Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice

Annals of Surgery

Volumn 257, Issue 2, 2013, Pages 352-363

  Lo, Steven ^a,c   Yuan, Shyng Shiou F ^a   Hsu, Chin ^b   Cheng, Yu Jen ^a   Chang, Ya Fang ^a   Hsueh, Hsiang Wei ^a   Lee, Po Huang ^a   Hsieh, Ya Ching ^a  

^a I SHOU UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

autophagy; cell death; inflammation; septic shock

Indexed keywords

ACID PHOSPHATASE; ALBUMIN; ANTIINFLAMMATORY AGENT; BAFILOMYCIN A1; BECLIN 1; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 6; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2A; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; RAB7 PROTEIN; RESPIRATORY TRACT AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL FUSION; CELL VACUOLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; LIGATION; LUNG EDEMA; LYSOSOME; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PUNCTURE; SEPSIS; SURVIVAL RATE;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELL DEATH; ENZYME INHIBITORS; LUNG INJURY; LYSOSOMES; MACROLIDES; MALE; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; VACUOLES;

EID: 84872298070     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e318269d0e2     Document Type: Article

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