-
1
-
-
67651065502
-
Genetic characterization of TET1 TET2, and TET3 alterations in myeloid malignancies
-
Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J , et al: Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood 114: 144-147 (2009).
-
(2009)
Blood
, vol.114
, pp. 144-147
-
-
Abdel-Wahab, O.1
Mullally, A.2
Hedvat, C.3
Garcia-Manero, G.4
Patel, J.5
-
2
-
-
84866445722
-
Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins
-
Arioka Y, Watanabe A, Saito K, Yamada Y: Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins. PloS One 7:e45031 (2012).
-
(2012)
PloS One
, vol.7
, pp. e45031
-
-
Arioka, Y.1
Watanabe, A.2
Saito, K.3
Yamada, Y.4
-
3
-
-
84885196364
-
Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma
-
Asmar F, Punj V, Christensen J, Pedersen MT, Pedersen A , et al: Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma. Haematologica 98: 1912-1920 (2013).
-
(2013)
Haematologica
, vol.98
, pp. 1912-1920
-
-
Asmar, F.1
Punj, V.2
Christensen, J.3
Pedersen, M.T.4
Pedersen, A.5
-
4
-
-
84881476916
-
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
-
Blaschke K, Ebata KT, Karimi MM, Zepeda-Martinez JA, Goyal P , et al: Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. Nature 500: 222-226 (2013).
-
(2013)
Nature
, vol.500
, pp. 222-226
-
-
Blaschke, K.1
Ebata, K.T.2
Karimi, M.M.3
Zepeda-Martinez, J.A.4
Goyal, P.5
-
5
-
-
84888133742
-
Epigenetic changes in the progression of Alzheimer's disease
-
Bradley-Whitman MA, Lovell MA: Epigenetic changes in the progression of Alzheimer's disease. Mech Ageing Dev 134: 486-495 (2013).
-
(2013)
Mech Ageing Dev
, vol.134
, pp. 486-495
-
-
Bradley-Whitman, M.A.1
Lovell, M.A.2
-
6
-
-
84862994335
-
Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus
-
Chen H, Dzitoyeva S, Manev H: Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus. Restor Neurol Neurosci 30: 237-245 (2012).
-
(2012)
Restor Neurol Neurosci
, vol.30
, pp. 237-245
-
-
Chen, H.1
Dzitoyeva, S.2
Manev, H.3
-
7
-
-
84872953223
-
TET2 promotes histone O-GlcNAcylation during gene transcription
-
Chen Q, Chen Y, Bian C, Fujiki R, Yu X: TET2 promotes histone O-GlcNAcylation during gene transcription. Nature 493: 561-564 (2013).
-
(2013)
Nature
, vol.493
, pp. 561-564
-
-
Chen, Q.1
Chen, Y.2
Bian, C.3
Fujiki, R.4
Yu, X.5
-
8
-
-
84868116669
-
Epigenetic regulation of stem cells differentiating along the neural lineage
-
Coskun V, Tsoa R, Sun YE: Epigenetic regulation of stem cells differentiating along the neural lineage. Curr Opin Neurobiol 22: 762-767 (2012).
-
(2012)
Curr Opin Neurobiol
, vol.22
, pp. 762-767
-
-
Coskun, V.1
Tsoa, R.2
Sun, Y.E.3
-
9
-
-
84875370281
-
NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
-
Costa Y, Ding J, Theunissen TW, Faiola F, Hore TA , et al: NANOG-dependent function of TET1 and TET2 in establishment of pluripotency. Nature 495: 370-374 (2013).
-
(2013)
Nature
, vol.495
, pp. 370-374
-
-
Costa, Y.1
Ding, J.2
Theunissen, T.W.3
Faiola, F.4
Hore, T.A.5
-
10
-
-
84898482006
-
Loss of Tet enzymes compromises proper differentiation of embryonic stem cells
-
Dawlaty MM, Breiling A, Le T, Barrasa MI, Raddatz G , et al: Loss of Tet enzymes compromises proper differentiation of embryonic stem cells. Dev Cell 29: 102-111 (2014).
-
(2014)
Dev Cell
, vol.29
, pp. 102-111
-
-
Dawlaty, M.M.1
Breiling, A.2
Le Barrasa T, M.I.3
Raddatz, G.4
-
11
-
-
66249137734
-
Mutation in TET2 in myeloid cancers
-
Delhommeau F, Dupont S, Della Valle V, James C, Trannoy S , et al: Mutation in TET2 in myeloid cancers. N Engl J Med 360: 2289-2301 (2009).
-
(2009)
N Engl J Med
, vol.360
, pp. 2289-2301
-
-
Delhommeau, F.1
Dupont, S.2
Della Valle, V.3
James, C.4
Trannoy, S.5
-
12
-
-
84875218124
-
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
-
Deplus R, Delatte B, Schwinn MK, Defrance M, Mendez J , et al: TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J 32: 645-655 (2013).
-
(2013)
EMBO J
, vol.32
, pp. 645-655
-
-
Deplus, R.1
Delatte, B.2
Schwinn, M.K.3
Defrance, M.4
Mendez, J.5
-
13
-
-
84884704614
-
Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate
-
Dickson KM, Gustafson CB, Young JI, Zuchner S, Wang G: Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate. Biochem Biophys Res Commun 439: 522-527 (2013).
-
(2013)
Biochem Biophys Res Commun
, vol.439
, pp. 522-527
-
-
Dickson, K.M.1
Gustafson, C.B.2
Young, J.I.3
Zuchner, S.4
Wang, G.5
-
14
-
-
84865486793
-
Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2
-
Doege CA, Inoue K, Yamashita T, Rhee DB, Travis S , et al: Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2. Nature 488: 652-655 (2012).
-
(2012)
Nature
, vol.488
, pp. 652-655
-
-
Doege, C.A.1
Inoue, K.2
Yamashita, T.3
Rhee, D.B.4
Travis, S.5
-
15
-
-
84992690903
-
Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation
-
Dong C, Zhang H, Xu C, Arrowsmith CH, Min J: Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation. IUCrJ 1: 540-549 (2014).
-
(2014)
IUCrJ
, vol.1
, pp. 540-549
-
-
Dong, C.1
Zhang, H.2
Xu, C.3
Arrowsmith, C.H.4
Min, J.5
-
16
-
-
84866104895
-
Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients
-
Dong E, Gavin DP, Chen Y, Davis J: Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients. Transl Psychiatry 2:e159 (2012).
-
(2012)
Transl Psychiatry
, vol.2
, pp. e159
-
-
Dong, E.1
Gavin, D.P.2
Chen, Y.3
Davis, J.4
-
17
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J , et al: Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18: 553-567 (2010).
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, J.5
-
18
-
-
84859512121
-
Beta-N-acetylglucosamine (OGlcNAc) is a novel regulator of mitosis-specific phosphorylations on histone H3
-
Fong JJ, Nguyen BL, Bridger R, Medrano EE, Wells L , et al: Beta-N-acetylglucosamine (OGlcNAc) is a novel regulator of mitosis-specific phosphorylations on histone H3. J Biol Chem 287: 12195-12203 (2012).
-
(2012)
J Biol Chem
, vol.287
, pp. 12195-12203
-
-
Fong, J.J.1
Nguyen, B.L.2
Bridger, R.3
Medrano, E.E.4
Wells, L.5
-
19
-
-
84887046365
-
Micro-RNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation
-
Fu X, Jin L, Wang X, Luo A, Hu J , et al: Micro-RNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation. Proc Natl Acad Sci USA 110: 17892-17897 (2013).
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 17892-17897
-
-
Fu, X.1
Jin, L.2
Wang, X.3
Luo, A.4
Hu, J.5
-
20
-
-
84355161950
-
GlcNAcylation of histone H2B facilitates its monoubiquitination
-
Fujiki R, Hashiba W, Sekine H, Yokoyama A, Chikanishi T , et al: GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature 480: 557-560 (2011).
-
(2011)
Nature
, vol.480
, pp. 557-560
-
-
Fujiki, R.1
Hashiba, W.2
Sekine, H.3
Yokoyama, A.4
Chikanishi, T.5
-
21
-
-
84883789401
-
Active DNA demethylation in post-mitotic neurons: A reason for optimism
-
Gavin DP, Chase KA, Sharma RP: Active DNA demethylation in post-mitotic neurons: A reason for optimism. Neuropharmacology 75: 233-245 (2013).
-
(2013)
Neuropharmacology
, vol.75
, pp. 233-245
-
-
Gavin, D.P.1
Chase, K.A.2
Sharma, R.P.3
-
22
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu TP, Guo F, Yang H, Wu HP, Xu GF , et al: The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477: 606-610 (2011).
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
Guo, F.2
Yang, H.3
Wu, H.P.4
Xu, G.F.5
-
23
-
-
84874252793
-
Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis
-
Hahn MA, Qiu R, Wu X, Li AX, Zhang H , et al: Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis. Cell Rep 3: 291-300 (2013).
-
(2013)
Cell Rep
, vol.3
, pp. 291-300
-
-
Hahn, M.A.1
Qiu, R.2
Wu, X.3
Li, A.X.4
Zhang, H.5
-
24
-
-
84894257068
-
Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA
-
Hashimoto H, Pais JE, Zhang X, Saleh L, Fu ZQ , et al: Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA. Nature 506: 391-395 (2014).
-
(2014)
Nature
, vol.506
, pp. 391-395
-
-
Hashimoto, H.1
Pais, J.E.2
Zhang, X.3
Saleh, L.4
Fu, Z.Q.5
-
25
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z, Liu P, Wang Y , et al: Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333: 1303-1307 (2011).
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
-
26
-
-
84894560490
-
Crystal structure of TET2-DNA complex: Insight into TET-mediated 5mC oxidation
-
Hu L, Li Z, Cheng J, Rao Q, Gong W , et al: Crystal structure of TET2-DNA complex: Insight into TET-mediated 5mC oxidation. Cell 155: 1545-1555 (2013).
-
(2013)
Cell
, vol.155
, pp. 1545-1555
-
-
Hu, L.1
Li, Z.2
Cheng, J.3
Rao, Q.4
Gong, W.5
-
27
-
-
84928184771
-
The methylcytosine dioxygenase TET2 promotes DNA demethylation and activation of cytokine gene expression in T cells
-
Ichiyama K, Chen T, Wang X, Yan X, Kim BS , et al: The methylcytosine dioxygenase TET2 promotes DNA demethylation and activation of cytokine gene expression in T cells. Immunity 42: 613-626 (2015).
-
(2015)
Immunity
, vol.42
, pp. 613-626
-
-
Ichiyama, K.1
Chen, T.2
Wang, X.3
Yan, X.4
Kim, B.S.5
-
28
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion ES-cell self-renewal and inner cell mass specification
-
Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC , et al: Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466: 1129-1133 (2010).
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
-
29
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito S, Shen L, Dai Q, Wu SC, Collins LB , et al: Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333: 1300-1303 (2011).
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
-
30
-
-
84883156126
-
Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function
-
Ivanov M, Kals M, Kacevska M, Barragan I, Kasuga K , et al: Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function. Genome Biol 14:R83 (2013).
-
(2013)
Genome Biol
, vol.14
, pp. R83
-
-
Ivanov, M.1
Kals, M.2
Kacevska, M.3
Barragan, I.4
Kasuga, K.5
-
31
-
-
67650588639
-
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
-
Jankowska AM, Szpurka H, Tiu RV, Makishima H, Afable M , et al: Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms. Blood 113: 6403-6410 (2009).
-
(2009)
Blood
, vol.113
, pp. 6403-6410
-
-
Jankowska, A.M.1
Szpurka, H.2
Tiu, R.V.3
Makishima, H.4
Afable, M.5
-
32
-
-
79960249232
-
Genomic mapping of 5-hydroxymethylcytosine in the human brain
-
Jin SG, Wu X, Li AX, Pfeifer GP: Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res 39: 5015-5024 (2011).
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 5015-5024
-
-
Jin, S.G.1
Wu, X.2
Li, A.X.3
Pfeifer, G.P.4
-
33
-
-
84868008258
-
The role of DNA methylation in aging, rejuvenation, and age-related disease
-
Johnson AA, Akman K, Calimport SR, Wuttke D, Stolzing A, et al: The role of DNA methylation in aging, rejuvenation, and age-related disease. Rejuvenation Res 15: 483-494 (2012).
-
(2012)
Rejuvenation Res
, vol.15
, pp. 483-494
-
-
Johnson, A.A.1
Akman, K.2
Calimport, S.R.3
Wuttke, D.4
Stolzing, A.5
-
34
-
-
84899024198
-
Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers
-
Kizuka Y, Kitazume S, Okahara K, Villagra A, Sotomayor EM , et al: Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers. J Biol Chem 289: 11253-11261 (2014).
-
(2014)
J Biol Chem
, vol.289
, pp. 11253-11261
-
-
Kizuka, Y.1
Kitazume, S.2
Okahara, K.3
Villagra, A.4
Sotomayor, E.M.5
-
35
-
-
84877582944
-
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX
-
Ko M, An J, Bandukwala HS, Chavez L, Aijo T , et al: Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Nature 497: 122-126 (2013).
-
(2013)
Nature
, vol.497
, pp. 122-126
-
-
Ko, M.1
An, J.2
Bandukwala, H.S.3
Chavez, L.4
Aijo, T.5
-
36
-
-
84886860116
-
TET enzymes TDG and the dynamics of DNA demethylation
-
Kohli RM, Zhang Y: TET enzymes, TDG and the dynamics of DNA demethylation. Nature 502: 472-479 (2013).
-
(2013)
Nature
, vol.502
, pp. 472-479
-
-
Kohli, R.M.1
Zhang, Y.2
-
37
-
-
70350438115
-
TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)
-
Kosmider O, Gelsi-Boyer V, Cheok M, Grabar S, Della-Valle V , et al: TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs). Blood 114: 3285-3291 (2009).
-
(2009)
Blood
, vol.114
, pp. 3285-3291
-
-
Kosmider, O.1
Gelsi-Boyer, V.2
Cheok, M.3
Grabar, S.4
Della-Valle, V.5
-
38
-
-
84875878011
-
Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells
-
Kubiura M, Okano M, Kimura H, Kawamura F, Tada M: Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells. Chromosome Res 20: 837-848 (2012).
-
(2012)
Chromosome Res
, vol.20
, pp. 837-848
-
-
Kubiura, M.1
Okano, M.2
Kimura, H.3
Kawamura, F.4
Tada, M.5
-
39
-
-
84863393235
-
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation
-
Kudo Y, Tateishi K, Yamamoto K, Yamamoto S, Asaoka Y , et al: Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation. Cancer Sci 103: 670-676 (2012).
-
(2012)
Cancer Sci
, vol.103
, pp. 670-676
-
-
Kudo, Y.1
Tateishi, K.2
Yamamoto, K.3
Yamamoto, S.4
Asaoka, Y.5
-
40
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
Langemeijer SM, Kuiper RP, Berends M, Knops R, Aslanyan MG , et al: Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat Genet 41: 838-842 (2009).
-
(2009)
Nat Genet
, vol.41
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
Knops, R.4
Aslanyan, M.G.5
-
41
-
-
84865197558
-
Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters
-
Lemonnier F, Couronne L, Parrens M, Jais JP, Travert M , et al: Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters. Blood 120: 1466-1469 (2012).
-
(2012)
Blood
, vol.120
, pp. 1466-1469
-
-
Lemonnier, F.1
Couronne, L.2
Parrens, M.3
Jais, J.P.4
Travert, M.5
-
42
-
-
84939874278
-
Critical role of Tet3 in neural progenitor cell maintenance and terminal differentiation
-
Li T, Yang D, Li J, Tang Y, Yang J, et al: Critical role of Tet3 in neural progenitor cell maintenance and terminal differentiation. Mol Neurobiol 51: 142-154 (2015).
-
(2015)
Mol Neurobiol
, vol.51
, pp. 142-154
-
-
Li, T.1
Yang, D.2
Li, J.3
Tang, Y.4
Yang, J.5
-
43
-
-
84877782460
-
5-Methylcytosine and 5-hydroxymethylcytosine each provide epigenetic information to the mouse zygote
-
Li Y, O'Neill C: 5-Methylcytosine and 5-hydroxymethylcytosine each provide epigenetic information to the mouse zygote. PloS One 8:e63689 (2013).
-
(2013)
PloS One
, vol.8
, pp. e63689
-
-
Li, Y.1
O'Neill, C.2
-
44
-
-
80052285127
-
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
-
Li Z, Cai X, Cai CL, Wang J, Zhang W , et al: Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood 118: 4509-4518 (2011).
-
(2011)
Blood
, vol.118
, pp. 4509-4518
-
-
Li, Z.1
Cai, X.2
Cai, C.L.3
Wang, J.4
Zhang, W.5
-
45
-
-
84866419591
-
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
-
Lian CG, Xu Y, Ceol C, Wu F, Larson A , et al: Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell 150: 1135-1146 (2012).
-
(2012)
Cell
, vol.150
, pp. 1135-1146
-
-
Lian, C.G.1
Xu, Y.2
Ceol, C.3
Wu, F.4
Larson, A.5
-
46
-
-
84877778628
-
Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules
-
Liu N, Wang M, Deng W, Schmidt CS, Qin W , et al: Intrinsic and extrinsic connections of Tet3 dioxygenase with CXXC zinc finger modules. PloS One 8:e62755 (2013).
-
(2013)
PloS One
, vol.8
, pp. e62755
-
-
Liu, N.1
Wang, M.2
Deng, W.3
Schmidt, C.S.4
Qin, W.5
-
47
-
-
84887096448
-
Teneleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity
-
Liu R, Jin Y, Tang WH, Qin L, Zhang X , et al: Teneleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity. Circulation 128: 2047-2057 (2013).
-
(2013)
Circulation
, vol.128
, pp. 2047-2057
-
-
Liu, R.1
Jin, Y.2
Tang, W.H.3
Qin, L.4
Zhang, X.5
-
48
-
-
84866018949
-
IDH1 mutations inhibit multiple alpha-ketoglutarate-dependent dioxygenase activities in astroglioma
-
Liu Y, Jiang W, Liu J, Zhao S, Xiong J , et al: IDH1 mutations inhibit multiple alpha-ketoglutarate-dependent dioxygenase activities in astroglioma. J Neurooncol 109: 253-260 (2012).
-
(2012)
J Neurooncol
, vol.109
, pp. 253-260
-
-
Liu, Y.1
Jiang, W.2
Liu, J.3
Zhao, S.4
Xiong, J.5
-
49
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E , et al: Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448: 553-560 (2007).
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
-
50
-
-
84877693964
-
Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine
-
Minor EA, Court BL, Young JI, Wang G: Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine. J Biol Chem 288: 13669-13674 (2013).
-
(2013)
J Biol Chem
, vol.288
, pp. 13669-13674
-
-
Minor, E.A.1
Court, B.L.2
Young, J.I.3
Wang, G.4
-
51
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D , et al: Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20: 11-24 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
-
52
-
-
84862551364
-
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos
-
Nakamura T, Liu YJ, Nakashima H, Umehara H, Inoue K , et al: PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature 486: 415-419 (2012).
-
(2012)
Nature
, vol.486
, pp. 415-419
-
-
Nakamura, T.1
Liu, Y.J.2
Nakashima, H.3
Umehara, H.4
Inoue, K.5
-
53
-
-
84883064448
-
Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells
-
Neri F, Incarnato D, Krepelova A, Rapelli S, Pagnani A , et al: Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells. Genome Biol 14:R91 (2013).
-
(2013)
Genome Biol
, vol.14
, pp. R91
-
-
Neri, F.1
Incarnato, D.2
Krepelova, A.3
Rapelli, S.4
Pagnani, A.5
-
54
-
-
84923377643
-
Single-base resolution analysis of 5-formyl and 5-carboxyl cytosine reveals promoter DNA methylation dynamics
-
Neri F, Incarnato D, Krepelova A, Rapelli S, Anselmi F , et al: Single-base resolution analysis of 5-formyl and 5-carboxyl cytosine reveals promoter DNA methylation dynamics. Cell Rep doi:10.1016/j.celrep.2015.01.008 (2015).
-
(2015)
Cell Rep
-
-
Neri, F.1
Incarnato, D.2
Krepelova, A.3
Rapelli, S.4
Anselmi, F.5
-
55
-
-
84891523954
-
PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells
-
Okashita N, Kumaki Y, Ebi K, Nishi M, Okamoto Y , et al: PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells. Development 141: 269-280 (2014).
-
(2014)
Development
, vol.141
, pp. 269-280
-
-
Okashita, N.1
Kumaki, Y.2
Ebi, K.3
Nishi, M.4
Okamoto, Y.5
-
56
-
-
84864053192
-
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma
-
Orr BA, Haffner MC, Nelson WG, Yegnasubramanian SE, Eberhart CG: Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. PloS One 7:e41036 (2012).
-
(2012)
PloS One
, vol.7
, pp. e41036
-
-
Orr, B.A.1
Haffner, M.C.2
Nelson, W.G.3
Yegnasubramanian, S.E.4
Eberhart, C.G.5
-
57
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R , et al: Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473: 394-397 (2011).
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
Lister, R.5
-
58
-
-
84887063691
-
UnTEThering (smooth muscle) cell plasticity
-
Prosdocimo DA, Jain R, Jain MK: UnTEThering (smooth muscle) cell plasticity. Circulation 128: 2002-2004 (2013).
-
(2013)
Circulation
, vol.128
, pp. 2002-2004
-
-
Prosdocimo, D.A.1
Jain, R.2
Jain, M.K.3
-
59
-
-
84899578932
-
Reduction in DNA methyltransferases and alteration of DNA methylation pattern associate with mouse skin ageing
-
Qian H, Xu X: Reduction in DNA methyltransferases and alteration of DNA methylation pattern associate with mouse skin ageing. Exp Dermatol 23: 357-359 (2014).
-
(2014)
Exp Dermatol
, vol.23
, pp. 357-359
-
-
Qian, H.1
Xu, X.2
-
60
-
-
80051596015
-
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron C, Couronne L, Della Valle V, Lopez CK, Plo I , et al: TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20: 25-38 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
Lopez, C.K.4
Plo, I.5
-
61
-
-
84865061978
-
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase
-
Raiber EA, Beraldi D, Ficz G, Burgess HE, Branco MR , et al: Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biol 13:R69 (2012).
-
(2012)
Genome Biol
, vol.13
, pp. R69
-
-
Raiber, E.A.1
Beraldi, D.2
Ficz, G.3
Burgess, H.E.4
Branco, M.R.5
-
62
-
-
79956220088
-
Inhibition of 2-oxoglutarate dependent oxygenases
-
Rose NR, McDonough MA, King ON, Kawamura A, Schofield CJ: Inhibition of 2-oxoglutarate dependent oxygenases. Chem Soc rev 40: 4364-4397 (2011).
-
(2011)
Chem Soc Rev
, vol.40
, pp. 4364-4397
-
-
Rose, N.R.1
McDonough, M.A.2
King, O.N.3
Kawamura, A.4
Schofield, C.J.5
-
63
-
-
84884241288
-
Tet1 is critical for neuronal activity-regulated gene expression and memory extinction
-
Rudenko A, Dawlaty MM, Seo J, Cheng AW, Meng J , et al: Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron 79: 1109-1122 (2013).
-
(2013)
Neuron
, vol.79
, pp. 1109-1122
-
-
Rudenko, A.1
Dawlaty, M.M.2
Seo, J.3
Cheng, A.W.4
Meng, J.5
-
64
-
-
84876946045
-
Genome-wide analysis reveals TETand TDG-dependent 5-methylcytosine oxidation dynamics
-
Shen L, Wu H, Diep D, Yamaguchi S, D'Alessio AC , et al: Genome-wide analysis reveals TETand TDG-dependent 5-methylcytosine oxidation dynamics. Cell 153: 692-706 (2013).
-
(2013)
Cell
, vol.153
, pp. 692-706
-
-
Shen, L.1
Wu, H.2
Diep, D.3
Yamaguchi, S.4
D'Alessio, A.C.5
-
65
-
-
84908402760
-
L-2-Hydroxyglutarate: An epigenetic modifier and putative oncometabolite in renal cancer
-
Shim EH, Livi CB, Rakheja D, Tan J, Benson D , et al: L-2-Hydroxyglutarate: An epigenetic modifier and putative oncometabolite in renal cancer. Cancer Discov 4: 1290-1298 (2014).
-
(2014)
Cancer Discov
, vol.4
, pp. 1290-1298
-
-
Shim, E.H.1
Livi, C.B.2
Rakheja, D.3
Tan, J.4
Benson, D.5
-
66
-
-
84876907152
-
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming
-
Song CX, Szulwach KE, Dai Q, Fu Y, Mao SQ , et al: Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell 153: 678-691 (2013).
-
(2013)
Cell
, vol.153
, pp. 678-691
-
-
Song, C.X.1
Szulwach, K.E.2
Dai, Q.3
Fu, Y.4
Mao, S.Q.5
-
67
-
-
84880571480
-
The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation
-
Song SJ, Ito K, Ala U, Kats L, Webster K , et al: The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation. Cell Stem Cell 13: 87-101 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 87-101
-
-
Song, S.J.1
Ito, K.2
Ala, U.3
Kats, L.4
Webster, K.5
-
68
-
-
79959209733
-
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
-
Stroud H, Feng S, Morey Kinney S, Pradhan S, Jacobsen SE: 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome Biology 12:R54 (2011).
-
(2011)
Genome Biology
, vol.12
, pp. R54
-
-
Stroud, H.1
Feng, S.2
Morey Kinney, S.3
Pradhan, S.4
Jacobsen, S.E.5
-
69
-
-
84870185931
-
Crosstalk between DNA and histones: Tet's new role in embryonic stem cells
-
Sui X, Price C, Li Z, Chen J: Crosstalk between DNA and histones: Tet's new role in embryonic stem cells. Curr Genomics 13: 603-608 (2012).
-
(2012)
Curr Genomics
, vol.13
, pp. 603-608
-
-
Sui, X.1
Price, C.2
Li, Z.3
Chen, J.4
-
70
-
-
84923952609
-
A sensitive approach to map genome-wide 5-hydroxymethylcytosine and 5-formylcytosine at single-base resolution
-
Sun Z, Dai N, Borgaro JG, Quimby A, Sun D , et al: A sensitive approach to map genome-wide 5-hydroxymethylcytosine and 5-formylcytosine at single-base resolution. Mol Cell 57: 750-761 (2015).
-
(2015)
Mol Cell
, vol.57
, pp. 750-761
-
-
Sun, Z.1
Dai, N.2
Borgaro, J.G.3
Quimby, A.4
Sun, D.5
-
71
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H , et al: Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324: 930-935 (2009).
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
-
72
-
-
33847055935
-
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
-
Valinluck V, Sowers LC: Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res 67: 946-950 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 946-950
-
-
Valinluck, V.1
Sowers, L.C.2
-
73
-
-
84874266225
-
Tet proteins connect the Olinked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells
-
Vella P, Scelfo A, Jammula S, Chiacchiera F, Williams K , et al: Tet proteins connect the Olinked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells. Mol Cell 49: 645-656 (2013).
-
(2013)
Mol Cell
, vol.49
, pp. 645-656
-
-
Vella, P.1
Scelfo, A.2
Jammula, S.3
Chiacchiera, F.4
Williams, K.5
-
74
-
-
84878591266
-
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency
-
Wang T, Wu H, Li Y, Szulwach KE, Lin L , et al: Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol 15: 700-711 (2013).
-
(2013)
Nat Cell Biol
, vol.15
, pp. 700-711
-
-
Wang, T.1
Wu, H.2
Li, Y.3
Szulwach, K.E.4
Lin, L.5
-
75
-
-
84555189745
-
DNA methylation: TET proteins-guardians of CpG islands
-
Williams K, Christensen J, Helin K: DNA methylation: TET proteins-guardians of CpG islands EMBO Rep 13: 28-35 (2012).
-
(2012)
EMBO Rep
, vol.13
, pp. 28-35
-
-
Williams, K.1
Christensen, J.2
Helin, K.3
-
76
-
-
79952713567
-
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
-
Wossidlo M, Nakamura T, Lepikhov K, Marques CJ, Zakhartchenko V , et al: 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat Commun 2: 241 (2011).
-
(2011)
Nat Commun
, vol.2
, pp. 241
-
-
Wossidlo, M.1
Nakamura, T.2
Lepikhov, K.3
Marques, C.J.4
Zakhartchenko, V.5
-
77
-
-
79961125686
-
Tet1 and 5-hydroxymethylation: A genome-wide view in mouse embryonic stem cells
-
Wu H, Zhang Y: Tet1 and 5-hydroxymethylation: A genome-wide view in mouse embryonic stem cells. Cell Cycle 10: 2428-2436 (2011).
-
(2011)
Cell Cycle
, vol.10
, pp. 2428-2436
-
-
Wu, H.1
Zhang, Y.2
-
78
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
Wu H, D'Alessio AC, Ito S, Wang Z, Cui K , et al: Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev 25: 679-684 (2011).
-
(2011)
Genes Dev
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Wang, Z.4
Cui, K.5
-
79
-
-
84878388525
-
Oct4 and the small molecule inhibitor, SC1, regulates Tet2 expression in mouse embryonic stem cells
-
Wu Y, Guo Z, Liu Y, Tang B, Wang Y , et al: Oct4 and the small molecule inhibitor, SC1, regulates Tet2 expression in mouse embryonic stem cells. Mol Biol Rep 40: 2897-2906 (2013).
-
(2013)
Mol Biol Rep
, vol.40
, pp. 2897-2906
-
-
Wu, Y.1
Guo, Z.2
Liu, Y.3
Tang, B.4
Wang, Y.5
-
80
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
Xu Y, Wu F, Tan L, Kong L, Xiong L , et al: Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell 42: 451-464 (2011).
-
(2011)
Mol Cell
, vol.42
, pp. 451-464
-
-
Xu, Y.1
Wu, F.2
Tan, L.3
Kong, L.4
Xiong, L.5
-
81
-
-
84874655393
-
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming
-
Yamaguchi S, Hong K, Liu R, Inoue A, Shen L , et al: Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming. Cell Res 23: 329-339 (2013a).
-
(2013)
Cell Res
, vol.23
, pp. 329-339
-
-
Yamaguchi, S.1
Hong, K.2
Liu, R.3
Inoue, A.4
Shen, L.5
-
82
-
-
84890568163
-
Role of Tet1 in erasure of genomic imprinting
-
Yamaguchi S, Shen L, Liu Y, Sendler D, Zhang Y: Role of Tet1 in erasure of genomic imprinting. Nature 504: 460-464 (2013b).
-
(2013)
Nature
, vol.504
, pp. 460-464
-
-
Yamaguchi, S.1
Shen, L.2
Liu, Y.3
Sendler, D.4
Zhang, Y.5
-
83
-
-
84873411803
-
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
-
Yang H, Liu Y, Bai F, Zhang JY, Ma SH , et al: Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene 32: 663-669 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 663-669
-
-
Yang, H.1
Liu, Y.2
Bai, F.3
Zhang, J.Y.4
Ma, S.H.5
-
84
-
-
84883443686
-
Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients
-
Yang Q, Wu K, Ji M, Jin W, He N , et al: Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients. J Biomed Nanotechnol 9: 1607-1616 (2013).
-
(2013)
J Biomed Nanotechnol
, vol.9
, pp. 1607-1616
-
-
Yang, Q.1
Wu, K.2
Ji, M.3
Jin, W.4
He, N.5
-
85
-
-
84880344660
-
Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals
-
Yin R, Mao SQ, Zhao B, Chong Z, Yang Y , et al: Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. J Am Chem Soc 135: 10396-10403 (2013).
-
(2013)
J Am Chem Soc
, vol.135
, pp. 10396-10403
-
-
Yin, R.1
Mao, S.Q.2
Zhao, B.3
Chong, Z.4
Yang, Y.5
-
86
-
-
84880947688
-
Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a
-
Zhang P, Huang B, Xu X, Sessa WC: Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a. Biochem Biophys Res Commun 437: 368-373 (2013).
-
(2013)
Biochem Biophys Res Commun
, vol.437
, pp. 368-373
-
-
Zhang, P.1
Huang, B.2
Xu, X.3
Sessa, W.C.4
-
87
-
-
80054818714
-
Modification of histones by sugar beta-Nacetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated
-
Zhang S, Roche K, Nasheuer HP, Lowndes NF: Modification of histones by sugar beta-Nacetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated. J Biol Chem 286: 37483-37495 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 37483-37495
-
-
Zhang, S.1
Roche, K.2
Nasheuer, H.P.3
Lowndes, N.F.4
|