-
1
-
-
34249742714
-
Chronic obstructive pulmonary disease: A growing but neglected global epidemic
-
Barnes PJ. Chronic obstructive pulmonary disease: a growing but neglected global epidemic. PLoS Med 2007;4:e112.
-
(2007)
PLoS Med
, vol.4
, pp. e112
-
-
Barnes, P.J.1
-
2
-
-
34447556991
-
Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease
-
Yoshida T, Tuder RM. Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol Rev 2007;87: 1047-1082.
-
(2007)
Physiol Rev
, vol.87
, pp. 1047-1082
-
-
Yoshida, T.1
Tuder, R.M.2
-
3
-
-
31844435204
-
Chronic obstructive pulmonary disease: Current burden and future projections
-
Lopez AD, Shibuya K, Rao C, Mathers CD, Hansell AL, Held LS, Schmid V, Buist S. Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J 2006;27:397-412.
-
(2006)
Eur Respir J
, vol.27
, pp. 397-412
-
-
Lopez, A.D.1
Shibuya, K.2
Rao, C.3
Mathers, C.D.4
Hansell, A.L.5
Held, L.S.6
Schmid, V.7
Buist, S.8
-
4
-
-
58249099942
-
COPD as a disease of accelerated lung aging
-
Ito K, Barnes PJ. COPD as a disease of accelerated lung aging. Chest 2009;135:173-180.
-
(2009)
Chest
, vol.135
, pp. 173-180
-
-
Ito, K.1
Barnes, P.J.2
-
5
-
-
33750620057
-
Oxidative stress and redox regulation of lung inflammation in COPD
-
Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J 2006;28:219-242.
-
(2006)
Eur Respir J
, vol.28
, pp. 219-242
-
-
Rahman, I.1
Adcock, I.M.2
-
6
-
-
33644643244
-
Elastin fragments drive disease progression in a murine model of emphysema
-
Houghton AM, Quintero PA, Perkins DL, Kobayashi DK, Kelley DG, Marconcini LA, Mecham RP, Senior RM, Shapiro SD. Elastin fragments drive disease progression in a murine model of emphysema. J Clin Invest 2006;116:753-759.
-
(2006)
J Clin Invest
, vol.116
, pp. 753-759
-
-
Houghton, A.M.1
Quintero, P.A.2
Perkins, D.L.3
Kobayashi, D.K.4
Kelley, D.G.5
Marconcini, L.A.6
Mecham, R.P.7
Senior, R.M.8
Shapiro, S.D.9
-
7
-
-
84883771053
-
Tobacco smoke induced COPD/emphysema in the animal model: Are we all on the same page?
-
Leberl M, Kratzer A, Taraseviciene-Stewart L. Tobacco smoke induced COPD/emphysema in the animal model: are we all on the same page? Front Physiol 2013;4:91.
-
(2013)
Front Physiol
, vol.4
, pp. 91
-
-
Leberl, M.1
Kratzer, A.2
Taraseviciene-Stewart, L.3
-
9
-
-
80053545029
-
The effect of secondhand smoke exposure on markers of elastin degradation
-
Slowik N, Ma S, He J, Lin YY, Soldin OP, Robbins RA, Turino GM. The effect of secondhand smoke exposure on markers of elastin degradation. Chest 2011;140:946-953.
-
(2011)
Chest
, vol.140
, pp. 946-953
-
-
Slowik, N.1
Ma, S.2
He, J.3
Lin, Y.Y.4
Soldin, O.P.5
Robbins, R.A.6
Turino, G.M.7
-
10
-
-
79151479184
-
Worldwide burden of disease from exposure to second-hand smoke: A retrospective analysis of data from 192 countries
-
Oberg M, Jaakkola MS, Woodward A, Peruga A, Pruss-Ustun A. Worldwide burden of disease from exposure to second-hand smoke: a retrospective analysis of data from 192 countries. Lancet 2011;377: 139-146.
-
(2011)
Lancet
, vol.377
, pp. 139-146
-
-
Oberg, M.1
Jaakkola, M.S.2
Woodward, A.3
Peruga, A.4
Pruss-Ustun, A.5
-
11
-
-
84871916713
-
Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease
-
Fujii S, Hara H, Araya J, Takasaka N, Kojima J, Ito S, Minagawa S, Yumino Y, Ishikawa T, Numata T, et al. Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease. OncoImmunology 2012;1: 630-641.
-
(2012)
OncoImmunology
, vol.1
, pp. 630-641
-
-
Fujii, S.1
Hara, H.2
Araya, J.3
Takasaka, N.4
Kojima, J.5
Ito, S.6
Minagawa, S.7
Yumino, Y.8
Ishikawa, T.9
Numata, T.10
-
13
-
-
78649754758
-
Early-age-related changes in proteostasis augment immunopathogenesis of sepsis and acute lung injury
-
Bodas M, Min T, Vij N. Early-age-related changes in proteostasis augment immunopathogenesis of sepsis and acute lung injury. PLoS One 2010;5:e15480.
-
(2010)
PLoS One
, vol.5
, pp. e15480
-
-
Bodas, M.1
Min, T.2
Vij, N.3
-
14
-
-
79960013933
-
Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema
-
Min T, Bodas M, Mazur S, Vij N. Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema. J Mol Med (Berl) 2011;89: 577-593.
-
(2011)
J Mol Med (Berl)
, vol.89
, pp. 577-593
-
-
Min, T.1
Bodas, M.2
Mazur, S.3
Vij, N.4
-
15
-
-
84863506784
-
Therapeutic strategies to correct proteostasis-imbalance in chronic obstructive lung diseases
-
Bodas M, Tran I, Vij N. Therapeutic strategies to correct proteostasis-imbalance in chronic obstructive lung diseases. Curr Mol Med 2012; 12:807-814.
-
(2012)
Curr Mol Med
, vol.12
, pp. 807-814
-
-
Bodas, M.1
Tran, I.2
Vij, N.3
-
16
-
-
84880079298
-
Oxidative stress in COPD
-
Kirkham PA, Barnes PJ. Oxidative stress in COPD. Chest 2013;144:266-273.
-
(2013)
Chest
, vol.144
, pp. 266-273
-
-
Kirkham, P.A.1
Barnes, P.J.2
-
17
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell 2013;153:1194-1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
18
-
-
84890229110
-
Create and preserve: Proteostasis in development and aging is governed by Cdc48/p97/VCP
-
Franz A, Ackermann L, Hoppe T. Create and preserve: proteostasis in development and aging is governed by Cdc48/p97/VCP. Biochim Biophys Acta 2014;1843:205-215.
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 205-215
-
-
Franz, A.1
Ackermann, L.2
Hoppe, T.3
-
19
-
-
70349266064
-
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
-
Ben-Zvi A, Miller EA, Morimoto RI. Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc Natl Acad Sci USA 2009;106:14914-14919.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14914-14919
-
-
Ben-Zvi, A.1
Miller, E.A.2
Morimoto, R.I.3
-
20
-
-
84864319448
-
Age-related oxidative stress compromises endosomal proteostasis
-
Cannizzo ES, Clement CC, Morozova K, Valdor R, Kaushik S, Almeida LN, Follo C, Sahu R, Cuervo AM, Macian F, Santambrogio L. Age-related oxidative stress compromises endosomal proteostasis. Cell Rep 2012;2:136-149.
-
(2012)
Cell Rep
, vol.2
, pp. 136-149
-
-
Cannizzo, E.S.1
Clement, C.C.2
Morozova, K.3
Valdor, R.4
Kaushik, S.5
Almeida, L.N.6
Follo, C.7
Sahu, R.8
Cuervo, A.M.9
Macian, F.10
Santambrogio, L.11
-
21
-
-
72549115279
-
Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: The role of Nrf2-regulated proteasomal activity
-
Malhotra D, Thimmulappa R, Vij N, Navas-Acien A, Sussan T, Merali S, Zhang L, Kelsen SG, Myers A, Wise R, et al. Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. Am J Respir Crit Care Med 2009;180:1196-1207.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 1196-1207
-
-
Malhotra, D.1
Thimmulappa, R.2
Vij, N.3
Navas-Acien, A.4
Sussan, T.5
Merali, S.6
Zhang, L.7
Kelsen, S.G.8
Myers, A.9
Wise, R.10
-
22
-
-
84868358100
-
Acute cigarette smoke exposure impairs proteasome function in the lung
-
van Rijt SH, Keller IE, John G, Kohse K, Yildirim AO, Eickelberg O, Meiners S. Acute cigarette smoke exposure impairs proteasome function in the lung. Am J Physiol Lung Cell Mol Physiol 2012;303: L814-L823.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.303
, pp. L814-L823
-
-
Van Rijt, S.H.1
Keller, I.E.2
John, G.3
Kohse, K.4
Yildirim, A.O.5
Eickelberg, O.6
Meiners, S.7
-
23
-
-
0032576605
-
Aggresomes: A cellular response to misfolded proteins
-
Johnston JA, Ward CL, Kopito RR. Aggresomes: a cellular response to misfolded proteins. J Cell Biol 1998;143:1883-1898.
-
(1998)
J Cell Biol
, vol.143
, pp. 1883-1898
-
-
Johnston, J.A.1
Ward, C.L.2
Kopito, R.R.3
-
24
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito RR. Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 2000;10:524-530.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
25
-
-
84980052506
-
Protein aggregation and degradation mechanisms in neurodegenerative diseases
-
Takalo M, Salminen A, Soininen H, Hiltunen M, Haapasalo A. Protein aggregation and degradation mechanisms in neurodegenerative diseases. Am J Neurodegener Dis 2013;2:1-14.
-
(2013)
Am J Neurodegener Dis
, vol.2
, pp. 1-14
-
-
Takalo, M.1
Salminen, A.2
Soininen, H.3
Hiltunen, M.4
Haapasalo, A.5
-
26
-
-
84878431591
-
The activation sequence of cellular protein handling systems after proteasomal inhibition in dopaminergic cells
-
Xiong R, Siegel D, Ross D. The activation sequence of cellular protein handling systems after proteasomal inhibition in dopaminergic cells. Chem Biol Interact 2013;204:116-124.
-
(2013)
Chem Biol Interact
, vol.204
, pp. 116-124
-
-
Xiong, R.1
Siegel, D.2
Ross, D.3
-
27
-
-
78349276861
-
Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes
-
Janen SB, Chaachouay H, Richter-Landsberg C. Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes. Glia 2010;58:1766-1774.
-
(2010)
Glia
, vol.58
, pp. 1766-1774
-
-
Janen, S.B.1
Chaachouay, H.2
Richter-Landsberg, C.3
-
28
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004;6: 463-477.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
29
-
-
33746108329
-
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
-
Tanida I, Minematsu-Ikeguchi N, Ueno T, Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 2005;1:84-91.
-
(2005)
Autophagy
, vol.1
, pp. 84-91
-
-
Tanida, I.1
Minematsu-Ikeguchi, N.2
Ueno, T.3
Kominami, E.4
-
30
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Overvatn A, Bjorkoy G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007;282: 24131-24145.
-
(2007)
J Biol Chem
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
32
-
-
79953657006
-
Deadly triplex: Smoke, autophagy and apoptosis
-
Ryter SW, Lam HC, Chen ZH, Choi AM. Deadly triplex: smoke, autophagy and apoptosis. Autophagy 2011;7:436-437.
-
(2011)
Autophagy
, vol.7
, pp. 436-437
-
-
Ryter, S.W.1
Lam, H.C.2
Zh, C.3
Choi, A.M.4
-
33
-
-
84872191992
-
Cigarette smoke induces endoplasmic reticulum stress response and proteasomal dysfunction in human alveolar epithelial cells
-
Somborac-Bacura A, van der Toorn M, Franciosi L, Slebos DJ, Zanic-Grubisic T, Bischoff R, van Oosterhout AJ. Cigarette smoke induces endoplasmic reticulum stress response and proteasomal dysfunction in human alveolar epithelial cells. Exp Physiol 2013;98: 316-325.
-
(2013)
Exp Physiol
, vol.98
, pp. 316-325
-
-
Somborac-Bacura, A.1
Van Der Toorn, M.2
Franciosi, L.3
Slebos, D.J.4
Zanic-Grubisic, T.5
Bischoff, R.6
Van Oosterhout, A.J.7
-
34
-
-
45849117920
-
Second-hand smoke and human lung cancer
-
Besaratinia A, Pfeifer GP. Second-hand smoke and human lung cancer. Lancet Oncol 2008;9:657-666.
-
(2008)
Lancet Oncol
, vol.9
, pp. 657-666
-
-
Besaratinia, A.1
Pfeifer, G.P.2
-
35
-
-
0032209539
-
Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells
-
Su Y, Han W, Giraldo C, De Li Y, Block ER. Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells. Am J Respir Cell Mol Biol 1998;19:819-825.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 819-825
-
-
Su, Y.1
Han, W.2
Giraldo, C.3
De Li, Y.4
Block, E.R.5
-
36
-
-
33750949369
-
Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells
-
Kode A, Yang SR, Rahman I. Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells. Respir Res 2006;7:132.
-
(2006)
Respir Res
, vol.7
, pp. 132
-
-
Kode, A.1
Yang, S.R.2
Rahman, I.3
-
37
-
-
34547198361
-
P38 mitogen-activated protein kinase mediates sidestream cigarette smoke-induced endothelial permeability
-
Low B, Liang M, Fu J. p38 mitogen-activated protein kinase mediates sidestream cigarette smoke-induced endothelial permeability. J Pharmacol Sci 2007;104:225-231.
-
(2007)
J Pharmacol Sci
, vol.104
, pp. 225-231
-
-
Low, B.1
Liang, M.2
Fu, J.3
-
38
-
-
0036580648
-
Effects of cigarette smoke on the immune system
-
Sopori M. Effects of cigarette smoke on the immune system. Nat Rev Immunol 2002;2:372-377.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 372-377
-
-
Sopori, M.1
-
39
-
-
79251588056
-
Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema
-
Bodas M, Min T, Mazur S, Vij N. Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema. J Immunol 2011;186:602-613.
-
(2011)
J Immunol
, vol.186
, pp. 602-613
-
-
Bodas, M.1
Min, T.2
Mazur, S.3
Vij, N.4
-
40
-
-
84055172732
-
Critical role of VCP/p97 in the pathogenesis and progression of non-small cell lung carcinoma
-
Valle CW, Min T, Bodas M, Mazur S, Begum S, Tang D, Vij N. Critical role of VCP/p97 in the pathogenesis and progression of non-small cell lung carcinoma. PLoS One 2011;6:e29073.
-
(2011)
PLoS One
, vol.6
, pp. e29073
-
-
Valle, C.W.1
Min, T.2
Bodas, M.3
Mazur, S.4
Begum, S.5
Tang, D.6
Vij, N.7
-
41
-
-
1642421036
-
Lumican suppresses cell proliferation and AIDS Fas-Fas ligand mediated apoptosis: Implications in the cornea
-
Vij N, Roberts L, Joyce S, Chakravarti S. Lumican suppresses cell proliferation and aids Fas-Fas ligand mediated apoptosis: implications in the cornea. Exp Eye Res 2004;78:957-971.
-
(2004)
Exp Eye Res
, vol.78
, pp. 957-971
-
-
Vij, N.1
Roberts, L.2
Joyce, S.3
Chakravarti, S.4
-
42
-
-
0029651761
-
Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy: UK Lamotrigine/Carbamazepine Monotherapy Trial Group
-
Brodie MJ, Richens A, Yuen AW. Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy: UK Lamotrigine/Carbamazepine Monotherapy Trial Group. Lancet 1995; 345:476-479.
-
(1995)
Lancet
, vol.345
, pp. 476-479
-
-
Brodie, M.J.1
Richens, A.2
Yuen, A.W.3
-
43
-
-
0030666691
-
Comparative prophylactic efficacy of lithium, carbamazepine, and the combination in bipolar disorder
-
Denicoff KD, Smith-Jackson EE, Disney ER, Ali SO, Leverich GS, Post RM. Comparative prophylactic efficacy of lithium, carbamazepine, and the combination in bipolar disorder. J Clin Psychiatry 1997;58: 470-478.
-
(1997)
J Clin Psychiatry
, vol.58
, pp. 470-478
-
-
Denicoff, K.D.1
Smith-Jackson, E.E.2
Disney, E.R.3
Ali, S.O.4
Leverich, G.S.5
Post, R.M.6
-
44
-
-
84863677794
-
Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy
-
Shi J, Yin N, Xuan LL, Yao CS, Meng AM, Hou Q. Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy. Acta Pharmacol Sin 2012;33:888-896.
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 888-896
-
-
Shi, J.1
Yin, N.2
Xuan, L.L.3
Yao, C.S.4
Meng, A.M.5
Hou, Q.6
-
45
-
-
77954597127
-
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
-
Hidvegi T, Ewing M, Hale P, Dippold C, Beckett C, Kemp C, Maurice N, Mukherjee A, Goldbach C, Watkins S, et al. An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis. Science 2010;329:229-232.
-
(2010)
Science
, vol.329
, pp. 229-232
-
-
Hidvegi, T.1
Ewing, M.2
Hale, P.3
Dippold, C.4
Beckett, C.5
Kemp, C.6
Maurice, N.7
Mukherjee, A.8
Goldbach, C.9
Watkins, S.10
-
46
-
-
0034907973
-
Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation
-
Dai RM, Li CC. Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation. Nat Cell Biol 2001;3:740-744.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 740-744
-
-
Dai, R.M.1
Li, C.C.2
-
47
-
-
18544394748
-
RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis
-
Wojcik C, Yano M, DeMartino GN. RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis. J Cell Sci 2004;117: 281-292.
-
(2004)
J Cell Sci
, vol.117
, pp. 281-292
-
-
Wojcik, C.1
Yano, M.2
DeMartino, G.N.3
-
48
-
-
41949092173
-
The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation
-
Song C, Xiao Z, Nagashima K, Li CC, Lockett SJ, Dai RM, Cho EH, Conrads TP, Veenstra TD, Colburn NH, et al. The heavy metal cadmium induces valosin-containing protein (VCP)-mediated aggresome formation. Toxicol Appl Pharmacol 2008;228:351-363.
-
(2008)
Toxicol Appl Pharmacol
, vol.228
, pp. 351-363
-
-
Song, C.1
Xiao, Z.2
Nagashima, K.3
Li, C.C.4
Lockett, S.J.5
Dai, R.M.6
Cho, E.H.7
Conrads, T.P.8
Veenstra, T.D.9
Colburn, N.H.10
-
49
-
-
34250735508
-
Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates
-
Kobayashi T, Manno A, Kakizuka A. Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates. Genes Cells 2007;12:889-901.
-
(2007)
Genes Cells
, vol.12
, pp. 889-901
-
-
Kobayashi, T.1
Manno, A.2
Kakizuka, A.3
-
50
-
-
33645926989
-
P62/SQSTM1: A missing link between protein aggregates and the autophagy machinery
-
Bjorkoy G, Lamark T, Johansen T. p62/SQSTM1: a missing link between protein aggregates and the autophagy machinery. Autophagy 2006;2:138-139.
-
(2006)
Autophagy
, vol.2
, pp. 138-139
-
-
Bjorkoy, G.1
Lamark, T.2
Johansen, T.3
-
51
-
-
79958198426
-
Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury
-
Bodas M, Min T, Vij N. Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury. Am J Physiol Lung Cell Mol Physiol 2011;300:L811-L820.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, pp. L811-L820
-
-
Bodas, M.1
Min, T.2
Vij, N.3
-
52
-
-
78149476302
-
Identification of an autophagy defect in smokers' alveolar macrophages
-
Monick MM, Powers LS, Walters K, Lovan N, Zhang M, Gerke A, Hansdottir S, Hunninghake GW. Identification of an autophagy defect in smokers' alveolar macrophages. J Immunol 2010;185: 5425-5435.
-
(2010)
J Immunol
, vol.185
, pp. 5425-5435
-
-
Monick, M.M.1
Powers, L.S.2
Walters, K.3
Lovan, N.4
Zhang, M.5
Gerke, A.6
Hansdottir, S.7
Hunninghake, G.W.8
-
53
-
-
22144445316
-
Diaphragm dysfunction in chronic obstructive pulmonary disease
-
Ottenheijm CA, Heunks LM, Sieck GC, Zhan WZ, Jansen SM, Degens H, de Boo T, Dekhuijzen PN. Diaphragm dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2005; 172:200-205.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 200-205
-
-
Ottenheijm, C.A.1
Heunks, L.M.2
Sieck, G.C.3
Zhan, W.Z.4
Jansen, S.M.5
Degens, H.6
De Boo, T.7
Dekhuijzen, P.N.8
-
54
-
-
33750600130
-
Activation of the ubiquitin-proteasome pathway in the diaphragm in chronic obstructive pulmonary disease
-
Ottenheijm CA, Heunks LM, Li YP, Jin B, Minnaard R, van Hees HW, Dekhuijzen PN. Activation of the ubiquitin-proteasome pathway in the diaphragm in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2006;174:997-1002.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 997-1002
-
-
Ottenheijm, C.A.1
Heunks, L.M.2
Li, Y.P.3
Jin, B.4
Minnaard, R.5
Van Hees, H.W.6
Dekhuijzen, P.N.7
-
55
-
-
38049014824
-
Parkin-mediated K63-linked polyubiquitination: A signal for targeting misfolded proteins to the aggresome-autophagy pathway
-
Olzmann JA, Chin LS. Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway. Autophagy 2008;4:85-87.
-
(2008)
Autophagy
, vol.4
, pp. 85-87
-
-
Olzmann, J.A.1
Chin, L.S.2
-
56
-
-
0036303981
-
Hassles with taking out the garbage: Aggravating aggresomes
-
Garcia-Mata R, Gao YS, Sztul E. Hassles with taking out the garbage: aggravating aggresomes. Traffic 2002;3:388-396.
-
(2002)
Traffic
, vol.3
, pp. 388-396
-
-
Garcia-Mata, R.1
Gao, Y.S.2
Sztul, E.3
-
57
-
-
84903820951
-
Autophagy: An integral component of the mammalian stress response
-
Ryter SW, Choi AM. Autophagy: an integral component of the mammalian stress response. J Biochem Pharmacol Res 2013;1:176-188.
-
(2013)
J Biochem Pharmacol Res
, vol.1
, pp. 176-188
-
-
Ryter, S.W.1
Choi, A.M.2
-
58
-
-
84880178772
-
Autophagy: A potential therapeutic target in lung diseases
-
Nakahira K, Choi AM. Autophagy: a potential therapeutic target in lung diseases. Am J Physiol Lung Cell Mol Physiol 2013;305:L93-L107.
-
(2013)
Am J Physiol Lung Cell Mol Physiol
, vol.305
, pp. L93-L107
-
-
Nakahira, K.1
Choi, A.M.2
-
59
-
-
57649198447
-
Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease
-
Ju JS, Miller SE, Hanson PI, Weihl CC. Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease. J Biol Chem 2008;283:30289-30299.
-
(2008)
J Biol Chem
, vol.283
, pp. 30289-30299
-
-
Ju, J.S.1
Miller, S.E.2
Hanson, P.I.3
Weihl, C.C.4
-
60
-
-
84892611793
-
Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration
-
Richter-Landsberg C, Leyk J. Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration. Acta Neuropathol 2013;126:793-807.
-
(2013)
Acta Neuropathol
, vol.126
, pp. 793-807
-
-
Richter-Landsberg, C.1
Leyk, J.2
-
61
-
-
79957916551
-
P62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
-
Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, et al. p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects. Autophagy 2011;7:572-583.
-
(2011)
Autophagy
, vol.7
, pp. 572-583
-
-
Bartlett, B.J.1
Isakson, P.2
Lewerenz, J.3
Sanchez, H.4
Kotzebue, R.W.5
Cumming, R.C.6
Harris, G.L.7
Nezis, I.P.8
Schubert, D.R.9
Simonsen, A.10
-
62
-
-
0035163063
-
Identification of components of the murine histone deacetylase 6 complex: Link between acetylation and ubiquitination signaling pathways
-
Seigneurin-Berny D, Verdel A, Curtet S, Lemercier C, Garin J, Rousseaux S, Khochbin S. Identification of components of the murine histone deacetylase 6 complex: link between acetylation and ubiquitination signaling pathways. Mol Cell Biol 2001;21:8035-8044.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8035-8044
-
-
Seigneurin-Berny, D.1
Verdel, A.2
Curtet, S.3
Lemercier, C.4
Garin, J.5
Rousseaux, S.6
Khochbin, S.7
-
63
-
-
33746541576
-
HDAC6-p97/VCP controlled polyubiquitin chain turnover
-
Boyault C, Gilquin B, Zhang Y, Rybin V, Garman E, Meyer-Klaucke W, Matthias P, Muller CW, Khochbin S. HDAC6-p97/VCP controlled polyubiquitin chain turnover. EMBO J 2006;25:3357-3366.
-
(2006)
EMBO J
, vol.25
, pp. 3357-3366
-
-
Boyault, C.1
Gilquin, B.2
Zhang, Y.3
Rybin, V.4
Garman, E.5
Meyer-Klaucke, W.6
Matthias, P.7
Muller, C.W.8
Khochbin, S.9
-
64
-
-
57149130824
-
AAA ATPase p97/VCP: Cellular functions, disease and therapeutic potential
-
Vij N. AAA ATPase p97/VCP: cellular functions, disease and therapeutic potential. J Cell Mol Med 2008;12:2511-2518.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 2511-2518
-
-
Vij, N.1
-
65
-
-
30644465041
-
Dominant-negative effect of mutant valosin-containing protein in aggresome formation
-
Kitami MI, Kitami T, Nagahama M, Tagaya M, Hori S, Kakizuka A, Mizuno Y, Hattori N. Dominant-negative effect of mutant valosin-containing protein in aggresome formation. FEBS Lett 2006;580: 474-478.
-
(2006)
FEBS Lett
, vol.580
, pp. 474-478
-
-
Kitami, M.I.1
Kitami, T.2
Nagahama, M.3
Tagaya, M.4
Hori, S.5
Kakizuka, A.6
Mizuno, Y.7
Hattori, N.8
-
66
-
-
33749236210
-
Diverse functions with a common regulator: Ubiquitin takes command of an AAA ATPase
-
Ye Y. Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase. J Struct Biol 2006;156:29-40.
-
(2006)
J Struct Biol
, vol.156
, pp. 29-40
-
-
Ye, Y.1
-
68
-
-
79952843826
-
The role of ubiquitin in autophagy-dependent protein aggregate processing
-
Yao TP. The role of ubiquitin in autophagy-dependent protein aggregate processing. Genes Cancer 2010;1:779-786.
-
(2010)
Genes Cancer
, vol.1
, pp. 779-786
-
-
Yao, T.P.1
-
69
-
-
27944504351
-
P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol 2005;171:603-614.
-
(2005)
J Cell Biol
, vol.171
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
70
-
-
84863609087
-
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome
-
Fusco C, Micale L, Egorov M, Monti M, D'Addetta EV, Augello B, Cozzolino F, Calcagni A, Fontana A, Polishchuk RS, et al. The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. PLoS One 2012;7:e40440.
-
(2012)
PLoS One
, vol.7
, pp. e40440
-
-
Fusco, C.1
Micale, L.2
Egorov, M.3
Monti, M.4
D'Addetta, E.V.5
Augello, B.6
Cozzolino, F.7
Calcagni, A.8
Fontana, A.9
Polishchuk, R.S.10
-
71
-
-
60849099049
-
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates
-
Kirkin V, Lamark T, Sou YS, Bjorkoy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, et al. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell 2009;33:505-516.
-
(2009)
Mol Cell
, vol.33
, pp. 505-516
-
-
Kirkin, V.1
Lamark, T.2
Sou, Y.S.3
Bjorkoy, G.4
Nunn, J.L.5
Bruun, J.A.6
Shvets, E.7
McEwan, D.G.8
Clausen, T.H.9
Wild, P.10
-
72
-
-
84859736977
-
Aggrephagy: Selective disposal of protein aggregates by macroautophagy
-
Lamark T, Johansen T. Aggrephagy: selective disposal of protein aggregates by macroautophagy. Int J Cell Biol 2012; 736905.
-
(2012)
Int J Cell Biol
, pp. 736905
-
-
Lamark, T.1
Johansen, T.2
-
73
-
-
13644256191
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
-
Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, Kaufman RJ, Ma D, Coen DM, Ron D, et al. A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 2005;307:935-939.
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
Kaufman, R.J.7
Ma, D.8
Coen, D.M.9
Ron, D.10
-
74
-
-
84869798280
-
Salubrinal protects against cigarette smoke extract-induced HBEpC apoptosis likely via regulating the activity of PERK-eIF2alpha signaling pathway
-
Yuan T, Luo BL, Wei TH, Zhang L, He BM, Niu RC. Salubrinal protects against cigarette smoke extract-induced HBEpC apoptosis likely via regulating the activity of PERK-eIF2alpha signaling pathway. Arch Med Res 2012;43:522-529.
-
(2012)
Arch Med Res
, vol.43
, pp. 522-529
-
-
Yuan, T.1
Luo, B.L.2
Wei, T.H.3
Zhang, L.4
He, B.M.5
Niu, R.C.6
-
75
-
-
79953171555
-
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
-
Chou TF, Brown SJ, Minond D, Nordin BE, Li K, Jones AC, Chase P, Porubsky PR, Stoltz BM, Schoenen FJ, et al. Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways. Proc Natl Acad Sci USA 2011;108:4834-4839.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4834-4839
-
-
Chou, T.F.1
Brown, S.J.2
Minond, D.3
Nordin, B.E.4
Li, K.5
Jones, A.C.6
Chase, P.7
Porubsky, P.R.8
Stoltz, B.M.9
Schoenen, F.J.10
-
76
-
-
78650434097
-
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
-
Chen ZH, Lam HC, Jin Y, Kim HP, Cao J, Lee SJ, Ifedigbo E, Parameswaran H, Ryter SW, Choi AM. Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proc Natl Acad Sci USA 2010;107:18880-18885.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18880-18885
-
-
Zh, C.1
Lam, H.C.2
Jin, Y.3
Kim, H.P.4
Cao, J.5
Lee, S.J.6
Ifedigbo, E.7
Parameswaran, H.8
Ryter, S.W.9
Choi, A.M.10
|