-
2
-
-
16344364778
-
The scent of Nobel Prize success
-
The scent of Nobel Prize success Funct Neurol 19 2004 217 218
-
(2004)
Funct Neurol
, vol.19
, pp. 217-218
-
-
-
4
-
-
0022372783
-
Amplification and overexpression of the EGF receptor gene in primary human glioblastomas
-
T.A. Libermann, H.R. Nusbaum, N. Razon, R. Kris, I. Lax, and H. Soreq Amplification and overexpression of the EGF receptor gene in primary human glioblastomas J Cell Sci Suppl 3 1985 161 172
-
(1985)
J Cell Sci Suppl
, vol.3
, pp. 161-172
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
-
5
-
-
0021932240
-
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
-
T.A. Libermann, H.R. Nusbaum, N. Razon, R. Kris, I. Lax, and H. Soreq Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin Nature 313 1985 144 147
-
(1985)
Nature
, vol.313
, pp. 144-147
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
Kris, R.4
Lax, I.5
Soreq, H.6
-
6
-
-
0021363560
-
Expression of epidermal growth factor receptors in human brain tumors
-
T.A. Libermann, N. Razon, A.D. Bartal, Y. Yarden, J. Schlessinger, and H. Soreq Expression of epidermal growth factor receptors in human brain tumors Cancer Res 44 1984 753 760
-
(1984)
Cancer Res
, vol.44
, pp. 753-760
-
-
Libermann, T.A.1
Razon, N.2
Bartal, A.D.3
Yarden, Y.4
Schlessinger, J.5
Soreq, H.6
-
7
-
-
0023261096
-
Epidermal growth factor receptors in non-small cell lung cancer
-
D. Veale, T. Ashcroft, C. Marsh, G.J. Gibson, and A.L. Harris Epidermal growth factor receptors in non-small cell lung cancer Br J Cancer 55 1987 513 516
-
(1987)
Br J Cancer
, vol.55
, pp. 513-516
-
-
Veale, D.1
Ashcroft, T.2
Marsh, C.3
Gibson, G.J.4
Harris, A.L.5
-
8
-
-
0024315803
-
Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines
-
R.R. Weichselbaum, E.J. Dunphy, M.A. Beckett, A.G. Tybor, W.J. Moran, and M.E. Goldman Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines Head Neck 11 1989 437 442
-
(1989)
Head Neck
, vol.11
, pp. 437-442
-
-
Weichselbaum, R.R.1
Dunphy, E.J.2
Beckett, M.A.3
Tybor, A.G.4
Moran, W.J.5
Goldman, M.E.6
-
9
-
-
0020933452
-
Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors
-
J.D. Sato, T. Kawamoto, A.D. Le, J. Mendelsohn, J. Polikoff, and G.H. Sato Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors Mol Biol Med 1 1983 511 529
-
(1983)
Mol Biol Med
, vol.1
, pp. 511-529
-
-
Sato, J.D.1
Kawamoto, T.2
Le, A.D.3
Mendelsohn, J.4
Polikoff, J.5
Sato, G.H.6
-
10
-
-
0010233988
-
Growth stimulation of A431 cells by epidermal growth factor: Identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody
-
T. Kawamoto, J.D. Sato, A. Le, J. Polikoff, G.H. Sato, and J. Mendelsohn Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody Proc Natl Acad Sci USA 80 1983 1337 1341
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 1337-1341
-
-
Kawamoto, T.1
Sato, J.D.2
Le, A.3
Polikoff, J.4
Sato, G.H.5
Mendelsohn, J.6
-
11
-
-
0008486660
-
Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation
-
H. Sunada, B.E. Magun, J. Mendelsohn, and C.L. MacLeod Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation Proc Natl Acad Sci USA 83 1986 3825 3829
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 3825-3829
-
-
Sunada, H.1
Magun, B.E.2
Mendelsohn, J.3
Macleod, C.L.4
-
12
-
-
84859243184
-
The nuclear epidermal growth factor receptor signaling network and its role in cancer
-
T.M. Brand, M. Iida, C. Li, and D.L. Wheeler The nuclear epidermal growth factor receptor signaling network and its role in cancer Discov Med 12 2011 419 432
-
(2011)
Discov Med
, vol.12
, pp. 419-432
-
-
Brand, T.M.1
Iida, M.2
Li, C.3
Wheeler, D.L.4
-
13
-
-
77954759289
-
Nuclear trafficking of the epidermal growth factor receptor family membrane proteins
-
Y.N. Wang, H. Yamaguchi, J.M. Hsu, and M.C. Hung Nuclear trafficking of the epidermal growth factor receptor family membrane proteins Oncogene 29 2010 3997 4006
-
(2010)
Oncogene
, vol.29
, pp. 3997-4006
-
-
Wang, Y.N.1
Yamaguchi, H.2
Hsu, J.M.3
Hung, M.C.4
-
14
-
-
84858156041
-
Landscape of EGFR signaling network in human cancers: Biology and therapeutic response in relation to receptor subcellular locations
-
W. Han, and H.W. Lo Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations Cancer Lett 318 2012 124 134
-
(2012)
Cancer Lett
, vol.318
, pp. 124-134
-
-
Han, W.1
Lo, H.W.2
-
15
-
-
78649681031
-
The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus
-
Y.N. Wang, H. Yamaguchi, L. Huo, Y. Du, H.J. Lee, and H.H. Lee The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus J Biol Chem 285 2010 38720 38729
-
(2010)
J Biol Chem
, vol.285
, pp. 38720-38729
-
-
Wang, Y.N.1
Yamaguchi, H.2
Huo, L.3
Du, Y.4
Lee, H.J.5
Lee, H.H.6
-
16
-
-
77956265420
-
COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport
-
Y.N. Wang, H. Wang, H. Yamaguchi, H.J. Lee, H.H. Lee, and M.C. Hung COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport Biochem Biophys Res Commun 399 2010 498 504
-
(2010)
Biochem Biophys Res Commun
, vol.399
, pp. 498-504
-
-
Wang, Y.N.1
Wang, H.2
Yamaguchi, H.3
Lee, H.J.4
Lee, H.H.5
Hung, M.C.6
-
17
-
-
33746561717
-
Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1
-
H.W. Lo, M. Ali-Seyed, Y. Wu, G. Bartholomeusz, S.C. Hsu, and M.C. Hung Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1 J Cell Biochem 98 2006 1570 1583
-
(2006)
J Cell Biochem
, vol.98
, pp. 1570-1583
-
-
Lo, H.W.1
Ali-Seyed, M.2
Wu, Y.3
Bartholomeusz, G.4
Hsu, S.C.5
Hung, M.C.6
-
18
-
-
33947118714
-
Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression
-
H.J. Liao, and G. Carpenter Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression Mol Biol Cell 18 2007 1064 1072
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1064-1072
-
-
Liao, H.J.1
Carpenter, G.2
-
19
-
-
34249845380
-
Characterization of a novel tripartite nuclear localization sequence in the EGFR family
-
S.C. Hsu, and M.C. Hung Characterization of a novel tripartite nuclear localization sequence in the EGFR family J Biol Chem 282 2007 10432 10440
-
(2007)
J Biol Chem
, vol.282
, pp. 10432-10440
-
-
Hsu, S.C.1
Hung, M.C.2
-
20
-
-
84860872206
-
Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2
-
Y.N. Wang, H.H. Lee, H.J. Lee, Y. Du, H. Yamaguchi, and M.C. Hung Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2 J Biol Chem 287 2012 16869 16879
-
(2012)
J Biol Chem
, vol.287
, pp. 16869-16879
-
-
Wang, Y.N.1
Lee, H.H.2
Lee, H.J.3
Du, Y.4
Yamaguchi, H.5
Hung, M.C.6
-
21
-
-
0028032463
-
Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor
-
E.R. Eldredge, G.M. Korf, T.A. Christensen, D.C. Connolly, M.J. Getz, and N.J. Maihle Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor Mol Cell Biol 14 1994 7527 7534
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7527-7534
-
-
Eldredge, E.R.1
Korf, G.M.2
Christensen, T.A.3
Connolly, D.C.4
Getz, M.J.5
Maihle, N.J.6
-
22
-
-
0034855942
-
Nuclear localization of EGF receptor and its potential new role as a transcription factor
-
S.Y. Lin, K. Makino, W. Xia, A. Matin, Y. Wen, and K.Y. Kwong Nuclear localization of EGF receptor and its potential new role as a transcription factor Nat Cell Biol 3 2001 802 808
-
(2001)
Nat Cell Biol
, vol.3
, pp. 802-808
-
-
Lin, S.Y.1
Makino, K.2
Xia, W.3
Matin, A.4
Wen, Y.5
Kwong, K.Y.6
-
23
-
-
20444423286
-
Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway
-
H.W. Lo, S.C. Hsu, M. Ali-Seyed, M. Gunduz, W. Xia, and Y. Wei Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway Cancer Cell 7 2005 575 589
-
(2005)
Cancer Cell
, vol.7
, pp. 575-589
-
-
Lo, H.W.1
Hsu, S.C.2
Ali-Seyed, M.3
Gunduz, M.4
Xia, W.5
Wei, Y.6
-
24
-
-
31044450992
-
Co-regulation of B-Myb expression by E2F1 and EGF receptor
-
N. Hanada, H.W. Lo, C.P. Day, Y. Pan, Y. Nakajima, and M.C. Hung Co-regulation of B-Myb expression by E2F1 and EGF receptor Mol Carcinog 45 2006 10 17
-
(2006)
Mol Carcinog
, vol.45
, pp. 10-17
-
-
Hanada, N.1
Lo, H.W.2
Day, C.P.3
Pan, Y.4
Nakajima, Y.5
Hung, M.C.6
-
25
-
-
77249132723
-
Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes
-
H.W. Lo, X. Cao, H. Zhu, and F. Ali-Osman Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes Mol Cancer Res 8 2010 232 245
-
(2010)
Mol Cancer Res
, vol.8
, pp. 232-245
-
-
Lo, H.W.1
Cao, X.2
Zhu, H.3
Ali-Osman, F.4
-
26
-
-
48349140762
-
Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression
-
L.Y. Hung, J.T. Tseng, Y.C. Lee, W. Xia, Y.N. Wang, and M.L. Wu Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression Nucleic Acids Res 36 2008 4337 4351
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4337-4351
-
-
Hung, L.Y.1
Tseng, J.T.2
Lee, Y.C.3
Xia, W.4
Wang, Y.N.5
Wu, M.L.6
-
27
-
-
79955799333
-
A functional nuclear epidermal growth factor receptor, SRC and stat3 heteromeric complex in pancreatic cancer cells
-
S. Jaganathan, P. Yue, D.C. Paladino, J. Bogdanovic, Q. Huo, and J. Turkson A functional nuclear epidermal growth factor receptor, SRC and stat3 heteromeric complex in pancreatic cancer cells Plos One 6 2011 e19605
-
(2011)
Plos One
, vol.6
, pp. 19605
-
-
Jaganathan, S.1
Yue, P.2
Paladino, D.C.3
Bogdanovic, J.4
Huo, Q.5
Turkson, J.6
-
28
-
-
79957982003
-
Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells
-
W.C. Huang, Y.J. Chen, L.Y. Li, Y.L. Wei, S.C. Hsu, and S.L. Tsai Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells J Biol Chem 286 2011 20558 20568
-
(2011)
J Biol Chem
, vol.286
, pp. 20558-20568
-
-
Huang, W.C.1
Chen, Y.J.2
Li, L.Y.3
Wei, Y.L.4
Hsu, S.C.5
Tsai, S.L.6
-
29
-
-
28444453967
-
Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity
-
K. Dittmann, C. Mayer, and H.P. Rodemann Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity Radiother Oncol 76 2005 157 161
-
(2005)
Radiother Oncol
, vol.76
, pp. 157-161
-
-
Dittmann, K.1
Mayer, C.2
Rodemann, H.P.3
-
30
-
-
24744449739
-
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase
-
K. Dittmann, C. Mayer, B. Fehrenbacher, M. Schaller, U. Raju, and L. Milas Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase J Biol Chem 280 2005 31182 31189
-
(2005)
J Biol Chem
, vol.280
, pp. 31182-31189
-
-
Dittmann, K.1
Mayer, C.2
Fehrenbacher, B.3
Schaller, M.4
Raju, U.5
Milas, L.6
-
31
-
-
23844442173
-
Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis
-
A. Psyrri, Z. Yu, P.M. Weinberger, C. Sasaki, B. Haffty, and R. Camp Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis Clin Cancer Res 11 2005 5856 5862
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5856-5862
-
-
Psyrri, A.1
Yu, Z.2
Weinberger, P.M.3
Sasaki, C.4
Haffty, B.5
Camp, R.6
-
32
-
-
11244280137
-
Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer
-
H.W. Lo, W. Xia, Y. Wei, M. Ali-Seyed, S.F. Huang, and M.C. Hung Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer Cancer Res 65 2005 338 348
-
(2005)
Cancer Res
, vol.65
, pp. 338-348
-
-
Lo, H.W.1
Xia, W.2
Wei, Y.3
Ali-Seyed, M.4
Huang, S.F.5
Hung, M.C.6
-
33
-
-
67649225203
-
Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer
-
W. Xia, Y. Wei, Y. Du, J. Liu, B. Chang, and Y.L. Yu Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer Mol Carcinog 48 2009 610 617
-
(2009)
Mol Carcinog
, vol.48
, pp. 610-617
-
-
Xia, W.1
Wei, Y.2
Du, Y.3
Liu, J.4
Chang, B.5
Yu, Y.L.6
-
34
-
-
34248358971
-
Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma
-
M. Hoshino, H. Fukui, Y. Ono, A. Sekikawa, K. Ichikawa, and S. Tomita Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma Pathobiology 74 2007 15 21
-
(2007)
Pathobiology
, vol.74
, pp. 15-21
-
-
Hoshino, M.1
Fukui, H.2
Ono, Y.3
Sekikawa, A.4
Ichikawa, K.5
Tomita, S.6
-
35
-
-
84881328841
-
EGFR nuclear import in gallbladder carcinoma: Nuclear phosphorylated EGFR upregulates iNOS expression and confers independent prognostic impact
-
C.F. Li, F.M. Fang, J.M. Wang, C.C. Tzeng, H.C. Tai, and Y.C. Wei EGFR nuclear import in gallbladder carcinoma: nuclear phosphorylated EGFR upregulates iNOS expression and confers independent prognostic impact Ann Surg Oncol 2011
-
(2011)
Ann Surg Oncol
-
-
Li, C.F.1
Fang, F.M.2
Wang, J.M.3
Tzeng, C.C.4
Tai, H.C.5
Wei, Y.C.6
-
36
-
-
84887020378
-
Nuclear EGFR expression predicts poor survival in resected non-small cell lung cancer
-
A.M. Traynor, T.M. Weigel, K.R. Oettel, D.T. Yang, C. Zhang, and K. Kim Nuclear EGFR expression predicts poor survival in resected non-small cell lung cancer J Thorac Oncol 2012
-
(2012)
J Thorac Oncol
-
-
Traynor, A.M.1
Weigel, T.M.2
Oettel, K.R.3
Yang, D.T.4
Zhang, C.5
Kim, K.6
-
37
-
-
79551510855
-
EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment
-
G. Liccardi, J.A. Hartley, and D. Hochhauser EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment Cancer Res 71 2011 1103 1114
-
(2011)
Cancer Res
, vol.71
, pp. 1103-1114
-
-
Liccardi, G.1
Hartley, J.A.2
Hochhauser, D.3
-
38
-
-
70350653741
-
Nuclear EGFR contributes to acquired resistance to cetuximab
-
C. Li, M. Iida, E.F. Dunn, A.J. Ghia, and D.L. Wheeler Nuclear EGFR contributes to acquired resistance to cetuximab Oncogene 28 2009 3801 3813
-
(2009)
Oncogene
, vol.28
, pp. 3801-3813
-
-
Li, C.1
Iida, M.2
Dunn, E.F.3
Ghia, A.J.4
Wheeler, D.L.5
-
39
-
-
77953442037
-
Nuclear EGFR is required for cisplatin resistance and DNA repair
-
S.C. Hsu, S.A. Miller, Y. Wang, and M.C. Hung Nuclear EGFR is required for cisplatin resistance and DNA repair Am J Transl Res 1 2009 249 258
-
(2009)
Am J Transl Res
, vol.1
, pp. 249-258
-
-
Hsu, S.C.1
Miller, S.A.2
Wang, Y.3
Hung, M.C.4
-
40
-
-
84870218588
-
DNA repair dysregulation from cancer driver to therapeutic target
-
N.J. Curtin DNA repair dysregulation from cancer driver to therapeutic target Nat Rev Cancer 12 2012 801 817
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 801-817
-
-
Curtin, N.J.1
-
41
-
-
0030772168
-
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
-
R.K. SchmidtUllrich, R.B. Mikkelsen, P. Dent, D.G. Todd, K. Valerie, and B.D. Kavanagh Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation Oncogene 15 1997 1191 1197
-
(1997)
Oncogene
, vol.15
, pp. 1191-1197
-
-
Schmidtullrich, R.K.1
Mikkelsen, R.B.2
Dent, P.3
Todd, D.G.4
Valerie, K.5
Kavanagh, B.D.6
-
42
-
-
0033561522
-
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
-
S.M. Huang, J.M. Bock, and P.M. Harari Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck Cancer Res 59 1999 1935 1940
-
(1999)
Cancer Res
, vol.59
, pp. 1935-1940
-
-
Huang, S.M.1
Bock, J.M.2
Harari, P.M.3
-
43
-
-
0035238289
-
Monoclonal antibody blockade of the epidermal growth factor receptor in cancer therapy
-
S.M. Huang, J. Li, and P.M. Harari Monoclonal antibody blockade of the epidermal growth factor receptor in cancer therapy Cancer Chemother Biol Response Modif 19 2001 339 352
-
(2001)
Cancer Chemother Biol Response Modif
, vol.19
, pp. 339-352
-
-
Huang, S.M.1
Li, J.2
Harari, P.M.3
-
44
-
-
52749092194
-
Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK
-
K. Dittmann, C. Mayer, R. Kehlbach, and H.P. Rodemann Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK Mol Cancer 7 2008 69
-
(2008)
Mol Cancer
, vol.7
, pp. 69
-
-
Dittmann, K.1
Mayer, C.2
Kehlbach, R.3
Rodemann, H.P.4
-
45
-
-
77956939857
-
Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654
-
K. Dittmann, C. Mayer, B. Fehrenbacher, M. Schaller, R. Kehlbach, and H.P. Rodemann Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654 FEBS Lett 584 2010 3878 3884
-
(2010)
FEBS Lett
, vol.584
, pp. 3878-3884
-
-
Dittmann, K.1
Mayer, C.2
Fehrenbacher, B.3
Schaller, M.4
Kehlbach, R.5
Rodemann, H.P.6
-
46
-
-
34548499689
-
The radioprotector O-phospho-tyrosine stimulates DNA-repair via epidermal growth factor receptor- and DNA-dependent kinase phosphorylation
-
K. Dittmann, C. Mayer, G. Wanner, R. Kehlbach, and H.P. Rodemann The radioprotector O-phospho-tyrosine stimulates DNA-repair via epidermal growth factor receptor- and DNA-dependent kinase phosphorylation Radiother Oncol 84 2007 328 334
-
(2007)
Radiother Oncol
, vol.84
, pp. 328-334
-
-
Dittmann, K.1
Mayer, C.2
Wanner, G.3
Kehlbach, R.4
Rodemann, H.P.5
-
47
-
-
79960379461
-
Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access
-
K. Dittmann, C. Mayer, B. Fehrenbacher, M. Schaller, R. Kehlbach, and H.P. Rodemann Nuclear epidermal growth factor receptor modulates cellular radio-sensitivity by regulation of chromatin access Radiother Oncol 99 2011 317 322
-
(2011)
Radiother Oncol
, vol.99
, pp. 317-322
-
-
Dittmann, K.1
Mayer, C.2
Fehrenbacher, B.3
Schaller, M.4
Kehlbach, R.5
Rodemann, H.P.6
-
48
-
-
40249091300
-
The radioprotector Bowman-Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport
-
K. Dittmann, C. Mayer, R. Kehlbach, and H.P. Rodemann The radioprotector Bowman-Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport Radiother Oncol 86 2008 375 382
-
(2008)
Radiother Oncol
, vol.86
, pp. 375-382
-
-
Dittmann, K.1
Mayer, C.2
Kehlbach, R.3
Rodemann, H.P.4
-
49
-
-
40249109168
-
Activation of protein kinase C epsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation
-
G. Wanner, C. Mayer, R. Kehlbach, H.P. Rodemann, and K. Dittmann Activation of protein kinase C epsilon stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation Radiother Oncol 86 2008 383 390
-
(2008)
Radiother Oncol
, vol.86
, pp. 383-390
-
-
Wanner, G.1
Mayer, C.2
Kehlbach, R.3
Rodemann, H.P.4
Dittmann, K.5
-
50
-
-
84866128097
-
Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776
-
Y.L. Yu, R.H. Chou, C.H. Wu, Y.N. Wang, W.J. Chang, and Y.J. Tseng Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776 J Biol Chem 287 2012 31015 31026
-
(2012)
J Biol Chem
, vol.287
, pp. 31015-31026
-
-
Yu, Y.L.1
Chou, R.H.2
Wu, C.H.3
Wang, Y.N.4
Chang, W.J.5
Tseng, Y.J.6
-
51
-
-
18244379333
-
Cellular processing of platinum anticancer drugs
-
D. Wang, and S.J. Lippard Cellular processing of platinum anticancer drugs Nat Rev Drug Discov 4 2005 307 320
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 307-320
-
-
Wang, D.1
Lippard, S.J.2
-
52
-
-
46249087766
-
Mechanisms of acquired resistance to cetuximab: Role of HER (ErbB) family members
-
D.L. Wheeler, S. Huang, T.J. Kruser, M.M. Nechrebecki, E.A. Armstrong, and S. Benavente Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members Oncogene 27 2008 3944 3956
-
(2008)
Oncogene
, vol.27
, pp. 3944-3956
-
-
Wheeler, D.L.1
Huang, S.2
Kruser, T.J.3
Nechrebecki, M.M.4
Armstrong, E.A.5
Benavente, S.6
-
53
-
-
68049129871
-
Cetuximab/C225-induced intracellular trafficking of epidermal growth factor receptor
-
H.J. Liao, and G. Carpenter Cetuximab/C225-induced intracellular trafficking of epidermal growth factor receptor Cancer Res 69 2009 6179 6183
-
(2009)
Cancer Res
, vol.69
, pp. 6179-6183
-
-
Liao, H.J.1
Carpenter, G.2
-
54
-
-
78149357809
-
Dasatinib blocks cetuximab- and radiation-induced nuclear translocation of the epidermal growth factor receptor in head and neck squamous cell carcinoma
-
C. Li, M. Iida, E.F. Dunn, and D.L. Wheeler Dasatinib blocks cetuximab- and radiation-induced nuclear translocation of the epidermal growth factor receptor in head and neck squamous cell carcinoma Radiother Oncol 97 2010 330 337
-
(2010)
Radiother Oncol
, vol.97
, pp. 330-337
-
-
Li, C.1
Iida, M.2
Dunn, E.F.3
Wheeler, D.L.4
-
55
-
-
66149083997
-
Epidermal growth factor receptor cooperates with Src family kinases in acquired resistance to cetuximab
-
D.L. Wheeler, M. Iida, T.J. Kruser, M.M. Nechrebecki, E.F. Dunn, and E.A. Armstrong Epidermal growth factor receptor cooperates with Src family kinases in acquired resistance to cetuximab Cancer Biol Ther 8 2009 696 703
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 696-703
-
-
Wheeler, D.L.1
Iida, M.2
Kruser, T.J.3
Nechrebecki, M.M.4
Dunn, E.F.5
Armstrong, E.A.6
-
56
-
-
77956268839
-
Understanding resistance to EGFR inhibitors-impact on future treatment strategies
-
D.L. Wheeler, E.F. Dunn, and P.M. Harari Understanding resistance to EGFR inhibitors-impact on future treatment strategies Nat Rev Clin Oncol 7 2010 493 507
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 493-507
-
-
Wheeler, D.L.1
Dunn, E.F.2
Harari, P.M.3
-
57
-
-
79955513633
-
Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab
-
T.M. Brand, M. Iida, and D.L. Wheeler Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab Cancer Biol Ther 11 2011
-
(2011)
Cancer Biol Ther
, vol.11
-
-
Brand, T.M.1
Iida, M.2
Wheeler, D.L.3
-
58
-
-
67650128519
-
Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2
-
H.P. Kim, Y.K. Yoon, J.W. Kim, S.W. Han, H.S. Hur, and J. Park Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2 Plos One 4 2009
-
(2009)
Plos One
, vol.4
-
-
Kim, H.P.1
Yoon, Y.K.2
Kim, J.W.3
Han, S.W.4
Hur, H.S.5
Park, J.6
-
59
-
-
84875973325
-
Targeting the EGFR/PCNA signaling suppresses tumor growth of triple-negative breast cancer cells with cell-penetrating PCNA peptides
-
Y.L. Yu, R.H. Chou, J.H. Liang, W.J. Chang, K.J. Su, and Y.J. Tseng Targeting the EGFR/PCNA signaling suppresses tumor growth of triple-negative breast cancer cells with cell-penetrating PCNA peptides Plos One 8 2013
-
(2013)
Plos One
, vol.8
-
-
Yu, Y.L.1
Chou, R.H.2
Liang, J.H.3
Chang, W.J.4
Su, K.J.5
Tseng, Y.J.6
-
60
-
-
59049088211
-
Growth and molecular interactions of the anti-EGFR antibody cetuximab and the DNA cross-linking agent cisplatin in gefitinib-resistant MDA-MB-468 cells: New prospects in the treatment of triple-negative/basal-like breast cancer
-
C. Oliveras-Ferraros, A. Vazquez-Martin, E. Lopez-Bonet, B. Martin-Castillo, S. Del Barco, and J. Brunet Growth and molecular interactions of the anti-EGFR antibody cetuximab and the DNA cross-linking agent cisplatin in gefitinib-resistant MDA-MB-468 cells: new prospects in the treatment of triple-negative/basal-like breast cancer Int J Oncol 33 2008 1165 1176
-
(2008)
Int J Oncol
, vol.33
, pp. 1165-1176
-
-
Oliveras-Ferraros, C.1
Vazquez-Martin, A.2
Lopez-Bonet, E.3
Martin-Castillo, B.4
Del Barco, S.5
Brunet, J.6
-
61
-
-
42949176742
-
Survival of cancer cells is maintained by EGFR independent of its kinase activity
-
Z. Weihua, R. Tsan, W.C. Huang, Q. Wu, C.H. Chiu, and I.J. Fidler Survival of cancer cells is maintained by EGFR independent of its kinase activity Cancer Cell 13 2008 385 393
-
(2008)
Cancer Cell
, vol.13
, pp. 385-393
-
-
Weihua, Z.1
Tsan, R.2
Huang, W.C.3
Wu, Q.4
Chiu, C.H.5
Fidler, I.J.6
-
62
-
-
27344439995
-
Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation
-
Q. Wang, G. Villeneuve, and Z. Wang Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation EMBO Rep 6 2005 942 948
-
(2005)
EMBO Rep
, vol.6
, pp. 942-948
-
-
Wang, Q.1
Villeneuve, G.2
Wang, Z.3
-
63
-
-
84887015692
-
Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor
-
M. Iida, T.M. Brand, D.A. Campbell, C. Li, and D.L. Wheeler Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor Oncogene 2012
-
(2012)
Oncogene
-
-
Iida, M.1
Brand, T.M.2
Campbell, D.A.3
Li, C.4
Wheeler, D.L.5
-
64
-
-
0034793855
-
Cyclooxygenase-2 (COX-2) enzyme inhibitors as potential enhancers of tumor radioresponse
-
L. Milas Cyclooxygenase-2 (COX-2) enzyme inhibitors as potential enhancers of tumor radioresponse Semin Radiat Oncol 11 2001 290 299
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 290-299
-
-
Milas, L.1
-
65
-
-
0141540687
-
Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: A rational advance?
-
H. Choy, and L. Milas Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: a rational advance? J Natl Cancer Inst 95 2003 1440 1452
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1440-1452
-
-
Choy, H.1
Milas, L.2
-
66
-
-
1642407595
-
Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells
-
T.J. Maier, K. Schilling, R. Schmidt, G. Geisslinger, and S. Grosch Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells Biochem Pharmacol 67 2004 1469 1478
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1469-1478
-
-
Maier, T.J.1
Schilling, K.2
Schmidt, R.3
Geisslinger, G.4
Grosch, S.5
-
67
-
-
16344389993
-
Celecoxib inhibits prostate cancer growth: Evidence of a cyclooxygenase-2-independent mechanism
-
M.I. Patel, K. Subbaramaiah, B.H. Du, M. Chang, P.Y. Yang, and R.A. Newman Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism Clin Cancer Res 11 2005 1999 2007
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1999-2007
-
-
Patel, M.I.1
Subbaramaiah, K.2
Du, B.H.3
Chang, M.4
Yang, P.Y.5
Newman, R.A.6
-
68
-
-
37049038610
-
Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: A COX-2 independent mechanism
-
K.H. Dittmann, C. Mayer, P.A. Ohneseit, U. Raju, N.H. Andratschke, and L. Milas Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism Int J Radiat Oncol Biol Phys 70 2008 203 212
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.70
, pp. 203-212
-
-
Dittmann, K.H.1
Mayer, C.2
Ohneseit, P.A.3
Raju, U.4
Andratschke, N.H.5
Milas, L.6
-
69
-
-
33751508862
-
Tyrosine phosphorylation controls PCNA function through protein stability
-
S.C. Wang, Y. Nakajima, Y.L. Yu, W. Xia, C.T. Chen, and C.C. Yang Tyrosine phosphorylation controls PCNA function through protein stability Nat Cell Biol 8 2006 1359 1368
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1359-1368
-
-
Wang, S.C.1
Nakajima, Y.2
Yu, Y.L.3
Xia, W.4
Chen, C.T.5
Yang, C.C.6
-
70
-
-
77952394976
-
MUC1 regulates nuclear localization and function of the epidermal growth factor receptor
-
B.G. Bitler, A. Goverdhan, and J.A. Schroeder MUC1 regulates nuclear localization and function of the epidermal growth factor receptor J Cell Sci 123 2010 1716 1723
-
(2010)
J Cell Sci
, vol.123
, pp. 1716-1723
-
-
Bitler, B.G.1
Goverdhan, A.2
Schroeder, J.A.3
-
71
-
-
77958022249
-
RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus
-
L.F. Huo, Y.N. Wang, W.Y. Xia, S.C. Hsu, C.C. Lai, and L.Y. Li RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus Proc Natl Acad Sci USA 107 2010 16125 16130
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16125-16130
-
-
Huo, L.F.1
Wang, Y.N.2
Xia, W.Y.3
Hsu, S.C.4
Lai, C.C.5
Li, L.Y.6
-
72
-
-
84877575545
-
TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice
-
A. Li, C. Zhang, S. Gao, F. Chen, C. Yang, and R. Luo TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice Oncogene 32 2013 2273 2281
-
(2013)
Oncogene
, vol.32
, pp. 2273-2281
-
-
Li, A.1
Zhang, C.2
Gao, S.3
Chen, F.4
Yang, C.5
Luo, R.6
-
73
-
-
84865346500
-
Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1
-
Y. Shi, Y. Tao, Y. Jiang, Y. Xu, B. Yan, and X. Chen Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1 Carcinogenesis 33 2012 1468 1478
-
(2012)
Carcinogenesis
, vol.33
, pp. 1468-1478
-
-
Shi, Y.1
Tao, Y.2
Jiang, Y.3
Xu, Y.4
Yan, B.5
Chen, X.6
-
74
-
-
84887021610
-
Targeting the protein kinase C family: Are we there yet?
-
H.J. Mackay, and C.J. Twelves Targeting the protein kinase C family: are we there yet? Nat Rev Cancer 8 2008 255-255
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 255-255
-
-
Mackay, H.J.1
Twelves, C.J.2
-
75
-
-
77949400528
-
Genotyping of 73 Um-Scc head and neck squamous cell carcinoma cell lines
-
J.C. Brenner, M.P. Graham, B. Kumar, L.M. Saunders, R. Kupfer, and R.H. Lyons Genotyping of 73 Um-Scc head and neck squamous cell carcinoma cell lines Head Neck J Sci Spec 32 2010 417 426
-
(2010)
Head Neck J Sci Spec
, vol.32
, pp. 417-426
-
-
Brenner, J.C.1
Graham, M.P.2
Kumar, B.3
Saunders, L.M.4
Kupfer, R.5
Lyons, R.H.6
-
76
-
-
79958719008
-
Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib
-
M.E. Irwin, K.L. Mueller, N. Bohin, Y.B. Ge, and J.L. Boerner Lipid raft localization of EGFR alters the response of cancer cells to the EGFR tyrosine kinase inhibitor gefitinib J Cell Physiol 226 2011 2316 2328
-
(2011)
J Cell Physiol
, vol.226
, pp. 2316-2328
-
-
Irwin, M.E.1
Mueller, K.L.2
Bohin, N.3
Ge, Y.B.4
Boerner, J.L.5
|