NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Banskota, Suhrid ^a   Regmi, Sushil C ^a   Kim, Jung Ae ^a  

^a Yeungnam University   (South Korea)

Author keywords

AMPK; Colon cancer; Invasive phenotype; MMP 7; NOX1; NOX2

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MATRILYSIN; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; CYBB PROTEIN, HUMAN; MEMBRANE PROTEIN; NOX1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ARTICLE; AUTOREGULATION; CACO 2 CELL LINE; CANCER CELL; CELL INVASION; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HT 29 CELL LINE; HUMAN; HUMAN CELL; NOX2 GENE; PHENOTYPE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; ROS GENE; WESTERN BLOTTING; CELL MOTION; COLON TUMOR; GENETICS; HT-29 CELL LINE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; GENE EXPRESSION; HT29 CELLS; HUMANS; MATRIX METALLOPROTEINASE 7; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; PHENOTYPE; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84934277211     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0379-0     Document Type: Article

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