Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis

Immunity

Volumn 44, Issue 3, 2016, Pages 582-596

  Larson Casey, Jennifer L ^a   Deshane, Jessy S ^a   Ryan, Alan J ^b   Thannickal, Victor J ^a,c   Carter, A Brent ^a,c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA1; CYTOKINE; PARKIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROTECTION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; FIBROBLAST; GENE; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; MITOCHONDRION; MITOPHAGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; FIBROSING ALVEOLITIS; FIBROSIS; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG; METABOLISM; MUTANT MOUSE STRAIN; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CYTOKINES; FIBROSIS; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; LUNG; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SEQUENCE DELETION; UBIQUITIN-PROTEIN LIGASES;

EID: 84960392538     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.01.001     Document Type: Article

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