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Volumn 309, Issue 6, 2015, Pages L552-L561

Reduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices

Author keywords

Autophagy; Cell viability; Collagen matrix; Forkhead box O3a; Idiopathic pulmonary fibrosis fibroblasts; Light chain 3B

Indexed keywords

COLLAGEN; MESSENGER RNA; PROTEIN KINASE B; TRANSCRIPTION FACTOR FOXO; CULTURE MEDIUM; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; MAP1LC3B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN;

EID: 84941766194     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00079.2015     Document Type: Article
Times cited : (76)

References (33)
  • 1
    • 50349098499 scopus 로고    scopus 로고
    • Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3
    • Allard D, Figg N, Bennett MR, Littlewood TD. Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3. J Biol Chem 283: 19739–19747, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 19739-19747
    • Allard, D.1    Figg, N.2    Bennett, M.R.3    Littlewood, T.D.4
  • 2
    • 25444467151 scopus 로고    scopus 로고
    • Growth factors in idiopathic pulmonary fibrosis: Relative roles
    • Allen JT, Spiteri MA. Growth factors in idiopathic pulmonary fibrosis: relative roles. Respir Res 3: 13, 2002.
    • (2002) Respir Res , vol.3 , pp. 13
    • Allen, J.T.1    Spiteri, M.A.2
  • 4
    • 84883655855 scopus 로고    scopus 로고
    • Hidden behind autophagy: The unconventional roles of ATG proteins
    • Bestebroer J, V’Kovski P, Mauthe M, Reggiori F. Hidden behind autophagy: the unconventional roles of ATG proteins. Traffic 14: 1029-1041, 2013.
    • (2013) Traffic , vol.14 , pp. 1029-1041
    • Bestebroer, J.1    V’Kovski, P.2    Mauthe, M.3    Reggiori, F.4
  • 5
    • 0037323903 scopus 로고    scopus 로고
    • Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors
    • Birkenkamp KU, Coffer PJ. Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors. Biochem Soc Trans 31: 292–297, 2003.
    • (2003) Biochem Soc Trans , vol.31 , pp. 292-297
    • Birkenkamp, K.U.1    Coffer, P.J.2
  • 6
  • 7
    • 84893681263 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: From epithelial injury to biomarkers—insights from the bench side
    • Borensztajn K, Crestani B, Kolb M. Idiopathic pulmonary fibrosis: from epithelial injury to biomarkers—insights from the bench side. Respiration 86: 441–452, 2013.
    • (2013) Respiration , vol.86 , pp. 441-452
    • Borensztajn, K.1    Crestani, B.2    Kolb, M.3
  • 8
    • 84880376355 scopus 로고    scopus 로고
    • Emerging regulation and functions of autophagy
    • Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nat Cell Biol 15: 713–720, 2013.
    • (2013) Nat Cell Biol , vol.15 , pp. 713-720
    • Boya, P.1    Reggiori, F.2    Codogno, P.3
  • 10
    • 34247612439 scopus 로고    scopus 로고
    • New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis: A potential role for stem cells in the lung parenchyma and implications for therapy
    • Gharaee-Kermani M, Gyetko MR, Hu B, Phan SH. New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis: a potential role for stem cells in the lung parenchyma and implications for therapy. Pharm Res 24: 819–841, 2007.
    • (2007) Pharm Res , vol.24 , pp. 819-841
    • Gharaee-Kermani, M.1    Gyetko, M.R.2    Hu, B.3    Phan, S.H.4
  • 11
    • 84855196235 scopus 로고    scopus 로고
    • Decreased expression of Beclin-1 and LC3 in human lung cancer
    • Jiang ZF, Shao LJ, Wang WM, Yan XB, Liu RY. Decreased expression of Beclin-1 and LC3 in human lung cancer. Mol Biol Rep 39: 259–267, 2012.
    • (2012) Mol Biol Rep , vol.39 , pp. 259-267
    • Jiang, Z.F.1    Shao, L.J.2    Wang, W.M.3    Yan, X.B.4    Liu, R.Y.5
  • 13
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 40: 280–293, 2010.
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 14
    • 0024822235 scopus 로고
    • An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis
    • Kuhn C III, Boldt J, King TE Jr, Crouch E, Vartio T, McDonald JA. An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis. Am Rev Respir Dis 140: 1693–1703, 1989.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1693-1703
    • Kuhn, C.1    Boldt, J.2    King, T.E.3    Crouch, E.4    Vartio, T.5    McDonald, J.A.6
  • 15
    • 0025729855 scopus 로고
    • The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis
    • Kuhn C, McDonald JA. The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis. Am J Pathol 138: 1257–1265, 1991.
    • (1991) Am J Pathol , vol.138 , pp. 1257-1265
    • Kuhn, C.1    McDonald, J.A.2
  • 16
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 132: 27–42, 2008.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 17
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 469: 323–335, 2011.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 18
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • Levine B, Yuan J. Autophagy in cell death: an innocent convict? J Clin Invest 115: 2679–2688, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 20
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 140: 313–326, 2010.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 21
    • 84899639570 scopus 로고    scopus 로고
    • IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases
    • Nho RS, Hergert P. IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases. PLoS One 9: e94616, 2014.
    • (2014) Plos One , vol.9
    • Nho, R.S.1    Hergert, P.2
  • 22
    • 80055025175 scopus 로고    scopus 로고
    • Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrix
    • Nho RS, Hergert P, Kahm J, Jessurun J, Henke C. Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrix. Am J Pathol 179: 2420–2430, 2011.
    • (2011) Am J Pathol , vol.179 , pp. 2420-2430
    • Nho, R.S.1    Hergert, P.2    Kahm, J.3    Jessurun, J.4    Henke, C.5
  • 23
    • 84908078242 scopus 로고    scopus 로고
    • MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix
    • Nho RS, Im J, Ho YY, Hergert P. MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix. Am J Physiol Lung Cell Mol Physiol 307: L632–L642, 2014.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.307 , pp. L632-L642
    • Nho, R.S.1    Im, J.2    Ho, Y.Y.3    Hergert, P.4
  • 24
    • 84875985279 scopus 로고    scopus 로고
    • FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas
    • Nho RS, Peterson M, Hergert P, Henke CA. FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas. PLoS One 8: e61017, 2013.
    • (2013) Plos One , vol.8
    • Nho, R.S.1    Peterson, M.2    Hergert, P.3    Henke, C.A.4
  • 25
    • 22544463394 scopus 로고    scopus 로고
    • Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway
    • Nho RS, Xia H, Kahm J, Kleidon J, Diebold D, Henke CA. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. J Biol Chem 280: 26630–26639, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 26630-26639
    • Nho, R.S.1    Xia, H.2    Kahm, J.3    Kleidon, J.4    Diebold, D.5    Henke, C.A.6
  • 28
    • 70350500068 scopus 로고    scopus 로고
    • FoxO transcription factors promote autophagy in cardiomyocytes
    • Sengupta A, Molkentin JD, Yutzey KE. FoxO transcription factors promote autophagy in cardiomyocytes. J Biol Chem 284: 28319–28331, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 28319-28331
    • Sengupta, A.1    Molkentin, J.D.2    Yutzey, K.E.3
  • 29
    • 0030800795 scopus 로고    scopus 로고
    • Adenovectormediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung
    • Sime PJ, Xing Z, Graham FL, Csaky KG, Gauldie J. Adenovectormediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J Clin Invest 100: 768–776, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 768-776
    • Sime, P.J.1    Xing, Z.2    Graham, F.L.3    Csaky, K.G.4    Gauldie, J.5
  • 30
    • 84865820041 scopus 로고    scopus 로고
    • TGF- activation and lung fibrosis
    • Tatler AL, Jenkins G. TGF- activation and lung fibrosis. Proc Am Thorac Soc 9: 130–136, 2012.
    • (2012) Proc am Thorac Soc , vol.9 , pp. 130-136
    • Tatler, A.L.1    Jenkins, G.2
  • 33
    • 36448968532 scopus 로고    scopus 로고
    • FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
    • Zhao J, Brault JJ, Schild A, Cao P, Sandri M, Schiaffino S, Lecker SH, Goldberg AL. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 6: 472–483, 2007.
    • (2007) Cell Metab , vol.6 , pp. 472-483
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Cao, P.4    Sandri, M.5    Schiaffino, S.6    Lecker, S.H.7    Goldberg, A.L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.