Mitochondrial-targeted DNA repair enzyme 8-oxoguanine DNA glycosylase 1 protects against ventilator-induced lung injury in intact mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 4, 2013, Pages

  Hashizume, Masahiro ^a,b   Mouner, Marc ^a   Chouteau, Joshua M ^b   Gorodnya, Olena M ^b   Ruchko, Mykhaylo V ^b   Potter, Barry J ^c   Wilson, Glenn L ^a   Gillespie, Mark N ^b   Parker, James C ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Albumin spaces; Glutathione; IL 6; Macrophage inflammatory protein 2; Pulmonary edema; Vascular permeability

Indexed keywords

8 OXOGUANINE DNA GLYCOSYLASE 1; ALBUMIN; DNA GLYCOSYLTRANSFERASE; HYBRID PROTEIN; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOCHONDRIAL DNA; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ALBUMIN BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE SEVERITY; DNA DAMAGE; DNA REPAIR; DRY WEIGHT; INJURY SEVERITY; LUNG BLOOD VESSEL; LUNG EDEMA; LUNG LAVAGE; LUNG PRESSURE; LUNG VENTILATION; LUNG WEIGHT; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN TARGETING; TIDAL VOLUME; VENTILATOR INDUCED LUNG INJURY; WET WEIGHT;

ANIMALS; CHEMOKINE CXCL2; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; DNA, MITOCHONDRIAL; GLUTATHIONE; INTERLEUKIN-6; KAPLAN-MEIER ESTIMATE; MICE; MITOCHONDRIA; PULMONARY EDEMA; VENTILATOR-INDUCED LUNG INJURY;

EID: 84874023358     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00071.2012     Document Type: Article

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