Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation

Free Radical Biology and Medicine

Volumn 85, Issue , 2015, Pages 83-94

  Jurkuvenaite, Asta ^a,b   Benavides, Gloria A ^c,d   Komarova, Svetlana ^a   Doran, Stephen F ^a   Johnson, Michelle ^c,d   Aggarwal, Saurabh ^a,b,d   Zhang, Jianhua ^c,d,e   Darley Usmar, Victor M ^c,d   Matalon, Sadis ^a,b,d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^e BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

3 Methyladenine; Autophagy; Bioenergetics; Chlorine; Free radicals; Lung injury; Mitochondrial dysfunction; MitoQ; Trehalose

Indexed keywords

3 METHYLADENINE; CHLORINE; DRINKING WATER; TREHALOSE;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; AUTOPHAGY; BIOENERGY; CELL DAMAGE; CELL DEATH; CELL MEMBRANE PERMEABILITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; INHALATION; LEUKOCYTE; LUNG ALVEOLUS CELL; LUNG LAVAGE; MITOCHONDRIAL INJURY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; UPREGULATION; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; ENERGY METABOLISM; INFLAMMATION; LUNG; METABOLISM; MITOCHONDRION;

MUS;

ANIMALS; AUTOPHAGY; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CHLORINE; ENERGY METABOLISM; HUMANS; INFLAMMATION; LUNG; MICE; MITOCHONDRIA; UP-REGULATION;

EID: 84930965674     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.03.039     Document Type: Article

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