메뉴 건너뛰기




Volumn 463, Issue 4, 2015, Pages 839-845

PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma

Author keywords

DUOX2; Hepatocellular carcinoma; PKC ; Reactive oxygen species

Indexed keywords

DUOX2 ENZYME; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA I; PROTEIN KINASE C BETA II; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; DUOX2 PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84936986307     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.06.021     Document Type: Article
Times cited : (16)

References (37)
  • 3
  • 5
    • 0029060391 scopus 로고
    • Protein kinases.5. Protein-Kinase-C and lipid signaling for sustained cellular-responses
    • Y. Nishizuka Protein kinases.5. Protein-Kinase-C and lipid signaling for sustained cellular-responses Faseb J. 9 1995 484 496
    • (1995) Faseb J. , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 6
    • 33947603008 scopus 로고    scopus 로고
    • Protein kinase C and other diacylglycerol effectors in cancer
    • E.M. Griner, and M.G. Kazanietz Protein kinase C and other diacylglycerol effectors in cancer Nat. Rev. Cancer 7 2007 281 294
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 281-294
    • Griner, E.M.1    Kazanietz, M.G.2
  • 7
    • 0036855463 scopus 로고    scopus 로고
    • Protein kinase C alpha (PKC alpha): Regulation and biological function
    • S. Nakashima Protein kinase C alpha (PKC alpha): regulation and biological function J. Biochem. 132 2002 669 675
    • (2002) J. Biochem. , vol.132 , pp. 669-675
    • Nakashima, S.1
  • 8
    • 0024323584 scopus 로고
    • Elevated protein kinase-C expression in human-breast tumor-biopsies relative to normal breast-tissue
    • C.A. Obrian, V.G. Vogel, S.E. Singletary, and N.E. Ward Elevated protein kinase-C expression in human-breast tumor-biopsies relative to normal breast-tissue Cancer Res. 49 1989 3215 3217
    • (1989) Cancer Res. , vol.49 , pp. 3215-3217
    • Obrian, C.A.1    Vogel, V.G.2    Singletary, S.E.3    Ward, N.E.4
  • 9
    • 0028566097 scopus 로고
    • Involvement of the alpha-isoenzyme of protein-kinase-C in the growth-inhibition induced by phorbol esters in Mh1c1 hepatoma-cells
    • G.P. Perletti, C. Smeraldi, D. Porro, and F. Piccinini Involvement of the alpha-isoenzyme of protein-kinase-C in the growth-inhibition induced by phorbol esters in Mh1c1 hepatoma-cells Biochem. Biophys. Res. Commun. 205 1994 1589 1594
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 1589-1594
    • Perletti, G.P.1    Smeraldi, C.2    Porro, D.3    Piccinini, F.4
  • 10
    • 0032489321 scopus 로고    scopus 로고
    • The protein kinase C activator, phorbol ester, elicits disparate functional responses in androgen-sensitive and androgen-independent human prostatic cancer cells
    • P. Henttu, and P. Vihko The protein kinase C activator, phorbol ester, elicits disparate functional responses in androgen-sensitive and androgen-independent human prostatic cancer cells Biochem. Biophys. Res. Commun. 244 1998 167 171
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 167-171
    • Henttu, P.1    Vihko, P.2
  • 11
    • 34249099952 scopus 로고    scopus 로고
    • Overexpression of protein kinase C alpha mRNA in human hepatocellular carcinoma: A potential marker of disease prognosis
    • T.T. Wu, Y.H. Hsieh, C.C. Wu, Y.S. Hsieh, C.Y. Huang, and J.Y. Liu Overexpression of protein kinase C alpha mRNA in human hepatocellular carcinoma: a potential marker of disease prognosis Clin. Chim. Acta 382 2007 54 58
    • (2007) Clin. Chim. Acta , vol.382 , pp. 54-58
    • Wu, T.T.1    Hsieh, Y.H.2    Wu, C.C.3    Hsieh, Y.S.4    Huang, C.Y.5    Liu, J.Y.6
  • 14
    • 84901052694 scopus 로고    scopus 로고
    • ROS function in redox signaling and oxidative stress
    • M. Schieber, and N.S. Chandel ROS function in redox signaling and oxidative stress Curr. Biol. 24 2014 R453 R462
    • (2014) Curr. Biol. , vol.24 , pp. R453-R462
    • Schieber, M.1    Chandel, N.S.2
  • 15
    • 1542406446 scopus 로고    scopus 로고
    • NOX enzymes and the biology of reactive oxygen
    • J.D. Lambeth NOX enzymes and the biology of reactive oxygen Nat. Rev. Immunol. 4 2004 181 189
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 181-189
    • Lambeth, J.D.1
  • 16
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • K. Bedard, and K.H. Krause The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology Physiol. Rev. 87 2007 245 313
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 19
    • 77951279075 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer
    • G.Y. Liou, and P. Storz Reactive oxygen species in cancer Free Radic. Res. 44 2010 479 496
    • (2010) Free Radic. Res. , vol.44 , pp. 479-496
    • Liou, G.Y.1    Storz, P.2
  • 23
    • 84936985104 scopus 로고    scopus 로고
    • Protein kinase C (PKC) isozymes and cancer
    • J.-H. Kang Protein kinase C (PKC) isozymes and cancer New J. Sci. 2014 2014 1 36
    • (2014) New J. Sci. , vol.2014 , pp. 1-36
    • Kang, J.-H.1
  • 24
    • 25844507931 scopus 로고    scopus 로고
    • PKC delta mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: Possible involvement of PKC delta in vascular hypertrophy
    • C.Y. Fan, M. Katsuyama, and C. Yabe-Nishimura PKC delta mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKC delta in vascular hypertrophy Biochem. J. 390 2005 761 767
    • (2005) Biochem. J. , vol.390 , pp. 761-767
    • Fan, C.Y.1    Katsuyama, M.2    Yabe-Nishimura, C.3
  • 25
    • 84936985605 scopus 로고    scopus 로고
    • High glucose-induced activation of PKC epsilon decreases the expression of bone morphogenetic protein 4 (Bmp4) and NADPH oxidase 4 (Nox4) through MAPK-dependent pathway in cultured mouse mesangial cells
    • N. Osawa, T. Hayashi, T. Uzu, T. Babazono, S. Babazono, Y. Iwamoto, A. Kashiwagi, and S. Maeda High glucose-induced activation of PKC epsilon decreases the expression of bone morphogenetic protein 4 (Bmp4) and NADPH oxidase 4 (Nox4) through MAPK-dependent pathway in cultured mouse mesangial cells Diabetes 56 2007 A200-A200
    • (2007) Diabetes , vol.56 , pp. A200-A200
    • Osawa, N.1    Hayashi, T.2    Uzu, T.3    Babazono, T.4    Babazono, S.5    Iwamoto, Y.6    Kashiwagi, A.7    Maeda, S.8
  • 27
    • 33750590656 scopus 로고    scopus 로고
    • Reactive oxygen species mediated sustained activation of protein kinase C alpha and extracellular signal-regulated kinase for migration of human hepatoma cell Hepg2
    • W.S. Wu, R.K. Tsai, C.H. Chang, S. Wang, J.R. Wu, and Y.X. Chang Reactive oxygen species mediated sustained activation of protein kinase C alpha and extracellular signal-regulated kinase for migration of human hepatoma cell Hepg2 Mol. Cancer Res. 4 2006 747 758
    • (2006) Mol. Cancer Res. , vol.4 , pp. 747-758
    • Wu, W.S.1    Tsai, R.K.2    Chang, C.H.3    Wang, S.4    Wu, J.R.5    Chang, Y.X.6
  • 28
    • 65449180375 scopus 로고    scopus 로고
    • Activation of Dual Oxidases Duox1 and Duox2 differential regulation mediated by camp-dependent protein kinase and protein kinase c-dependent phosphorylation
    • S. Rigutto, C. Hoste, H. Grasberger, M. Milenkovic, D. Communi, J.E. Dumont, B. Corvilain, F. Miot, and X. De Deken Activation of Dual Oxidases Duox1 and Duox2 differential regulation mediated by camp-dependent protein kinase and protein kinase c-dependent phosphorylation J. Biol. Chem. 284 2009 6725 6734
    • (2009) J. Biol. Chem. , vol.284 , pp. 6725-6734
    • Rigutto, S.1    Hoste, C.2    Grasberger, H.3    Milenkovic, M.4    Communi, D.5    Dumont, J.E.6    Corvilain, B.7    Miot, F.8    De Deken, X.9
  • 30
    • 2442543262 scopus 로고    scopus 로고
    • The role of protein kinase C-alpha (PKC-alpha) in cancer and its modulation by the novel PWC-alpha-specific inhibitor aprinocarsen
    • A.R. Hanauske, K. Sundell, and M. Lahn The role of protein kinase C-alpha (PKC-alpha) in cancer and its modulation by the novel PWC-alpha-specific inhibitor aprinocarsen Curr. Pharm. Des. 10 2004 1923 1936
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 1923-1936
    • Hanauske, A.R.1    Sundell, K.2    Lahn, M.3
  • 31
    • 38149132242 scopus 로고    scopus 로고
    • Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma
    • T.T. Wu, Y.H. Hsieh, Y.S. Hsieh, and J.Y. Liu Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma J. Cell. Biochem. 103 2008 9 20
    • (2008) J. Cell. Biochem. , vol.103 , pp. 9-20
    • Wu, T.T.1    Hsieh, Y.H.2    Hsieh, Y.S.3    Liu, J.Y.4
  • 32
    • 34250703569 scopus 로고    scopus 로고
    • Classical PKC isoforms in cancer
    • G. Martiny-Baron, and D. Fabbro Classical PKC isoforms in cancer Pharmacol. Res. 55 2007 477 486
    • (2007) Pharmacol. Res. , vol.55 , pp. 477-486
    • Martiny-Baron, G.1    Fabbro, D.2
  • 35
    • 45749108203 scopus 로고    scopus 로고
    • Transarterial chemoembolization for patients with hepatocellular carcinoma
    • A. Forner, M.I. Real, M. Varela, and J. Bruix Transarterial chemoembolization for patients with hepatocellular carcinoma Hepatol. Res. 37 2007 S230 S237
    • (2007) Hepatol. Res. , vol.37 , pp. S230-S237
    • Forner, A.1    Real, M.I.2    Varela, M.3    Bruix, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.