-
1
-
-
0035962632
-
DNA methylation, chromatin inheritance, and cancer
-
Rountree MR, Bachman KE, Hermann Baytin SB. DNA methylation, chromatin inheritance, and cancer. Oncogene 2001;20:3156-65.
-
(2001)
Oncogene
, vol.20
, pp. 3156-3165
-
-
Rountree, M.R.1
Bachman, K.E.2
Hermann Baytin, S.B.3
-
2
-
-
0021168535
-
DNA methylation patterns. Formation and function
-
Razin A, Szyf M. DNA methylation patterns. Formation and function. Biochim Biophys Acta 1984;782:331-42.
-
(1984)
Biochim Biophys Acta
, vol.782
, pp. 331-342
-
-
Razin, A.1
Szyf, M.2
-
3
-
-
0032168678
-
CpG methylation, chromatin structure and gene silencing - a three-way connection
-
Razin A. CpG methylation, chromatin structure and gene silencing - a three-way connection. EMBO J 1998; 17:4905-8.
-
(1998)
EMBO J
, vol.17
, pp. 4905-4908
-
-
Razin, A.1
-
4
-
-
0028223453
-
DNA methylation properties: Consequences for pharmacology
-
Szyf M. DNA methylation properties: consequences for pharmacology. Trends Pharmacol Sci l994;115:233-8
-
Trends Pharmacol Sci l994
, vol.115
, pp. 233-238
-
-
Szyf, M.1
-
5
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG. Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 2001;10:687-92.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
Schuebel, K.5
Herman, J.G.6
-
6
-
-
0027198976
-
increased cytosine DNA-methyltrasferase activity during colon cancer progression
-
Issa JP, Vertino PM, WU et al. increased cytosine DNA-methyltrasferase activity during colon cancer progression. J Natl Cancer Inst 1993;85:1235-40.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1235-1240
-
-
Issa, J.P.1
Vertino2
PM, W.U.3
-
7
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002;21:5400-13.
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
8
-
-
0036808531
-
Epigenomics: Genomewide study of methylation phenomena
-
Novik KL, Nimmrich I, Genc B, et al. Epigenomics: genomewide study of methylation phenomena. Curr Issues Mol Biol 2002;4:111-28.
-
(2002)
Curr Issues Mol Biol
, vol.4
, pp. 111-128
-
-
Novik, K.L.1
Nimmrich, I.2
Genc, B.3
-
9
-
-
0025880514
-
Growth regulation of mouse DNA methyltransferase gene expression
-
Szyf M, Bozovic V, Tanigawa G. Growth regulation of mouse DNA methyltransferase gene expression. J Biol Chem 1991;266:10027-30.
-
(1991)
J Biol Chem
, vol.266
, pp. 10027-10030
-
-
Szyf, M.1
Bozovic, V.2
Tanigawa, G.3
-
10
-
-
33845734101
-
AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 MRNA stability
-
Torrisani J, Unterberger A, Tendulkar SR, Shikimi K, Szyf M. AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 MRNA stability. Mol Cell Biol 2007;27:395-410.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 395-410
-
-
Torrisani, J.1
Unterberger, A.2
Tendulkar, S.R.3
Shikimi, K.4
Szyf, M.5
-
11
-
-
0029046134
-
Regulation of DNA methylation by the Ras signaling pathway
-
MacLeod AR, Rouleau J, Szyf M. Regulation of DNA methylation by the Ras signaling pathway. J Biol Chem 1995;270:11327-37.
-
(1995)
J Biol Chem
, vol.270
, pp. 11327-11337
-
-
MacLeod, A.R.1
Rouleau, J.2
Szyf, M.3
-
12
-
-
0035816688
-
A conserved 3′-untranslated element mediates growth regulation of DNA methyltransferase 1 and inhibits its transforming activity
-
Detich N, Ramchandani S, SzyfM. A conserved 3′-untranslated element mediates growth regulation of DNA methyltransferase 1 and inhibits its transforming activity. J Biol Chem 2001;276:24881-90.
-
(2001)
J Biol Chem
, vol.276
, pp. 24881-24890
-
-
Detich, N.1
Ramchandani, S.2
SzyfM3
-
13
-
-
0028964323
-
Expression of antisense to DNA methyltransferase MRNA induces DNA demethylation and inhibits tumorigenesis
-
MacLeod AR, Szyf M. Expression of antisense to DNA methyltransferase MRNA induces DNA demethylation and inhibits tumorigenesis. J Biol Chem 1995;270:8037-43.
-
(1995)
J Biol Chem
, vol.270
, pp. 8037-8043
-
-
MacLeod, A.R.1
Szyf, M.2
-
14
-
-
0031025621
-
Inhibition of tumorigenesis by a cytosine-DNA, methyttransferase, antisense oligodeoxynucleotide
-
Ramchandani S, MacLeod AR, Pinard M, von Hofe E, Szyf M. Inhibition of tumorigenesis by a cytosine-DNA, methyttransferase, antisense oligodeoxynucleotide. Proc Natl Acad Sci U S A 1997;94:684-9.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 684-689
-
-
Ramchandani, S.1
MacLeod, A.R.2
Pinard, M.3
von Hofe, E.4
Szyf, M.5
-
15
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird PW, Jackson-Grusby L, Fazeli A, et al. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 1995;81:197-205.
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Fazeli, A.3
-
16
-
-
0034054673
-
DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdil)
-
Milutinovic S, Knox JD, Szyf M. DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdil). J Biol Chem 2000;275:6353-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 6353-6359
-
-
Milutinovic, S.1
Knox, J.D.2
Szyf, M.3
-
17
-
-
33749594205
-
DNA methyltransferase 1 knockdown activates a replication stress checkpoint
-
Unterberger A, Andrews SD, Weaver IC, Szyf M. DNA methyltransferase 1 knockdown activates a replication stress checkpoint. Mol Cell Biol 2006;26:7575-86.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7575-7586
-
-
Unterberger, A.1
Andrews, S.D.2
Weaver, I.C.3
Szyf, M.4
-
18
-
-
0347622294
-
Targeting DNA methylation in cancer
-
Szyf M. Targeting DNA methylation in cancer. Ageing Res Rev 2003;2:299-328.
-
(2003)
Ageing Res Rev
, vol.2
, pp. 299-328
-
-
Szyf, M.1
-
19
-
-
0018860957
-
Cellular differentiation, cytidine analogs and DNA methylation
-
Jones PA, Taylor SM. Cellular differentiation, cytidine analogs and DNA methylation. Cell 1980;20:85-93.
-
(1980)
Cell
, vol.20
, pp. 85-93
-
-
Jones, P.A.1
Taylor, S.M.2
-
22
-
-
34948845116
-
Safety and clinical activity of the combination of 5-azacytidine, valproic acid and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome
-
Soriano AO, Yang H, Faderl S, et al. Safety and clinical activity of the combination of 5-azacytidine, valproic acid and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome. Blood 2007;110:2302-8.
-
(2007)
Blood
, vol.110
, pp. 2302-2308
-
-
Soriano, A.O.1
Yang, H.2
Faderl, S.3
-
23
-
-
0037420191
-
Inhibition of DNA methylation and reactivation of silenced genes by zebularine
-
Cheng JC, Matsen CB, Gonzales FA, et al. Inhibition of DNA methylation and reactivation of silenced genes by zebularine. J Natl Cancer Inst 2003;95:399-409.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 399-409
-
-
Cheng, J.C.1
Matsen, C.B.2
Gonzales, F.A.3
-
24
-
-
12444297637
-
Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks
-
Davis AJ, Gelmon KA, Siu LL, et al. Phase I and pharmacologic study of the human DNA methyltransferase antisense oligodeoxynucleotide MG98 given as a 21-day continuous infusion every 4 weeks. Invest New Drugs 2003;21:85-97.
-
(2003)
Invest New Drugs
, vol.21
, pp. 85-97
-
-
Davis, A.J.1
Gelmon, K.A.2
Siu, L.L.3
-
25
-
-
0034674440
-
Inhibition Of DNA methyltransferase inhibits DNA replication
-
Knox JD, Araujo FD, Bigey P, et al. Inhibition Of DNA methyltransferase inhibits DNA replication. J Biol Chem 2000;275:17986-90.
-
(2000)
J Biol Chem
, vol.275
, pp. 17986-17990
-
-
Knox, J.D.1
Araujo, F.D.2
Bigey, P.3
-
26
-
-
3042658499
-
DNA demethylation and cancer: Therapeutic implications
-
Szyf M, Pakneshan P, Rabbani SA. DNA demethylation and cancer: therapeutic implications. Cancer Lett 2004;211:133-43.
-
(2004)
Cancer Lett
, vol.211
, pp. 133-143
-
-
Szyf, M.1
Pakneshan, P.2
Rabbani, S.A.3
-
27
-
-
0041382127
-
Role of promoter methylation in regulation of the mammalian heparanase gene
-
Shteper PJ, Zcharia E, Ashhab Y, Peretz T, Vlodavsky I, BenYehuda D. Role of promoter methylation in regulation of the mammalian heparanase gene. Oncogene 2003;22:7737-49.
-
(2003)
Oncogene
, vol.22
, pp. 7737-7749
-
-
Shteper, P.J.1
Zcharia, E.2
Ashhab, Y.3
Peretz, T.4
Vlodavsky, I.5
BenYehuda, D.6
-
28
-
-
3843125363
-
Reversal of the hypomethylation status of urokinase (UPA) promoter blocks breast cancer growth and metastasis
-
Pakneshan P, Szyf M, Farias-Eisner F, Rabbani SA. Reversal of the hypomethylation status of urokinase (UPA) promoter blocks breast cancer growth and metastasis. J Biol Chem 2004;279:31735-44.
-
(2004)
J Biol Chem
, vol.279
, pp. 31735-31744
-
-
Pakneshan, P.1
Szyf, M.2
Farias-Eisner, F.3
Rabbani, S.A.4
-
29
-
-
0038080948
-
The methyl donor S-adenosylmethionine inhibits active demethylation of DNA: A candidate novel mechanism for the pharmacological effects of S-adenosylmethionine
-
Detich N, Hamm S, Just G, Knox JD, Szyf M. The methyl donor S-adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-adenosylmethionine. J Biol Chem 2003;278:20812-20.
-
(2003)
J Biol Chem
, vol.278
, pp. 20812-20820
-
-
Detich, N.1
Hamm, S.2
Just, G.3
Knox, J.D.4
Szyf, M.5
-
30
-
-
0025827620
-
Comparative effects of L-methionine, S-adenosyl-L-methionine and 5′-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis
-
Pascale RM, Simile MM, Satta G, et al. Comparative effects of L-methionine, S-adenosyl-L-methionine and 5′-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis. Anticancer Res 1991;11:1617-24.
-
(1991)
Anticancer Res
, vol.11
, pp. 1617-1624
-
-
Pascale, R.M.1
Simile, M.M.2
Satta, G.3
-
31
-
-
33749483782
-
Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo
-
Shukeir N, Pakneshan P, Chen G, Szyf M, Rabbani SA. Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo. Cancer Res 2006;66:9202-10.
-
(2006)
Cancer Res
, vol.66
, pp. 9202-9210
-
-
Shukeir, N.1
Pakneshan, P.2
Chen, G.3
Szyf, M.4
Rabbani, S.A.5
-
32
-
-
0033580326
-
A mammalian protein with specific demethylase activity for mCpG DNA [see comments]
-
Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M. A mammalian protein with specific demethylase activity for mCpG DNA [see comments]. Nature 1999;397:579-83.
-
(1999)
Nature
, vol.397
, pp. 579-583
-
-
Bhattacharya, S.K.1
Ramchandani, S.2
Cervoni, N.3
Szyf, M.4
|