메뉴 건너뛰기




Volumn 4, Issue , 2015, Pages 215-225

Autophagy in lung disease pathogenesis and therapeutics

Author keywords

Autophagy; Cigarette smoke; Lung disease; Mitophagy; Reactive oxygen species

Indexed keywords

ADENYLATE KINASE; AUTOPHAGY PROTEIN 5; BECLIN 1; CHLOROQUINE; EARLY SECRETORY ANTIGENIC TARGET 6; HYDROXYCHLOROQUINE; IMMUNOGLOBULIN LIGHT CHAIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN KINASE B; PROTEIN P62; REACTIVE OXYGEN METABOLITE; SNARE PROTEIN; TRANSCRIPTION FACTOR NRF2; ACTIN BINDING PROTEIN; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; APOPTOSIS REGULATORY PROTEIN;

EID: 84921469717     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2014.12.010     Document Type: Article
Times cited : (121)

References (142)
  • 1
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: renovation of cells and tissues
    • Mizushima N., Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011, 147(4):728-741. http://www.ncbi.nlm.nih.gov/pubmed/22078875. 10.1016/j.cell.2011.10.026.
    • (2011) Cell , vol.147 , Issue.4 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 3
    • 84901833411 scopus 로고    scopus 로고
    • Autophagy and human disease: emerging themes
    • Schneider J.L., Cuervo A.M. Autophagy and human disease: emerging themes. Current Opinion in Genetics and Development 2014, 26C:16-23. http://www.ncbi.nlm.nih.gov/pubmed/24907664. 10.1016/j.gde.2014.04.003.
    • (2014) Current Opinion in Genetics and Development , vol.26 C , pp. 16-23
    • Schneider, J.L.1    Cuervo, A.M.2
  • 4
    • 84879475204 scopus 로고    scopus 로고
    • Autophagy and mitophagy in cellular damage control
    • Zhang J. Autophagy and mitophagy in cellular damage control. Redox Biology 2013, 1(1):19-23. http://www.ncbi.nlm.nih.gov/pubmed/23946931. 10.1016/j.redox.2012.11.008.
    • (2013) Redox Biology , vol.1 , Issue.1 , pp. 19-23
    • Zhang, J.1
  • 5
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B., Mizushima N., Virgin H.W. Autophagy in immunity and inflammation. Nature 2011, 469(7330):323-335. http://www.ncbi.nlm.nih.gov/pubmed/21248839. 10.1038/nature09782.
    • (2011) Nature , vol.469 , Issue.7330 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 7
    • 84913554278 scopus 로고    scopus 로고
    • Mitochondrial dynamics and mitochondrial quality control
    • Ni H.M., Williams J.A., Ding W.X. Mitochondrial dynamics and mitochondrial quality control. Redox Biology 2014, 4C:6-13. http://www.ncbi.nlm.nih.gov/pubmed/25479550. 10.1016/j.redox.2014.11.006.
    • (2014) Redox Biology , vol.4 C , pp. 6-13
    • Ni, H.M.1    Williams, J.A.2    Ding, W.X.3
  • 8
    • 84896867224 scopus 로고    scopus 로고
    • The impact of autophagy on cell death modalities
    • Ryter S.W., Mizumura K., Choi A.M. The impact of autophagy on cell death modalities. International Journal of Cell Biology 2014, 2014:502676. http://www.ncbi.nlm.nih.gov/pubmed/24639873. 10.1155/2014/502676.
    • (2014) International Journal of Cell Biology , vol.2014 , pp. 502676
    • Ryter, S.W.1    Mizumura, K.2    Choi, A.M.3
  • 9
    • 79955677000 scopus 로고    scopus 로고
    • Autophagic cell death: Loch Ness monster or endangered species?
    • Shen H.M., Codogno P. Autophagic cell death: Loch Ness monster or endangered species?. Autophagy 2011, 7(5):457-465. http://www.ncbi.nlm.nih.gov/pubmed/21150268. 10.4161/auto.7.5.14226.
    • (2011) Autophagy , vol.7 , Issue.5 , pp. 457-465
    • Shen, H.M.1    Codogno, P.2
  • 11
    • 84922541234 scopus 로고    scopus 로고
    • Autosis and autophagic cell death: the dark side of autophagy
    • (Epub ahead of print)
    • Liu Y., Levine B. Autosis and autophagic cell death: the dark side of autophagy. Cell Death & Differentiation 2014, (Epub ahead of print). http://www.ncbi.nlm.nih.gov/pubmed/25257169. 10.1038/cdd.2014.143.
    • (2014) Cell Death & Differentiation
    • Liu, Y.1    Levine, B.2
  • 12
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132(1):27-42. http://www.ncbi.nlm.nih.gov/pubmed/18191218. 10.1016/j.cell.2007.12.018.
    • (2008) Cell , vol.132 , Issue.1 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 13
    • 84866122688 scopus 로고    scopus 로고
    • Autophagy modulation as a potential therapeutic target for diverse diseases
    • Rubinsztein D.C., Codogno P., Levine B. Autophagy modulation as a potential therapeutic target for diverse diseases. Nature Reviews Drug Discovery 2012, 11(9):709-730. http://www.ncbi.nlm.nih.gov/pubmed/22935804. 10.1038/nrd3802.
    • (2012) Nature Reviews Drug Discovery , vol.11 , Issue.9 , pp. 709-730
    • Rubinsztein, D.C.1    Codogno, P.2    Levine, B.3
  • 14
    • 84873660610 scopus 로고    scopus 로고
    • Autophagy in human health and disease
    • Choi A.M., Ryter S.W., Levine B. Autophagy in human health and disease. New England Journal of Medicine 2013, 368(7):651-662. http://www.ncbi.nlm.nih.gov/pubmed/23406030. 10.1056/NEJMra1205406.
    • (2013) New England Journal of Medicine , vol.368 , Issue.7 , pp. 651-662
    • Choi, A.M.1    Ryter, S.W.2    Levine, B.3
  • 15
    • 84892163616 scopus 로고    scopus 로고
    • Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
    • Giordano S., Darley-Usmar V., Zhang J. Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. Redox Biology 2014, 2:82-90. http://www.ncbi.nlm.nih.gov/pubmed/24494187. 10.1016/j.redox.2013.12.013.
    • (2014) Redox Biology , vol.2 , pp. 82-90
    • Giordano, S.1    Darley-Usmar, V.2    Zhang, J.3
  • 16
    • 77956414236 scopus 로고    scopus 로고
    • The origin of the autophagosomal membrane
    • Tooze S.A., Yoshimori T. The origin of the autophagosomal membrane. Nature Cell Biology 2010, 12(9):831-835. http://www.ncbi.nlm.nih.gov/pubmed/20811355. 10.1038/ncb0910-831.
    • (2010) Nature Cell Biology , vol.12 , Issue.9 , pp. 831-835
    • Tooze, S.A.1    Yoshimori, T.2
  • 17
    • 84888627184 scopus 로고    scopus 로고
    • Location and membrane sources for autophagosome formation -from ER-mitochondria contact sites to Golgi-endosome-derived carriers
    • Chan S.N., Tang B.L. Location and membrane sources for autophagosome formation -from ER-mitochondria contact sites to Golgi-endosome-derived carriers. Molecular Membrane Biology 2013, 30(8):394-402. http://www.ncbi.nlm.nih.gov/pubmed/24175710. 10.3109/09687688.2013.850178.
    • (2013) Molecular Membrane Biology , vol.30 , Issue.8 , pp. 394-402
    • Chan, S.N.1    Tang, B.L.2
  • 19
    • 71649087199 scopus 로고    scopus 로고
    • A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation
    • Hayashi-Nishino M., Fujita N., Noda T., Yamaguchi A., Yoshimori T., Yamamoto A. A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation. Nature Cell Biology 2009, 11(12):1433-1437. http://www.ncbi.nlm.nih.gov/pubmed/19898463. 10.1038/ncb1991.
    • (2009) Nature Cell Biology , vol.11 , Issue.12 , pp. 1433-1437
    • Hayashi-Nishino, M.1    Fujita, N.2    Noda, T.3    Yamaguchi, A.4    Yoshimori, T.5    Yamamoto, A.6
  • 20
    • 71649112895 scopus 로고    scopus 로고
    • 3D tomography reveals connections between the phagophore and endoplasmic reticulum
    • Ylä-Anttila P., Vihinen H., Jokitalo E., Eskelinen E.L. 3D tomography reveals connections between the phagophore and endoplasmic reticulum. Autophagy 2009, 5(8):1180-1185. http://www.ncbi.nlm.nih.gov/pubmed/19855179. 10.4161/auto.5.8.10274.
    • (2009) Autophagy , vol.5 , Issue.8 , pp. 1180-1185
    • Ylä-Anttila, P.1    Vihinen, H.2    Jokitalo, E.3    Eskelinen, E.L.4
  • 21
    • 77952495224 scopus 로고    scopus 로고
    • Mitochondria supply membranes for autophagosome biogenesis during starvation
    • Hailey D.W., Rambold A.S., Satpute-Krishnan P., Mitra K., Sougrat R., Kim P.K., Lippincott-Schwartz J. Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 2010, 141(4):656-667. http://www.ncbi.nlm.nih.gov/pubmed/20478256. 10.1016/j.cell.2010.04.009.
    • (2010) Cell , vol.141 , Issue.4 , pp. 656-667
    • Hailey, D.W.1    Rambold, A.S.2    Satpute-Krishnan, P.3    Mitra, K.4    Sougrat, R.5    Kim, P.K.6    Lippincott-Schwartz, J.7
  • 22
    • 84897932103 scopus 로고    scopus 로고
    • Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of Parkin-associated mitophagy
    • Cook K.L., Soto-Pantoja D.R., Abu-Asab M., Clarke P.A., Roberts D.D., Clarke R. Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of Parkin-associated mitophagy. Cell & Bioscience 2014, 4(1):16. http://www.ncbi.nlm.nih.gov/pubmed/24669863. 10.1186/2045-3701-4-16.
    • (2014) Cell & Bioscience , vol.4 , Issue.1 , pp. 16
    • Cook, K.L.1    Soto-Pantoja, D.R.2    Abu-Asab, M.3    Clarke, P.A.4    Roberts, D.D.5    Clarke, R.6
  • 23
    • 77955131007 scopus 로고    scopus 로고
    • Plasma membrane contributes to the formation of pre-autophagosomal structures
    • Ravikumar B., Moreau K., Jahreiss L., Puri C., Rubinsztein D.C. Plasma membrane contributes to the formation of pre-autophagosomal structures. Nature Cell Biology 2010, 12(8):747-757. http://www.ncbi.nlm.nih.gov/pubmed/20639872. 10.1038/ncb2078.
    • (2010) Nature Cell Biology , vol.12 , Issue.8 , pp. 747-757
    • Ravikumar, B.1    Moreau, K.2    Jahreiss, L.3    Puri, C.4    Rubinsztein, D.C.5
  • 24
    • 84855645313 scopus 로고    scopus 로고
    • Mechanisms of autophagosome biogenesis
    • Rubinsztein D.C., Shpilka T., Elazar Z. Mechanisms of autophagosome biogenesis. Current Biology 2012, 22(1):R29-R34. http://www.ncbi.nlm.nih.gov/pubmed/22240478. 10.1016/j.cub.2011.11.034.
    • (2012) Current Biology , vol.22 , Issue.1 , pp. R29-R34
    • Rubinsztein, D.C.1    Shpilka, T.2    Elazar, Z.3
  • 25
    • 84891747382 scopus 로고    scopus 로고
    • The machinery of macroautophagy
    • Feng Y., He D., Yao Z., Klionsky D.J. The machinery of macroautophagy. Cell Research 2014, 24(1):24-41. http://www.ncbi.nlm.nih.gov/pubmed/24366339. 10.1038/cr.2013.168.
    • (2014) Cell Research , vol.24 , Issue.1 , pp. 24-41
    • Feng, Y.1    He, D.2    Yao, Z.3    Klionsky, D.J.4
  • 26
    • 77951214016 scopus 로고    scopus 로고
    • Mammalian autophagy: core molecular machinery and signaling regulation
    • Yang Z., Klionsky D.J. Mammalian autophagy: core molecular machinery and signaling regulation. Current Opinion in Cell Biology 2010, 22(2):124-131. http://www.ncbi.nlm.nih.gov/pubmed/20034776. 10.1016/j.ceb.2009.11.014.
    • (2010) Current Opinion in Cell Biology , vol.22 , Issue.2 , pp. 124-131
    • Yang, Z.1    Klionsky, D.J.2
  • 27
    • 77950501014 scopus 로고    scopus 로고
    • MTOR regulation of autophagy
    • Jung C.H., Ro S.H., Cao J., Otto N.M., Kim D.H. mTOR regulation of autophagy. FEBS Letters 2010, 584(7):1287-1295. http://www.ncbi.nlm.nih.gov/pubmed/20083114. 10.1016/j.febslet.2010.01.017.
    • (2010) FEBS Letters , vol.584 , Issue.7 , pp. 1287-1295
    • Jung, C.H.1    Ro, S.H.2    Cao, J.3    Otto, N.M.4    Kim, D.H.5
  • 28
    • 47049127002 scopus 로고    scopus 로고
    • Regulation of proline-rich Akt substrate of 40kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation
    • Wang L., Harris T.E., Lawrence J.C. Regulation of proline-rich Akt substrate of 40kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation. Journal of Biological Chemistry 2008, 283(23):15619-15627. http://www.ncbi.nlm.nih.gov/pubmed/18372248. 10.1074/jbc.M800723200.
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.23 , pp. 15619-15627
    • Wang, L.1    Harris, T.E.2    Lawrence, J.C.3
  • 29
    • 84863499345 scopus 로고    scopus 로고
    • Regulation and function of uncoordinated-51 like kinase proteins
    • Chan E.Y. Regulation and function of uncoordinated-51 like kinase proteins. Antioxidants & Redox Signaling 2012, 17(5):775-785. http://www.ncbi.nlm.nih.gov/pubmed/22074133. 10.1089/ars.2011.4396.
    • (2012) Antioxidants & Redox Signaling , vol.17 , Issue.5 , pp. 775-785
    • Chan, E.Y.1
  • 30
    • 84873675067 scopus 로고    scopus 로고
    • The ULK1 complex: sensing nutrient signals for autophagy activation
    • Wong P.M., Puente C., Ganley I.G., Jiang X. The ULK1 complex: sensing nutrient signals for autophagy activation. Autophagy 2013, 9(2):124-137. http://www.ncbi.nlm.nih.gov/pubmed/23295650. 10.4161/auto.23323.
    • (2013) Autophagy , vol.9 , Issue.2 , pp. 124-137
    • Wong, P.M.1    Puente, C.2    Ganley, I.G.3    Jiang, X.4
  • 31
    • 66449083078 scopus 로고    scopus 로고
    • ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
    • Ganley I.G., Lam, [!(%xInRef|ce:surname)!] du H., Wang J., Ding X., Chen S., Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. Journal of Biological Chemistry 2009, 284(18):12297-12305. http://www.ncbi.nlm.nih.gov/pubmed/19258318. 10.1074/jbc.M900573200.
    • (2009) Journal of Biological Chemistry , vol.284 , Issue.18 , pp. 12297-12305
    • Ganley, I.G.1    Lam, D.H.2    Wang, J.3    Ding, X.4    Chen, S.5    Jiang, X.6
  • 33
    • 65249176304 scopus 로고    scopus 로고
    • ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
    • Jung C.H., Jun C.B., Ro S.H., Kim Y.M., Otto N.M., Cao J., Kundu M., Kim D.H. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Molecular Biology of the Cell 2009, 20(7):1992-2003. http://www.ncbi.nlm.nih.gov/pubmed/19225151. 10.1091/mbc.E08-12-1249.
    • (2009) Molecular Biology of the Cell , vol.20 , Issue.7 , pp. 1992-2003
    • Jung, C.H.1    Jun, C.B.2    Ro, S.H.3    Kim, Y.M.4    Otto, N.M.5    Cao, J.6    Kundu, M.7    Kim, D.H.8
  • 34
    • 78149476877 scopus 로고    scopus 로고
    • The association of AMPK with ULK1 regulates autophagy
    • Lee J.W., Park S., Takahashi Y., Wang H.G. The association of AMPK with ULK1 regulates autophagy. PLOS One 2010, 5(11):e15394. http://www.ncbi.nlm.nih.gov/pubmed/21072212. 10.1371/journal.pone.0015394.
    • (2010) PLOS One , vol.5 , Issue.11 , pp. e15394
    • Lee, J.W.1    Park, S.2    Takahashi, Y.3    Wang, H.G.4
  • 35
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • Kim J., Kundu M., Viollet B., Guan K.L. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nature Cell Biology 2011, 13(2):132-141. http://www.ncbi.nlm.nih.gov/pubmed/21258367. 10.1038/ncb2152.
    • (2011) Nature Cell Biology , vol.13 , Issue.2 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3    Guan, K.L.4
  • 36
    • 84866061320 scopus 로고    scopus 로고
    • AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization
    • Mack H.I., Zheng B., Asara J.M., Thomas S.M. AMPK-dependent phosphorylation of ULK1 regulates ATG9 localization. Autophagy 2012, 8(8):1197-1214. http://www.ncbi.nlm.nih.gov/pubmed/22932492. 10.4161/auto.20586.
    • (2012) Autophagy , vol.8 , Issue.8 , pp. 1197-1214
    • Mack, H.I.1    Zheng, B.2    Asara, J.M.3    Thomas, S.M.4
  • 37
    • 77951237303 scopus 로고    scopus 로고
    • The Beclin 1 interactome
    • He C., Levine B. The Beclin 1 interactome. Current Opinion in Cell Biology 2010, 22(2):140-149. http://www.ncbi.nlm.nih.gov/pubmed/20097051. 10.1016/j.ceb.2010.01.001.
    • (2010) Current Opinion in Cell Biology , vol.22 , Issue.2 , pp. 140-149
    • He, C.1    Levine, B.2
  • 38
    • 59249089394 scopus 로고    scopus 로고
    • Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
    • Itakura E., Kishi C., Inoue K., Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Molecular Biology of the Cell 2008, 19(12):5360-5372. http://www.ncbi.nlm.nih.gov/pubmed/18843052. 10.1091/mbc.E08-01-0080.
    • (2008) Molecular Biology of the Cell , vol.19 , Issue.12 , pp. 5360-5372
    • Itakura, E.1    Kishi, C.2    Inoue, K.3    Mizushima, N.4
  • 40
    • 84880343182 scopus 로고    scopus 로고
    • ULK1 targets Beclin-1 in autophagy
    • Nazarko V.Y., Zhong Q. ULK1 targets Beclin-1 in autophagy. Nature Cell Biology 2013, 15(7):727-728. http://www.ncbi.nlm.nih.gov/pubmed/23817237. 10.1038/ncb2797.
    • (2013) Nature Cell Biology , vol.15 , Issue.7 , pp. 727-728
    • Nazarko, V.Y.1    Zhong, Q.2
  • 41
    • 84884819157 scopus 로고    scopus 로고
    • Autophagosome formation -the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage
    • Wirth M., Joachim J., Tooze S.A. Autophagosome formation -the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage. Seminars in Cancer Biology 2013, 23(5):301-309. http://www.ncbi.nlm.nih.gov/pubmed/23727157. 10.1016/j.semcancer.2013.05.007.
    • (2013) Seminars in Cancer Biology , vol.23 , Issue.5 , pp. 301-309
    • Wirth, M.1    Joachim, J.2    Tooze, S.A.3
  • 42
    • 84904575441 scopus 로고    scopus 로고
    • WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1
    • Dooley H.C., Razi M., Polson H.E., Girardin S.E., Wilson M.I., Tooze S.A. WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. Molecular Cell 2014, 55(2):238-252. http://www.ncbi.nlm.nih.gov/pubmed/24954904. 10.1016/j.molcel.2014.05.021.
    • (2014) Molecular Cell , vol.55 , Issue.2 , pp. 238-252
    • Dooley, H.C.1    Razi, M.2    Polson, H.E.3    Girardin, S.E.4    Wilson, M.I.5    Tooze, S.A.6
  • 43
    • 79960774898 scopus 로고    scopus 로고
    • Autophagosome precursor maturation requires homotypic fusion
    • Moreau K., Ravikumar B., Renna M., Puri C., Rubinsztein D.C. Autophagosome precursor maturation requires homotypic fusion. Cell 2011, 146(2):303-317. http://www.ncbi.nlm.nih.gov/pubmed/21784250. 10.1016/j.cell.2011.06.023.
    • (2011) Cell , vol.146 , Issue.2 , pp. 303-317
    • Moreau, K.1    Ravikumar, B.2    Renna, M.3    Puri, C.4    Rubinsztein, D.C.5
  • 45
    • 84892154950 scopus 로고    scopus 로고
    • Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy
    • Nakatogawa H. Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy. Essays in Biochemistry 2013, 55:39-50. http://www.ncbi.nlm.nih.gov/pubmed/24070470. 10.1042/bse0550039.
    • (2013) Essays in Biochemistry , vol.55 , pp. 39-50
    • Nakatogawa, H.1
  • 46
    • 3242888703 scopus 로고    scopus 로고
    • LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
    • Kabeya Y., Mizushima N., Yamamoto A., Oshitani-Okamoto S., Ohsumi Y., Yoshimori T. LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. Journal of Cell Science 2004, 117(13):2805-2812. http://www.ncbi.nlm.nih.gov/pubmed/15169837. 10.1242/jcs.01131.
    • (2004) Journal of Cell Science , vol.117 , Issue.13 , pp. 2805-2812
    • Kabeya, Y.1    Mizushima, N.2    Yamamoto, A.3    Oshitani-Okamoto, S.4    Ohsumi, Y.5    Yoshimori, T.6
  • 47
    • 84892146575 scopus 로고    scopus 로고
    • Selective autophagy
    • Svenning S., Johansen T. Selective autophagy. Essays in Biochemistry 2013, 55:79-92. http://www.ncbi.nlm.nih.gov/pubmed/24070473. 10.1042/bse0550079.
    • (2013) Essays in Biochemistry , vol.55 , pp. 79-92
    • Svenning, S.1    Johansen, T.2
  • 48
    • 84901815187 scopus 로고    scopus 로고
    • Cargo recognition and trafficking in selective autophagy
    • Stolz A., Ernst A., Dikic I. Cargo recognition and trafficking in selective autophagy. Nature Cell Biology 2014, 16(6):495-501. http://www.ncbi.nlm.nih.gov/pubmed/24875736. 10.1038/ncb2979.
    • (2014) Nature Cell Biology , vol.16 , Issue.6 , pp. 495-501
    • Stolz, A.1    Ernst, A.2    Dikic, I.3
  • 49
    • 84870980670 scopus 로고    scopus 로고
    • Ubiquitination and selective autophagy
    • Shaid S., Brandts C.H., Serve H., Dikic I. Ubiquitination and selective autophagy. Cell Death and Differentiation 2013, 20(1):21-30. http://www.ncbi.nlm.nih.gov/pubmed/22722335. 10.1038/cdd.2012.72.
    • (2013) Cell Death and Differentiation , vol.20 , Issue.1 , pp. 21-30
    • Shaid, S.1    Brandts, C.H.2    Serve, H.3    Dikic, I.4
  • 50
    • 84903555177 scopus 로고    scopus 로고
    • The role of the selective adaptor p62 and ubiquitin-like proteins in autophagy
    • Lippai M., Low P. The role of the selective adaptor p62 and ubiquitin-like proteins in autophagy. BioMed Research International 2014, 2014:832704. http://www.ncbi.nlm.nih.gov/pubmed/25013806. 10.1155/2014/832704.
    • (2014) BioMed Research International , vol.2014 , pp. 832704
    • Lippai, M.1    Low, P.2
  • 53
    • 84899539731 scopus 로고    scopus 로고
    • PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
    • Kane L.A., Lazarou M., Fogel A.I., Li Y., Yamano K., Sarraf S.A., Banerjee S., Youle R.J. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. Journal of Cell Biology 2014, 205(2):143-153. http://www.ncbi.nlm.nih.gov/pubmed/24751536. 10.1083/jcb.201402104.
    • (2014) Journal of Cell Biology , vol.205 , Issue.2 , pp. 143-153
    • Kane, L.A.1    Lazarou, M.2    Fogel, A.I.3    Li, Y.4    Yamano, K.5    Sarraf, S.A.6    Banerjee, S.7    Youle, R.J.8
  • 54
    • 79955949858 scopus 로고    scopus 로고
    • The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration
    • Yamamoto A., Simonsen A. The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration. Neurobiology of Disease 2011, 43(1):17-28. http://www.ncbi.nlm.nih.gov/pubmed/20732422. 10.1016/j.nbd.2010.08.015.
    • (2011) Neurobiology of Disease , vol.43 , Issue.1 , pp. 17-28
    • Yamamoto, A.1    Simonsen, A.2
  • 56
    • 84892576077 scopus 로고    scopus 로고
    • Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease
    • Nakahira K., Cloonan S.M., Mizumura K., Choi A.M., Ryter S.W. Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease. Antioxidants & Redox Signaling 2014, 20(3):474-494. http://www.ncbi.nlm.nih.gov/pubmed/23879400. 10.1089/ars.2013.5373.
    • (2014) Antioxidants & Redox Signaling , vol.20 , Issue.3 , pp. 474-494
    • Nakahira, K.1    Cloonan, S.M.2    Mizumura, K.3    Choi, A.M.4    Ryter, S.W.5
  • 57
    • 36749010860 scopus 로고    scopus 로고
    • Biochemistry of oxidative stress
    • Halliwell B. Biochemistry of oxidative stress. Biochemical Society Transactions 2007, 35(5):1147-1150. http://www.ncbi.nlm.nih.gov/pubmed/17956298. 10.1042/BST0351147.
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1147-1150
    • Halliwell, B.1
  • 58
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Dröge W. Free radicals in the physiological control of cell function. Physiological Reviews 2002, 82(1):47-95. http://www.ncbi.nlm.nih.gov/pubmed/11773609. 10.1152/physrev.00018.2001.
    • (2002) Physiological Reviews , vol.82 , Issue.1 , pp. 47-95
    • Dröge, W.1
  • 59
    • 33644643603 scopus 로고    scopus 로고
    • Oxidative stress and autophagy
    • Kiffin R., Bandyopadhyay U., Cuervo A.M. Oxidative stress and autophagy. Antioxidants & Redox Signaling 2006, 8(1-2):152-162. http://www.ncbi.nlm.nih.gov/pubmed/16487049. 10.1089/ars.2006.8.152.
    • (2006) Antioxidants & Redox Signaling , vol.8 , Issue.1-2 , pp. 152-162
    • Kiffin, R.1    Bandyopadhyay, U.2    Cuervo, A.M.3
  • 60
    • 60749108379 scopus 로고    scopus 로고
    • Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment
    • Azad M.B., Chen Y., Gibson S.B. Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment. Antioxidants & Redox Signaling 2009, 11(4):777-790. http://www.ncbi.nlm.nih.gov/pubmed/18828708. 10.1089/ARS.2008.2270.
    • (2009) Antioxidants & Redox Signaling , vol.11 , Issue.4 , pp. 777-790
    • Azad, M.B.1    Chen, Y.2    Gibson, S.B.3
  • 61
    • 38349043984 scopus 로고    scopus 로고
    • Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species
    • Chen Y., McMillan-Ward E., Kong J., Israels S.J., Gibson S.B. Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. Journal of Cell Science 2007, 120(23):4155-4166. http://www.ncbi.nlm.nih.gov/pubmed/18032788. 10.1242/jcs.011163.
    • (2007) Journal of Cell Science , vol.120 , Issue.23 , pp. 4155-4166
    • Chen, Y.1    McMillan-Ward, E.2    Kong, J.3    Israels, S.J.4    Gibson, S.B.5
  • 62
    • 37349067228 scopus 로고    scopus 로고
    • Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
    • Chen Y., McMillan-Ward E., Kong J., Israels S.J., Gibson S.B. Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death and Differentiation 2008, 15(1):171-182. http://www.ncbi.nlm.nih.gov/pubmed/17917680. 10.1038/sj.cdd.4402233.
    • (2008) Cell Death and Differentiation , vol.15 , Issue.1 , pp. 171-182
    • Chen, Y.1    McMillan-Ward, E.2    Kong, J.3    Israels, S.J.4    Gibson, S.B.5
  • 63
    • 67549084381 scopus 로고    scopus 로고
    • Superoxide is the major reactive oxygen species regulating autophagy
    • Chen Y., Azad M.B., Gibson S.B. Superoxide is the major reactive oxygen species regulating autophagy. Cell Death and Differentiation 2009, 16(7):1040-1052. http://www.ncbi.nlm.nih.gov/pubmed/19407826. 10.1038/cdd.2009.49.
    • (2009) Cell Death and Differentiation , vol.16 , Issue.7 , pp. 1040-1052
    • Chen, Y.1    Azad, M.B.2    Gibson, S.B.3
  • 64
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • Scherz-Shouval R., Shvets E., Fass E., Shorer H., Gil L., Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO Journal 2007, 26(7):1749-1760. http://www.ncbi.nlm.nih.gov/pubmed/17347651. 10.1038/sj.emboj.7601623.
    • (2007) EMBO Journal , vol.26 , Issue.7 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 68
    • 84867724832 scopus 로고    scopus 로고
    • Mitochondria and mitophagy: the yin and yang of cell death control
    • Kubli D.A., Gustafsson Å.B. Mitochondria and mitophagy: the yin and yang of cell death control. Circulation Research 2012, 111(9):1208-1221. http://www.ncbi.nlm.nih.gov/pubmed/23065344. 10.1161/CIRCRESAHA.112.265819.
    • (2012) Circulation Research , vol.111 , Issue.9 , pp. 1208-1221
    • Kubli, D.A.1    Gustafsson, Å.B.2
  • 69
    • 77954599053 scopus 로고    scopus 로고
    • P62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
    • Jain A., Lamark T., Sjøttem E., Larsen K.B., Awuh J.A., Øvervatn A., McMahon M., Hayes J.D., Johansen T. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. Journal of Biological Chemistry 2010, 285(29):22576-22591. http://www.ncbi.nlm.nih.gov/pubmed/20452972. 10.1074/jbc.M110.118976.
    • (2010) Journal of Biological Chemistry , vol.285 , Issue.29 , pp. 22576-22591
    • Jain, A.1    Lamark, T.2    Sjøttem, E.3    Larsen, K.B.4    Awuh, J.A.5    Øvervatn, A.6    McMahon, M.7    Hayes, J.D.8    Johansen, T.9
  • 74
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K., Tschopp J. The inflammasomes. Cell 2010, 140(6):821-832. http://www.ncbi.nlm.nih.gov/pubmed/20303873. 10.1016/j.cell.2010.01.040.
    • (2010) Cell , vol.140 , Issue.6 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 75
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R., Yazdi A.S., Menu P., Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011, 469(7329):221-225. http://www.ncbi.nlm.nih.gov/pubmed/21124315. 10.1038/nature09663.
    • (2011) Nature , vol.469 , Issue.7329 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 76
    • 84913529685 scopus 로고    scopus 로고
    • Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicity
    • Yang S., Xia C., Li S., Du L., Zhang L., Zhou R. Defective mitophagy driven by dysregulation of rheb and KIF5B contributes to mitochondrial reactive oxygen species (ROS)-induced nod-like receptor 3 (NLRP3) dependent proinflammatory response and aggravates lipotoxicity. Redox Biology 2014, 3:63-71. http://www.ncbi.nlm.nih.gov/pubmed/25462067. 10.1016/j.redox.2014.04.001.
    • (2014) Redox Biology , vol.3 , pp. 63-71
    • Yang, S.1    Xia, C.2    Li, S.3    Du, L.4    Zhang, L.5    Zhou, R.6
  • 77
    • 84908158678 scopus 로고    scopus 로고
    • MTOR and autophagy in regulation of acute lung injury: a review and perspective
    • (Epub ahead of print)
    • Hu Y., Liu J., Wu Y.F., Lou J., Mao Y.Y., Shen H.H., Chen Z.H. mTOR and autophagy in regulation of acute lung injury: a review and perspective. Microbes and Infection 2014, 16(9):727-734. (Epub ahead of print). 10.1016/j.micinf.2014.07.005.
    • (2014) Microbes and Infection , vol.16 , Issue.9 , pp. 727-734
    • Hu, Y.1    Liu, J.2    Wu, Y.F.3    Lou, J.4    Mao, Y.Y.5    Shen, H.H.6    Chen, Z.H.7
  • 78
    • 0022559220 scopus 로고
    • Morphologic changes in pulmonary oxygen toxicity
    • Crapo J.D. Morphologic changes in pulmonary oxygen toxicity. Annual Review of Physiology 1986, 48:721-731. http://www.ncbi.nlm.nih.gov/pubmed/3518622. 10.1146/annurev.ph.48.030186.003445.
    • (1986) Annual Review of Physiology , vol.48 , pp. 721-731
    • Crapo, J.D.1
  • 80
    • 84917743297 scopus 로고    scopus 로고
    • Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis
    • [Epub ahead of print]
    • Chang A.L., Ulrich A., Suliman H.B., Piantadosi C.A. Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis. Free Radical Biology and Medicine 2015, [Epub ahead of print]. 10.1016/j.freeradbiomed.2014.10.582.
    • (2015) Free Radical Biology and Medicine
    • Chang, A.L.1    Ulrich, A.2    Suliman, H.B.3    Piantadosi, C.A.4
  • 82
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • Gutierrez M.G., Master S.S., Singh S.B., Taylor G.A., Colombo M.I., Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004, 119(6):753-766. http://www.ncbi.nlm.nih.gov/pubmed/15607973. 10.1016/j.cell.2004.11.038.
    • (2004) Cell , vol.119 , Issue.6 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 83
    • 64749091309 scopus 로고    scopus 로고
    • Antimicrobial mechanisms of phagocytes and bacterial evasion strategies
    • Flannagan R.S., Cosío G., Grinstein S. Antimicrobial mechanisms of phagocytes and bacterial evasion strategies. Nature Reviews Microbiology 2009, 7(5):355-366. http://www.ncbi.nlm.nih.gov/pubmed/19369951. 10.1038/nrmicro2128.
    • (2009) Nature Reviews Microbiology , vol.7 , Issue.5 , pp. 355-366
    • Flannagan, R.S.1    Cosío, G.2    Grinstein, S.3
  • 84
    • 80052679702 scopus 로고    scopus 로고
    • Tuberculosis: new aspects of an old disease
    • Jordao L., Vieira O.V. Tuberculosis: new aspects of an old disease. International Journal of Cell Biology 2011, 2011:403623. http://www.ncbi.nlm.nih.gov/pubmed/21760796. 10.1155/2011/403623.
    • (2011) International Journal of Cell Biology , vol.2011 , pp. 403623
    • Jordao, L.1    Vieira, O.V.2
  • 85
  • 86
    • 52549123569 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence
    • Gan H., Lee J., Ren F., Chen M., Kornfeld H., Remold H.G. Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence. Nature Immunology 2008, 9(10):1189-1197. http://www.ncbi.nlm.nih.gov/pubmed/18794848. 10.1038/ni.1654.
    • (2008) Nature Immunology , vol.9 , Issue.10 , pp. 1189-1197
    • Gan, H.1    Lee, J.2    Ren, F.3    Chen, M.4    Kornfeld, H.5    Remold, H.G.6
  • 87
    • 75649145030 scopus 로고    scopus 로고
    • Autophagy in immunity against Mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy
    • Deretic V., Delgado M., Vergne I., Master S., De Haro S., Ponpuak M., Singh S. Autophagy in immunity against Mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy. Current Topics in Microbiology and Immunology 2009, 335:169-188. http://www.ncbi.nlm.nih.gov/pubmed/19802565. 10.1007/978-3-642-00302-8_8.
    • (2009) Current Topics in Microbiology and Immunology , vol.335 , pp. 169-188
    • Deretic, V.1    Delgado, M.2    Vergne, I.3    Master, S.4    De Haro, S.5    Ponpuak, M.6    Singh, S.7
  • 88
    • 62049084947 scopus 로고    scopus 로고
    • Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
    • Jagannath C., Lindsey D.R., Dhandayuthapani S., Xu Y., Hunter R.L., Eissa N.T. Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nature Medicine 2009, 15(3):267-276. http://www.ncbi.nlm.nih.gov/pubmed/19252503. 10.1038/nm.1928.
    • (2009) Nature Medicine , vol.15 , Issue.3 , pp. 267-276
    • Jagannath, C.1    Lindsey, D.R.2    Dhandayuthapani, S.3    Xu, Y.4    Hunter, R.L.5    Eissa, N.T.6
  • 89
    • 84863671626 scopus 로고    scopus 로고
    • Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis
    • Lam K.K., Zheng X., Forestieri R., Balgi A.D., Nodwell M., Vollett S., Anderson H.J., Andersen R.J., Av-Gay Y., Roberge M. Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. PLOS Pathogens 2012, 8(5). http://www.ncbi.nlm.nih.gov/pubmed/22589723. 10.1371/journal.ppat.1002691.
    • (2012) PLOS Pathogens , vol.8 , Issue.5
    • Lam, K.K.1    Zheng, X.2    Forestieri, R.3    Balgi, A.D.4    Nodwell, M.5    Vollett, S.6    Anderson, H.J.7    Andersen, R.J.8    Av-Gay, Y.9    Roberge, M.10
  • 90
    • 35848965721 scopus 로고    scopus 로고
    • Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages
    • Floto R.A., Sarkar S., Perlstein E.O., Kampmann B., Schreiber S.L., Rubinsztein D.C. Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages. Autophagy 2007, 3(6):620-662. http://www.ncbi.nlm.nih.gov/pubmed/17786022. 10.4161/auto.4898.
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 620-662
    • Floto, R.A.1    Sarkar, S.2    Perlstein, E.O.3    Kampmann, B.4    Schreiber, S.L.5    Rubinsztein, D.C.6
  • 91
    • 77949997805 scopus 로고    scopus 로고
    • Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties
    • Ponpuak M., Davis A.S., Roberts E.A., Delgado M.A., Dinkins C., Zhao Z., Virgin H.W., Kyei G.B., Johansen T., Vergne I., Deretic V. Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. Immunity 2010, 32(3):329-341. http://www.ncbi.nlm.nih.gov/pubmed/20206555. 10.1016/j.immuni.2010.02.009.
    • (2010) Immunity , vol.32 , Issue.3 , pp. 329-341
    • Ponpuak, M.1    Davis, A.S.2    Roberts, E.A.3    Delgado, M.A.4    Dinkins, C.5    Zhao, Z.6    Virgin, H.W.7    Kyei, G.B.8    Johansen, T.9    Vergne, I.10    Deretic, V.11
  • 93
    • 33748506089 scopus 로고    scopus 로고
    • Human IRGM induces autophagy to eliminate intracellular mycobacteria
    • Singh S.B., Davis A.S., Taylor G.A., Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006, 313(5792):1438-1441. http://www.ncbi.nlm.nih.gov/pubmed/16888103. 10.1126/science.1129577.
    • (2006) Science , vol.313 , Issue.5792 , pp. 1438-1441
    • Singh, S.B.1    Davis, A.S.2    Taylor, G.A.3    Deretic, V.4
  • 94
    • 0142240338 scopus 로고    scopus 로고
    • Immune control of tuberculosis by IFN-gamma-inducible LRG-47
    • MacMicking J.D., Taylor G.A., McKinney J.D. Immune control of tuberculosis by IFN-gamma-inducible LRG-47. Science 2003, 302(5645):654-659. http://www.ncbi.nlm.nih.gov/pubmed/14576437. 10.1126/science.1088063.
    • (2003) Science , vol.302 , Issue.5645 , pp. 654-659
    • MacMicking, J.D.1    Taylor, G.A.2    McKinney, J.D.3
  • 96
    • 84865220380 scopus 로고    scopus 로고
    • Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway
    • Watson R.O., Manzanillo P.S., Cox J.S. Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway. Cell 2012, 150(4):803-815. http://www.ncbi.nlm.nih.gov/pubmed/22901810. 10.1016/j.cell.2012.06.040.
    • (2012) Cell , vol.150 , Issue.4 , pp. 803-815
    • Watson, R.O.1    Manzanillo, P.S.2    Cox, J.S.3
  • 97
    • 77954187960 scopus 로고    scopus 로고
    • Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila
    • Tung S.M., Unal C., Ley A., Peña C., Tunggal B., Noegel A.A., Krut O., Steinert M., Eichinger L. Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila. Cellular Microbiology 2010, 12(6):765-780. http://www.ncbi.nlm.nih.gov/pubmed/20070309. 10.1111/j.1462-5822.2010.01432.x.
    • (2010) Cellular Microbiology , vol.12 , Issue.6 , pp. 765-780
    • Tung, S.M.1    Unal, C.2    Ley, A.3    Peña, C.4    Tunggal, B.5    Noegel, A.A.6    Krut, O.7    Steinert, M.8    Eichinger, L.9
  • 98
    • 84906905024 scopus 로고    scopus 로고
    • Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice
    • Ye Y., Li X., Wang W., Ouedraogo K.C., Li Y., Gan C., Tan S., Zhou X., Wu M. Atg7 deficiency impairs host defense against Klebsiella pneumoniae by impacting bacterial clearance, survival and inflammatory responses in mice. American Journal of Physiology - Lung Cellular and Molecular Physiology 2014, 307(5):L355-L363. http://www.ncbi.nlm.nih.gov/pubmed/24993132. 10.1152/ajplung.00046.2014.
    • (2014) American Journal of Physiology - Lung Cellular and Molecular Physiology , vol.307 , Issue.5 , pp. L355-L363
    • Ye, Y.1    Li, X.2    Wang, W.3    Ouedraogo, K.C.4    Li, Y.5    Gan, C.6    Tan, S.7    Zhou, X.8    Wu, M.9
  • 99
    • 84899553077 scopus 로고    scopus 로고
    • The regulation of autophagy by influenza A virus
    • Zhang R., Chi X., Wang S., Qi B., Yu X., Chen J.L. The regulation of autophagy by influenza A virus. BioMed Research International 2014, 2014:498083. http://www.ncbi.nlm.nih.gov/pubmed/24779013. 10.1155/2014/498083.Epub.
    • (2014) BioMed Research International , vol.2014 , pp. 498083
    • Zhang, R.1    Chi, X.2    Wang, S.3    Qi, B.4    Yu, X.5    Chen, J.L.6
  • 101
    • 84902954600 scopus 로고    scopus 로고
    • Essential role for autophagy in the maintenance of immunological memory against influenza infection
    • Chen M., Hong M.J., Sun H., Wang L., Shi X., Gilbert B.E., Corry D.B., Kheradmand F., Wang J. Essential role for autophagy in the maintenance of immunological memory against influenza infection. Nature Medicine 2014, 20(5):503-510. http://www.ncbi.nlm.nih.gov/pubmed/24747745. 10.1038/nm.3521.
    • (2014) Nature Medicine , vol.20 , Issue.5 , pp. 503-510
    • Chen, M.1    Hong, M.J.2    Sun, H.3    Wang, L.4    Shi, X.5    Gilbert, B.E.6    Corry, D.B.7    Kheradmand, F.8    Wang, J.9
  • 102
    • 5344233478 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension
    • Farber H.W., Loscalzo J. Pulmonary arterial hypertension. New England Journal of Medicine 2004, 351(16):1655-1665. http://www.ncbi.nlm.nih.gov/pubmed/15483284. 10.1056/NEJMra035488.
    • (2004) New England Journal of Medicine , vol.351 , Issue.16 , pp. 1655-1665
    • Farber, H.W.1    Loscalzo, J.2
  • 103
    • 84872082742 scopus 로고    scopus 로고
    • Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension
    • Dromparis P., Paulin R., Stenson T.H., Haromy A., Sutendra G., Michelakis E.D. Attenuating endoplasmic reticulum stress as a novel therapeutic strategy in pulmonary hypertension. Circulation 2013, 127(1):115-125. http://www.ncbi.nlm.nih.gov/pubmed/23149668. 10.1161/CIRCULATIONAHA.112.133413.
    • (2013) Circulation , vol.127 , Issue.1 , pp. 115-125
    • Dromparis, P.1    Paulin, R.2    Stenson, T.H.3    Haromy, A.4    Sutendra, G.5    Michelakis, E.D.6
  • 104
    • 80051625243 scopus 로고    scopus 로고
    • Oxygen sensing, homeostasis, and disease
    • Semenza G.L. Oxygen sensing, homeostasis, and disease. New England Journal of Medicine 2011, 365(6):537-547. http://www.ncbi.nlm.nih.gov/pubmed/21830968. 10.1056/NEJMra1011165.
    • (2011) New England Journal of Medicine , vol.365 , Issue.6 , pp. 537-547
    • Semenza, G.L.1
  • 105
    • 33749345684 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms
    • Stenmark K.R., Fagan K.A., Frid M.G. Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms. Circulation Research 2006, 99(7):675-691. http://www.ncbi.nlm.nih.gov/pubmed/17008597. 10.1161/01.RES.0000243584.45145.3f.
    • (2006) Circulation Research , vol.99 , Issue.7 , pp. 675-691
    • Stenmark, K.R.1    Fagan, K.A.2    Frid, M.G.3
  • 107
    • 84906667178 scopus 로고    scopus 로고
    • MTORC1 is involved in hypoxia-induced pulmonary hypertension through the activation of Notch3
    • Wang W., Liu J., Ma A., Miao R., Jin Y., Zhang H., Xu K., Wang C., Wang J. mTORC1 is involved in hypoxia-induced pulmonary hypertension through the activation of Notch3. Journal of Cellular Physiology 2014, 229(12):2117-2125. http://www.ncbi.nlm.nih.gov/pubmed/24825564. 10.1002/jcp.24670.
    • (2014) Journal of Cellular Physiology , vol.229 , Issue.12 , pp. 2117-2125
    • Wang, W.1    Liu, J.2    Ma, A.3    Miao, R.4    Jin, Y.5    Zhang, H.6    Xu, K.7    Wang, C.8    Wang, J.9
  • 108
    • 84859447737 scopus 로고    scopus 로고
    • Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension
    • Teng R.J., Du J., Welak S., Guan T., Eis A., Shi Y., Konduri G.G. Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension. American Journal of Physiology - Lung Cellular and Molecular Physiology 2012, 302(7):L651-L663. http://www.ncbi.nlm.nih.gov/pubmed/22245997. 10.1152/ajplung.00177.2011.
    • (2012) American Journal of Physiology - Lung Cellular and Molecular Physiology , vol.302 , Issue.7 , pp. L651-L663
    • Teng, R.J.1    Du, J.2    Welak, S.3    Guan, T.4    Eis, A.5    Shi, Y.6    Konduri, G.G.7
  • 109
    • 79961102995 scopus 로고    scopus 로고
    • Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis
    • Lee S.J., Kim H.P., Jin Y., Choi A.M., Ryter S.W. Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy 2011, 7(8):829-839. http://www.ncbi.nlm.nih.gov/pubmed/21685724.
    • (2011) Autophagy , vol.7 , Issue.8 , pp. 829-839
    • Lee, S.J.1    Kim, H.P.2    Jin, Y.3    Choi, A.M.4    Ryter, S.W.5
  • 110
    • 84876367698 scopus 로고    scopus 로고
    • Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation
    • Long L., Yang X., Southwood M., Lu J., Marciniak S.J., Dunmore B.J., Morrell N.W. Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation. Circulation Research 2013, 112(8):1159-1170. http://www.ncbi.nlm.nih.gov/pubmed/23446737. 10.1161/CIRCRESAHA.111.300483.
    • (2013) Circulation Research , vol.112 , Issue.8 , pp. 1159-1170
    • Long, L.1    Yang, X.2    Southwood, M.3    Lu, J.4    Marciniak, S.J.5    Dunmore, B.J.6    Morrell, N.W.7
  • 111
    • 84866095437 scopus 로고    scopus 로고
    • LC3 as a potential therapeutic target in hypoxia-induced pulmonary hypertension
    • Lahm T., Petrache I. LC3 as a potential therapeutic target in hypoxia-induced pulmonary hypertension. Autophagy 2012, 8(7):1146-1147. http://www.ncbi.nlm.nih.gov/pubmed/22627195. 10.4161/auto.20520.
    • (2012) Autophagy , vol.8 , Issue.7 , pp. 1146-1147
    • Lahm, T.1    Petrache, I.2
  • 112
    • 84877121075 scopus 로고    scopus 로고
    • MTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects
    • Goncharova E.A. mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects. FASEB Journal 2013, 27(5):1796-1807. http://www.ncbi.nlm.nih.gov/pubmed/23355268. 10.1096/fj.12-222224.
    • (2013) FASEB Journal , vol.27 , Issue.5 , pp. 1796-1807
    • Goncharova, E.A.1
  • 113
    • 84877030807 scopus 로고    scopus 로고
    • Oxidative stress and pulmonary fibrosis
    • Cheresh P., Kim S.J., Tulasiram S., Kamp D.W. Oxidative stress and pulmonary fibrosis. Biochimica et Biophysica Acta 2013, 1832:1028-1040. http://www.ncbi.nlm.nih.gov/pubmed/23219955. 10.1016/j.bbadis.2012.11.021.
    • (2013) Biochimica et Biophysica Acta , vol.1832 , pp. 1028-1040
    • Cheresh, P.1    Kim, S.J.2    Tulasiram, S.3    Kamp, D.W.4
  • 115
    • 84864022325 scopus 로고    scopus 로고
    • Autophagy in idiopathic pulmonary fibrosis
    • Patel A.S., Lin L., Geyer A., Haspel J.A., An C.H., Cao J., Rosas I.O., Morse D. Autophagy in idiopathic pulmonary fibrosis. PLOS One 2012, 7(7):e41394. http://www.ncbi.nlm.nih.gov/pubmed/22815997. 10.1371/journal.pone.0041394.
    • (2012) PLOS One , vol.7 , Issue.7 , pp. e41394
    • Patel, A.S.1    Lin, L.2    Geyer, A.3    Haspel, J.A.4    An, C.H.5    Cao, J.6    Rosas, I.O.7    Morse, D.8
  • 116
    • 80053070208 scopus 로고    scopus 로고
    • Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms
    • Mi S., Li Z., Yang H.Z., Liu H., Wang J.P., Ma Y.G., Wang X.X., Liu H.Z., Sun W., Hu Z.W. Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms. Journal ofImmunology 2011, 187(6):3003-3014. http://www.ncbi.nlm.nih.gov/pubmed/21841134. 10.4049/jimmunol.1004081.
    • (2011) Journal ofImmunology , vol.187 , Issue.6 , pp. 3003-3014
    • Mi, S.1    Li, Z.2    Yang, H.Z.3    Liu, H.4    Wang, J.P.5    Ma, Y.G.6    Wang, X.X.7    Liu, H.Z.8    Sun, W.9    Hu, Z.W.10
  • 118
    • 0035947372 scopus 로고    scopus 로고
    • Impairment of the ubiquitin-proteasome system by protein aggregation
    • Bence N.F., Sampat R.M., Kopito R.R. Impairment of the ubiquitin-proteasome system by protein aggregation. Science 2001, 292(5521):1552-1555. http://www.ncbi.nlm.nih.gov/pubmed/11375494. 10.1126/science.292.5521.1552.
    • (2001) Science , vol.292 , Issue.5521 , pp. 1552-1555
    • Bence, N.F.1    Sampat, R.M.2    Kopito, R.R.3
  • 119
    • 84872735966 scopus 로고    scopus 로고
    • Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells
    • Mayer M.L., Blohmke C.J., Falsafi R., Fjell C.D., Madera L., Turvey S.E., Hancock R.E. Rescue of dysfunctional autophagy attenuates hyperinflammatory responses from cystic fibrosis cells. Journal of Immunology 2013, 190(3):1227-1238. http://www.ncbi.nlm.nih.gov/pubmed/23264659. 10.4049/jimmunol.1201404.
    • (2013) Journal of Immunology , vol.190 , Issue.3 , pp. 1227-1238
    • Mayer, M.L.1    Blohmke, C.J.2    Falsafi, R.3    Fjell, C.D.4    Madera, L.5    Turvey, S.E.6    Hancock, R.E.7
  • 123
    • 84883174355 scopus 로고    scopus 로고
    • Autophagy enhances bacterial clearance during P. aeruginosa lung infection
    • Junkins R.D., Shen A., Rosen K., McCormick C., Lin T.J. Autophagy enhances bacterial clearance during P. aeruginosa lung infection. PLOS One 2013, 8(8):e72263. http://www.ncbi.nlm.nih.gov/pubmed/24015228. 10.1371/journal.pone.0072263.
    • (2013) PLOS One , vol.8 , Issue.8 , pp. e72263
    • Junkins, R.D.1    Shen, A.2    Rosen, K.3    McCormick, C.4    Lin, T.J.5
  • 125
    • 80052941005 scopus 로고    scopus 로고
    • Worldwide behavioral research on major global causes of mortality
    • Dal-Ré R. Worldwide behavioral research on major global causes of mortality. Health Education & Behavior 2011, 38(5):433-440. http://www.ncbi.nlm.nih.gov/pubmed/21558465. 10.1177/1090198111402197.
    • (2011) Health Education & Behavior , vol.38 , Issue.5 , pp. 433-440
    • Dal-Ré, R.1
  • 126
    • 0141928029 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease: molecular and cellular mechanisms
    • Barnes P.J., Shapiro S.D., Pauwels R.A. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. European Respiratory Journal 2003, 22(4):672-688. http://www.ncbi.nlm.nih.gov/pubmed/14582923. 10.1183/09031936.03.00040703.
    • (2003) European Respiratory Journal , vol.22 , Issue.4 , pp. 672-688
    • Barnes, P.J.1    Shapiro, S.D.2    Pauwels, R.A.3
  • 130
    • 53549090696 scopus 로고    scopus 로고
    • Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1
    • Kim H.P., Wang X., Chen Z.H., Lee S.J., Huang M.H., Wang Y., Ryter S.W., Choi A.M. Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy 2008, 4(7):887-895. http://www.ncbi.nlm.nih.gov/pubmed/18769149. 10.4161/auto.6767.
    • (2008) Autophagy , vol.4 , Issue.7 , pp. 887-895
    • Kim, H.P.1    Wang, X.2    Chen, Z.H.3    Lee, S.J.4    Huang, M.H.5    Wang, Y.6    Ryter, S.W.7    Choi, A.M.8
  • 135
    • 84891679916 scopus 로고    scopus 로고
    • Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy
    • Sureshbabu A., Bhandari V. Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy. Frontiers in Physiology 2013, 4:384. http://www.ncbi.nlm.nih.gov/pubmed/24421769. 10.3389/fphys.2013.00384.
    • (2013) Frontiers in Physiology , vol.4 , pp. 384
    • Sureshbabu, A.1    Bhandari, V.2
  • 136
    • 84861526009 scopus 로고    scopus 로고
    • Deconvoluting the context-dependent role for autophagy in cancer
    • White E. Deconvoluting the context-dependent role for autophagy in cancer. Nature Reviews Cancer 2012, 12(6):401-410. http://www.ncbi.nlm.nih.gov/pubmed/22534666. 10.1038/nrc3262.
    • (2012) Nature Reviews Cancer , vol.12 , Issue.6 , pp. 401-410
    • White, E.1
  • 137
    • 85027919042 scopus 로고    scopus 로고
    • The expression of p33(ING1), p53, and autophagy-related gene Beclin1 in patients with non-small cell lung cancer
    • Liu J., Lin Y., Yang H., Deng Q., Chen G., He J. The expression of p33(ING1), p53, and autophagy-related gene Beclin1 in patients with non-small cell lung cancer. Tumor Biology 2011, 32(6):1113-1121. http://www.ncbi.nlm.nih.gov/pubmed/21779982. 10.1007/s13277-011-0211-4.
    • (2011) Tumor Biology , vol.32 , Issue.6 , pp. 1113-1121
    • Liu, J.1    Lin, Y.2    Yang, H.3    Deng, Q.4    Chen, G.5    He, J.6
  • 138
    • 83055194636 scopus 로고    scopus 로고
    • Decreased Beclin-1 expression is correlated with the growth of the primary tumor in patients with squamous cell carcinoma and adenocarcinoma of the lung
    • Won K.Y., Kim G.Y., Lim S.J., Kim Y.W. Decreased Beclin-1 expression is correlated with the growth of the primary tumor in patients with squamous cell carcinoma and adenocarcinoma of the lung. Human Pathology 2012, 43(1):62-68. http://www.ncbi.nlm.nih.gov/pubmed/21777947. 10.1016/j.humpath.2011.04.007.
    • (2012) Human Pathology , vol.43 , Issue.1 , pp. 62-68
    • Won, K.Y.1    Kim, G.Y.2    Lim, S.J.3    Kim, Y.W.4
  • 139
    • 84876219974 scopus 로고    scopus 로고
    • MTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy
    • Kim E.J., Jeong J.H., Bae S., Kang S., Kim C.H., Lim Y.B. mTOR inhibitors radiosensitize PTEN-deficient non-small-cell lung cancer cells harboring an EGFR activating mutation by inducing autophagy. Journal of Cellular Biochemistry 2013, 114(6):1248-1256. http://www.ncbi.nlm.nih.gov/pubmed/23592446. 10.1002/jcb.24465.
    • (2013) Journal of Cellular Biochemistry , vol.114 , Issue.6 , pp. 1248-1256
    • Kim, E.J.1    Jeong, J.H.2    Bae, S.3    Kang, S.4    Kim, C.H.5    Lim, Y.B.6
  • 142
    • 84863714328 scopus 로고    scopus 로고
    • Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy
    • Campbell G.R., Spector S.A. Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy. PLoS Pathogens 2012, 8(5):e1002689. http://www.ncbi.nlm.nih.gov/pubmed/22589721. 10.1371/journal.ppat.1002689.
    • (2012) PLoS Pathogens , vol.8 , Issue.5 , pp. e1002689
    • Campbell, G.R.1    Spector, S.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.