Atg7 enhances host defense against infection via downregulation of superoxide but upregulation of nitric oxide

Journal of Immunology

Volumn 194, Issue 3, 2015, Pages 1112-1121

  Li, Xuefeng ^a,b   Ye, Yan ^a   Zhou, Xikun ^a,b   Huang, Canhua ^b   Wu, Min ^a  

^a UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HYDROGEN PEROXIDE; JANUS KINASE 2; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN ATG7; PROTEIN TYROSINE PHOSPHATASE SHP 2; REACTIVE OXYGEN METABOLITE; STAT1 PROTEIN; STAT1ALPHA PROTEIN; SUPEROXIDE; UBIQUITIN; UNCLASSIFIED DRUG; ATG7 PROTEIN, MOUSE; INDUCIBLE NITRIC OXIDE SYNTHASE; MICROTUBULE ASSOCIATED PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BACTERIAL CLEARANCE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HOST RESISTANCE; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS CELL; LUNG INJURY; MORTALITY; MOUSE; NONHUMAN; OXIDATION KINETICS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PSEUDOMONAS INFECTION; UPREGULATION; ANIMAL; DEFICIENCY; DISEASE MODEL; GENE SILENCING; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INFECTION; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MICROBIOLOGY; PSEUDOMONAS AERUGINOSA; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; AUTOPHAGY; DISEASE MODELS, ANIMAL; GENE KNOCKDOWN TECHNIQUES; HOST-PATHOGEN INTERACTIONS; INFECTION; INTERFERON-GAMMA; JANUS KINASE 2; MACROPHAGES; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PNEUMOCYTES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; SUPEROXIDES;

EID: 84921529601     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401958     Document Type: Article

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