메뉴 건너뛰기




Volumn 94, Issue 5, 2002, Pages 1593-1611

Monoclonal antibodies to target epidermal growth factor receptor-positive tumors a new paradigm for cancer therapy

Author keywords

(TGF ); ABX EGF; Carcinoma; Chemotherapy; EGF receptor (EGFR); EMD 55900; Epidermal growth factor (EGF); ICR 62; IMC C225; Monoclonal antibody; Radiation therapy; Transforming growth factor

Indexed keywords

AMPHIREGULIN; ANTIBODY; ANTIHISTAMINIC AGENT; BETACELLULIN; CANERTINIB; CISPLATIN; CYCLIN D1; CYCLIN DEPENDENT KINASE; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; ERLOTINIB; GEFITINIB; GEMCITABINE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; IRINOTECAN; MATRIX METALLOPROTEINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY EMD 55900; MONOCLONAL ANTIBODY ICR 62; MONOCLONAL ANTIBODY IMC C225; PANITUMUMAB; PROTEIN TYROSINE KINASE; RETINOBLASTOMA PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; TRASTUZUMAB; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 0036500831     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.10372     Document Type: Article
Times cited : (467)

References (149)
  • 14
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • (1999) J Clin Oncol , vol.17 , Issue.9 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 27
    • 0026028343 scopus 로고
    • Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers
    • (1991) Br Med Bull , vol.47 , Issue.1 , pp. 87-98
    • Gullick, W.J.1
  • 29
    • 0024276817 scopus 로고
    • The epidermal growth factor receptor as a multi-functional allosteric protein
    • (1988) Biochemistry , vol.27 , pp. 3119-3123
    • Schlessinger, J.1
  • 34
    • 0030054907 scopus 로고    scopus 로고
    • Anti-tumor and cell cycle responses in KB cells treated with a chimeric anti-EGFR monoclonal antibody in combination with cisplatin
    • (1996) Int J Oncol , vol.9 , pp. 217-224
    • Prewett, M.1    Rockwell, P.2    Rose, C.3
  • 36
    • 0033561522 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
    • (1999) Cancer Res , vol.59 , pp. 1935-1940
    • Huang, S.-M.1    Huang, S.-M.2    Harari, P.M.3
  • 43
    • 0031039923 scopus 로고    scopus 로고
    • Transforming growth factor-α-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation
    • (1997) EMBO J , vol.16 , pp. 750-759
    • Gille, J.1    Swerlick, P.A.2    Caughman, S.W.3
  • 45
  • 59
    • 0031907022 scopus 로고    scopus 로고
    • Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small cell lung cancer: Amphiregulin and microvessel count are independent prognostic indicators of survival
    • (1998) Clin Cancer Res , vol.4 , pp. 241-249
    • Fontanini, G.1    De Laurentiis, M.2    Vignati, S.3
  • 64
    • 0030936677 scopus 로고    scopus 로고
    • Studies of the expression of epidermal growth factor receptor in human renal cell carcinoma: A comparison of immunohistochemical method versus ligand binding assay
    • (1997) Oncology , vol.54 , pp. 220-225
    • Yoshida, K.1    Hosoya, Y.2    Sumi, S.3
  • 79
    • 2542507626 scopus 로고    scopus 로고
    • Impact of the expression of epidermal growth factor, transforming growth factor alpha, and epidermal growth factor receptor on the prognosis of superficial bladder cancer
    • (1998) Urology , vol.51 , pp. 645-649
    • Turkeri, L.N.1    Erton, M.L.2    Cevik, I.3    Akdas, A.4
  • 87
    • 0029398189 scopus 로고
    • Gene amplification in human gliomas
    • (1995) Glia , vol.15 , pp. 289-296
    • Collins, V.P.1
  • 98
    • 0032528051 scopus 로고    scopus 로고
    • Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1080-1087
    • He, Y.1    Zeng, Q.2    Drenning, S.D.3
  • 101
    • 0001223491 scopus 로고    scopus 로고
    • Neutralizing antibodies against epidermal growth factor and ErB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: Angiogenic implications for signal transduction therapy of solid tumors
    • (1997) Am J Pathol , vol.151 , pp. 1523-1530
    • Viloria Petit, A.M.1    Rak, J.2    Hung, M.-C.3
  • 104
    • 0032761526 scopus 로고    scopus 로고
    • Anti-angiogenic activity of selected receptor tyrosine kinase inhibitors, PD 166285 and PD173074: Implications for combination treatment with photodynamic therapy
    • (1999) Invest New Drugs , vol.17 , pp. 121-135
    • Dimitroff, C.J.1    Klohs, W.2    Sharma, A.3
  • 106
    • 0029049891 scopus 로고
    • Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor α in the progression of prostatic neoplasms
    • (1995) Clin Cancer Res , vol.1 , pp. 545-550
    • Scher, H.I.1    Sarkis, A.2    Reuter, V.3
  • 107
    • 0025775735 scopus 로고
    • Ligand-induced activation of A431 cell EGF receptors occurs primarily by an autocrine pathway that acts upon receptors on the surface rather than intracellularly
    • (1991) J Biol Chem , vol.266 , pp. 7503-7508
    • Van de Vijver, J.1    Kumar, R.2    Mendelsohn, J.3
  • 108
    • 0034104525 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors targeted to the epidermal growth factor receptor subfamily. Role as anticancer agents
    • (2000) Drugs , vol.59 , pp. 753-767
    • Noonberg, S.B.1    Benz, C.C.2
  • 112
    • 0001159137 scopus 로고    scopus 로고
    • A pilot trial demonstrates the safety of ZD-1839 ('Iressa'), an oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), in combination with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer
    • (2001) Proc Am Soc Clin Oncol , vol.19 , pp. 1301
    • Miller, V.A.1    Johnson, D.2    Heelan, R.T.3
  • 114
    • 0021254542 scopus 로고
    • Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity
    • (1984) J Biol Chem , vol.259 , pp. 7755-7760
    • Gill, G.N.1    Kawamoto, T.2    Cochet, C.3
  • 120
    • 18844473781 scopus 로고    scopus 로고
    • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms
    • (2000) Clin Cancer Res , vol.6 , Issue.5 , pp. 1936-1948
    • Bruns, C.J.1    Harbison, M.T.2    Davis, D.W.3
  • 126
    • 0031981553 scopus 로고    scopus 로고
    • A potent protein-tyrosine kinase inhibitor which selectively blocks proliferation of epidermal growth factor receptor-expressing tumor cells in vitro and in vivo
    • (1998) Int J Cancer , vol.76 , pp. 154-163
    • Lydon, N.B.1    Mett, H.2    Mueller, M.3
  • 132
    • 0001190385 scopus 로고    scopus 로고
    • Potentiation of radiation-induced breast cancer cell death by inhibition of epidermal growth factor family of receptors
    • (1999) Int J Radiat Biol , vol.45 , Issue.SUPPL. , pp. 162
    • Rao, G.S.1    Ethier, S.P.2
  • 133
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 134
    • 0034471959 scopus 로고    scopus 로고
    • Biological modifiers as potential radiosensitizers: Targeting the epidermal growth factor receptor family
    • (2000) Semin Oncol , vol.6 , pp. 15-20
    • Sartor, C.1
  • 137
    • 0032972944 scopus 로고    scopus 로고
    • Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice
    • (1999) Clin Cancer Res , vol.5 , Issue.2 , pp. 257-265
    • Perrotte, P.1    Matsumoto, T.2    Inoue, K.3
  • 140
    • 0000561747 scopus 로고    scopus 로고
    • Phase I trial of chimerized anti-epidermal growth factor receptor (EGFR) antibody in combination with either once-daily or twice-daily irradiation for locally advanced head and neck malignancies
    • (1999) Proc Am Soc Clin Oncol , vol.18 , pp. 1501
    • Ezekiel, M.P.1    Bonner, J.A.2    Robert, F.3
  • 143
    • 0030842059 scopus 로고    scopus 로고
    • Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in radiotherapy of advanced head and neck cancers: Results of the EORTC 22851 randomized trial
    • (1997) Radiother Oncol , vol.44 , pp. 111-121
    • Horiot, J.C.1    Bontemps, P.2    Van den Bogaert, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.