Vam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function

Acta Pharmacologica Sinica

Volumn 35, Issue 6, 2014, Pages 779-791

  Xuan, Ling Ling ^a   Shi, Ji ^a,b   Yao, Chun Suo ^a   Bai, Jin Ye ^a   Qu, Feng ^a   Zhang, Jin Lan ^a   Hou, Qi ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

apoptosis; Bax; bronchial epithelial cell; ceramide; cigarette smoking; lung; mitochondria; resveratrol; sphingomyelinase; Vam3

Indexed keywords

CASPASE 9; CERAMIDE; CIGARETTE SMOKE; CIGARETTE SMOKE CONDENSATE; CYTOCHROME C; DIMER; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; RESVERATROL; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; VAM3; ANTIASTHMATIC AGENT; SMOKE; STILBENE DERIVATIVE;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; FLUORESCENCE SPECTROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MALE; MCF 7 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; CYTOLOGY; DIMERIZATION; DRUG EFFECTS; LUNG; METABOLISM; MITOCHONDRION; RESPIRATORY TRACT MUCOSA; SMOKE; SMOKING; TOBACCO; VITIS;

ANIMALS; ANTI-ASTHMATIC AGENTS; APOPTOSIS; CASPASE 9; CELL LINE; CYTOCHROMES C; DIMERIZATION; HUMANS; LUNG; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED BALB C; MITOCHONDRIA; RESPIRATORY MUCOSA; SMOKE; SMOKING; STILBENES; TOBACCO; VITIS;

EID: 84902285069     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2014.17     Document Type: Article

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