Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 307, Issue 5, 2014, Pages

  Ye, Yan ^a   Li, Xuefeng ^a   Wang, Wenxue ^a   Ouedraogo, Kiswendsida Claude ^a   Li, Yi ^a   Gan, Changpei ^a   Tan, Shirui ^a   Zhou, Xikun ^a   Wu, Min ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Alveolar macrophage; Autophagy; Autophagy related gene 7; Gram negative bacterial infection; Knockout mice; Lung injury; Reactive oxygen species

Indexed keywords

ALVEOLAR MACROPHAGE; AUTOPHAGY; AUTOPHAGY-RELATED GENE 7; GRAM-NEGATIVE BACTERIAL INFECTION; KNOCKOUT MICE; LUNG INJURY; REACTIVE OXYGEN SPECIES;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; INFLAMMATION MEDIATORS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LIPID PEROXIDATION; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; PNEUMONIA; PNEUMONIA, BACTERIAL; SURVIVAL RATE;

EID: 84906905024     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00046.2014     Document Type: Article

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