-
1
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
DOI 10.1002/path.2277
-
Wynn, T. A. 2008. Cellular and molecular mechanisms of fibrosis. J. Pathol. 214: 199-210. (Pubitemid 351160157)
-
(2008)
Journal of Pathology
, vol.214
, Issue.2
, pp. 199-210
-
-
Wynn, T.A.1
-
2
-
-
67649888821
-
Intestinal fibrosis in IBD - A dynamic, multifactorial process
-
Rieder, F., and C. Fiocchi. 2009. Intestinal fibrosis in IBD - a dynamic, multifactorial process. Nat. Rev. Gastroenterol. Hepatol. 6: 228-235.
-
(2009)
Nat. Rev. Gastroenterol. Hepatol.
, vol.6
, pp. 228-235
-
-
Rieder, F.1
Fiocchi, C.2
-
3
-
-
75949130829
-
Strategies for treating idiopathic pulmonary fibrosis
-
Du Bois, R. M. 2010. Strategies for treating idiopathic pulmonary fibrosis. Nat. Rev. Drug Discov. 9: 129-140.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 129-140
-
-
Du Bois, R.M.1
-
4
-
-
77649275355
-
Extracellular matrix remodeling in atrial fibrosis: Mechanisms and implications in atrial fibrillation
-
Pellman, J., R. C. Lyon, and F. Sheikh. 2010. Extracellular matrix remodeling in atrial fibrosis: mechanisms and implications in atrial fibrillation. J. Mol. Cell. Cardiol. 48: 461-467.
-
(2010)
J. Mol. Cell. Cardiol.
, vol.48
, pp. 461-467
-
-
Pellman, J.1
Lyon, R.C.2
Sheikh, F.3
-
5
-
-
68849090526
-
Idiopathic retroperitoneal fibrosis: A review of the pathogenesis and approaches to treatment
-
Swartz, R. D. 2009. Idiopathic retroperitoneal fibrosis: a review of the pathogenesis and approaches to treatment. Am. J. Kidney Dis. 54: 546-553.
-
(2009)
Am. J. Kidney Dis.
, vol.54
, pp. 546-553
-
-
Swartz, R.D.1
-
6
-
-
27544469550
-
T(H)-17: A giant step from T(H)1 and T(H)2
-
Wynn, T. A. 2005. T(H)-17: a giant step from T(H)1 and T(H)2. Nat. Immunol. 6: 1069-1070.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1069-1070
-
-
Wynn, T.A.1
-
7
-
-
77950365906
-
Nonresolving inflammation
-
Nathan, C., and A. Ding. 2010. Nonresolving inflammation. Cell 140: 871-882.
-
(2010)
Cell
, vol.140
, pp. 871-882
-
-
Nathan, C.1
Ding, A.2
-
8
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
DOI 10.1038/ni1261, PII N1261
-
Park, H., Z. Li, X. O. Yang, S. H. Chang, R. Nurieva, Y. H. Wang, Y. Wang, L. Hood, Z. Zhu, Q. Tian, and C. Dong. 2005. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6: 1133-1141. (Pubitemid 41541791)
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.-H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
9
-
-
59549083038
-
Interleukin-17 as a drug target in human disease
-
Ivanov, S., and A. Lindén. 2009. Interleukin-17 as a drug target in human disease. Trends Pharmacol. Sci. 30: 95-103.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 95-103
-
-
Ivanov, S.1
Lindén, A.2
-
10
-
-
77956899738
-
Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model
-
Yoshizaki, A., K. Yanaba, Y. Iwata, K. Komura, A. Ogawa, Y. Akiyama, E. Muroi, T. Hara, F. Ogawa, M. Takenaka, et al. 2010. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J. Immunol. 185: 2502-2515.
-
(2010)
J. Immunol.
, vol.185
, pp. 2502-2515
-
-
Yoshizaki, A.1
Yanaba, K.2
Iwata, Y.3
Komura, K.4
Ogawa, A.5
Akiyama, Y.6
Muroi, E.7
Hara, T.8
Ogawa, F.9
Takenaka, M.10
-
11
-
-
77953021137
-
Interleukin-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy
-
Baldeviano, G. C., J. G. Barin, M. V. Talor, S. Srinivasan, D. Bedja, D. Zheng, K. Gabrielson, Y. Iwakura, N. R. Rose, and D. Cihakova. 2010. Interleukin-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy. Circ. Res. 106: 1646-1655.
-
(2010)
Circ. Res.
, vol.106
, pp. 1646-1655
-
-
Baldeviano, G.C.1
Barin, J.G.2
Talor, M.V.3
Srinivasan, S.4
Bedja, D.5
Zheng, D.6
Gabrielson, K.7
Iwakura, Y.8
Rose, N.R.9
Cihakova, D.10
-
12
-
-
77951485998
-
Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice
-
Smith, E., K. M. Prasad, M. Butcher, A. Dobrian, J. K. Kolls, K. Ley, and E. Galkina. 2010. Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice. Circulation 121: 1746-1755.
-
(2010)
Circulation
, vol.121
, pp. 1746-1755
-
-
Smith, E.1
Prasad, K.M.2
Butcher, M.3
Dobrian, A.4
Kolls, J.K.5
Ley, K.6
Galkina, E.7
-
13
-
-
77949516122
-
Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent
-
Wilson, M. S., S. K. Madala, T. R. Ramalingam, B. R. Gochuico, I. O. Rosas, A. W. Cheever, and T. A. Wynn. 2010. Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent. J. Exp. Med. 207: 535-552.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 535-552
-
-
Wilson, M.S.1
Madala, S.K.2
Ramalingam, T.R.3
Gochuico, B.R.4
Rosas, I.O.5
Cheever, A.W.6
Wynn, T.A.7
-
14
-
-
68349130145
-
Blocking TLR2 activity attenuates pulmonary metastases of tumor
-
Yang, H. Z., B. Cui, H. Z. Liu, S. Mi, J. Yan, H. M. Yan, F. Hua, H. Lin, W. F. Cai, W. J. Xie, et al. 2009. Blocking TLR2 activity attenuates pulmonary metastases of tumor. PLoS ONE 4: e6520.
-
(2009)
PLoS ONE
, vol.4
-
-
Yang, H.Z.1
Cui, B.2
Liu, H.Z.3
Mi, S.4
Yan, J.5
Yan, H.M.6
Hua, F.7
Lin, H.8
Cai, W.F.9
Xie, W.J.10
-
15
-
-
59849084848
-
Targeting TLR2 attenuates pulmonary inflammation and fibrosis by reversion of suppressive immune microenvironment
-
Yang, H. Z., B. Cui, H. Z. Liu, Z. R. Chen, H. M. Yan, F. Hua, and Z. W. Hu. 2009. Targeting TLR2 attenuates pulmonary inflammation and fibrosis by reversion of suppressive immune microenvironment. J. Immunol. 182: 692-702.
-
(2009)
J. Immunol.
, vol.182
, pp. 692-702
-
-
Yang, H.Z.1
Cui, B.2
Liu, H.Z.3
Chen, Z.R.4
Yan, H.M.5
Hua, F.6
Hu, Z.W.7
-
16
-
-
33644550621
-
Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo
-
Knapp, S., S. Florquin, D. T. Golenbock, and T. Van der Poll. 2006. Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo. J. Immunol. 176: 3189-3195.
-
(2006)
J. Immunol.
, vol.176
, pp. 3189-3195
-
-
Knapp, S.1
Florquin, S.2
Golenbock, D.T.3
Van Der Poll, T.4
-
17
-
-
72849117761
-
Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages
-
Atabai, K., S. Jame, N. Azhar, A. Kuo, M. Lam, W. McKleroy, G. Dehart, S. Rahman, D. D. Xia, A. C. Melton, et al. 2009. Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages. J. Clin. Invest. 119: 3713-3722.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3713-3722
-
-
Atabai, K.1
Jame, S.2
Azhar, N.3
Kuo, A.4
Lam, M.5
McKleroy, W.6
Dehart, G.7
Rahman, S.8
Xia, D.D.9
Melton, A.C.10
-
18
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
Salazar, M., A. Carracedo, I. J. Salanueva, S. Hernández-Tiedra, M. Lorente, A. Egia, P. Vázquez, C. Blázquez, S. Torres, S. Garc?́a, et al. 2009. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J. Clin. Invest. 119: 1359-1372.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernández-Tiedra, S.4
Lorente, M.5
Egia, A.6
Vázquez, P.7
Blázquez, C.8
Torres, S.9
Garća, S.10
-
19
-
-
33845511362
-
Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy
-
DOI 10.1038/sj.cdd.4401936, PII 4401936
-
Hamacher-Brady, A., N. R. Brady, S. E. Logue, M. R. Sayen, M. Jinno, L. A. Kirshenbaum, R. A. Gottlieb, and A. B. Gustafsson. 2007. Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy. Cell Death Differ. 14: 146-157. (Pubitemid 44911902)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.1
, pp. 146-157
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Logue, S.E.3
Sayen, M.R.4
Jinno, M.5
Kirshenbaum, L.A.6
Gottlieb, R.A.7
Gustafsson, A.B.8
-
20
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery, J. P., H. Acloque, R. Y. Huang, and M. A. Nieto. 2009. Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
21
-
-
33847206969
-
IL-17 family cytokines and the expanding diversity of effector T cell lineages
-
DOI 10.1146/annurev.immunol.25.022106.141557
-
Weaver, C. T., R. D. Hatton, P. R. Mangan, and L. E. Harrington. 2007. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821-852. (Pubitemid 46697925)
-
(2007)
Annual Review of Immunology
, vol.25
, pp. 821-852
-
-
Weaver, C.T.1
Hatton, R.D.2
Mangan, P.R.3
Harrington, L.E.4
-
22
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu, J., S. Lamouille, and R. Derynck. 2009. TGF-beta-induced epithelial to mesenchymal transition. Cell Res. 19: 156-172.
-
(2009)
Cell Res.
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
23
-
-
59849114998
-
RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F
-
Leppkes, M., C. Becker, I. I. Ivanov, S. Hirth, S. Wirtz, C. Neufert, S. Pouly, A. J. Murphy, D. M. Valenzuela, G. D. Yancopoulos, et al. 2009. RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. Gastroenterology 136: 257-267.
-
(2009)
Gastroenterology
, vol.136
, pp. 257-267
-
-
Leppkes, M.1
Becker, C.2
Ivanov, I.I.3
Hirth, S.4
Wirtz, S.5
Neufert, C.6
Pouly, S.7
Murphy, A.J.8
Valenzuela, D.M.9
Yancopoulos, G.D.10
-
24
-
-
77950366886
-
Decoding cell death signals in inflammation and immunity
-
Zitvogel, L., O. Kepp, and G. Kroemer. 2010. Decoding cell death signals in inflammation and immunity. Cell 140: 798-804.
-
(2010)
Cell
, vol.140
, pp. 798-804
-
-
Zitvogel, L.1
Kepp, O.2
Kroemer, G.3
-
25
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima, N., T. Yoshimori, and B. Levine. 2010. Methods in mammalian autophagy research. Cell 140: 313-326.
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
26
-
-
77953543377
-
The Beclin 1-VPS34 complex - At the crossroads of autophagy and beyond
-
Funderburk, S. F., Q. J. Wang, and Z. Yue. 2010. The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol. 20: 355-362.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
27
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
Mathew, R., C. M. Karp, B. Beaudoin, N. Vuong, G. Chen, H. Y. Chen, K. Bray, A. Reddy, G. Bhanot, C. Gelinas, et al. 2009. Autophagy suppresses tumorigenesis through elimination of p62. Cell 137: 1062-1075.
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
Chen, H.Y.6
Bray, K.7
Reddy, A.8
Bhanot, G.9
Gelinas, C.10
-
28
-
-
56749170677
-
Autophagic cell death: The story of a misnomer
-
Kroemer, G., and B. Levine. 2008. Autophagic cell death: the story of a misnomer. Nat. Rev. Mol. Cell Biol. 9: 1004-1010.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
29
-
-
77953792923
-
Mediatory molecules that fuse autophagosomes and lysosomes
-
Furuta, N., T. Yoshimori, and A. Amano. 2010. Mediatory molecules that fuse autophagosomes and lysosomes. Autophagy 6: 417-418.
-
(2010)
Autophagy
, vol.6
, pp. 417-418
-
-
Furuta, N.1
Yoshimori, T.2
Amano, A.3
-
30
-
-
73949125596
-
Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle
-
Aitken, K. J., C. Tolg, T. Panchal, B. Leslie, J. Yu, M. Elkelini, N. Sabha, D. J. Tse, A. J. Lorenzo, M. Hassouna, and D. J. Bägli. 2010. Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle. Am. J. Pathol. 176: 304-319.
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 304-319
-
-
Aitken, K.J.1
Tolg, C.2
Panchal, T.3
Leslie, B.4
Yu, J.5
Elkelini, M.6
Sabha, N.7
Tse, D.J.8
Lorenzo, A.J.9
Hassouna, M.10
Bägli, D.J.11
-
31
-
-
47249145558
-
Bacillus Calmette-Guérin and TLR4 agonist prevent cardiovascular hypertrophy and fibrosis by regulating immune microenvironment
-
Liu, Y. Y., W. F. Cai, H. Z. Yang, B. Cui, Z. R. Chen, H. Z. Liu, J. Yan, W. Jin, H. M. Yan, B. M. Xin, et al. 2008. Bacillus Calmette-Guérin and TLR4 agonist prevent cardiovascular hypertrophy and fibrosis by regulating immune microenvironment. J. Immunol. 180: 7349-7357.
-
(2008)
J. Immunol.
, vol.180
, pp. 7349-7357
-
-
Liu, Y.Y.1
Cai, W.F.2
Yang, H.Z.3
Cui, B.4
Chen, Z.R.5
Liu, H.Z.6
Yan, J.7
Jin, W.8
Yan, H.M.9
Xin, B.M.10
-
32
-
-
34548700401
-
T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis
-
DOI 10.1016/j.immuni.2007.07.022, PII S1074761307004177
-
Harris, J., S. A. De Haro, S. S. Master, J. Keane, E. A. Roberts, M. Delgado, and V. Deretic. 2007. T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. Immunity 27: 505-517. (Pubitemid 47418681)
-
(2007)
Immunity
, vol.27
, Issue.3
, pp. 505-517
-
-
Harris, J.1
De Haro, S.A.2
Master, S.S.3
Keane, J.4
Roberts, E.A.5
Delgado, M.6
Deretic, V.7
-
33
-
-
79955701910
-
Scraping fibrosis: Expressway to the core of fibrosis
-
Mehal, W. Z., J. Iredale, and S. L. Friedman. 2011. Scraping fibrosis: expressway to the core of fibrosis. Nat. Med. 17: 552-553.
-
(2011)
Nat. Med.
, vol.17
, pp. 552-553
-
-
Mehal, W.Z.1
Iredale, J.2
Friedman, S.L.3
-
34
-
-
71549124671
-
Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells
-
Kiyono, K., H. I. Suzuki, H. Matsuyama, Y. Morishita, A. Komuro, M. R. Kano, K. Sugimoto, and K. Miyazono. 2009. Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells. Cancer Res. 69: 8844-8852.
-
(2009)
Cancer Res.
, vol.69
, pp. 8844-8852
-
-
Kiyono, K.1
Suzuki, H.I.2
Matsuyama, H.3
Morishita, Y.4
Komuro, A.5
Kano, M.R.6
Sugimoto, K.7
Miyazono, K.8
-
35
-
-
77957252460
-
Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
-
Koesters, R., B. Kaissling, M. Lehir, N. Picard, F. Theilig, R. Gebhardt, A. B. Glick, B. Hähnel, H. Hosser, H. J. Gröne, and W. Kriz. 2010. Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am. J. Pathol. 177: 632-643.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 632-643
-
-
Koesters, R.1
Kaissling, B.2
Lehir, M.3
Picard, N.4
Theilig, F.5
Gebhardt, R.6
Glick, A.B.7
Hähnel, B.8
Hosser, H.9
Gröne, H.J.10
Kriz, W.11
-
36
-
-
80053091021
-
Characterisation of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells
-
Buckley, S., C. Medina, and C. Ehrhardt. 2009. Characterisation of the role of inflammatory cytokines in EMT and cell migration in alveolar epithelial cells. Am. J. Respir. Crit. Care Med. 179: A5298.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
-
-
Buckley, S.1
Medina, C.2
Ehrhardt, C.3
-
37
-
-
74949108768
-
IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemiareperfusion injury
-
Li, L., L. Huang, A. L. Vergis, H. Ye, A. Bajwa, V. Narayan, R. M. Strieter, D. L. Rosin, and M. D. Okusa. 2010. IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemiareperfusion injury. J. Clin. Invest. 120: 331-342.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 331-342
-
-
Li, L.1
Huang, L.2
Vergis, A.L.3
Ye, H.4
Bajwa, A.5
Narayan, V.6
Strieter, R.M.7
Rosin, D.L.8
Okusa, M.D.9
-
38
-
-
77949314815
-
IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis
-
Doodes, P. D., Y. Cao, K. M. Hamel, Y. Wang, R. L. Rodeghero, K. Mikecz, T. T. Glant, Y. Iwakura, and A. Finnegan. 2010. IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis. J. Immunol. 184: 1552-1559
-
(2010)
J. Immunol.
, vol.184
, pp. 1552-1559
-
-
Doodes, P.D.1
Cao, Y.2
Hamel, K.M.3
Wang, Y.4
Rodeghero, R.L.5
Mikecz, K.6
Glant, T.T.7
Iwakura, Y.8
Finnegan, A.9
|