NOX5-L can stimulate proliferation and apoptosis depending on its levels and cellular context, determining cancer cell susceptibility to cisplatin

Oncotarget

Volumn 6, Issue 36, 2015, Pages 39235-39246

  Dho, So Hee ^a,b   Kim, Ji Young ^a   Kwon, Eun Soo ^a   Lim, Jae Cheong ^b   Park, Sung Sup ^a   Kwon, Ki Sun ^a,c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Atomic Energy Research Institute   (South Korea)

^c University of Science and Technology (UST)   (South Korea)

Author keywords

c Abl; Cisplatin; CREB; NOX5 L; ROS

Indexed keywords

ABELSON KINASE; CALCIUM ION; CASPASE 3; CISPLATIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN NOX5 L; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; NOX5 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CALCIUM TRANSPORT; CANCER GROWTH; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LUNG CANCER CELL LINE; PROTEIN EXPRESSION; SKIN CANCER; UPREGULATION; BREAST NEOPLASMS; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; LUNG NEOPLASMS; METABOLISM; NEOPLASMS; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SKIN NEOPLASMS; TUMOR CELL LINE;

APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; HUMANS; LUNG NEOPLASMS; MEMBRANE PROTEINS; NADPH OXIDASE; NEOPLASMS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SKIN NEOPLASMS; TRANSFECTION; UP-REGULATION;

EID: 84948843956     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5743     Document Type: Article

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