vol.8 , pp. 24-27
    • Heppner, D.E.1    van der Vliet, A.2
  • 242
    • 84908347405 scopus 로고    scopus 로고
    • Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology
    • [241] Wani, R., Nagata, A., Murray, B.W., Protein redox chemistry: post-translational cysteine modifications that regulate signal transduction and drug pharmacology. Front. Pharmacol., 5(224), 2014.
    • (2014) Front. Pharmacol. , vol.5 , Issue.224
    • Wani, R.1    Nagata, A.2    Murray, B.W.3
  • 243
    • 85010934333 scopus 로고    scopus 로고
    • The role of sulfenic acids in cellular redox signaling: reconciling chemical kinetics and molecular detection strategies
    • [242] Heppner, D.E., Janssen-Heininger, Y.M., van der Vliet, A., The role of sulfenic acids in cellular redox signaling: reconciling chemical kinetics and molecular detection strategies. Arch. Biochem. Biophys. 616 (2017), 40–46.
    • (2017) Arch. Biochem. Biophys. , vol.616 , pp. 40-46
    • Heppner, D.E.1    Janssen-Heininger, Y.M.2    van der Vliet, A.3
  • 244
    • 84974816704 scopus 로고    scopus 로고
    • Epidermal growth factor-induced hydrogen peroxide production is mediated by dual oxidase 1
    • [243] Sirokmany, G., Pato, A., Zana, M., Donko, A., Biro, A., Nagy, P., Geiszt, M., Epidermal growth factor-induced hydrogen peroxide production is mediated by dual oxidase 1. Free Radic. Biol. Med. 97 (2016), 204–211.
    • (2016) Free Radic. Biol. Med. , vol.97 , pp. 204-211
    • Sirokmany, G.1    Pato, A.2    Zana, M.3    Donko, A.4    Biro, A.5    Nagy, P.6    Geiszt, M.7
  • 248
    • 84955605521 scopus 로고    scopus 로고
    • Stress-induced EGFR trafficking: mechanisms, functions, and therapeutic implications
    • [247] Tan, X., Lambert, P.F., Rapraeger, A.C., Anderson, R.A., Stress-induced EGFR trafficking: mechanisms, functions, and therapeutic implications. Trends Cell Biol. 26:5 (2016), 352–366.
    • (2016) Trends Cell Biol. , vol.26 , Issue.5 , pp. 352-366
    • Tan, X.1    Lambert, P.F.2    Rapraeger, A.C.3    Anderson, R.A.4
  • 249
    • 65349172964 scopus 로고    scopus 로고
    • Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation
    • [248] Morand, S., Ueyama, T., Tsujibe, S., Saito, N., Korzeniowska, A., Leto, T.L., Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation. FASEB J.: Off. Publ. Fed. Am. Soc. Exp. Biol. 23:4 (2009), 1205–1218.
    • (2009) FASEB J.: Off. Publ. Fed. Am. Soc. Exp. Biol. , vol.23 , Issue.4 , pp. 1205-1218
    • Morand, S.1    Ueyama, T.2    Tsujibe, S.3    Saito, N.4    Korzeniowska, A.5    Leto, T.L.6
  • 251
    • 84874841030 scopus 로고    scopus 로고
    • Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins
    • [250] Meitzler, J.L., Hinde, S., Banfi, B., Nauseef, W.M., Ortiz de Montellano, P.R., Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins. J. Biol. Chem. 288:10 (2013), 7147–7157.
    • (2013) J. Biol. Chem. , vol.288 , Issue.10 , pp. 7147-7157
    • Meitzler, J.L.1    Hinde, S.2    Banfi, B.3    Nauseef, W.M.4    Ortiz de Montellano, P.R.5
  • 252
    • 77953318772 scopus 로고    scopus 로고
    • NIP/DuoxA is essential for Drosophila embryonic development and regulates oxidative stress response
    • [251] Xie, X., Hu, J., Liu, X., Qin, H., Percival-Smith, A., Rao, Y., Li, S.S., NIP/DuoxA is essential for Drosophila embryonic development and regulates oxidative stress response. Int. J. Biol. Sci. 6:3 (2010), 252–267.
    • (2010) Int. J. Biol. Sci. , vol.6 , Issue.3 , pp. 252-267
    • Xie, X.1    Hu, J.2    Liu, X.3    Qin, H.4    Percival-Smith, A.5    Rao, Y.6    Li, S.S.7
  • 253
    • 1642483484 scopus 로고    scopus 로고
    • A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division
    • [252] Qin, H., Percival-Smith, A., Li, C., Jia, C.Y., Gloor, G., Li, S.S., A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division. J. Biol. Chem. 279:12 (2004), 11304–11312.
    • (2004) J. Biol. Chem. , vol.279 , Issue.12 , pp. 11304-11312
    • Qin, H.1    Percival-Smith, A.2    Li, C.3    Jia, C.Y.4    Gloor, G.5    Li, S.S.6
  • 254
    • 67650870232 scopus 로고    scopus 로고
    • Interplay between Numb and Notch in epithelial cancers: role for dual oxidase maturation factor
    • [253] Ostrakhovitch, E.A., Interplay between Numb and Notch in epithelial cancers: role for dual oxidase maturation factor. Eur. J. Cancer 45:12 (2009), 2071–2076.
    • (2009) Eur. J. Cancer , vol.45 , Issue.12 , pp. 2071-2076
    • Ostrakhovitch, E.A.1
  • 255
    • 85003422133 scopus 로고    scopus 로고
    • NOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?
    • [254] Huang, T., Zhou, Y., Cheng, A.S., Yu, J., To, K.F., Kang, W., NOTCH receptors in gastric and other gastrointestinal cancers: oncogenes or tumor suppressors?. Mol. Cancer, 15(1), 2016, 80.
    • (2016) Mol. Cancer , vol.15 , Issue.1 , pp. 80
    • Huang, T.1    Zhou, Y.2    Cheng, A.S.3    Yu, J.4    To, K.F.5    Kang, W.6
  • 256
    • 85011628751 scopus 로고    scopus 로고
    • Notch as a tumour suppressor
    • [255] Nowell, C.S., Radtke, F., Notch as a tumour suppressor. Nat. Rev. Cancer 17:3 (2017), 145–159.
    • (2017) Nat. Rev. Cancer , vol.17 , Issue.3 , pp. 145-159
    • Nowell, C.S.1    Radtke, F.2
  • 257
    • 85007569807 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and notch signaling in non-small-cell lung cancer
    • [256] Pancewicz-Wojtkiewicz, J., Epidermal growth factor receptor and notch signaling in non-small-cell lung cancer. Cancer Med. 5:12 (2016), 3572–3578.
    • (2016) Cancer Med. , vol.5 , Issue.12 , pp. 3572-3578
    • Pancewicz-Wojtkiewicz, J.1
  • 258
    • 84892415966 scopus 로고    scopus 로고
    • Dual oxidase maturation factor 1 (DUOXA1) overexpression increases reactive oxygen species production and inhibits murine muscle satellite cell differentiation
    • [257] Sandiford, S.D., Kennedy, K.A., Xie, X., Pickering, J.G., Li, S.S., Dual oxidase maturation factor 1 (DUOXA1) overexpression increases reactive oxygen species production and inhibits murine muscle satellite cell differentiation. Cell Commun. Signal.: CCS, 12, 2014, 5.
    • (2014) Cell Commun. Signal.: CCS , vol.12 , pp. 5
    • Sandiford, S.D.1    Kennedy, K.A.2    Xie, X.3    Pickering, J.G.4    Li, S.S.5
  • 259
    • 79953066375 scopus 로고    scopus 로고
    • p53-mediated regulation of neuronal differentiation via regulation of dual oxidase maturation factor 1
    • [258] Ostrakhovitch, E.A., Semenikhin, O.A., p53-mediated regulation of neuronal differentiation via regulation of dual oxidase maturation factor 1. Neurosci. Lett. 494:1 (2011), 80–85.
    • (2011) Neurosci. Lett. , vol.494 , Issue.1 , pp. 80-85
    • Ostrakhovitch, E.A.1    Semenikhin, O.A.2
  • 261
    • 74849106174 scopus 로고    scopus 로고
    • NIP1/DUOXA1 expression in epithelial breast cancer cells: regulation of cell adhesion and actin dynamics
    • [260] Ostrakhovitch, E.A., Li, S.S.C., NIP1/DUOXA1 expression in epithelial breast cancer cells: regulation of cell adhesion and actin dynamics. Breast Cancer Res. Treat. 119:3 (2010), 773–786.
    • (2010) Breast Cancer Res. Treat. , vol.119 , Issue.3 , pp. 773-786
    • Ostrakhovitch, E.A.1    Li, S.S.C.2
  • 262
    • 84869850999 scopus 로고    scopus 로고
    • DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies
    • [261] Fahy, J., Jeltsch, A., Arimondo, P.B., DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies. Expert Opin. Ther. Pat. 22:12 (2012), 1427–1442.
    • (2012) Expert Opin. Ther. Pat. , vol.22 , Issue.12 , pp. 1427-1442
    • Fahy, J.1    Jeltsch, A.2    Arimondo, P.B.3
  • 263
    • 24044451233 scopus 로고    scopus 로고
    • Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium
    • [262] Harper, R.W., Xu, C., Eiserich, J.P., Chen, Y., Kao, C.Y., Thai, P., Setiadi, H., Wu, R., Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium. FEBS Lett. 579:21 (2005), 4911–4917.
    • (2005) FEBS Lett. , vol.579 , Issue.21 , pp. 4911-4917
    • Harper, R.W.1    Xu, C.2    Eiserich, J.P.3    Chen, Y.4    Kao, C.Y.5    Thai, P.6    Setiadi, H.7    Wu, R.8
  • 264
    • 58149290251 scopus 로고    scopus 로고
    • The Pseudomonas toxin pyocyanin inhibits the dual oxidase-based antimicrobial system as it imposes oxidative stress on airway epithelial cells
    • (1950)
    • [263] Rada, B., Lekstrom, K., Damian, S., Dupuy, C., Leto, T.L., The Pseudomonas toxin pyocyanin inhibits the dual oxidase-based antimicrobial system as it imposes oxidative stress on airway epithelial cells. J. Immunol. 181:7 (2008), 4883–4893 (1950).
    • (2008) J. Immunol. , vol.181 , Issue.7 , pp. 4883-4893
    • Rada, B.1    Lekstrom, K.2    Damian, S.3    Dupuy, C.4    Leto, T.L.5
  • 267
    • 85020449188 scopus 로고    scopus 로고
    • Genetic and functional analysis of two missense DUOX2 mutations in congenital hypothyroidism and goiter
    • [266] Liu, S., Zhang, W., Zhang, L., Zou, H., Lu, K., Li, Q., Xia, H., Yan, S., Ma, X., Genetic and functional analysis of two missense DUOX2 mutations in congenital hypothyroidism and goiter. Oncotarget, 2016.
    • (2016) Oncotarget
    • Liu, S.1    Zhang, W.2    Zhang, L.3    Zou, H.4    Lu, K.5    Li, Q.6    Xia, H.7    Yan, S.8    Ma, X.9
  • 268
    • 84865399919 scopus 로고    scopus 로고
    • Metabolic syndrome is an independent risk factor for synchronous colorectal neoplasm in patients with gastric neoplasm
    • [267] Park, W., Lee, H., Kim, E.H., Yoon, J.Y., Park, J.C., Shin, S.K., Lee, S.K., Lee, Y.C., Kim, W.H., Noh, S.H., Metabolic syndrome is an independent risk factor for synchronous colorectal neoplasm in patients with gastric neoplasm. J. Gastroenterol. Hepatol. 27:9 (2012), 1490–1497.
    • (2012) J. Gastroenterol. Hepatol. , vol.27 , Issue.9 , pp. 1490-1497
    • Park, W.1    Lee, H.2    Kim, E.H.3    Yoon, J.Y.4    Park, J.C.5    Shin, S.K.6    Lee, S.K.7    Lee, Y.C.8    Kim, W.H.9    Noh, S.H.10
  • 269
    • 84926332170 scopus 로고    scopus 로고
    • Subclinical hypothyroidism as an independent risk factor for colorectal neoplasm
    • [268] Mu, G., Mu, X., Xing, H., Xu, R., Sun, G., Dong, C., Pan, Q., Xu, C., Subclinical hypothyroidism as an independent risk factor for colorectal neoplasm. Clin. Res. Hepatol. Gastroenterol. 39:2 (2015), 261–266.
    • (2015) Clin. Res. Hepatol. Gastroenterol. , vol.39 , Issue.2 , pp. 261-266
    • Mu, G.1    Mu, X.2    Xing, H.3    Xu, R.4    Sun, G.5    Dong, C.6    Pan, Q.7    Xu, C.8
  • 270
    • 84926657508 scopus 로고    scopus 로고
    • Subclinical hypothyroidism is associated with increased risk for cancer mortality in adult Taiwanese-a 10 years population-based cohort
    • [269] Tseng, F.Y., Lin, W.Y., Li, C.I., Li, T.C., Lin, C.C., Huang, K.C., Subclinical hypothyroidism is associated with increased risk for cancer mortality in adult Taiwanese-a 10 years population-based cohort. PLoS One, 10(4), 2015, e0122955.
    • (2015) PLoS One , vol.10 , Issue.4 , pp. e0122955
    • Tseng, F.Y.1    Lin, W.Y.2    Li, C.I.3    Li, T.C.4    Lin, C.C.5    Huang, K.C.6
  • 271
    • 33745174199 scopus 로고    scopus 로고
    • Genetic polymorphisms and susceptibility to lung disease
    • [270] Lee, P.L., West, C., Crain, K., Wang, L., Genetic polymorphisms and susceptibility to lung disease. J. Negat. Results Biomed., 5, 2006, 5.
    • (2006) J. Negat. Results Biomed. , vol.5 , pp. 5
    • Lee, P.L.1    West, C.2    Crain, K.3    Wang, L.4
  • 272
    • 84964896161 scopus 로고    scopus 로고
    • Dual oxidase 1: a predictive tool for the prognosis of hepatocellular carcinoma patients
    • [271] Chen, S., Ling, Q., Yu, K., Huang, C., Li, N., Zheng, J., Bao, S., Cheng, Q.I., Zhu, M., Chen, M., Dual oxidase 1: a predictive tool for the prognosis of hepatocellular carcinoma patients. Oncol. Rep. 35:6 (2016), 3198–3208.
    • (2016) Oncol. Rep. , vol.35 , Issue.6 , pp. 3198-3208
    • Chen, S.1    Ling, Q.2    Yu, K.3    Huang, C.4    Li, N.5    Zheng, J.6    Bao, S.7    Cheng, Q.I.8    Zhu, M.9    Chen, M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.