Mitochondrial E3 ubiquitin protein ligase 1 mediates cigarette smoke-induced endothelial cell death and dysfunction

American Journal of Respiratory Cell and Molecular Biology

Volumn 54, Issue 2, 2016, Pages 284-296

  Kim, Sun Yong ^a   Kim, Hyo Jeong ^b   Park, Mi Kyeong ^b   Huh, Jin Won ^c   Park, Hye Yun ^d   Ha, Sang Yun ^e   Shin, Joo Ho ^b   Lee, Yun Song ^b  

^a Ajou University School of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

^d Sungkyunkwan University   (South Korea)

^e Samsung Medical Center   (South Korea)

Author keywords

Akt ubiquitination; Chronic obstructive pulmonary disease; Endothelial cells; Mitochondrial E3 ubiquitin protein ligase 1; Retinoic acid receptor related orphan receptor

Indexed keywords

CIGARETTE SMOKE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MITOCHONDRIAL E3 UBIQUITIN PROTEIN LIGASE 1; PROTEIN KINASE B; RETINOIC ACID RECEPTOR ALPHA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; MITOCHONDRIA-ANCHORED PROTEIN LIGASE, HUMAN; MITOCHONDRIAL E3 UBIQUITIN PROTEIN LIGASE, HUMAN; MITOCHONDRIAL PROTEIN; MUL1 PROTEIN, MOUSE; MUL1 PROTEIN, RAT; NOS3 PROTEIN, HUMAN; NOS3 PROTEIN, RAT; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RORA PROTEIN, HUMAN; RORA PROTEIN, MOUSE; SMOKE; TTC3 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL DEATH; CELL FUNCTION; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LUNG BLOOD VESSEL; LUNG ENDOTHELIUM; REGULATORY MECHANISM; UBIQUITINATION; ADVERSE EFFECTS; ANIMAL; CELL CULTURE; CELL MOTION; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; KNOCKOUT MOUSE; LUNG EMPHYSEMA; METABOLISM; MUTATION; PATHOLOGY; PHOSPHORYLATION; PROTEIN DEGRADATION; RAT; RNA INTERFERENCE; SMOKE; SMOKING; TIME FACTOR; UPREGULATION;

ANIMALS; CELL DEATH; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; MUTATION; NITRIC OXIDE SYNTHASE TYPE III; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1; PHOSPHORYLATION; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY EMPHYSEMA; RATS; RNA INTERFERENCE; SMOKE; SMOKING; TIME FACTORS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; UP-REGULATION;

EID: 84963800531     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2014-0377OC     Document Type: Article

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