-
1
-
-
0019406986
-
Iodination of thyroglobulin: An intracellular or extracellular process?
-
Ekholm, R. Iodination of thyroglobulin: an intracellular or extracellular process? Mol. Cell. Endocrinol. 24, 141-163 (1981).
-
(1981)
Mol. Cell. Endocrinol
, vol.24
, pp. 141-163
-
-
Ekholm, R.1
-
2
-
-
0033601327
-
Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cDNAs
-
Dupuy, C. et al. Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cDNAs. J. Biol. Chem. 274, 37265-37269 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 37265-37269
-
-
Dupuy, C.1
-
3
-
-
0034725643
-
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family
-
De Deken, X. et al. Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J. Biol. Chem. 275, 23227-23233 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 23227-23233
-
-
De Deken, X.1
-
4
-
-
77449129856
-
Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues
-
Weyemi, U. et al. Intracellular expression of reactive oxygen species-generating NADPH oxidase NOX4 in normal and cancer thyroid tissues. Endocr. Relat. Cancer 17, 27-37 (2010).
-
(2010)
Endocr. Relat. Cancer
, vol.17
, pp. 27-37
-
-
Weyemi, U.1
-
5
-
-
44949106317
-
Structure regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species
-
Sumimoto, H. Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species. FEBS J. 275, 3249-3277 (2008).
-
(2008)
FEBS J
, vol.275
, pp. 3249-3277
-
-
Sumimoto, H.1
-
6
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth, J. D. NOX enzymes and the biology of reactive oxygen. Nat. Rev. Immunol. 4, 181-189 (2004).
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
7
-
-
84901036297
-
Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling
-
De Deken, X., Corvilain, B., Dumont, J. E., Miot, F. Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling. Antioxid. Redox Signal. 20, 2776-2793 (2014).
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 2776-2793
-
-
De Deken, X.1
Corvilain, B.2
Dumont, J.E.3
Miot, F.4
-
8
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
Bedard, K., Krause, K. H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 87, 245-313 (2007).
-
(2007)
Physiol. Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
9
-
-
84921932554
-
DNA replication stress as a hallmark of cancer
-
Macheret, M., Halazonetis, T. D. DNA replication stress as a hallmark of cancer. Annu. Rev. Pathol. 10, 425-448 (2015).
-
(2015)
Annu. Rev. Pathol
, vol.10
, pp. 425-448
-
-
MacHeret, M.1
Halazonetis, T.D.2
-
10
-
-
33745144355
-
Deoxyribonucleic acid damage and spontaneous mutagenesis in the thyroid gland of rats and mice
-
Maier, J. et al. Deoxyribonucleic acid damage and spontaneous mutagenesis in the thyroid gland of rats and mice. Endocrinology 147, 3391-3397 (2006).
-
(2006)
Endocrinology
, vol.147
, pp. 3391-3397
-
-
Maier, J.1
-
11
-
-
34648824394
-
Mechanisms of disease: Hydrogen peroxide DNA damage and mutagenesis in the development of thyroid tumors
-
Krohn, K., Maier, J., Paschke, R. Mechanisms of disease: hydrogen peroxide, DNA damage and mutagenesis in the development of thyroid tumors. Nat. Clin. Pract. Endocrinol. Metab. 3, 713-720 (2007).
-
(2007)
Nat. Clin. Pract. Endocrinol. Metab
, vol.3
, pp. 713-720
-
-
Krohn, K.1
Maier, J.2
Paschke, R.3
-
12
-
-
84855947011
-
Evidence of oncogene-induced senescence in thyroid carcinogenesis
-
Vizioli, M. G. et al. Evidence of oncogene-induced senescence in thyroid carcinogenesis. Endocr. Relat. Cancer 18, 743-757 (2011).
-
(2011)
Endocr. Relat. Cancer
, vol.18
, pp. 743-757
-
-
Vizioli, M.G.1
-
13
-
-
38749090568
-
Foci formation of P53-binding protein 1 in thyroid tumors: Activation of genomic instability during thyroid carcinogenesis
-
Nakashima, M. et al. Foci formation of P53-binding protein 1 in thyroid tumors: activation of genomic instability during thyroid carcinogenesis. Int. J. Cancer 122, 1082-1088 (2008).
-
(2008)
Int. J. Cancer
, vol.122
, pp. 1082-1088
-
-
Nakashima, M.1
-
14
-
-
84885432843
-
Significance of p53-binding protein 1 (53BP1) expression in thyroid papillary microcarcinoma: Association with BRAFV600E mutation status
-
Mussazhanova, Z. et al. Significance of p53-binding protein 1 (53BP1) expression in thyroid papillary microcarcinoma: association with BRAFV600E mutation status. Histopathology 63, 726-734 (2013).
-
(2013)
Histopathology
, vol.63
, pp. 726-734
-
-
Mussazhanova, Z.1
-
15
-
-
84857790798
-
ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
-
Weyemi, U. et al. ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence. Oncogene 31, 1117-1129 (2012).
-
(2012)
Oncogene
, vol.31
, pp. 1117-1129
-
-
Weyemi, U.1
-
16
-
-
84928152214
-
NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation
-
Ameziane-El-Hassani, R. et al. NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation. Proc. Natl Acad. Sci. USA 112, 5051-5056 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 5051-5056
-
-
Ameziane-El-Hassani, R.1
-
17
-
-
77649250810
-
Nuclear redox signaling
-
Lukosz, M. et al. Nuclear redox signaling. Antioxid. Redox Signal. 12, 713-742 (2010).
-
(2010)
Antioxid. Redox Signal
, vol.12
, pp. 713-742
-
-
Lukosz, M.1
-
18
-
-
34147210988
-
Hydrogen peroxide sensing and signaling
-
Veal, E. A., Day, A. M., Morgan, B. A. Hydrogen peroxide sensing and signaling. Mol. Cell 26, 1-14 (2007).
-
(2007)
Mol. Cell
, vol.26
, pp. 1-14
-
-
Veal, E.A.1
Day, A.M.2
Morgan, B.A.3
-
19
-
-
77957652745
-
Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling
-
Miller, E. W., Dickinson, B. C., Chang, C. J. Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling. Proc. Natl Acad. Sci. USA 107, 15681-15686 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15681-15686
-
-
Miller, E.W.1
Dickinson, B.C.2
Chang, C.J.3
-
20
-
-
0029394936
-
Hydrogen peroxide and the proliferation of BHK-21 cells
-
Burdon, R. H., Alliangana, D., Gill, V. Hydrogen peroxide and the proliferation of BHK-21 cells. Free Radic. Res. 23, 471-486 (1995).
-
(1995)
Free Radic. Res
, vol.23
, pp. 471-486
-
-
Burdon, R.H.1
Alliangana, D.2
Gill, V.3
-
21
-
-
0036184190
-
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
-
Meng, T. C., Fukada, T., Tonks, N. K. Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol. Cell 9, 387-399 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 387-399
-
-
Meng, T.C.1
Fukada, T.2
Tonks, N.K.3
-
22
-
-
48249149472
-
A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells
-
Boivin, B., Zhang, S., Arbiser, J. L., Zhang, Z. Y., Tonks, N. K. A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells. Proc. Natl Acad. Sci. USA 105, 9959-9964 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 9959-9964
-
-
Boivin, B.1
Zhang, S.2
Arbiser, J.L.3
Zhang, Z.Y.4
Tonks, N.K.5
-
23
-
-
0026583944
-
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity
-
Xanthoudakis, S., Curran, T. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J. 11, 653-665 (1992).
-
(1992)
EMBO J
, vol.11
, pp. 653-665
-
-
Xanthoudakis, S.1
Curran, T.2
-
24
-
-
84947748326
-
Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins
-
Verrastro, I., Tveen-Jensen, K., Woscholski, R., Spickett, C. M., Pitt, A. R. Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins. Free Radic. Biol. Med. 90, 24-34 (2015).
-
(2015)
Free Radic. Biol. Med
, vol.90
, pp. 24-34
-
-
Verrastro, I.1
Tveen-Jensen, K.2
Woscholski, R.3
Spickett, C.M.4
Pitt, A.R.5
-
25
-
-
0027361046
-
Redox modulation of p53 conformation and sequence-specific DNA binding in vitro
-
Hainaut, P., Milner, J. Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res. 53, 4469-4473 (1993).
-
(1993)
Cancer Res
, vol.53
, pp. 4469-4473
-
-
Hainaut, P.1
Milner, J.2
-
26
-
-
0025077481
-
Redox regulation of fos and jun DNA-binding activity in vitro
-
Abate, C., Patel, L., Rauscher, F. J., 3rd & Curran, T. Redox regulation of fos and jun DNA-binding activity in vitro. Science 249, 1157-1161 (1990).
-
(1990)
Science
, vol.249
, pp. 1157-1161
-
-
Abate, C.1
Patel, L.2
Rauscher, F.J.3
Curran, T.4
-
27
-
-
0023175462
-
Absence of both cytochrome b-245 subunits from neutrophils in X-linked chronic granulomatous disease
-
Segal, A. W. Absence of both cytochrome b-245 subunits from neutrophils in X-linked chronic granulomatous disease. Nature 326, 88-91 (1987).
-
(1987)
Nature
, vol.326
, pp. 88-91
-
-
Segal, A.W.1
-
28
-
-
0024513954
-
Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease
-
Parkos, C. A., Dinauer, M. C., Jesaitis, A. J., Orkin, S. H., Curnutte, J. T. Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease. Blood 73, 1416-1420 (1989).
-
(1989)
Blood
, vol.73
, pp. 1416-1420
-
-
Parkos, C.A.1
Dinauer, M.C.2
Jesaitis, A.J.3
Orkin, S.H.4
Curnutte, J.T.5
-
29
-
-
70350380878
-
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
-
Lipinski, S. et al. DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses. J. Cell Sci. 122, 3522-3530 (2009).
-
(2009)
J. Cell Sci
, vol.122
, pp. 3522-3530
-
-
Lipinski, S.1
-
30
-
-
77950234253
-
A peroxidase/dual oxidase system modulates midgut epithelial immunity in Anopheles gambiae
-
Kumar, S., Molina-Cruz, A., Gupta, L., Rodrigues, J., Barillas-Mury, C. A peroxidase/dual oxidase system modulates midgut epithelial immunity in Anopheles gambiae. Science 327, 1644-1648 (2010).
-
(2010)
Science
, vol.327
, pp. 1644-1648
-
-
Kumar, S.1
Molina-Cruz, A.2
Gupta, L.3
Rodrigues, J.4
Barillas-Mury, C.5
-
31
-
-
33845430467
-
Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade
-
Koff, J. L., Shao, M. X., Kim, S., Ueki, I. F., Nadel, J. A. Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade. J. Immunol. 177, 8693-8700 (2006).
-
(2006)
J. Immunol
, vol.177
, pp. 8693-8700
-
-
Koff, J.L.1
Shao, M.X.2
Kim, S.3
Ueki, I.F.4
Nadel, J.A.5
-
32
-
-
0042203535
-
Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense
-
Geiszt, M., Witta, J., Baffi, J., Lekstrom, K., Leto, T. L. Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense. FASEB J. 17, 1502-1504 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 1502-1504
-
-
Geiszt, M.1
Witta, J.2
Baffi, J.3
Lekstrom, K.4
Leto, T.L.5
-
33
-
-
67650519057
-
ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli
-
Boots, A. W. et al. ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli. J. Biol. Chem. 284, 17858-17867 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, pp. 17858-17867
-
-
Boots, A.W.1
-
34
-
-
0026021362
-
Production of large amounts of hydrogen peroxide by human tumor cells
-
Szatrowski, T. P., Nathan, C. F. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 51, 794-798 (1991).
-
(1991)
Cancer Res
, vol.51
, pp. 794-798
-
-
Szatrowski, T.P.1
Nathan, C.F.2
-
35
-
-
59849084800
-
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation
-
Aykin-Burns, N., Ahmad, I. M., Zhu, Y., Oberley, L. W., Spitz, D. R. Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation. Biochem. J. 418, 29-37 (2009).
-
(2009)
Biochem. J
, vol.418
, pp. 29-37
-
-
Aykin-Burns, N.1
Ahmad, I.M.2
Zhu, Y.3
Oberley, L.W.4
Spitz, D.R.5
-
36
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova, J. et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434, 864-870 (2005).
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
-
37
-
-
0028208968
-
A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox
-
Leusen, J. H. et al. A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox. J. Clin. Invest. 93, 2120-2126 (1994).
-
(1994)
J. Clin. Invest
, vol.93
, pp. 2120-2126
-
-
Leusen, J.H.1
-
38
-
-
33745821178
-
Identification of the maturation factor for dual oxidase Evolution of an eukaryotic operon equivalent
-
Grasberger, H., Refetoff, S. Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent. J. Biol. Chem. 281, 18269-18272 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 18269-18272
-
-
Grasberger, H.1
Refetoff, S.2
-
39
-
-
1142309762
-
Structural and functional characterization of the two human ThOX/Duox genes and their 5?-flanking regions
-
Pachucki, J., Wang, D., Christophe, D., Miot, F. Structural and functional characterization of the two human ThOX/Duox genes and their 5?-flanking regions. Mol. Cell. Endocrinol. 214, 53-62 (2004).
-
(2004)
Mol. Cell. Endocrinol
, vol.214
, pp. 53-62
-
-
Pachucki, J.1
Wang, D.2
Christophe, D.3
Miot, F.4
-
40
-
-
20244385005
-
Dual oxidase2 is expressed all along the digestive tract
-
El Hassani, R. A. et al. Dual oxidase2 is expressed all along the digestive tract. Am. J. Physiol. Gastrointest. Liver Physiol. 288, G933-G942 (2005).
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.288
, pp. G933-G942
-
-
El Hassani, R.A.1
-
41
-
-
66849111512
-
Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells
-
Luxen, S. et al. Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells. J. Cell Sci. 122, 1238-1247 (2009).
-
(2009)
J. Cell Sci
, vol.122
, pp. 1238-1247
-
-
Luxen, S.1
-
42
-
-
65349172964
-
Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation
-
Morand, S. et al. Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation. FASEB J. 23, 1205-1218 (2009).
-
(2009)
FASEB J
, vol.23
, pp. 1205-1218
-
-
Morand, S.1
-
43
-
-
84866978507
-
Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia
-
Xu, C., Linderholm, A., Grasberger, H., Harper, R. W. Dual oxidase 2 bidirectional promoter polymorphisms confer differential immune responses in airway epithelia. Am. J. Respir. Cell. Mol. Biol. 47, 484-490 (2012).
-
(2012)
Am. J. Respir. Cell. Mol. Biol
, vol.47
, pp. 484-490
-
-
Xu, C.1
Linderholm, A.2
Grasberger, H.3
Harper, R.W.4
-
44
-
-
24044546151
-
Dual oxidase-2 has an intrinsic Ca2+dependent H2O2-generating activity
-
Ameziane-El-Hassani, R. et al. Dual oxidase-2 has an intrinsic Ca2+dependent H2O2-generating activity. J. Biol. Chem. 280, 30046-30054 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 30046-30054
-
-
Ameziane-El-Hassani, R.1
-
45
-
-
84924942012
-
The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release
-
Ueyama, T. et al. The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release. J. Biol. Chem. 290, 6495-6506 (2015).
-
(2015)
J. Biol. Chem
, vol.290
, pp. 6495-6506
-
-
Ueyama, T.1
-
46
-
-
84874841030
-
Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins
-
Meitzler, J. L., Hinde, S., Banfi, B., Nauseef, W. M., Ortiz de Montellano, P. R. Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins. J. Biol. Chem. 288, 7147-7157 (2013).
-
(2013)
J. Biol. Chem
, vol.288
, pp. 7147-7157
-
-
Meitzler, J.L.1
Hinde, S.2
Banfi, B.3
Nauseef, W.M.4
Ortiz De Montellano, P.R.5
-
47
-
-
78650061731
-
Functional consequences of dual oxidase-thyroperoxidase interaction at the plasma membrane
-
Fortunato, R. S. et al. Functional consequences of dual oxidase-thyroperoxidase interaction at the plasma membrane. J. Clin. Endocrinol. Metab. 95, 5403-5411 (2010).
-
(2010)
J. Clin. Endocrinol. Metab
, vol.95
, pp. 5403-5411
-
-
Fortunato, R.S.1
-
48
-
-
84937784976
-
When an intramolecular disulfide bridge governs the interaction of DUOX2 with its partner DUOXA2
-
Carre, A. et al. When an intramolecular disulfide bridge governs the interaction of DUOX2 with its partner DUOXA2. Antioxid. Redox Signal. 23, 724-733 (2015).
-
(2015)
Antioxid. Redox Signal
, vol.23
, pp. 724-733
-
-
Carre, A.1
-
49
-
-
75149131560
-
Association of duoxes with thyroid peroxidase and its regulation in thyrocytes
-
Song, Y. et al. Association of duoxes with thyroid peroxidase and its regulation in thyrocytes. J. Clin. Endocrinol. Metab. 95, 375-382 (2010).
-
(2010)
J. Clin. Endocrinol. Metab
, vol.95
, pp. 375-382
-
-
Song, Y.1
-
50
-
-
65449180375
-
Activation of dual oxidases Duox1 and Duox2: Differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation
-
Rigutto, S. et al. Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation. J. Biol. Chem. 284, 6725-6734 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, pp. 6725-6734
-
-
Rigutto, S.1
-
51
-
-
0028224772
-
The human thyrotropin receptor activates G-proteins Gs and Gq/11
-
Allgeier, A. et al. The human thyrotropin receptor activates G-proteins Gs and Gq/11. J. Biol. Chem. 269, 13733-13735 (1994).
-
(1994)
J. Biol. Chem
, vol.269
, pp. 13733-13735
-
-
Allgeier, A.1
-
52
-
-
0041328169
-
An outline of inherited disorders of the thyroid hormone generating system
-
Knobel, M., Medeiros-Neto, G. An outline of inherited disorders of the thyroid hormone generating system. Thyroid 13, 771-801 (2003).
-
(2003)
Thyroid
, vol.13
, pp. 771-801
-
-
Knobel, M.1
Medeiros-Neto, G.2
-
53
-
-
0025905588
-
Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices
-
Laurent, E. et al. Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices. J. Clin. Invest. 87, 1634-1642 (1991).
-
(1991)
J. Clin. Invest
, vol.87
, pp. 1634-1642
-
-
Laurent, E.1
-
54
-
-
0026499881
-
Thyroid expression of an A2 adenosine receptor transgene induces thyroid hyperplasia and hyperthyroidism
-
Ledent, C., Dumont, J. E., Vassart, G., Parmentier, M. Thyroid expression of an A2 adenosine receptor transgene induces thyroid hyperplasia and hyperthyroidism. EMBO J. 11, 537-542 (1992).
-
(1992)
EMBO J
, vol.11
, pp. 537-542
-
-
Ledent, C.1
Dumont, J.E.2
Vassart, G.3
Parmentier, M.4
-
55
-
-
0031035909
-
Costimulation of adenylyl cyclase and phospholipase C by a mutant ? 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells
-
Ledent, C. et al. Costimulation of adenylyl cyclase and phospholipase C by a mutant ? 1B-adrenergic receptor transgene promotes malignant transformation of thyroid follicular cells. Endocrinology 138, 369-378 (1997).
-
(1997)
Endocrinology
, vol.138
, pp. 369-378
-
-
Ledent, C.1
-
56
-
-
0017665385
-
Human thyroid peroxidase activity in benign and malign thyroid disorders
-
Fragu, P., Nataf, B. M. Human thyroid peroxidase activity in benign and malign thyroid disorders. J. Clin. Endocrinol. Metab. 45, 1089-1096 (1977).
-
(1977)
J. Clin. Endocrinol. Metab
, vol.45
, pp. 1089-1096
-
-
Fragu, P.1
Nataf, B.M.2
-
57
-
-
0034853752
-
Ca2 adenine dinucleotide phosphate-dependent H2O2 generation is inhibited by iodide in human thyroids
-
Cardoso, L. C. et al. Ca2 adenine dinucleotide phosphate-dependent H2O2 generation is inhibited by iodide in human thyroids. J. Clin. Endocrinol. Metab. 86, 4339-4343 (2001).
-
(2001)
J. Clin. Endocrinol. Metab
, vol.86
, pp. 4339-4343
-
-
Cardoso, L.C.1
-
58
-
-
0034002093
-
Stimulation by iodide of H2O2 generation in thyroid slices from several species
-
Corvilain, B., Collyn, L., van Sande, J., Dumont, J. E. Stimulation by iodide of H2O2 generation in thyroid slices from several species. Am. J. Physiol. Endocrinol. Metab. 278, E692-E699 (2000).
-
(2000)
Am. J. Physiol. Endocrinol. Metab
, vol.278
, pp. E692-E699
-
-
Corvilain, B.1
Collyn, L.2
Van Sande, J.3
Dumont, J.E.4
-
59
-
-
0037390485
-
Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles
-
Morand, S. et al. Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles. Endocrinology 144, 1241-1248 (2003).
-
(2003)
Endocrinology
, vol.144
, pp. 1241-1248
-
-
Morand, S.1
-
60
-
-
8544270180
-
Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase
-
Ambasta, R. K. et al. Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase. J. Biol. Chem. 279, 45935-45941 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 45935-45941
-
-
Ambasta, R.K.1
-
61
-
-
69249246990
-
Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells
-
Lyle, A. N. et al. Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells. Circ. Res. 105, 249-259 (2009).
-
(2009)
Circ. Res
, vol.105
, pp. 249-259
-
-
Lyle, A.N.1
-
62
-
-
63849160230
-
Molecular mechanisms of hypertension: Role of Nox family NADPH oxidases
-
Sedeek, M., Hebert, R. L., Kennedy, C. R., Burns, K. D., Touyz, R. M. Molecular mechanisms of hypertension: role of Nox family NADPH oxidases. Curr. Opin. Nephrol. Hypertens. 18, 122-127 (2009).
-
(2009)
Curr. Opin. Nephrol. Hypertens
, vol.18
, pp. 122-127
-
-
Sedeek, M.1
Hebert, R.L.2
Kennedy, C.R.3
Burns, K.D.4
Touyz, R.M.5
-
63
-
-
0038148216
-
Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells
-
Gorin, Y. et al. Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells. Am. J. Physiol. Renal Physiol. 285, F219-F229 (2003).
-
(2003)
Am. J. Physiol. Renal Physiol
, vol.285
, pp. F219-F229
-
-
Gorin, Y.1
-
64
-
-
79953881843
-
The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4
-
Takac, I. et al. The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4. J. Biol. Chem. 286, 13304-13313 (2011).
-
(2011)
J. Biol. Chem
, vol.286
, pp. 13304-13313
-
-
Takac, I.1
-
65
-
-
70149091965
-
Subcellular localization of Nox4 and regulation in diabetes
-
Block, K., Gorin, Y., Abboud, H. E. Subcellular localization of Nox4 and regulation in diabetes. Proc. Natl Acad. Sci. USA 106, 14385-14390 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 14385-14390
-
-
Block, K.1
Gorin, Y.2
Abboud, H.E.3
-
66
-
-
84907367024
-
N?-carboxymethyllysine-mediated endoplasmic reticulum stress promotes endothelial cell injury through Nox4/MKP-3 interaction
-
Lee, W. J. et al. N?-carboxymethyllysine-mediated endoplasmic reticulum stress promotes endothelial cell injury through Nox4/MKP-3 interaction. Free Radic. Biol. Med. 74, 294-306 (2014).
-
(2014)
Free Radic. Biol. Med
, vol.74
, pp. 294-306
-
-
Lee, W.J.1
-
67
-
-
79953183600
-
Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4
-
Spencer, N. Y. et al. Control of hepatic nuclear superoxide production by glucose 6-phosphate dehydrogenase and NADPH oxidase-4. J. Biol. Chem. 286, 8977-8987 (2011).
-
(2011)
J. Biol. Chem
, vol.286
, pp. 8977-8987
-
-
Spencer, N.Y.1
-
68
-
-
84910680242
-
Clinical genetics of congenital hypothyroidism
-
Szinnai, G. Clinical genetics of congenital hypothyroidism. Endocr. Dev. 26, 60-78 (2014).
-
(2014)
Endocr. Dev
, vol.26
, pp. 60-78
-
-
Szinnai, G.1
-
69
-
-
0037063119
-
Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism
-
Moreno, J. C. et al. Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism. N. Engl. J. Med. 347, 95-102 (2002).
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 95-102
-
-
Moreno, J.C.1
-
70
-
-
80655134848
-
Molecular basis of thyroid dyshormonogenesis: Genetic screening in population-based Japanese patients
-
Narumi, S., Muroya, K., Asakura, Y., Aachi, M., Hasegawa, T. Molecular basis of thyroid dyshormonogenesis: genetic screening in population-based Japanese patients. J. Clin. Endocrinol. Metab. 96, E1838-E1842 (2011).
-
(2011)
J. Clin. Endocrinol. Metab
, vol.96
, pp. E1838-E1842
-
-
Narumi, S.1
Muroya, K.2
Asakura, Y.3
Aachi, M.4
Hasegawa, T.5
-
71
-
-
39049092782
-
Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism
-
Zamproni, I. et al. Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism. J. Clin. Endocrinol. Metab. 93, 605-610 (2008).
-
(2008)
J. Clin. Endocrinol. Metab
, vol.93
, pp. 605-610
-
-
Zamproni, I.1
-
72
-
-
78650132026
-
Urothelial cells produce hydrogen peroxide through the activation of Duox1
-
Donko, A. et al. Urothelial cells produce hydrogen peroxide through the activation of Duox1. Free Radic. Biol. Med. 49, 2040-2048 (2010).
-
(2010)
Free Radic. Biol. Med
, vol.49
, pp. 2040-2048
-
-
Donko, A.1
-
73
-
-
34347208727
-
Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2
-
Johnson, K. R. et al. Congenital hypothyroidism, dwarfism, and hearing impairment caused by a missense mutation in the mouse dual oxidase 2 gene, Duox2. Mol. Endocrinol. 21, 1593-1602 (2007).
-
(2007)
Mol. Endocrinol
, vol.21
, pp. 1593-1602
-
-
Johnson, K.R.1
-
74
-
-
84857466174
-
Mice deficient in dual oxidase maturation factors are severely hypothyroid
-
Grasberger, H. et al. Mice deficient in dual oxidase maturation factors are severely hypothyroid. Mol. Endocrinol. 26, 481-492 (2012).
-
(2012)
Mol. Endocrinol
, vol.26
, pp. 481-492
-
-
Grasberger, H.1
-
75
-
-
0035893558
-
Hydrogen peroxide-induced production of a 40 kDa immunoreactive thyroglobulin fragment in human thyroid cells: The onset of thyroid autoimmunity
-
Duthoit, C. et al. Hydrogen peroxide-induced production of a 40 kDa immunoreactive thyroglobulin fragment in human thyroid cells: the onset of thyroid autoimmunity? Biochem. J. 360, 557-562 (2001).
-
(2001)
Biochem. J
, vol.360
, pp. 557-562
-
-
Duthoit, C.1
-
76
-
-
2942620244
-
Antigenicity and immunogenicity of the C-terminal peptide of human thyroglobulin
-
El Hassani, R. A. et al. Antigenicity and immunogenicity of the C-terminal peptide of human thyroglobulin. Peptides 25, 1021-1029 (2004).
-
(2004)
Peptides
, vol.25
, pp. 1021-1029
-
-
El Hassani, R.A.1
-
77
-
-
15744401552
-
Peroxiredoxin 5 expression in the human thyroid gland
-
Gerard, A. C., Many, M. C., Daumerie, C., Knoops, B., Colin, I. M. Peroxiredoxin 5 expression in the human thyroid gland. Thyroid 15, 205-209 (2005).
-
(2005)
Thyroid
, vol.15
, pp. 205-209
-
-
Gerard, A.C.1
Many, M.C.2
Daumerie, C.3
Knoops, B.4
Colin, I.M.5
-
78
-
-
77954606305
-
N-acetylcysteine and 15 deoxy-?12,14-prostaglandin J2 exert a protective effect against autoimmune thyroid destruction in vivo but not against interleukin-1?/interferon ?-induced inhibitory effects in thyrocytes in vitro
-
Poncin, S. et al. N-acetylcysteine and 15 deoxy-?12,14-prostaglandin J2 exert a protective effect against autoimmune thyroid destruction in vivo but not against interleukin-1?/interferon ?-induced inhibitory effects in thyrocytes in vitro. Am. J. Pathol. 177, 219-228 (2010).
-
(2010)
Am. J. Pathol
, vol.177
, pp. 219-228
-
-
Poncin, S.1
-
79
-
-
84874109230
-
Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2
-
Raad, H., Eskalli, Z., Corvilain, B., Miot, F., De Deken, X. Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2. Free Radic. Biol. Med. 56, 216-225 (2013).
-
(2013)
Free Radic. Biol. Med
, vol.56
, pp. 216-225
-
-
Raad, H.1
Eskalli, Z.2
Corvilain, B.3
Miot, F.4
De Deken, X.5
-
80
-
-
84899967474
-
The expression of dual oxidase, thyroid peroxidase, and caveolin-1 differs according to the type of immune response (TH1/TH2) involved in thyroid autoimmune disorders
-
Marique, L. et al. The expression of dual oxidase, thyroid peroxidase, and caveolin-1 differs according to the type of immune response (TH1/TH2) involved in thyroid autoimmune disorders. J. Clin. Endocrinol. Metab. 99, 1722-1732 (2014).
-
(2014)
J. Clin. Endocrinol. Metab
, vol.99
, pp. 1722-1732
-
-
Marique, L.1
-
81
-
-
67650151005
-
Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
-
Colotta, F., Allavena, P., Sica, A., Garlanda, C., Mantovani, A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30, 1073-1081 (2009).
-
(2009)
Carcinogenesis
, vol.30
, pp. 1073-1081
-
-
Colotta, F.1
Allavena, P.2
Sica, A.3
Garlanda, C.4
Mantovani, A.5
-
82
-
-
77950958227
-
Thyroid cancer and inflammation
-
Guarino, V., Castellone, M. D., Avilla, E., Melillo, R. M. Thyroid cancer and inflammation. Mol. Cell. Endocrinol. 321, 94-102 (2010).
-
(2010)
Mol. Cell. Endocrinol
, vol.321
, pp. 94-102
-
-
Guarino, V.1
Castellone, M.D.2
Avilla, E.3
Melillo, R.M.4
-
83
-
-
33744962523
-
RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: Follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma
-
Rhoden, K. J. et al. RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma. J. Clin. Endocrinol. Metab. 91, 2414-2423 (2006).
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, pp. 2414-2423
-
-
Rhoden, K.J.1
-
84
-
-
80053150200
-
Molecular genetics and diagnosis of thyroid cancer
-
Nikiforov, Y. E., Nikiforova, M. N. Molecular genetics and diagnosis of thyroid cancer. Nat. Rev. Endocrinol. 7, 569-580 (2011).
-
(2011)
Nat. Rev. Endocrinol
, vol.7
, pp. 569-580
-
-
Nikiforov, Y.E.1
Nikiforova, M.N.2
-
85
-
-
77952794328
-
Role of H2O2 in RET/PTC1 chromosomal rearrangement produced by ionizing radiation in human thyroid cells
-
Ameziane-El-Hassani, R. et al. Role of H2O2 in RET/PTC1 chromosomal rearrangement produced by ionizing radiation in human thyroid cells. Cancer Res. 70, 4123-4132 (2010).
-
(2010)
Cancer Res
, vol.70
, pp. 4123-4132
-
-
Ameziane-El-Hassani, R.1
-
86
-
-
72749107885
-
Hydrogen peroxide induces DNA single-and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ
-
Driessens, N. et al. Hydrogen peroxide induces DNA single-and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ. Endocr. Relat. Cancer 16, 845-856 (2009).
-
(2009)
Endocr. Relat. Cancer
, vol.16
, pp. 845-856
-
-
Driessens, N.1
-
87
-
-
77951977494
-
Role of oxidatively induced DNA lesions in human pathogenesis
-
Sedelnikova, O. A. et al. Role of oxidatively induced DNA lesions in human pathogenesis. Mutat. Res. 704, 152-159 (2010).
-
(2010)
Mutat. Res
, vol.704
, pp. 152-159
-
-
Sedelnikova, O.A.1
-
88
-
-
84861139727
-
Distinct pattern of oxidative DNA damage and DNA repair in follicular thyroid tumours
-
Karger, S. et al. Distinct pattern of oxidative DNA damage and DNA repair in follicular thyroid tumours. J. Mol. Endocrinol. 48, 193-202 (2012).
-
(2012)
J. Mol. Endocrinol
, vol.48
, pp. 193-202
-
-
Karger, S.1
-
90
-
-
84917673867
-
No association between XRCC1 genetic polymorphisms and differentiated thyroid carcinoma risk: A meta-analysis
-
Li, C., Xiang, X., Zhou, Y. No association between XRCC1 genetic polymorphisms and differentiated thyroid carcinoma risk: a meta-analysis. Mol. Biol. Rep. 41, 7613-7621 (2014).
-
(2014)
Mol. Biol. Rep
, vol.41
, pp. 7613-7621
-
-
Li, C.1
Xiang, X.2
Zhou, Y.3
-
91
-
-
84902985518
-
Association of XRCC1 polymorphisms with thyroid cancer risk
-
Wang, C., Ai, Z. Association of XRCC1 polymorphisms with thyroid cancer risk. Tumour Biol. 35, 4791-4797 (2014).
-
(2014)
Tumour Biol
, vol.35
, pp. 4791-4797
-
-
Wang, C.1
Ai, Z.2
-
92
-
-
84867452253
-
3rd Pathways for repairing and tolerating the spectrum of oxidative DNA lesions
-
Berquist, B. R., Wilson, D. M. 3rd Pathways for repairing and tolerating the spectrum of oxidative DNA lesions. Cancer Lett. 327, 61-72 (2012).
-
(2012)
Cancer Lett
, vol.327
, pp. 61-72
-
-
Berquist, B.R.1
Wilson, D.M.2
-
93
-
-
0034621854
-
Frequent chromosomal translocations induced by DNA double-strand breaks
-
Richardson, C., Jasin, M. Frequent chromosomal translocations induced by DNA double-strand breaks. Nature 405, 697-700 (2000).
-
(2000)
Nature
, vol.405
, pp. 697-700
-
-
Richardson, C.1
Jasin, M.2
-
94
-
-
0028825189
-
RET/PTC oncogene activation is an early event in thyroid carcinogenesis
-
Viglietto, G. et al. RET/PTC oncogene activation is an early event in thyroid carcinogenesis. Oncogene 11, 1207-1210 (1995).
-
(1995)
Oncogene
, vol.11
, pp. 1207-1210
-
-
Viglietto, G.1
-
95
-
-
84885214495
-
Comparative analysis of the thyrocytes and T cells: Responses to H2O2 and radiation reveals an H2O2-induced antioxidant transcriptional program in thyrocytes
-
Versteyhe, S. et al. Comparative analysis of the thyrocytes and T cells: responses to H2O2 and radiation reveals an H2O2-induced antioxidant transcriptional program in thyrocytes. J. Clin. Endocrinol. Metab. 98, E1645-E1654 (2013).
-
(2013)
J. Clin. Endocrinol. Metab
, vol.98
, pp. E1645-E1654
-
-
Versteyhe, S.1
-
96
-
-
0036488604
-
Second cancers in survivors of childhood cancer
-
Bhatia, S., Sklar, C. Second cancers in survivors of childhood cancer. Nat. Rev. Cancer 2, 124-132 (2002).
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 124-132
-
-
Bhatia, S.1
Sklar, C.2
-
97
-
-
33750603975
-
Long-term risks for thyroid cancer and other neoplasms after exposure to radiation
-
Schneider, A. B., Sarne, D. H. Long-term risks for thyroid cancer and other neoplasms after exposure to radiation. Nat. Clin. Pract. Endocrinol. Metab. 1, 82-91 (2005).
-
(2005)
Nat. Clin. Pract. Endocrinol. Metab
, vol.1
, pp. 82-91
-
-
Schneider, A.B.1
Sarne, D.H.2
-
98
-
-
84867483822
-
Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury
-
Azzam, E. I., Jay-Gerin, J. P., Pain, D. Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury. Cancer Lett. 327, 48-60 (2012).
-
(2012)
Cancer Lett
, vol.327
, pp. 48-60
-
-
Azzam, E.I.1
Jay-Gerin, J.P.2
Pain, D.3
-
99
-
-
0033646576
-
Hypoxia relieves X-ray-induced delayed effects in normal human embryo cells
-
Roy, K., Kodama, S., Suzuki, K., Fukase, K., Watanabe, M. Hypoxia relieves X-ray-induced delayed effects in normal human embryo cells. Radiat. Res. 154, 659-666 (2000).
-
(2000)
Radiat. Res
, vol.154
, pp. 659-666
-
-
Roy, K.1
Kodama, S.2
Suzuki, K.3
Fukase, K.4
Watanabe, M.5
-
100
-
-
0242406772
-
Radiation-induced DNA damage and delayed induced genomic instability
-
Suzuki, K., Ojima, M., Kodama, S., Watanabe, M. Radiation-induced DNA damage and delayed induced genomic instability. Oncogene 22, 6988-6993 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 6988-6993
-
-
Suzuki, K.1
Ojima, M.2
Kodama, S.3
Watanabe, M.4
-
101
-
-
0242490151
-
Radiation-induced genomic instability and bystander effects: Inter-related nontargeted effects of exposure to ionizing radiation
-
Lorimore, S. A., Coates, P. J., Wright, E. G. Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation. Oncogene 22, 7058-7069 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 7058-7069
-
-
Lorimore, S.A.1
Coates, P.J.2
Wright, E.G.3
-
102
-
-
84907212782
-
Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage
-
Cleaver, J. E. et al. Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage. Proc. Natl Acad. Sci. USA 111, 13487-13492 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 13487-13492
-
-
Cleaver, J.E.1
-
103
-
-
84901025723
-
Mucosal reactive oxygen species are required for antiviral response: Role of Duox in influenza a virus infection
-
Strengert, M. et al. Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection. Antioxid. Redox Signal. 20, 2695-2709 (2014).
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 2695-2709
-
-
Strengert, M.1
-
104
-
-
34548588388
-
Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers
-
Detours, V. et al. Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers. Br. J. Cancer 97, 818-825 (2007).
-
(2007)
Br. J. Cancer
, vol.97
, pp. 818-825
-
-
Detours, V.1
-
105
-
-
84865866443
-
A gene expression signature distinguishes normal tissues of sporadic and radiation-induced papillary thyroid carcinomas
-
Dom, G. et al. A gene expression signature distinguishes normal tissues of sporadic and radiation-induced papillary thyroid carcinomas. Br. J. Cancer 107, 994-1000 (2012).
-
(2012)
Br. J. Cancer
, vol.107
, pp. 994-1000
-
-
Dom, G.1
-
106
-
-
0035185319
-
Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas
-
Lacroix, L. et al. Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas. Thyroid 11, 1017-1023 (2001).
-
(2001)
Thyroid
, vol.11
, pp. 1017-1023
-
-
Lacroix, L.1
-
107
-
-
84924350333
-
Epigenetic silencing of dual oxidase 1 by promoter hypermethylation in human hepatocellular carcinoma
-
Ling, Q. et al. Epigenetic silencing of dual oxidase 1 by promoter hypermethylation in human hepatocellular carcinoma. Am. J. Cancer Res. 4, 508-517 (2014).
-
(2014)
Am. J. Cancer Res
, vol.4
, pp. 508-517
-
-
Ling, Q.1
-
108
-
-
39449091629
-
Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer
-
Luxen, S., Belinsky, S. A., Knaus, U. G. Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer. Cancer Res. 68, 1037-1045 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 1037-1045
-
-
Luxen, S.1
Belinsky, S.A.2
Knaus, U.G.3
-
109
-
-
84874642904
-
Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody
-
Wu, Y. et al. Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody. Int. J. Oncol. 42, 1229-1238 (2013).
-
(2013)
Int. J. Oncol
, vol.42
, pp. 1229-1238
-
-
Wu, Y.1
-
110
-
-
33750533387
-
ROS as a tumour suppressor? Nat
-
Ramsey, M. R., Sharpless, N. E. ROS as a tumour suppressor? Nat. Cell Biol. 8, 1213-1215 (2006).
-
(2006)
Cell Biol
, vol.8
, pp. 1213-1215
-
-
Ramsey, M.R.1
Sharpless, N.E.2
-
111
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova, J. et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444, 633-637 (2006).
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
-
112
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee, A. C. et al. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J. Biol. Chem. 274, 7936-7940 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
-
113
-
-
0036285034
-
C-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
-
Vafa, O. et al. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol. Cell 9, 1031-1044 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 1031-1044
-
-
Vafa, O.1
-
114
-
-
84891301320
-
Causes and consequences of replication stress
-
Zeman, M. K., Cimprich, K. A. Causes and consequences of replication stress. Nat. Cell Biol. 16, 2-9 (2014).
-
(2014)
Nat. Cell Biol
, vol.16
, pp. 2-9
-
-
Zeman, M.K.1
Cimprich, K.A.2
-
115
-
-
84899929645
-
Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
-
Ogrunc, M. et al. Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation. Cell Death Differ. 21, 998-1012 (2014).
-
(2014)
Cell Death Differ
, vol.21
, pp. 998-1012
-
-
Ogrunc, M.1
-
116
-
-
84908027700
-
Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction
-
Xu, B. et al. Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction. Mutat. Res. 770, 1-8 (2014).
-
(2014)
Mutat. Res
, vol.770
, pp. 1-8
-
-
Xu, B.1
-
117
-
-
84898987305
-
Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells
-
Mishra, P. K. et al. Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells. Int. J. Toxicol. 33, 116-129 (2014).
-
(2014)
Int. J. Toxicol
, vol.33
, pp. 116-129
-
-
Mishra, P.K.1
-
118
-
-
81255162523
-
Oxidative damage targets complexes containing DNA methyltransferases SIRT1, and polycomb members to promoter CpG Islands
-
O'Hagan, H. M. et al. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands. Cancer Cell 20, 606-619 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 606-619
-
-
O'Hagan, H.M.1
-
119
-
-
84978849685
-
-
Ch.2 (eds Groot, L. J. et al.) (South Dartmouth
-
Miot, F., Dupuy, C., Dumont, J., Rousset, B. Endotext Ch.2 (eds Groot, L. J. et al.) (South Dartmouth, 2000)
-
(2000)
-
-
Miot, F.1
Dupuy, C.2
Dumont, J.3
Endotext, R.B.4
-
120
-
-
84934904648
-
Aquaporin-3-mediated hydrogen peroxide transport is required for NF-?B signalling in keratinocytes and development of psoriasis
-
Hara-Chikuma, M. et al. Aquaporin-3-mediated hydrogen peroxide transport is required for NF-?B signalling in keratinocytes and development of psoriasis. Nat. Commun. 6, 7454 (2015).
-
(2015)
Nat. Commun
, vol.6
, pp. 7454
-
-
Hara-Chikuma, M.1
-
121
-
-
84877001084
-
Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence
-
Aird, K. M. et al. Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence. Cell Rep. 3, 1252-1265 (2013).
-
(2013)
Cell Rep
, vol.3
, pp. 1252-1265
-
-
Aird, K.M.1
-
122
-
-
79955525482
-
Nucleotide deficiency promotes genomic instability in early stages of cancer development
-
Bester, A. C. et al. Nucleotide deficiency promotes genomic instability in early stages of cancer development. Cell 145, 435-446 (2011).
-
(2011)
Cell
, vol.145
, pp. 435-446
-
-
Bester, A.C.1
-
123
-
-
84949293830
-
Singlet oxygen-mediated oxidation during UVA radiation alters the dynamic of genomic DNA replication
-
Graindorge, D. et al. Singlet oxygen-mediated oxidation during UVA radiation alters the dynamic of genomic DNA replication. PLoS ONE 10, e0140645 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0140645
-
-
Graindorge, D.1
-
124
-
-
77951060421
-
DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells
-
Gandhi, M., Dillon, L. W., Pramanik, S., Nikiforov, Y. E., Wang, Y. H. DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells. Oncogene 29, 2272-2280 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 2272-2280
-
-
Gandhi, M.1
Dillon, L.W.2
Pramanik, S.3
Nikiforov, Y.E.4
Wang, Y.H.5
-
125
-
-
79955036320
-
Dual oxidase 1 induced by Th2 cytokines promotes STAT6 phosphorylation via oxidative inactivation of protein tyrosine phosphatase 1B in human epidermal keratinocytes
-
Hirakawa, S., Saito, R., Ohara, H., Okuyama, R., Aiba, S. Dual oxidase 1 induced by Th2 cytokines promotes STAT6 phosphorylation via oxidative inactivation of protein tyrosine phosphatase 1B in human epidermal keratinocytes. J. Immunol. 186, 4762-4770 (2011).
-
(2011)
J. Immunol
, vol.186
, pp. 4762-4770
-
-
Hirakawa, S.1
Saito, R.2
Ohara, H.3
Okuyama, R.4
Aiba, S.5
|