메뉴 건너뛰기




Volumn 311, Issue 2, 2016, Pages L433-L452

Differential regulation of autophagy and mitophagy in pulmonary diseases

Author keywords

ALI; COPD; IPF; PAH; PH

Indexed keywords

ACUTE LUNG INJURY; AUTOPHAGY; CHRONIC OBSTRUCTIVE LUNG DISEASE; HUMAN; LUNG DISEASE; LUNG FIBROSIS; MITOCHONDRION; MITOPHAGY; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REGULATORY MECHANISM; REVIEW; ANIMAL; LYSOSOME; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

EID: 84983740505     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00128.2016     Document Type: Review
Times cited : (111)

References (127)
  • 2
    • 84940404091 scopus 로고    scopus 로고
    • Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: Implications for chronic obstructive pulmonary disease
    • Ahmad T, Sundar IK, Lerner CA, Gerloff J, Tormos AM, Yao H, Rahman I. Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. FASEB J 29: 2912-2929, 2015.
    • (2015) FASEB J , vol.29 , pp. 2912-2929
    • Ahmad, T.1    Sundar, I.K.2    Lerner, C.A.3    Gerloff, J.4    Tormos, A.M.5    Yao, H.6    Rahman, I.7
  • 9
    • 33845480131 scopus 로고    scopus 로고
    • Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
    • Bernales S, McDonald KL, Walter P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol 4: e423, 2006.
    • (2006) Plos Biol , vol.4
    • Bernales, S.1    McDonald, K.L.2    Walter, P.3
  • 10
    • 79958198426 scopus 로고    scopus 로고
    • Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury
    • Bodas M, Min T, Vij N. Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury. Am J Physiol Lung Cell Mol Physiol 300: L811-L820, 2011.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.300 , pp. L811-L820
    • Bodas, M.1    Min, T.2    Vij, N.3
  • 12
    • 84917743297 scopus 로고    scopus 로고
    • Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis
    • Chang AL, Ulrich A, Suliman HB, Piantadosi CA. Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis. Free Radic Biol Med 78: 179-189, 2015.
    • (2015) Free Radic Biol Med , vol.78 , pp. 179-189
    • Chang, A.L.1    Ulrich, A.2    Suliman, H.B.3    Piantadosi, C.A.4
  • 13
    • 84940205052 scopus 로고    scopus 로고
    • Association of Egr-1 and autophagy-related gene polymorphism in men with chronic obstructive pulmonary disease
    • Chen CZ, Ou CY, Wang RH, Lee CH, Lin CC, Chang HY, Hsiue TR. Association of Egr-1 and autophagy-related gene polymorphism in men with chronic obstructive pulmonary disease. J Formos Med Assoc 114: 750-755, 2015.
    • (2015) J Formos Med Assoc , vol.114 , pp. 750-755
    • Chen, C.Z.1    Ou, C.Y.2    Wang, R.H.3    Lee, C.H.4    Lin, C.C.5    Chang, H.Y.6    Hsiue, T.R.7
  • 15
  • 16
    • 84942295210 scopus 로고    scopus 로고
    • Berberine inhibits Smad and non-Smad signaling cascades and enhances autophagy against pulmonary fibrosis
    • Chitra P, Saiprasad G, Manikandan R, Sudhandiran G. Berberine inhibits Smad and non-Smad signaling cascades and enhances autophagy against pulmonary fibrosis. J Mol Med 93: 1015-1031, 2015.
    • (2015) J Mol Med , vol.93 , pp. 1015-1031
    • Chitra, P.1    Saiprasad, G.2    Manikandan, R.3    Sudhandiran, G.4
  • 17
    • 84877609568 scopus 로고    scopus 로고
    • Autophagy in human health and disease
    • Choi AM, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med 368: 1845-1846, 2013.
    • (2013) N Engl J Med , vol.368 , pp. 1845-1846
    • Choi, A.M.1    Ryter, S.W.2    Levine, B.3
  • 20
    • 84919643533 scopus 로고    scopus 로고
    • A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy
    • Deegan S, Koryga I, Glynn SA, Gupta S, Gorman AM, Samali A. A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy. Biochem Biophys Res Commun 456: 305-311, 2015.
    • (2015) Biochem Biophys Res Commun , vol.456 , pp. 305-311
    • Deegan, S.1    Koryga, I.2    Glynn, S.A.3    Gupta, S.4    Gorman, A.M.5    Samali, A.6
  • 21
    • 84879607395 scopus 로고    scopus 로고
    • Stress-induced selfcannibalism: On the regulation of autophagy by endoplasmic reticulum stress
    • Deegan S, Saveljeva S, Gorman AM, Samali A. Stress-induced selfcannibalism: on the regulation of autophagy by endoplasmic reticulum stress. Cell Mol Life Sci 70: 2425-2441, 2013.
    • (2013) Cell Mol Life Sci , vol.70 , pp. 2425-2441
    • Deegan, S.1    Saveljeva, S.2    Gorman, A.M.3    Samali, A.4
  • 23
    • 84879047011 scopus 로고    scopus 로고
    • Cellular metabolic and autophagic pathways: Traffic control by redox signaling
    • Dodson M, Darley-Usmar V, Zhang J. Cellular metabolic and autophagic pathways: traffic control by redox signaling. Free Radic Biol Med 63: 207-221, 2013.
    • (2013) Free Radic Biol Med , vol.63 , pp. 207-221
    • Dodson, M.1    Darley-Usmar, V.2    Zhang, J.3
  • 24
    • 84938487642 scopus 로고    scopus 로고
    • KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity
    • Dodson M, Redmann M, Rajasekaran NS, Darley-Usmar V, Zhang J. KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity. Biochem J 469: 347-355, 2015.
    • (2015) Biochem J , vol.469 , pp. 347-355
    • Dodson, M.1    Redmann, M.2    Rajasekaran, N.S.3    Darley-Usmar, V.4    Zhang, J.5
  • 29
    • 84878772042 scopus 로고    scopus 로고
    • Oxidized lipids activate autophagy in a JNKdependent manner by stimulating the endoplasmic reticulum stress response
    • Haberzettl P, Hill BG. Oxidized lipids activate autophagy in a JNKdependent manner by stimulating the endoplasmic reticulum stress response. Redox Biol 1: 56-64, 2013.
    • (2013) Redox Biol , vol.1 , pp. 56-64
    • Haberzettl, P.1    Hill, B.G.2
  • 30
    • 84906880164 scopus 로고    scopus 로고
    • Reserve autophagic capacity in alveolar epithelia provides a replicative niche for influenza A virus
    • Hahn DR, Na CL, Weaver TE. Reserve autophagic capacity in alveolar epithelia provides a replicative niche for influenza A virus. Am J Respir Cell Mol Biol 51: 400-412, 2014.
    • (2014) Am J Respir Cell Mol Biol , vol.51 , pp. 400-412
    • Hahn, D.R.1    Na, C.L.2    Weaver, T.E.3
  • 35
    • 77951237303 scopus 로고    scopus 로고
    • The Beclin 1 interactome
    • He C, Levine B. The Beclin 1 interactome. Curr Opin Cell Biol 22: 140-149, 2010.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 140-149
    • He, C.1    Levine, B.2
  • 38
    • 84907169996 scopus 로고    scopus 로고
    • Elastase induces lung epithelial cell autophagy through placental growth factor: A new insight of emphysema pathogenesis
    • Hou HH, Cheng SL, Chung KP, Kuo MY, Yeh CC, Chang BE, Lu HH, Wang HC, Yu CJ. Elastase induces lung epithelial cell autophagy through placental growth factor: a new insight of emphysema pathogenesis. Autophagy 10: 1509-1521, 2014.
    • (2014) Autophagy , vol.10 , pp. 1509-1521
    • Hou, H.H.1    Cheng, S.L.2    Chung, K.P.3    Kuo, M.Y.4    Yeh, C.C.5    Chang, B.E.6    Lu, H.H.7    Wang, H.C.8    Yu, C.J.9
  • 39
    • 84905443837 scopus 로고    scopus 로고
    • Complement C5a exacerbates acute lung injury induced through autophagy-mediated alveolar macrophage apoptosis
    • Hu R, Chen ZF, Yan J, Li QF, Huang Y, Xu H, Zhang X, Jiang H. Complement C5a exacerbates acute lung injury induced through autophagy-mediated alveolar macrophage apoptosis. Cell Death Dis 5: e1330, 2014.
    • (2014) Cell Death Dis , vol.1330 , pp. 5
    • Hu, R.1    Chen, Z.F.2    Yan, J.3    Li, Q.F.4    Huang, Y.5    Xu, H.6    Zhang, X.7    Jiang, H.8
  • 40
    • 77954623119 scopus 로고    scopus 로고
    • Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: Implication in pathogenesis of COPD
    • Hwang JW, Chung S, Sundar IK, Yao H, Arunachalam G, McBurney MW, Rahman I. Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. Arch Biochem Biophys 500: 203-209, 2010.
    • (2010) Arch Biochem Biophys , vol.500 , pp. 203-209
    • Hwang, J.W.1    Chung, S.2    Sundar, I.K.3    Yao, H.4    Arunachalam, G.5    McBurney, M.W.6    Rahman, I.7
  • 41
    • 84941766194 scopus 로고    scopus 로고
    • Reduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices
    • Im J, Hergert P, Nho RS. Reduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices. Am J Physiol Lung Cell Mol Physiol 309: L552-L561, 2015.
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.309 , pp. L552-L561
    • Im, J.1    Hergert, P.2    Nho, R.S.3
  • 42
    • 78651282673 scopus 로고    scopus 로고
    • P62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
    • Itakura E, Mizushima N. p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J Cell Biol 192: 17-27, 2011.
    • (2011) J Cell Biol , vol.192 , pp. 17-27
    • Itakura, E.1    Mizushima, N.2
  • 46
    • 84875083992 scopus 로고    scopus 로고
    • SnapShot: Selective autophagy
    • Jin M, Liu X, Klionsky DJ. SnapShot: selective autophagy. Cell 152: 368, 2013.
    • (2013) Cell , vol.152 , pp. 368
    • Jin, M.1    Liu, X.2    Klionsky, D.J.3
  • 49
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R, Zeh HJ, Lotze MT, Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18: 571-580, 2011.
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 51
    • 53549090696 scopus 로고    scopus 로고
    • Autophagic proteins regulate cigarette smoke-induced apoptosis: Protective role of heme oxygenase-1
    • Kim HP, Wang X, Chen ZH, Lee SJ, Huang MH, Wang Y, Ryter SW, Choi AM. Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy 4: 887-895, 2008.
    • (2008) Autophagy , vol.4 , pp. 887-895
    • Kim, H.P.1    Wang, X.2    Chen, Z.H.3    Lee, S.J.4    Huang, M.H.5    Wang, Y.6    Ryter, S.W.7    Choi, A.M.8
  • 52
  • 57
    • 84960392538 scopus 로고    scopus 로고
    • Macrophage Akt1 kinase-mediated mitophagy modulates apoptosis resistance and pulmonary fibrosis
    • Larson-Casey JL, Deshane JS, Ryan AJ, Thannickal VJ, Carter AB. Macrophage Akt1 kinase-mediated mitophagy modulates apoptosis resistance and pulmonary fibrosis. Immunity 44: 582-596, 2016.
    • (2016) Immunity , vol.44 , pp. 582-596
    • Larson-Casey, J.L.1    Deshane, J.S.2    Ryan, A.J.3    Thannickal, V.J.4    Carter, A.B.5
  • 58
    • 84555195856 scopus 로고    scopus 로고
    • Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling
    • Lee J, Giordano S, Zhang J. Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem J 441: 523-540, 2012.
    • (2012) Biochem J , vol.441 , pp. 523-540
    • Lee, J.1    Giordano, S.2    Zhang, J.3
  • 62
    • 16844366524 scopus 로고    scopus 로고
    • Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging
    • Lemasters JJ. Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. Rejuvenation Res 8: 3-5, 2005.
    • (2005) Rejuvenation Res , vol.8 , pp. 3-5
    • Lemasters, J.J.1
  • 63
    • 84921529601 scopus 로고    scopus 로고
    • Atg7 enhances host defense against infection via downregulation of superoxide but upregulation of nitric oxide
    • Li X, Ye Y, Zhou X, Huang C, Wu M. Atg7 enhances host defense against infection via downregulation of superoxide but upregulation of nitric oxide. J Immunol 194: 1112-1121, 2015.
    • (2015) J Immunol , vol.194 , pp. 1112-1121
    • Li, X.1    Ye, Y.2    Zhou, X.3    Huang, C.4    Wu, M.5
  • 65
    • 84876287362 scopus 로고    scopus 로고
    • Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice
    • Lin CW, Zhang H, Li M, Xiong X, Chen X, Chen X, Dong XC, Yin XM. Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. J Hepatol 58: 993-999, 2013.
    • (2013) J Hepatol , vol.58 , pp. 993-999
    • Lin, C.W.1    Zhang, H.2    Li, M.3    Xiong, X.4    Chen, X.5    Chen, X.6    Dong, X.C.7    Yin, X.M.8
  • 66
    • 84889787284 scopus 로고    scopus 로고
    • Participation of autophagy in acute lung injury induced by seawater
    • Liu QP, Zhou DX, Lin P, Gao XL, Pan L, Jin FG. Participation of autophagy in acute lung injury induced by seawater. Exp Lung Res 39: 441-452, 2013.
    • (2013) Exp Lung Res , vol.39 , pp. 441-452
    • Liu, Q.P.1    Zhou, D.X.2    Lin, P.3    Gao, X.L.4    Pan, L.5    Jin, F.G.6
  • 67
    • 84872298070 scopus 로고    scopus 로고
    • Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice
    • Lo S, Yuan SS, Hsu C, Cheng YJ, Chang YF, Hsueh HW, Lee PH, Hsieh YC. Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice. Ann Surg 257: 352-363, 2013.
    • (2013) Ann Surg , vol.257 , pp. 352-363
    • Lo, S.1    Yuan, S.S.2    Hsu, C.3    Cheng, Y.J.4    Chang, Y.F.5    Hsueh, H.W.6    Lee, P.H.7    Hsieh, Y.C.8
  • 68
    • 84876367698 scopus 로고    scopus 로고
    • Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation
    • Long L, Yang X, Southwood M, Lu J, Marciniak SJ, Dunmore BJ, Morrell NW. Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation. Circ Res 112: 1159-1170, 2013.
    • (2013) Circ Res , vol.112 , pp. 1159-1170
    • Long, L.1    Yang, X.2    Southwood, M.3    Lu, J.4    Marciniak, S.J.5    Dunmore, B.J.6    Morrell, N.W.7
  • 71
    • 82455212854 scopus 로고    scopus 로고
    • Virus H5N1 causes autophagy-mediated cell death through suppression of mTOR signaling
    • Ma J, Sun Q, Mi R, Zhang H. Avian influenza A virus H5N1 causes autophagy-mediated cell death through suppression of mTOR signaling. J Genet Genomics 38: 533-537, 2011.
    • (2011) J Genet Genomics , vol.38 , pp. 533-537
    • Ma, J.1    Sun, Q.2    Mi, R.3    Zhang, H.4    Avian Influenza, A.5
  • 74
    • 80053070208 scopus 로고    scopus 로고
    • Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and-independent mechanisms
    • Mi S, Li Z, Yang HZ, Liu H, Wang JP, Ma YG, Wang XX, Liu HZ, Sun W, Hu ZW. Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and-independent mechanisms. J Immunol 187: 3003-3014, 2011.
    • (2011) J Immunol , vol.187 , pp. 3003-3014
    • Mi, S.1    Li, Z.2    Yang, H.Z.3    Liu, H.4    Wang, J.P.5    Ma, Y.G.6    Wang, X.X.7    Liu, H.Z.8    Sun, W.9    Hu, Z.W.10
  • 75
    • 84910648789 scopus 로고    scopus 로고
    • Emerging role of selective autophagy in human diseases
    • Mizumura K, Choi AM, Ryter SW. Emerging role of selective autophagy in human diseases. Front Pharmacol 5: 244, 2014.
    • (2014) Front Pharmacol , vol.5 , pp. 244
    • Mizumura, K.1    Choi, A.M.2    Ryter, S.W.3
  • 79
    • 84899639570 scopus 로고    scopus 로고
    • IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases
    • Nho RS, Hergert P. IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases. PLoS One 9: e94616, 2014.
    • (2014) Plos One , vol.9
    • Nho, R.S.1    Hergert, P.2
  • 81
    • 84892604558 scopus 로고    scopus 로고
    • Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-кB and p38 MAPK signaling pathways
    • Pan H, Zhang Y, Luo Z, Li P, Liu L, Wang C, Wang H, Li H, Ma Y. Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-кB and p38 MAPK signaling pathways. Am J Physiol Lung Cell Mol Physiol 306: L183-L195, 2014.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.306 , pp. L183-L195
    • Pan, H.1    Zhang, Y.2    Luo, Z.3    Li, P.4    Liu, L.5    Wang, C.6    Wang, H.7    Li, H.8    Ma, Y.9
  • 86
    • 84856456016 scopus 로고    scopus 로고
    • Autophagy mechanism of right ventricular remodeling in murine model of pulmonary artery constriction
    • Qipshidze N, Tyagi N, Metreveli N, Lominadze D, Tyagi SC. Autophagy mechanism of right ventricular remodeling in murine model of pulmonary artery constriction. Am J Physiol Heart Circ Physiol 302: H688-H696, 2012.
    • (2012) Am J Physiol Heart Circ Physiol , vol.302 , pp. H688-H696
    • Qipshidze, N.1    Tyagi, N.2    Metreveli, N.3    Lominadze, D.4    Tyagi, S.C.5
  • 87
    • 84924853843 scopus 로고    scopus 로고
    • YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress
    • Rainbolt TK, Saunders JM, Wiseman RL. YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress. EMBO Rep 16: 97-106, 2015.
    • (2015) EMBO Rep , vol.16 , pp. 97-106
    • Rainbolt, T.K.1    Saunders, J.M.2    Wiseman, R.L.3
  • 88
    • 42649146208 scopus 로고    scopus 로고
    • SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease
    • Rajendrasozhan S, Yang SR, Kinnula VL, Rahman I. SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 177: 861-870, 2008.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 861-870
    • Rajendrasozhan, S.1    Yang, S.R.2    Kinnula, V.L.3    Rahman, I.4
  • 90
    • 84922481952 scopus 로고    scopus 로고
    • Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure
    • Rawat DK, Alzoubi A, Gupte R, Chettimada S, Watanabe M, Kahn AG, Okada T, McMurtry IF, Gupte SA. Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure. Hypertension 64: 1266-1274, 2014.
    • (2014) Hypertension , vol.64 , pp. 1266-1274
    • Rawat, D.K.1    Alzoubi, A.2    Gupte, R.3    Chettimada, S.4    Watanabe, M.5    Kahn, A.G.6    Okada, T.7    McMurtry, I.F.8    Gupte, S.A.9
  • 93
    • 84891745585 scopus 로고    scopus 로고
    • Autophagy regulation by nutrient signaling
    • Russell RC, Yuan HX, Guan KL. Autophagy regulation by nutrient signaling. Cell Res 24: 42-57, 2014.
    • (2014) Cell Res , vol.24 , pp. 42-57
    • Russell, R.C.1    Yuan, H.X.2    Guan, K.L.3
  • 95
    • 84921469717 scopus 로고    scopus 로고
    • Autophagy in lung disease pathogenesis and therapeutics
    • Ryter SW, Choi AM. Autophagy in lung disease pathogenesis and therapeutics. Redox Biol 4: 215-225, 2015.
    • (2015) Redox Biol , vol.4 , pp. 215-225
    • Ryter, S.W.1    Choi, A.M.2
  • 97
    • 84863677794 scopus 로고    scopus 로고
    • Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy
    • Shi J, Yin N, Xuan LL, Yao CS, Meng AM, Hou Q. Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy. Acta Pharmacol Sin 33: 888-896, 2012.
    • (2012) Acta Pharmacol Sin , vol.33 , pp. 888-896
    • Shi, J.1    Yin, N.2    Xuan, L.L.3    Yao, C.S.4    Meng, A.M.5    Hou, Q.6
  • 99
    • 84940894774 scopus 로고    scopus 로고
    • Deregulation of selective autophagy during aging and pulmonary fibrosis: The role of TGFbeta1
    • Sosulski ML, Gongora R, Danchuk S, Dong C, Luo F, Sanchez CG. Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFbeta1. Aging Cell 14: 774-783, 2015.
    • (2015) Aging Cell , vol.14 , pp. 774-783
    • Sosulski, M.L.1    Gongora, R.2    Danchuk, S.3    Dong, C.4    Luo, F.5    Sanchez, C.G.6
  • 100
    • 71949129187 scopus 로고    scopus 로고
    • Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
    • Stenmark KR, Meyrick B, Galie N, Mooi WJ, McMurtry IF. Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol 297: L1013-L1032, 2009.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297 , pp. L1013-L1032
    • Stenmark, K.R.1    Meyrick, B.2    Galie, N.3    Mooi, W.J.4    McMurtry, I.F.5
  • 106
  • 107
    • 84859447737 scopus 로고    scopus 로고
    • Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension
    • Teng RJ, Du J, Welak S, Guan T, Eis A, Shi Y, Konduri GG. Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 302: L651-L663, 2012.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302 , pp. L651-L663
    • Teng, R.J.1    Du, J.2    Welak, S.3    Guan, T.4    Eis, A.5    Shi, Y.6    Konduri, G.G.7
  • 109
    • 84938935069 scopus 로고    scopus 로고
    • Role of cigarette smokeinduced aggresome formation in chronic obstructive pulmonary diseaseemphysema pathogenesis
    • Tran I, Ji C, Ni I, Min T, Tang D, Vij N. Role of cigarette smokeinduced aggresome formation in chronic obstructive pulmonary diseaseemphysema pathogenesis. Am J Respir Cell Mol Biol 53: 159-173, 2015.
    • (2015) Am J Respir Cell Mol Biol , vol.53 , pp. 159-173
    • Tran, I.1    Ji, C.2    Ni, I.3    Min, T.4    Tang, D.5    Vij, N.6
  • 110
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 15: 2922-2933, 2001.
    • (2001) Genes Dev , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 112
    • 84908124134 scopus 로고    scopus 로고
    • Neutrophils counteract autophagy-mediated anti-inflammatory mechanisms in alveolar macrophage: Role in posthemorrhagic shock acute lung inflammation
    • Wen Z, Fan L, Li Y, Zou Z, Scott MJ, Xiao G, Li S, Billiar TR, Wilson MA, Shi X, Fan J. Neutrophils counteract autophagy-mediated anti-inflammatory mechanisms in alveolar macrophage: role in posthemorrhagic shock acute lung inflammation. J Immunol 193: 4623-4633, 2014.
    • (2014) J Immunol , vol.193 , pp. 4623-4633
    • Wen, Z.1    Fan, L.2    Li, Y.3    Zou, Z.4    Scott, M.J.5    Xiao, G.6    Li, S.7    Billiar, T.R.8    Wilson, M.A.9    Shi, X.10    Fan, J.11
  • 114
    • 84960437624 scopus 로고    scopus 로고
    • Macrophages in tissue repair, regeneration, and fibrosis
    • Wynn TA, Vannella KM. Macrophages in tissue repair, regeneration, and fibrosis. Immunity 44: 450-462, 2016.
    • (2016) Immunity , vol.44 , pp. 450-462
    • Wynn, T.A.1    Vannella, K.M.2
  • 115
    • 84902285069 scopus 로고    scopus 로고
    • Vam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function
    • Xuan LL, Shi J, Yao CS, Bai JY, Qu F, Zhang JL, Hou Q. Vam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function. Acta Pharmacol Sin 35: 779-791, 2014.
    • (2014) Acta Pharmacol Sin , vol.35 , pp. 779-791
    • Xuan, L.L.1    Shi, J.2    Yao, C.S.3    Bai, J.Y.4    Qu, F.5    Zhang, J.L.6    Hou, Q.7
  • 116
    • 84906905024 scopus 로고    scopus 로고
    • Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice
    • Ye Y, Li X, Wang W, Ouedraogo KC, Li Y, Gan C, Tan S, Zhou X, Wu M. Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice. Am J Physiol Lung Cell Mol Physiol 307: L355-L363, 2014.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.307 , pp. L355-L363
    • Ye, Y.1    Li, X.2    Wang, W.3    Ouedraogo, K.C.4    Li, Y.5    Gan, C.6    Tan, S.7    Zhou, X.8    Wu, M.9
  • 117
    • 84948438613 scopus 로고    scopus 로고
    • Inhibition of p-IkappaBalpha ubiquitylation by autophagy-related gene 7 to regulate inflammatory responses to bacterial infection
    • Ye Y, Tan S, Zhou X, Li X, Jundt MC, Lichter N, Hidebrand A, Dhasarathy A, Wu M. Inhibition of p-IkappaBalpha ubiquitylation by autophagy-related gene 7 to regulate inflammatory responses to bacterial infection. J Infect Dis 212: 1816-1826, 2015.
    • (2015) J Infect Dis , vol.212 , pp. 1816-1826
    • Ye, Y.1    Tan, S.2    Zhou, X.3    Li, X.4    Jundt, M.C.5    Lichter, N.6    Hidebrand, A.7    Dhasarathy, A.8    Wu, M.9
  • 119
    • 84876406503 scopus 로고    scopus 로고
    • Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury
    • Yen YT, Yang HR, Lo HC, Hsieh YC, Tsai SC, Hong CW, Hsieh CH. Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury. Surgery 153: 689-698, 2013.
    • (2013) Surgery , vol.153 , pp. 689-698
    • Yen, Y.T.1    Yang, H.R.2    Lo, H.C.3    Hsieh, Y.C.4    Tsai, S.C.5    Hong, C.W.6    Hsieh, C.H.7
  • 121
    • 84865544952 scopus 로고    scopus 로고
    • Mitochondrial fission, fusion, and stress
    • Youle RJ, van der Bliek AM. Mitochondrial fission, fusion, and stress. Science 337: 1062-1065, 2012.
    • (2012) Science , vol.337 , pp. 1062-1065
    • Youle, R.J.1    Van Der Bliek, A.M.2
  • 122
    • 84879475204 scopus 로고    scopus 로고
    • Autophagy and mitophagy in cellular damage control
    • Zhang J. Autophagy and mitophagy in cellular damage control. Redox Biol 1: 19-23, 2013.
    • (2013) Redox Biol , vol.1 , pp. 19-23
    • Zhang, J.1
  • 123
    • 84904348591 scopus 로고    scopus 로고
    • Autophagy in pulmonary macrophages mediates lung inflammatory injury via NLRP3 inflammasome activation during mechanical ventilation
    • Zhang Y, Liu G, Dull RO, Schwartz DE, Hu G. Autophagy in pulmonary macrophages mediates lung inflammatory injury via NLRP3 inflammasome activation during mechanical ventilation. Am J Physiol Lung Cell Mol Physiol 307: L173-L185, 2014.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.307 , pp. L173-L185
    • Zhang, Y.1    Liu, G.2    Dull, R.O.3    Schwartz, D.E.4    Hu, G.5
  • 124
    • 84901252533 scopus 로고    scopus 로고
    • Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury
    • Zhang Y, Sauler M, Shinn AS, Gong H, Haslip M, Shan P, Mannam P, Lee PJ. Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury. J Immunol 192: 5296-5304, 2014.
    • (2014) J Immunol , vol.192 , pp. 5296-5304
    • Zhang, Y.1    Sauler, M.2    Shinn, A.S.3    Gong, H.4    Haslip, M.5    Shan, P.6    Mannam, P.7    Lee, P.J.8
  • 125
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 469: 221-225, 2011.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 127
    • 29944438881 scopus 로고    scopus 로고
    • Necrotic death as a cell fate
    • Zong WX, Thompson CB. Necrotic death as a cell fate. Genes Dev 20: 1-15, 2006.
    • (2006) Genes Dev , vol.20 , pp. 1-15
    • Zong, W.X.1    Thompson, C.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.