MAP1LC3B overexpression protects against hermansky-pudlak syndrome type-1-induced defective autophagy in vitro

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 310, Issue 6, 2016, Pages L519-L531

  Ahuja, Saket ^a,b   Knudsen, Lars ^c,d,e   Chillappagari, Shashi ^a,b   Henneke, Ingrid ^a,b   Ruppert, Clemens ^a,b,f   Korfei, Martina ^a,b   Gochuico, Bernadette R ^g   Bellusci, Saverio ^a,b,f   Seeger, Werner ^a,b,f,h   Ochs, Matthias ^c,d,e   Guenther, Andreas ^a,b,f,h,i   Mahavadi, Poornima ^a,b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d Member of the German Center for Lung Research   (Germany)

^e Excellence Cluster REBIRTH   (Germany)

^f Department of Cardiac Pathobiology   (Germany)

^g NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^h Member of the European IPF Registry Biobank   (Germany)

ⁱ Lung Clinic Waldhof Elgershausen   (Germany)

Author keywords

Alveolar epithelial cells; Apoptosis; Autophagy; Hermansky Pudlak syndrome; Hermansky Pudlak syndrome associated interstitial pneumonia; Lung fibrosis

Indexed keywords

BAFILOMYCIN A1; CASPASE; CHLOROQUINE; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3BETA; PROTEIN P62; RAPAMYCIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; HPS1 PROTEIN, HUMAN; MAP1LC3B PROTEIN, HUMAN; MEMBRANE PROTEIN;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL STRESS; CONTROLLED STUDY; DRUG EFFICACY; ELECTRON MICROSCOPY; GENE OVEREXPRESSION; HERMANSKY PUDLAK SYNDROME TYPE 1; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LAMELLAR BODY; LUNG; LYSOSOME; MOUSE; NONHUMAN; OCULAR ALBINISM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; TISSUE SECTION; WILD TYPE MOUSE; ANIMAL; C57BL MOUSE; FEMALE; GENETICS; LUNG ALVEOLUS EPITHELIUM CELL; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ALVEOLAR EPITHELIAL CELLS; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; FEMALE; HERMANSKI-PUDLAK SYNDROME; HUMANS; LUNG; MALE; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS;

EID: 84983771928     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00213.2015     Document Type: Article

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