-
1
-
-
0037388204
-
Prospective identification of tumorigenic breastcancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ,Clarke MF. (2003). Prospective identification of tumorigenic breastcancer cells. Proc Natl Acad Sci USA 100: 3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
2
-
-
0034802887
-
The p65 (RelA)subunit of NF-kappaB interacts with the histone deacetylase(HDAC) corepressors HDAC1 and HDAC2 to negatively regulategene expression
-
Ashburner BP, Westerheide SD, Baldwin Jr. S. (2001). The p65 (RelA)subunit of NF-kappaB interacts with the histone deacetylase(HDAC) corepressors HDAC1 and HDAC2 to negatively regulategene expression. Mol Cell Biol 21: 7065-7077.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7065-7077
-
-
Ashburner, B.P.1
Westerheide, S.D.2
Baldwin Jr., S.3
-
3
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stemcells
-
Banito A, Rashid ST, Acosta JC, Li S, Pereira CF, Geti I et al. (2009).Senescence impairs successful reprogramming to pluripotent stemcells. Genes Dev 23: 2134-2139.
-
(2009)
Genes Dev
, vol.23
, pp. 2134-2139
-
-
Banito, A.1
Rashid, S.T.2
Acosta, J.C.3
Li, S.4
Pereira, C.F.5
Geti, I.6
-
4
-
-
70350641014
-
SOX2 is an amplified lineage-survival oncogene in lung andesophageal squamous cell carcinomas
-
Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG et al.(2009). SOX2 is an amplified lineage-survival oncogene in lung andesophageal squamous cell carcinomas. Nat Genet 41: 1238-1242.
-
(2009)
Nat Genet
, vol.41
, pp. 1238-1242
-
-
Bass, A.J.1
Watanabe, H.2
Mermel, C.H.3
Yu, S.4
Perner, S.5
Verhaak, R.G.6
-
5
-
-
34250661903
-
Short silencing RNA: The dark matter ofgenetics?
-
Baulcombe DC. (2006). Short silencing RNA: the dark matter ofgenetics? Cold Spring Harb Symp Quant Biol 71: 13-20.
-
(2006)
Cold Spring Harb Symp Quant Biol
, vol.71
, pp. 13-20
-
-
Baulcombe, D.C.1
-
6
-
-
42649112047
-
An embryonic stem cell-like gene expression signaturein poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev Aet al. (2008). An embryonic stem cell-like gene expression signaturein poorly differentiated aggressive human tumors. Nat Genet 40:499-507.
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
-
7
-
-
0030789242
-
Human acute myeloid leukemia isorganized as a hierarchy that originates from a primitive hematopoieticcell
-
Bonnet D, Dick JE. (1997). Human acute myeloid leukemia isorganized as a hierarchy that originates from a primitive hematopoieticcell. Nat Med 3: 730-737.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
8
-
-
44649163918
-
A reciprocal repression between ZEB1 and members ofthe miR-200 family promotes EMT and invasion in cancer cells
-
Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna Set al. (2008). A reciprocal repression between ZEB1 and members ofthe miR-200 family promotes EMT and invasion in cancer cells.EMBO Rep 9: 582-589.
-
(2008)
EMBO Rep
, vol.9
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
Schmalhofer, O.4
Vincan, E.5
Spaderna, S.6
-
9
-
-
33847063053
-
The triple negative paradox: Primary tumor chemosensitivityof breast cancer subtypes
-
Carey LA, Dees EC, Sawyer L, Gatti L, Moore DT, Collichio F et al.(2007). The triple negative paradox: primary tumor chemosensitivityof breast cancer subtypes. Clin Cancer Res 13: 2329-2334.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
Gatti, L.4
Moore, D.T.5
Collichio, F.6
-
10
-
-
73049085665
-
SIP1 mediates cell-fatedecisions between neuroectoderm and mesendoderm in humanpluripotent stem cells
-
Chng Z, Teo A, Pedersen RA, Vallier L. (2010). SIP1 mediates cell-fatedecisions between neuroectoderm and mesendoderm in humanpluripotent stem cells. Cell Stem Cell 6: 59-70.
-
Cell Stem Cell
, vol.6
, pp. 59-70
-
-
Chng, Z.1
Teo, A.2
Pedersen, R.A.3
Vallier, L.4
-
11
-
-
0034964418
-
The two-handed e box binding zinc fingerprotein SIP1 downregulates E-cadherin and induces invasion
-
Comijn J, Berx G, Vermassen P, Verschueren K, van Grunsven L,Bruyneel E et al. (2001). The two-handed E box binding zinc fingerprotein SIP1 downregulates E-cadherin and induces invasion. MolCell 7: 1267-1278.
-
(2001)
MolCell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
Van Grunsven Lbruyneel, E.5
-
12
-
-
2342471301
-
Akt interacts directly with Smad3 to regulate the sensitivityto TGF-beta induced apoptosis
-
Conery AR, Cao Y, Thompson EA, Townsend Jr. M, Ko TC, Luo K.(2004). Akt interacts directly with Smad3 to regulate the sensitivityto TGF-beta induced apoptosis. Nat Cell Biol 6: 366-372.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 366-372
-
-
Conery, A.R.1
Cao, Y.2
Thompson, E.A.3
Townsend Jr., M.4
Ko, T.C.5
Luo, K.6
-
13
-
-
46449128469
-
SMAD proteins controlDROSHA-mediated microRNA maturation
-
Davis BN, Hilyard AC, Lagna G, Hata A. (2008). SMAD proteins controlDROSHA-mediated microRNA maturation. Nature 454: 56-61.
-
(2008)
Nature
, vol.454
, pp. 56-61
-
-
Davis, B.N.1
Hilyard, A.C.2
Lagna, G.3
Hata, A.4
-
14
-
-
77953663505
-
Antibodiestargeting cancer stem cells: A new paradigm in immunotherapy?
-
Deonarain MP, Kousparou CA, Epenetos AA. (2009). Antibodiestargeting cancer stem cells: a new paradigm in immunotherapy?MAbs 1: 12-25.
-
(2009)
MAbs
, vol.1
, pp. 12-25
-
-
Deonarain, M.P.1
Kousparou, C.A.2
Epenetos, A.A.3
-
15
-
-
0034785348
-
TGF-beta signaling intumor suppression and cancer progression
-
Derynck R, Akhurst RJ, Balmain A. (2001). TGF-beta signaling intumor suppression and cancer progression. Nat Genet 29: 117-129.
-
(2001)
Nat Genet
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
16
-
-
58549108859
-
The role of PTEN/Akt/PI3K signaling inthe maintenance and viability of prostate cancer stem-like cellpopulations
-
Dubrovska A, Kim S, Salamone RJ, Walker Jr., Maira SM, Garcia-Echeverria C et al. (2009). The role of PTEN/Akt/PI3K signaling inthe maintenance and viability of prostate cancer stem-like cellpopulations. Proc Natl Acad Sci USA 106: 268-273.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 268-273
-
-
Dubrovska, A.1
Kim, S.2
Salamone, R.J.3
Walker, J.4
Maira, S.M.5
Garcia-Echeverria, C.6
-
17
-
-
0022891340
-
Tumors: Wounds that do not heal. Similaritiesbetween tumor stroma generation and wound healing
-
Dvorak HF. (1986). Tumors: wounds that do not heal. Similaritiesbetween tumor stroma generation and wound healing. N EnglJ Med 315: 1650-1659.
-
(1986)
N Engl J Med
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
18
-
-
34249075147
-
MET amplification leads to gefitinib resistance inlung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, ParkJO et al. (2007). MET amplification leads to gefitinib resistance inlung cancer by activating ERBB3 signaling. Science 316: 1039-1043.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Parkjo, H.C.5
-
19
-
-
0035877989
-
Hoechst 33342 efflux identifiesa subpopulation of cytogenetically normal CD34(\+)CD38(-)progenitor cells from patients with acute myeloid leukemia
-
Feuring-Buske M, Hogge DE. (2001). Hoechst 33342 efflux identifiesa subpopulation of cytogenetically normal CD34(\+)CD38(-)progenitor cells from patients with acute myeloid leukemia. Blood97: 3882-3889.
-
(2001)
Blood
, vol.97
, pp. 3882-3889
-
-
Feuring-Buske, M.1
De, H.2
-
20
-
-
39749157093
-
Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT andinhibition of growth arrest and apoptosis
-
Gal A, Sjoblom T, Fedorova L, Imreh S, Beug H, Moustakas A.(2008). Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT andinhibition of growth arrest and apoptosis. Oncogene 27: 1218-1230.
-
(2008)
Oncogene
, vol.27
, pp. 1218-1230
-
-
Gal, A.1
Sjoblom, T.2
Fedorova, L.3
Imreh, S.4
Beug, H.5
Moustakas, A.6
-
21
-
-
70349142665
-
Contextual extracellular cues promote tumor cellEMT and metastasis by regulating miR-200 family expression
-
Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, GoodallGJ et al. (2009). Contextual extracellular cues promote tumor cellEMT and metastasis by regulating miR-200 family expression.Genes Dev 23: 2140-2151.
-
(2009)
Genes Dev
, vol.23
, pp. 2140-2151
-
-
Gibbons, D.L.1
Lin, W.2
Creighton, C.J.3
Zh, R.4
Goodallgj, G.P.5
-
22
-
-
35848955428
-
ALDH1 is a marker of normal andmalignant human mammary stem cells and a predictor of poorclinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J,Brown M et al. (2007). ALDH1 is a marker of normal andmalignant human mammary stem cells and a predictor of poorclinical outcome. Cell Stem Cell 1: 555-567.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
Monville, F.4
Dutcher Jbrown, M.5
-
23
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial tomesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid Get al. (2008). The miR-200 family and miR-205 regulate epithelial tomesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol10: 593-601.
-
(2008)
Nat Cell Biol10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
Barry, S.C.4
Tsykin, A.5
Farshid, G.6
-
25
-
-
68749099671
-
Identification of selective inhibitors of cancer stemcells by high-throughput screening
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RAet al. (2009b). Identification of selective inhibitors of cancer stemcells by high-throughput screening. Cell 138: 645-659.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
-
26
-
-
39449135834
-
PI3K pathway regulatessurvival of cancer stem cells residing in the perivascular niche followingradiation in medulloblastoma in vivo
-
Hambardzumyan D, Becher OJ, Rosenblum MK, Pandolfi PP,Manova-Todorova K, Holland EC. (2008). PI3K pathway regulatessurvival of cancer stem cells residing in the perivascular niche followingradiation in medulloblastoma in vivo. Genes Dev 22: 436-448.
-
(2008)
Genes Dev
, vol.22
, pp. 436-448
-
-
Hambardzumyan, D.1
Becher, O.J.2
Rosenblum, M.K.3
Pandolfi, P.P.4
Manova-Todorova, K.5
Holland, E.C.6
-
27
-
-
20444467290
-
A microRNA polycistron as a potentialhuman oncogene
-
He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D,Goodson S et al. (2005). A microRNA polycistron as a potentialhuman oncogene. Nature 435: 828-833.
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
Hernando-Monge, E.4
Mu Dgoodson, S.5
-
28
-
-
63749105896
-
Mechanism of TGFbetasignaling to growth arrest, apoptosis, and epithelial-mesenchymaltransition
-
Heldin CH, Landstrom M, Moustakas A. (2009). Mechanism of TGFbetasignaling to growth arrest, apoptosis, and epithelial- mesenchymaltransition. Curr Opin Cell Biol 21: 166-176.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 166-176
-
-
Heldin, C.H.1
Landstrom, M.2
Moustakas, A.3
-
29
-
-
34548455927
-
Distinct populations of cancer stem cells determinetumor growth and metastatic activity in human pancreatic cancer
-
Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba Met al. (2007). Distinct populations of cancer stem cells determinetumor growth and metastatic activity in human pancreatic cancer.Cell Stem Cell 1: 313-323.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
Aicher, A.4
Ellwart, J.W.5
Guba, M.6
-
30
-
-
70350236538
-
Metforminselectively targets cancer stem cells, and acts together withchemotherapy to block tumor growth and prolong remission
-
Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. (2009). Metforminselectively targets cancer stem cells, and acts together withchemotherapy to block tumor growth and prolong remission.Cancer Res 69: 7507-7511.
-
(2009)
Cancer Res
, vol.69
, pp. 7507-7511
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Tsichlis, P.N.3
Struhl, K.4
-
31
-
-
24644480749
-
Molecular requirements forepithelial-mesenchymal transition during tumor progression
-
Huber MA, Kraut N, Beug H. (2005). Molecular requirements forepithelial-mesenchymal transition during tumor progression. CurrOpin Cell Biol 17: 548-558.
-
(2005)
CurrOpin Cell Biol
, vol.17
, pp. 548-558
-
-
Huber, M.A.1
Kraut, N.2
Beug, H.3
-
32
-
-
18744375998
-
Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation
-
Jeong JW, Bae MK, Ahn MY, Kim SH, Sohn TK, Bae MH et al.(2002). Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell 111: 709-720.
-
(2002)
Cell
, vol.111
, pp. 709-720
-
-
Jeong, J.W.1
Bae, M.K.2
Ahn, M.Y.3
Kim, S.H.4
Sohn, T.K.5
Bae, M.H.6
-
33
-
-
67650085171
-
TGF-beta activates Akt kinase through a microRNA-dependentamplifying circuit targeting PTEN
-
Kato M, Putta S, Wang M, Yuan H, Lanting L, Nair I et al. (2009).TGF-beta activates Akt kinase through a microRNA-dependentamplifying circuit targeting PTEN. Nat Cell Biol 11: 881-889.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 881-889
-
-
Kato, M.1
Putta, S.2
Wang, M.3
Yuan, H.4
Lanting, L.5
Nair, I.6
-
34
-
-
51849097348
-
The role of PTEN signaling perturbationsin cancer and in targeted therapy
-
Keniry M, Parsons R. (2008). The role of PTEN signaling perturbationsin cancer and in targeted therapy. Oncogene 27: 5477-5485.
-
(2008)
Oncogene
, vol.27
, pp. 5477-5485
-
-
Keniry, M.1
Parsons, R.2
-
35
-
-
55849123946
-
MicroRNA-155 is regulated by the transforming growthfactor beta/Smad pathway and contributes to epithelial cellplasticity by targeting RhoA
-
Kong W, Yang H, He L, Zhao JJ, Coppola D, Dalton WS et al.(2008). MicroRNA-155 is regulated by the transforming growthfactor beta/Smad pathway and contributes to epithelial cellplasticity by targeting RhoA. Mol Cell Biol 28: 6773-6784.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6773-6784
-
-
Kong, W.1
Yang, H.2
He, L.3
Zhao, J.J.4
Coppola, D.5
Dalton, W.S.6
-
36
-
-
33644780111
-
Histonedeacetylase inhibitors induce VHL and ubiquitin- independentproteasomal degradation of hypoxia-inducible factor 1alpha
-
Kong X, Lin Z, Liang D, Fath D, Sang N, Caro J. (2006). Histonedeacetylase inhibitors induce VHL and ubiquitin-independentproteasomal degradation of hypoxia-inducible factor 1alpha. MolCell Biol 26: 2019-2028.
-
(2006)
MolCell Biol
, vol.26
, pp. 2019-2028
-
-
Kong, X.1
Lin, Z.2
Liang, D.3
Fath, D.4
Sang, N.5
Caro, J.6
-
37
-
-
47249091921
-
The miR-200 familyinhibits epithelial-mesenchymal transition and cancer cell migrationby direct targeting of E-cadherin transcriptional repressors ZEB1and ZEB2
-
Korpal M, Lee ES, Hu G, Kang Y. (2008). The miR-200 familyinhibits epithelial-mesenchymal transition and cancer cell migrationby direct targeting of E-cadherin transcriptional repressors ZEB1and ZEB2. J Biol Chem 283: 14910-14914.
-
(2008)
J Biol Chem
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
Kang, Y.4
-
38
-
-
66449136951
-
Therapeutic microRNA deliverysuppresses tumorigenesis in a murine liver cancer model
-
Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, MontgomeryCL, Hwang HW et al. (2009). Therapeutic microRNA deliverysuppresses tumorigenesis in a murine liver cancer model. Cell 137:1005-1017.
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomerycl, H.5
Wang, H.W.6
-
39
-
-
33746498580
-
Transformation from committed progenitor to leukaemiastem cell initiated by MLL-AF9
-
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J et al.(2006). Transformation from committed progenitor to leukaemiastem cell initiated by MLL-AF9. Nature 442: 818-822.
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
Stubbs, M.C.4
Wang, Y.5
Faber, J.6
-
40
-
-
64349122714
-
Potent and selective inhibitors of breast cancerresistance protein (ABCG2) derived from the p-glycoprotein(ABCB1) modulator tariquidar
-
Kuhnle M, Egger M, Muller C, Mahringer A, Bernhardt G, Fricker Get al. (2009). Potent and selective inhibitors of breast cancerresistance protein (ABCG2) derived from the p-glycoprotein(ABCB1) modulator tariquidar. J Med Chem 52: 1190-1197.
-
(2009)
J Med Chem
, vol.52
, pp. 1190-1197
-
-
Kuhnle, M.1
Egger, M.2
Muller, C.3
Mahringer, A.4
Bernhardt, G.5
Fricker, G.6
-
41
-
-
23944522749
-
Microarray analysis ofgene expression during epithelial-mesenchymal transformation
-
LaGamba D, Nawshad A, Hay ED. (2005). Microarray analysis ofgene expression during epithelial-mesenchymal transformation. DevDyn 234: 132-142.
-
(2005)
DevDyn
, vol.234
, pp. 132-142
-
-
La Gamba, D.1
Nawshad, A.2
Hay, E.D.3
-
42
-
-
73949128107
-
Histone deacetylase inhibitors incancer therapy
-
Lane AA, Chabner BA. (2009). Histone deacetylase inhibitors incancer therapy. J Clin Oncol 27: 5459-5468.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
-
43
-
-
0028091194
-
A cell initiating human acute myeloidleukaemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T,Caceres-Cortes J et al. (1994). A cell initiating human acute myeloidleukaemia after transplantation into SCID mice. Nature 367:645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
-
44
-
-
0016711859
-
Differentiation of erythroleukemiccells in the presence of inhibitors of DNA synthesis
-
Leder A, Orkin S, Leder P. (1975). Differentiation of erythroleukemiccells in the presence of inhibitors of DNA synthesis. Science 190:893-894.
-
(1975)
Science
, vol.190
, pp. 893-894
-
-
Leder, A.1
Orkin, S.2
Leder, P.3
-
45
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
Li H, Collado M, Villasante A, Strati K, Ortega S, Canamero M et al.(2009a). The Ink4/Arf locus is a barrier for iPS cell reprogramming.Nature 460: 1136-1139.
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
Collado, M.2
Villasante, A.3
Strati, K.4
Ortega, S.5
Canamero, M.6
-
46
-
-
44049100934
-
Intrinsic resistance of tumorigenic breast cancer cells tochemotherapy
-
Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF et al.(2008). Intrinsic resistance of tumorigenic breast cancer cells tochemotherapy. J Natl Cancer Inst 100: 672-679.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 672-679
-
-
Li, X.1
Lewis, M.T.2
Huang, J.3
Gutierrez, C.4
Osborne, C.K.5
Wu, M.F.6
-
47
-
-
69249096109
-
Up-regulation of miR-200 and let-7 by natural agents leadsto the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells
-
Li Y, VandenBoom II TG, Kong D, Wang Z, Ali S, Philip PA et al.(2009b). Up-regulation of miR-200 and let-7 by natural agents leadsto the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Cancer Res 69: 6704-6712.
-
(2009)
Cancer Res
, vol.69
, pp. 6704-6712
-
-
Li, Y.1
Vandenboom, I.I.T.G.2
Kong, D.3
Wang, Z.4
Ali, S.5
Philip, P.A.6
-
48
-
-
41649102048
-
Response to neoadjuvant therapy and long-term survivalin patients with triple-negative breast cancer
-
Liedtke C, Mazouni C, Hess KR, Andre F, Tordai A, Mejia JA et al.(2008). Response to neoadjuvant therapy and long-term survivalin patients with triple-negative breast cancer. J Clin Oncol 26:1275-1281.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
Andre, F.4
Tordai, A.5
Mejia, J.A.6
-
49
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population forbasal tumor development in BRCA1 mutation carriers
-
Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH et al. (2009).Aberrant luminal progenitors as the candidate target population forbasal tumor development in BRCA1 mutation carriers. Nat Med 15:907-913.
-
(2009)
Nat Med
, vol.15
, pp. 907-913
-
-
Lim, E.1
Vaillant, F.2
Wu, D.3
Forrest, N.C.4
Pal, B.5
Hart, A.H.6
-
50
-
-
62949170893
-
Mouse fibroblasts lacking RB1 function form spheresand undergo reprogramming to a cancer stem cell phenotype
-
Liu Y, Clem B, Zuba-Surma EK, El-Naggar S, Telang S, Jenson ABet al. (2009). Mouse fibroblasts lacking RB1 function form spheresand undergo reprogramming to a cancer stem cell phenotype. CellStem Cell 4: 336-347.
-
(2009)
CellStem Cell
, vol.4
, pp. 336-347
-
-
Liu, Y.1
Clem, B.2
Zuba-Surma, E.K.3
El-Naggar, S.4
Telang, S.5
Jenson, A.B.6
-
51
-
-
34748900267
-
Transgenic over-expression of the microRNA miR-17-92 clusterpromotes proliferation and inhibits differentiation of lung epithelialprogenitor cells
-
Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL. (2007).Transgenic over-expression of the microRNA miR-17-92 clusterpromotes proliferation and inhibits differentiation of lung epithelialprogenitor cells. Dev Biol 310: 442-453.
-
(2007)
Dev Biol
, vol.310
, pp. 442-453
-
-
Lu, Y.1
Thomson, J.M.2
Wong, H.Y.3
Hammond, S.M.4
Hogan, B.L.5
-
52
-
-
41649089525
-
Cutaneous cancer stem cell maintenance is dependenton beta-catenin signalling
-
Malanchi I, Peinado H, Kassen D, Hussenet T, Metzger D, ChambonP et al. (2008). Cutaneous cancer stem cell maintenance is dependenton beta-catenin signalling. Nature 452: 650-653.
-
(2008)
Nature
, vol.452
, pp. 650-653
-
-
Malanchi, I.1
Peinado, H.2
Kassen, D.3
Hussenet, T.4
Chambonp, M.D.5
-
53
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells withproperties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY et al.(2008). The epithelial-mesenchymal transition generates cells withproperties of stem cells. Cell 133: 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
-
54
-
-
77955804088
-
2010 Progressive 3q amplification consistentlytargets SOX2 in preinvasive squamous lung cancer
-
(e-pub ahead of print 18 March)
-
McCaughan F, Pole JC, Bankier AT, Konfortov BA, Carroll B,Falzon M et al. (2010). Progressive 3q amplification consistentlytargets SOX2 in preinvasive squamous lung cancer. Am J RespirCrit Care Med (e-pub ahead of print 18 March 2010
-
(2010)
Am J RespirCrit Care Med
-
-
McCaughan, F.1
Pole, J.C.2
Bankier, A.T.3
Konfortov, B.A.4
Carroll, B.5
Falzon, M.6
-
55
-
-
5144226211
-
PTEN activation contributes to tumor inhibition bytrastuzumab, and loss of PTEN predicts trastuzumab resistance inpatients
-
Nagata Y, Lan KH, Zhou X, Tan M, Esteva FJ, Sahin AA et al.(2004). PTEN activation contributes to tumor inhibition bytrastuzumab, and loss of PTEN predicts trastuzumab resistance inpatients. Cancer Cell 6: 117-127.
-
(2004)
Cancer Cell
, vol.6
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
Tan, M.4
Esteva, F.J.5
Sahin, A.A.6
-
56
-
-
33845209913
-
A collection of breast cancer cell lines for the study offunctionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T et al.(2006). A collection of breast cancer cell lines for the study offunctionally distinct cancer subtypes. Cancer Cell 10: 515-527.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
-
57
-
-
33846100356
-
A human coloncancer cell capable of initiating tumour growth in immunodeficientmice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. (2007). A human coloncancer cell capable of initiating tumour growth in immunodeficientmice. Nature 445: 106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
58
-
-
33744814477
-
Geneexpression and benefit of chemotherapy in women with nodenegative,estrogen receptor-positive breast cancer
-
Paik S, Tang G, Shak S, Kim C, Baker J, Kim W et al. (2006). Geneexpression and benefit of chemotherapy in women with nodenegative,estrogen receptor-positive breast cancer. J Clin Oncol 24:3726-3734.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3726-3734
-
-
Paik, S.1
Tang, G.2
Shak, S.3
Kim, C.4
Baker, J.5
Kim, W.6
-
59
-
-
0345059767
-
Applying the principles ofstem-cell biology to cancer
-
Pardal R, Clarke MF, Morrison SJ. (2003). Applying the principles ofstem-cell biology to cancer. Nat Rev Cancer 3: 895-902.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 895-902
-
-
Pardal, R.1
Clarke, M.F.2
Morrison, S.J.3
-
60
-
-
41649091906
-
The miR-200family determines the epithelial phenotype of cancer cells bytargeting the E-cadherin repressors ZEB1 and ZEB2
-
Park SM, Gaur AB, Lengyel E, Peter ME. (2008). The miR-200family determines the epithelial phenotype of cancer cells bytargeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev22: 894-907.
-
(2008)
Genes Dev22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
61
-
-
45549097925
-
Cancer stem cells and the ontogenyof lung cancer
-
Peacock CD, Watkins DN. (2008). Cancer stem cells and the ontogenyof lung cancer. J Clin Oncol 26: 2883-2889.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2883-2889
-
-
Peacock, C.D.1
Watkins, D.N.2
-
62
-
-
34249289041
-
Snail, Zeb and bHLH factorsin tumour progression: An alliance against the epithelial phenotype?
-
Peinado H, Olmeda D, Cano A. (2007). Snail, Zeb and bHLH factorsin tumour progression: an alliance against the epithelial phenotype?Nat Rev Cancer 7: 415-428.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
63
-
-
39849095077
-
E2F1-regulated microRNAs impairTGFbeta-dependent cell-cycle arrest and apoptosis in gastriccancer
-
Petrocca F, Visone R, Onelli MR, Shah MH, Nicoloso MS, deMartino I et al. (2008). E2F1-regulated microRNAs impairTGFbeta-dependent cell-cycle arrest and apoptosis in gastriccancer. Cancer Cell 13: 272-286.
-
(2008)
Cancer Cell
, vol.13
, pp. 272-286
-
-
Petrocca, F.1
Visone, R.2
Onelli, M.R.3
Shah, M.H.4
Nicoloso, M.S.5
De Martino, I.6
-
64
-
-
63049123066
-
Transitions between epithelial andmesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA. (2009). Transitions between epithelial andmesenchymal states: acquisition of malignant and stem cell traits.Nat Rev Cancer 9: 265-273.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
65
-
-
0038324070
-
Regulation ofSmad signaling through a differential recruitment of coactivatorsand corepressors by ZEB proteins
-
Postigo AA, Depp JL, Taylor JJ, Kroll KL. (2003). Regulation ofSmad signaling through a differential recruitment of coactivatorsand corepressors by ZEB proteins. EMBO J 22: 2453-2462.
-
(2003)
EMBO J
, vol.22
, pp. 2453-2462
-
-
Postigo, A.A.1
Depp, J.L.2
Taylor, J.J.3
Kroll, K.L.4
-
66
-
-
57349143739
-
Efficient tumour formation by single humanmelanoma cells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM,Morrison SJ. (2008). Efficient tumour formation by single humanmelanoma cells. Nature 456: 593-598.
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
67
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulatesdevelopmental timing in Caenorhabditis elegans
-
Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC,Rougvie AE et al. (2000). The 21-nucleotide let-7 RNA regulatesdevelopmental timing in Caenorhabditis elegans. Nature 403:901-906.
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
Pasquinelli, A.E.4
Bettinger, J.C.5
Rougvie, A.E.6
-
68
-
-
2342647439
-
PKB/Aktmodulates TGF-beta signalling through a direct interaction withSmad3
-
Remy I, Montmarquette A, Michnick SW. (2004). PKB/Aktmodulates TGF-beta signalling through a direct interaction withSmad3. Nat Cell Biol 6: 358-365.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 358-365
-
-
Remy, I.1
Montmarquette, A.2
Michnick, S.W.3
-
69
-
-
33846095137
-
Identification and expansion of humancolon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M,Peschle C et al. (2007). Identification and expansion of humancolon-cancer-initiating cells. Nature 445: 111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
-
70
-
-
0017767153
-
N-Butyrate causes histone modification in HeLa and Friend erythroleukaemiacells
-
Riggs MG, Whittaker RG, Neumann Jr., Ingram VM. (1977). n-Butyrate causes histone modification in HeLa and Friend erythroleukaemiacells. Nature 268: 462-464.
-
(1977)
Nature
, vol.268
, pp. 462-464
-
-
Riggs, M.G.1
Whittaker, R.G.2
Neumann, J.3
Ingram, V.M.4
-
71
-
-
34250761431
-
Inhibition of ABCG2-mediated transport byprotein kinase inhibitors with a bisindolylmaleimide or indolocarbazolestructure
-
Robey RW, Shukla S, Steadman K, Obrzut T, Finley EM, AmbudkarSV et al. (2007). Inhibition of ABCG2-mediated transport byprotein kinase inhibitors with a bisindolylmaleimide or indolocarbazolestructure. Mol Cancer Ther 6: 1877-1885.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1877-1885
-
-
Robey, R.W.1
Shukla, S.2
Steadman, K.3
Obrzut, T.4
Finley, E.M.5
Ambudkar, S.V.6
-
72
-
-
66149131111
-
Immune-induced epithelial to mesenchymaltransition in vivo generates breast cancer stem cells
-
Santisteban M, Reiman JM, Asiedu MK, Behrens MD, Nassar A,Kalli KR et al. (2009). Immune-induced epithelial to mesenchymaltransition in vivo generates breast cancer stem cells. Cancer Res 69:2887-2895.
-
(2009)
Cancer Res
, vol.69
, pp. 2887-2895
-
-
Santisteban, M.1
Reiman, J.M.2
Asiedu, M.K.3
Behrens, M.D.4
Nassar, A.5
Kalli, K.R.6
-
73
-
-
70349273757
-
SIP1 protein protects cells from DNA damage-inducedapoptosis and has independent prognostic value in bladder cancer
-
Sayan AE, Griffiths TR, Pal R, Browne GJ, Ruddick A, Yagci T et al.(2009). SIP1 protein protects cells from DNA damage-inducedapoptosis and has independent prognostic value in bladder cancer.Proc Natl Acad Sci USA 106: 14884-14889.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14884-14889
-
-
Sayan, A.E.1
Griffiths, T.R.2
Pal, R.3
Browne, G.J.4
Ruddick, A.5
Yagci, T.6
-
74
-
-
1642332084
-
Integration of Smad and forkhead pathways in the controlof neuroepithelial and glioblastoma cell proliferation
-
Seoane J, Le HV, Shen L, Anderson SA, Massague J. (2004).Integration of Smad and forkhead pathways in the controlof neuroepithelial and glioblastoma cell proliferation. Cell 117:211-223.
-
(2004)
Cell
, vol.117
, pp. 211-223
-
-
Seoane, J.1
Le Shen, H.V.L.2
Anderson, S.A.3
Massague, J.4
-
76
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state incancer cell subpopulations
-
Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran Set al. (2010). A chromatin-mediated reversible drug-tolerant state incancer cell subpopulations. Cell 141: 69-80.
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
Maheswaran, S.6
-
77
-
-
33847419142
-
Molecular definition of breast tumorheterogeneity
-
Shipitsin M, Campbell LL, Argani P, Weremowicz S, Bloushtain-Qimron N, Yao J et al. (2007). Molecular definition of breast tumorheterogeneity. Cancer Cell 11: 259-273.
-
(2007)
Cancer Cell
, vol.11
, pp. 259-273
-
-
Shipitsin, M.1
Campbell, L.L.2
Argani, P.3
Weremowicz, S.4
Bloushtain-Qimron, N.5
Yao, J.6
-
78
-
-
65649108558
-
A gene expression signature associated with 'K-Rasaddiction' reveals regulators of EMT and tumor cell survival
-
Singh A, Greninger P, Rhodes D, Koopman L, Violette S, Bardeesy Net al. (2009). A gene expression signature associated with 'K-Rasaddiction' reveals regulators of EMT and tumor cell survival.Cancer Cell 15: 489-500.
-
(2009)
Cancer Cell
, vol.15
, pp. 489-500
-
-
Singh, A.1
Greninger, P.2
Rhodes, D.3
Koopman, L.4
Violette, S.5
Bardeesy, N.6
-
79
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T et al.(2004). Identification of human brain tumour initiating cells. Nature432: 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
-
80
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguishtumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H et al.(2001). Gene expression patterns of breast carcinomas distinguishtumor subclasses with clinical implications. Proc Natl Acad Sci USA98: 10869-10874.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
Aas, T.4
Geisler, S.5
Johnsen, H.6
-
81
-
-
33747195353
-
Induction of pluripotent stem cellsfrom mouse embryonic and adult fibroblast cultures by definedfactors
-
Takahashi K, Yamanaka S. (2006). Induction of pluripotent stem cellsfrom mouse embryonic and adult fibroblast cultures by definedfactors. Cell 126: 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
82
-
-
0344845003
-
Epithelial-mesenchymal transitions in developmentand pathologies
-
Thiery JP. (2003). Epithelial-mesenchymal transitions in developmentand pathologies. Curr Opin Cell Biol 15: 740-746.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 740-746
-
-
Thiery, J.P.1
-
83
-
-
70450198396
-
Epithelialmesenchymaltransitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. (2009). Epithelialmesenchymaltransitions in development and disease. Cell 139:871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
84
-
-
33746034613
-
Transforming growth factor-beta employsHMGA2 to elicit epithelial-mesenchymal transition
-
Thuault S, Valcourt U, Petersen M, Manfioletti G, Heldin CH,Moustakas A. (2006). Transforming growth factor-beta employsHMGA2 to elicit epithelial-mesenchymal transition. J Cell Biol 174:175-183.
-
(2006)
J Cell Biol
, vol.174
, pp. 175-183
-
-
Thuault, S.1
Valcourt, U.2
Petersen, M.3
Manfioletti, G.4
Heldin, C.H.5
Moustakas, A.6
-
85
-
-
69349098273
-
Immortalization eliminates a roadblock during cellularreprogramming into iPS cells
-
Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, Walsh RMet al. (2009). Immortalization eliminates a roadblock during cellularreprogramming into iPS cells. Nature 460: 1145-1148.
-
(2009)
Nature
, vol.460
, pp. 1145-1148
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
Maherali, N.4
Kulalert, W.5
Walsh, R.M.6
-
86
-
-
0033575194
-
SIP1, a novel zinc finger/homeodomainrepressor, interacts with Smad proteins and binds to 50-CACCTsequences in candidate target genes
-
Verschueren K, Remacle JE, Collart C, Kraft H, Baker BS,Tylzanowski P et al. (1999). SIP1, a novel zinc finger/homeodomainrepressor, interacts with Smad proteins and binds to 50-CACCTsequences in candidate target genes. J Biol Chem 274: 20489-20498.
-
(1999)
J Biol Chem
, vol.274
, pp. 20489-20498
-
-
Verschueren, K.1
Remacle, J.E.2
Collart, C.3
Kraft, H.4
Baker, B.5
Stylzanowski, P.6
-
87
-
-
70349165716
-
Epithelial-mesenchymal transition incancer metastasis: Mechanisms, markers and strategies to overcomedrug resistance in the clinic
-
Voulgari A, Pintzas A. (2009). Epithelial-mesenchymal transition incancer metastasis: mechanisms, markers and strategies to overcomedrug resistance in the clinic. Biochim Biophys Acta 1796: 75-90.
-
(2009)
Biochim Biophys Acta
, vol.1796
, pp. 75-90
-
-
Voulgari, A.1
Pintzas, A.2
-
88
-
-
51349164414
-
Transforming growth factor beta engages TACE and ErbB3to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressingbreast cancer and desensitizes cells to trastuzumab
-
Wang SE, Xiang B, Guix M, Olivares MG, Parker J, Chung CH et al.(2008). Transforming growth factor beta engages TACE and ErbB3to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressingbreast cancer and desensitizes cells to trastuzumab. Mol CellBiol 28: 5605-5620.
-
(2008)
Mol CellBiol
, vol.28
, pp. 5605-5620
-
-
Wang, S.E.1
Xiang, B.2
Guix, M.3
Olivares, M.G.4
Parker, J.5
Chung, C.H.6
-
89
-
-
73049110243
-
The EMT-activator ZEB1 promotes tumorigenicityby repressing stemness-inhibiting microRNAs
-
Wellner U, Schubert J, Burk UC, Schmalhofer O, Zhu F, Sonntag Aet al. (2009). The EMT-activator ZEB1 promotes tumorigenicityby repressing stemness-inhibiting microRNAs. Nat Cell Biol 11:1487-1495.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1487-1495
-
-
Wellner, U.1
Schubert, J.2
Burk, U.C.3
Schmalhofer, O.4
Zhu, F.5
Sonntag, A.6
-
90
-
-
75649088874
-
Mechanisms of theepithelial-mesenchymal transition by TGF-beta
-
Wendt MK, Allington TM, Schiemann WP. (2009). Mechanisms of theepithelial-mesenchymal transition by TGF-beta. Future Oncol 5:1145-1168.
-
(2009)
Future Oncol
, vol.5
, pp. 1145-1168
-
-
Wendt, M.K.1
Allington, T.M.2
Schiemann, W.P.3
-
91
-
-
0032912720
-
Expression of CD44 in Apc and Tcf mutant mice impliesregulation by the WNT pathway
-
Wielenga VJ, Smits R, Korinek V, Smit L, Kielman M, Fodde R et al.(1999). Expression of CD44 in Apc and Tcf mutant mice impliesregulation by the WNT pathway. Am J Pathol 154: 515-523.
-
(1999)
Am J Pathol
, vol.154
, pp. 515-523
-
-
Wielenga, V.J.1
Smits, R.2
Korinek, V.3
Smit, L.4
Kielman, M.5
Fodde, R.6
-
92
-
-
31544452076
-
Restoring E-cadherin expression increases sensitivityto epidermal growth factor receptor inhibitors in lung cancer celllines
-
Witta SE, Gemmill RM, Hirsch FR, Coldren CD, Hedman K, RavdelL et al. (2006). Restoring E-cadherin expression increases sensitivityto epidermal growth factor receptor inhibitors in lung cancer celllines. Cancer Res 66: 944-950.
-
(2006)
Cancer Res
, vol.66
, pp. 944-950
-
-
Witta, S.E.1
Gemmill, R.M.2
Hirsch, F.R.3
Coldren, C.D.4
Ravdell, H.K.5
-
93
-
-
60449087921
-
EpCAM-positive hepatocellular carcinoma cells are tumorinitiatingcells with stem/progenitor cell features
-
Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY et al.(2009). EpCAM-positive hepatocellular carcinoma cells are tumorinitiatingcells with stem/progenitor cell features. Gastroenterology136: 1012-1024.
-
(2009)
Gastroenterology
, vol.136
, pp. 1012-1024
-
-
Yamashita, T.1
Ji, J.2
Budhu, A.3
Forgues, M.4
Yang, W.5
Wang, H.Y.6
-
94
-
-
44449144396
-
Epithelial-mesenchymal transition:at the crossroads of development and tumor metastasis
-
Yang J, Weinberg RA. (2008). Epithelial-mesenchymal transition:at the crossroads of development and tumor metastasis. Dev Cell 14:818-829.
-
(2008)
Dev Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
95
-
-
29344465338
-
Epithelial versus mesenchymal phenotype determines in vitrosensitivity and predicts clinical activity of erlotinib in lung cancerpatients
-
Yauch RL, Januario T, Eberhard DA, Cavet G, Zhu W, Fu L et al.(2005). Epithelial versus mesenchymal phenotype determines in vitrosensitivity and predicts clinical activity of erlotinib in lung cancerpatients. Clin Cancer Res 11: 8686-8698.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8686-8698
-
-
Yauch, R.L.1
Januario, T.2
Eberhard, D.A.3
Cavet, G.4
Zhu, W.5
Fu, L.6
-
96
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stemcells from leukaemia-initiating cells
-
Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, Wu Het al. (2006). Pten dependence distinguishes haematopoietic stemcells from leukaemia-initiating cells. Nature 441: 475-482.
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
-
97
-
-
36849078711
-
Let-7regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C et al. (2007a). let-7regulates self renewal and tumorigenicity of breast cancer cells. Cell131: 1109-1123.
-
(2007)
Cell131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
Gong, C.6
-
98
-
-
36749043230
-
Induced pluripotent stem cell lines derivedfrom human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, FraneJL, Tian S et al. (2007b). Induced pluripotent stem cell lines derivedfrom human somatic cells. Science 318: 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Franejl5
Tian, S.6
-
99
-
-
77949360656
-
Sex determining region Y-Box 2 (SOX2) is a potential celllineagegene highly expressed in the pathogenesis of squamous cellcarcinomas of the lung
-
Yuan P, Kadara H, Behrens C, Tang X, Woods D, Solis LM et al.(2010). Sex determining region Y-Box 2 (SOX2) is a potential celllineagegene highly expressed in the pathogenesis of squamous cellcarcinomas of the lung. PLoS One 5: e9112.
-
(2010)
PLoS One
, vol.5
-
-
Yuan, P.1
Kadara, H.2
Behrens, C.3
Tang, X.4
Woods, D.5
Solis, L.M.6
-
100
-
-
67650996754
-
Biomarkers for epithelial-mesenchymaltransitions
-
Zeisberg M, Neilson EG. (2009). Biomarkers for epithelial- mesenchymaltransitions. J Clin Invest 119: 1429-1437.
-
(2009)
J Clin Invest
, vol.119
, pp. 1429-1437
-
-
Zeisberg, M.1
Neilson, E.G.2
-
101
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities foranticancer drug discovery
-
Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB.(2009). Tumour-initiating cells: challenges and opportunities foranticancer drug discovery. Nat Rev Drug Discov 8: 806-823.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 806-823
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
102
-
-
36048963331
-
Activation of the PTEN/mTOR/STAT3 pathway in breast cancerstem-like cells is required for viability and maintenance
-
Zhou J, Wulfkuhle J, Zhang H, Gu P, Yang Y, Deng J et al. (2007).Activation of the PTEN/mTOR/STAT3 pathway in breast cancerstem-like cells is required for viability and maintenance. Proc NatlAcad Sci USA 104: 16158-16163.
-
(2007)
Proc NatlAcad Sci USA
, vol.104
, pp. 16158-16163
-
-
Zhou, J.1
Wulfkuhle, J.2
Zhang, H.3
Gu, P.4
Yang, Y.5
Deng, J.6
|