Up-regulation and sustained activation of Stat1 are essential for interferon-γ (IFN-γ)-induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines

Journal of Biological Chemistry

Volumn 286, Issue 14, 2011, Pages 12245-12256

  Wu, Yongzhong ^a   Antony, Smitha ^a   Juhasz, Agnes ^a   Lu, Jiamo ^a   Ge, Yun ^a   Jiang, Guojian ^a   Roy, Krishnendu ^a   Doroshow, James H ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINES; DUAL OXIDASE-2; EXTRACELLULAR; GENE FAMILIES; GROWTH FACTOR; HUMAN TUMOR CELLS; INFLAMMATORY RESPONSE; NADPH OXIDASE; OVER-EXPRESSION; PANCREATIC CANCERS; PATHOPHYSIOLOGIC; REACTIVE OXYGEN; REACTIVE OXYGEN SPECIES; SIGNALING EVENTS; SUSTAINED ACTIVATION; THYROID HORMONES; UP-REGULATION; UPPER AIRWAY; WOUND HEALING;

BIOCHEMISTRY; CELL CULTURE; DISEASES; ENZYME ACTIVITY; GENES; OXYGEN; TUMORS;

CELLS;

DUAL OXIDASE 2; DUAL OXIDASE A2; GAMMA INTERFERON; INTERFERON REGULATORY FACTOR; JANUS KINASE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER CELL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; HUMANS; HYDROGEN PEROXIDE; INTERFERON-GAMMA; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; NADPH OXIDASE; ONIUM COMPOUNDS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; STAT1 TRANSCRIPTION FACTOR;

EID: 79953303217     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.191031     Document Type: Article

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