Inhibition of Nox1 induces apoptosis by attenuating the AKT signaling pathway in oral squamous cell carcinoma cell lines

Oncology Reports

Volumn 36, Issue 5, 2016, Pages 2991-2998

  Ito, Kunihiro ^a,b   Ota, Akinobu ^b   Ono, Takayuki ^a   Nakaoka, Toshiki ^a   Wahiduzzaman, Md ^b   Karnan, Sivasundaram ^b   Konishi, Hiroyuki ^b   Furuhashi, Akifumi ^a   Hayashi, Tomio ^a   Yamada, Yoichi ^a   Hosokawa, Yoshitaka ^b   Kazaoka, Yoshiaki ^a  

^a AICHI MEDICAL UNIVERSITY HOSPITAL   (Japan)

^b AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

AKT; Apoptosis; NADPH oxidase; Oral squamous cell carcinoma; Reactive oxygen species

Indexed keywords

CISPLATIN; DUOX1 PROTEIN; DUOX2 PROTEIN; MESSENGER RNA; PERIFOSINE; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 5; UNCLASSIFIED DRUG; NOX1 PROTEIN, HUMAN; ONCOPROTEIN; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL SURVIVAL; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUTH SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BIOSYNTHESIS; CELL LINEAGE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUTH TUMOR; PATHOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL LINEAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOUTH NEOPLASMS; NADPH OXIDASE; ONCOGENE PROTEIN V-AKT; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84989879414     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2016.5068     Document Type: Article

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