MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 306, Issue 7, 2014, Pages

  Mannam, Praveen ^a   Shinn, Amanda S ^a   Srivastava, Anup ^a   Neamu, Radu F ^c   Walker, Wendy E ^a   Bohanon, Michael ^b   Merkel, Jane ^b   Kang, Min Jong ^a   Dela Cruz, Charles S ^a   Ahasic, Amy M ^a   Pisani, Margaret A ^a   Trentalange, Mark ^a   Phillip West, A ^a   Shadel, Gerald S ^a   Elias, Jack A ^a   Lee, Patty J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Biogenesis; Lung injury; Mitochondria; Mitogen activated protein kinases; Mitophagy; Sepsis

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; PARKIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN; PROTEIN PINK1; REACTIVE OXYGEN METABOLITE; SIRTUIN 1; TRANSCRIPTION FACTOR NRF1; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CELL STRESS; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; INFECTION RESISTANCE; LUNG ENDOTHELIUM; LUNG INJURY; MACROPHAGE; MALE; MITOCHONDRION; MITOPHAGY; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SEPSIS; VERY ELDERLY;

BIOGENESIS; LUNG INJURY; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; MITOPHAGY; SEPSIS;

AGED; AGED, 80 AND OVER; ANIMALS; ENDOTHELIAL CELLS; FEMALE; HUMANS; LIPOPOLYSACCHARIDES; LUNG; LUNG INJURY; MALE; MAP KINASE KINASE 3; MICE; MIDDLE AGED; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; PROTEIN KINASES; SEPSIS; SIRTUIN 1; UBIQUITIN-PROTEIN LIGASES;

EID: 84900523766     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00272.2013     Document Type: Article

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