-
1
-
-
65249188790
-
Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI
-
COI: 1:CAS:528:DC%2BD1MXotVyqsLg%3D, PID: 19211846
-
Abramovici H, Mojtabaie P, Parks RJ, Zhong XP, Koretzky GA, Topham MK, Gee SH (2009) Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI. Mol Biol Cell 20:2049–2059
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2049-2059
-
-
Abramovici, H.1
Mojtabaie, P.2
Parks, R.J.3
Zhong, X.P.4
Koretzky, G.A.5
Topham, M.K.6
Gee, S.H.7
-
2
-
-
84938271321
-
Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder
-
COI: 1:CAS:528:DC%2BC2MXht1WltLjP, PID: 26168012
-
Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez MA, Campeanu IJ, Griffin LB, Groenewald S, Strickland AV (2015) Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder. Nat Genet 47:926–932
-
(2015)
Nat Genet
, vol.47
, pp. 926-932
-
-
Abrams, A.J.1
Hufnagel, R.B.2
Rebelo, A.3
Zanna, C.4
Patel, N.5
Gonzalez, M.A.6
Campeanu, I.J.7
Griffin, L.B.8
Groenewald, S.9
Strickland, A.V.10
-
3
-
-
84935013862
-
Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly
-
COI: 1:CAS:528:DC%2BC2MXps1CltL4%3D, PID: 26056272
-
AhYoung AP, Jiang J, Zhang J, Khoi Dang X, Loo JA, Zhou ZH, Egea PF (2015) Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly. Proc Natl Acad Sci U S A 112:E3179–E3188
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. E3179-E3188
-
-
AhYoung, A.P.1
Jiang, J.2
Zhang, J.3
Khoi Dang, X.4
Loo, J.A.5
Zhou, Z.H.6
Egea, P.F.7
-
4
-
-
34249693479
-
A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy
-
PID: 17314202
-
Alavi MV, Bette S, Schimpf S, Schuettauf F, Schraermeyer U, Wehrl HF, Ruttiger L, Beck SC, Tonagel F, Pichler BJ, Knipper M, Peters T, Laufs J, Wissinger B (2007) A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy. Brain 130:1029–1042
-
(2007)
Brain
, vol.130
, pp. 1029-1042
-
-
Alavi, M.V.1
Bette, S.2
Schimpf, S.3
Schuettauf, F.4
Schraermeyer, U.5
Wehrl, H.F.6
Ruttiger, L.7
Beck, S.C.8
Tonagel, F.9
Pichler, B.J.10
Knipper, M.11
Peters, T.12
Laufs, J.13
Wissinger, B.14
-
5
-
-
0025013378
-
Mitochondrial contact sites. Lipid composition and dynamics
-
COI: 1:CAS:528:DyaK3cXmtVOjtbs%3D, PID: 2172233
-
Ardail D, Privat JP, Egret-Charlier M, Levrat C, Lerme F, Louisot P (1990) Mitochondrial contact sites. Lipid composition and dynamics. J Biol Chem 265:18797–18802
-
(1990)
J Biol Chem
, vol.265
, pp. 18797-18802
-
-
Ardail, D.1
Privat, J.P.2
Egret-Charlier, M.3
Levrat, C.4
Lerme, F.5
Louisot, P.6
-
6
-
-
73649098791
-
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria
-
COI: 1:CAS:528:DC%2BC3cXhslSjt78%3D, PID: 19834068
-
Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM, Yu WH, Duff KE, Yaffe MP, Pon LA (2009) Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol 175:1810–1816
-
(2009)
Am J Pathol
, vol.175
, pp. 1810-1816
-
-
Area-Gomez, E.1
de Groof, A.J.2
Boldogh, I.3
Bird, T.D.4
Gibson, G.E.5
Koehler, C.M.6
Yu, W.H.7
Duff, K.E.8
Yaffe, M.P.9
Pon, L.A.10
-
7
-
-
84868524156
-
Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
-
COI: 1:CAS:528:DC%2BC38XhtF2ru7jL, PID: 22892566
-
Area-Gomez E, Del Carmen Lara Castillo M, Tambini MD, Guardia-Laguarta C, de Groof AJ, Madra M, Ikenouchi J, Umeda M, Bird TD, Sturley SL, Schon EA (2012) Upregulated function of mitochondria-associated ER membranes in Alzheimer disease. EMBO J 31:4106–4123
-
(2012)
EMBO J
, vol.31
, pp. 4106-4123
-
-
Area-Gomez, E.1
Del Carmen Lara Castillo, M.2
Tambini, M.D.3
Guardia-Laguarta, C.4
de Groof, A.J.5
Madra, M.6
Ikenouchi, J.7
Umeda, M.8
Bird, T.D.9
Sturley, S.L.10
Schon, E.A.11
-
8
-
-
84903197320
-
Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking
-
COI: 1:CAS:528:DC%2BC2cXhtVarsrrN, PID: 24815354
-
Barbero-Camps E, Fernández A, Baulies A, Martinez L, Fernández-Checa JC, Colell A (2014) Endoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol trafficking. Am J Pathol 184:2066–2081
-
(2014)
Am J Pathol
, vol.184
, pp. 2066-2081
-
-
Barbero-Camps, E.1
Fernández, A.2
Baulies, A.3
Martinez, L.4
Fernández-Checa, J.C.5
Colell, A.6
-
9
-
-
33947224038
-
Brain neutral lipids mass is increased in α-synuclein gene-ablated mice
-
PID: 17250686
-
Barceló-Coblijn G, Golovko MY, Weinhofer I, Berger J, Murphy EJ (2007) Brain neutral lipids mass is increased in α-synuclein gene-ablated mice. J Neurochem 101:132–141
-
(2007)
J Neurochem
, vol.101
, pp. 132-141
-
-
Barceló-Coblijn, G.1
Golovko, M.Y.2
Weinhofer, I.3
Berger, J.4
Murphy, E.J.5
-
10
-
-
0344392841
-
A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery
-
COI: 1:CAS:528:DC%2BD3sXpt1ymtL0%3D, PID: 13679517
-
Boldogh IR, Nowakowski DW, Yang HC, Chung H, Karmon S, Royes P, Pon LA (2003) A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery. Mol Biol Cell 14:4618–4627
-
(2003)
Mol Biol Cell
, vol.14
, pp. 4618-4627
-
-
Boldogh, I.R.1
Nowakowski, D.W.2
Yang, H.C.3
Chung, H.4
Karmon, S.5
Royes, P.6
Pon, L.A.7
-
11
-
-
0030919567
-
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia
-
COI: 1:CAS:528:DyaK2sXjsF2qtLs%3D, PID: 9153527
-
Browne SE, Bowling AC, Macgarvey U, Baik MJ, Berger SC, Muquit MM, Bird ED, Beal MF (1997) Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia. Ann Neurol 41:646–653
-
(1997)
Ann Neurol
, vol.41
, pp. 646-653
-
-
Browne, S.E.1
Bowling, A.C.2
Macgarvey, U.3
Baik, M.J.4
Berger, S.C.5
Muquit, M.M.6
Bird, E.D.7
Beal, M.F.8
-
12
-
-
77649259094
-
ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD
-
COI: 1:CAS:528:DC%2BC3cXis1Clurg%3D, PID: 20133765
-
Bryleva EY, Rogers MA, Chang CC, Buen F, Harris BT, Rousselet E, Seidah NG, Oddo S, LaFerla FM, Spencer TA, Hickey WF, Chang TY (2010) ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. Proc Natl Acad Sci U S A 107:3081–3086
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3081-3086
-
-
Bryleva, E.Y.1
Rogers, M.A.2
Chang, C.C.3
Buen, F.4
Harris, B.T.5
Rousselet, E.6
Seidah, N.G.7
Oddo, S.8
LaFerla, F.M.9
Spencer, T.A.10
Hickey, W.F.11
Chang, T.Y.12
-
13
-
-
84926258887
-
Disturbed mitochondrial dynamics and neurodegenerative disorders
-
PID: 25486875
-
Burté F, Carelli V, Chinnery PF, Yu-Wai-Man P (2015) Disturbed mitochondrial dynamics and neurodegenerative disorders. Nat Rev Neurol 11:11–24
-
(2015)
Nat Rev Neurol
, vol.11
, pp. 11-24
-
-
Burté, F.1
Carelli, V.2
Chinnery, P.F.3
Yu-Wai-Man, P.4
-
14
-
-
33644987632
-
Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment
-
COI: 1:CAS:528:DC%2BD28XisFOqsrk%3D, PID: 16413966
-
Butterfield DA, Reed T, Perluigi M, De Marco C, Coccia R, Cini C, Sultana R (2006) Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment. Neurosci Lett 397:170–173
-
(2006)
Neurosci Lett
, vol.397
, pp. 170-173
-
-
Butterfield, D.A.1
Reed, T.2
Perluigi, M.3
De Marco, C.4
Coccia, R.5
Cini, C.6
Sultana, R.7
-
15
-
-
43149107699
-
Functional mitochondria are required for alpha-synuclein toxicity in aging yeast
-
PID: 18192273
-
Büttner S, Bitto A, Ring J, Augsten M, Zabrocki P, Eisenberg T, Jungwirth H, Hutter S, Carmona-Gutierrez D, Kroemer G, Winderickx J, Madeo F (2008) Functional mitochondria are required for alpha-synuclein toxicity in aging yeast. J Biol Chem 283:7554–7560
-
(2008)
J Biol Chem
, vol.283
, pp. 7554-7560
-
-
Büttner, S.1
Bitto, A.2
Ring, J.3
Augsten, M.4
Zabrocki, P.5
Eisenberg, T.6
Jungwirth, H.7
Hutter, S.8
Carmona-Gutierrez, D.9
Kroemer, G.10
Winderickx, J.11
Madeo, F.12
-
16
-
-
84888880539
-
Endonuclease G mediates alpha-synuclein cytotoxicity during Parkinson's disease
-
PID: 24129513
-
Büttner S, Habernig L, Broeskamp F, Ruli D, Vogtle FN, Vlachos M, Macchi F, Kuttner V, Carmona-Gutierrez D, Eisenberg T, Ring J, Markaki M, Taskin AA, Benke S, Ruckenstuhl C, Braun R, Van den Haute C, Bammens T, van der Perren A, Frohlich KU, Winderickx J, Kroemer G, Baekelandt V, Tavernarakis N, Kovacs GG, Dengjel J, Meisinger C, Sigrist SJ, Madeo F (2013) Endonuclease G mediates alpha-synuclein cytotoxicity during Parkinson's disease. EMBO J 32:3041–3054
-
(2013)
EMBO J
, vol.32
, pp. 3041-3054
-
-
Büttner, S.1
Habernig, L.2
Broeskamp, F.3
Ruli, D.4
Vogtle, F.N.5
Vlachos, M.6
Macchi, F.7
Kuttner, V.8
Carmona-Gutierrez, D.9
Eisenberg, T.10
Ring, J.11
Markaki, M.12
Taskin, A.A.13
Benke, S.14
Ruckenstuhl, C.15
Braun, R.16
Van den Haute, C.17
Bammens, T.18
van der Perren, A.19
Frohlich, K.U.20
Winderickx, J.21
Kroemer, G.22
Baekelandt, V.23
Tavernarakis, N.24
Kovacs, G.G.25
Dengjel, J.26
Meisinger, C.27
Sigrist, S.J.28
Madeo, F.29
more..
-
17
-
-
84861554724
-
alpha-Synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions
-
COI: 1:CAS:528:DC%2BC38XnsF2nsb0%3D, PID: 22453917
-
Cali T, Ottolini D, Negro A, Brini M (2012) alpha-Synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions. J Biol Chem 287:17914–17929
-
(2012)
J Biol Chem
, vol.287
, pp. 17914-17929
-
-
Cali, T.1
Ottolini, D.2
Negro, A.3
Brini, M.4
-
18
-
-
81255190781
-
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
-
COI: 1:CAS:528:DC%2BC3MXhsVGrsbnI, PID: 21873260
-
Calkins MJ, Manczak M, Mao P, Shirendeb U, Reddy PH (2011) Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease. Hum Mol Genet 20:4515–4529
-
(2011)
Hum Mol Genet
, vol.20
, pp. 4515-4529
-
-
Calkins, M.J.1
Manczak, M.2
Mao, P.3
Shirendeb, U.4
Reddy, P.H.5
-
19
-
-
79251535590
-
Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease
-
PID: 21151659
-
Chadwick W, Brenneman R, Martin B, Maudsley S (2010) Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease. Int J Alzheimers Dis 2010:604792
-
(2010)
Int J Alzheimers Dis
, vol.2010
, pp. 604792
-
-
Chadwick, W.1
Brenneman, R.2
Martin, B.3
Maudsley, S.4
-
20
-
-
33750445482
-
Mitochondrial fusion and fission in mammals
-
COI: 1:CAS:528:DC%2BD28Xht1yjs7vN, PID: 16704336
-
Chan DC (2006) Mitochondrial fusion and fission in mammals. Annu Rev Cell Dev Biol 22:79–99
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 79-99
-
-
Chan, D.C.1
-
21
-
-
84870018735
-
Phosphatidylserine decarboxylase 1 (Psd1) promotes mitochondrial fusion by regulating the biophysical properties of the mitochondrial membrane and alternative topogenesis of mitochondrial genome maintenance protein 1 (Mgm1)
-
COI: 1:CAS:528:DC%2BC38XhslansbvO, PID: 23045528
-
Chan EY, McQuibban GA (2012) Phosphatidylserine decarboxylase 1 (Psd1) promotes mitochondrial fusion by regulating the biophysical properties of the mitochondrial membrane and alternative topogenesis of mitochondrial genome maintenance protein 1 (Mgm1). J Biol Chem 287:40131–40139
-
(2012)
J Biol Chem
, vol.287
, pp. 40131-40139
-
-
Chan, E.Y.1
McQuibban, G.A.2
-
22
-
-
22544451586
-
Disruption of fusion results in mitochondrial heterogeneity and dysfunction
-
COI: 1:CAS:528:DC%2BD2MXlvFymt7s%3D, PID: 15899901
-
Chen H, Chomyn A, Chan DC (2005) Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J Biol Chem 280:26185–26192
-
(2005)
J Biol Chem
, vol.280
, pp. 26185-26192
-
-
Chen, H.1
Chomyn, A.2
Chan, D.C.3
-
23
-
-
3543141113
-
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
-
COI: 1:CAS:528:DC%2BD2cXlt1WlsL4%3D, PID: 15163634
-
Choo YS, Johnson GV, MacDonald M, Detloff PJ, Lesort M (2004) Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release. Hum Mol Genet 13:1407–1420
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1407-1420
-
-
Choo, Y.S.1
Johnson, G.V.2
MacDonald, M.3
Detloff, P.J.4
Lesort, M.5
-
24
-
-
84885176082
-
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
-
COI: 1:CAS:528:DC%2BC3sXhsVeqsbvE, PID: 24036476
-
Chu CT, Ji J, Dagda RK, Jiang JF, Tyurina YY, Kapralov AA, Tyurin VA, Yanamala N, Shrivastava IH, Mohammadyani D (2013) Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. Nat Cell Biol 15:1197–1205
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1197-1205
-
-
Chu, C.T.1
Ji, J.2
Dagda, R.K.3
Jiang, J.F.4
Tyurina, Y.Y.5
Kapralov, A.A.6
Tyurin, V.A.7
Yanamala, N.8
Shrivastava, I.H.9
Mohammadyani, D.10
-
25
-
-
84866173763
-
Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease
-
COI: 1:CAS:528:DC%2BC38XhtlOmtLnN, PID: 22773688
-
Ciarlo L, Manganelli V, Matarrese P, Garofalo T, Tinari A, Gambardella L, Marconi M, Grasso M, Misasi R, Sorice M, Malorni W (2012) Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease. J Lipid Res 53:2057–2068
-
(2012)
J Lipid Res
, vol.53
, pp. 2057-2068
-
-
Ciarlo, L.1
Manganelli, V.2
Matarrese, P.3
Garofalo, T.4
Tinari, A.5
Gambardella, L.6
Marconi, M.7
Grasso, M.8
Misasi, R.9
Sorice, M.10
Malorni, W.11
-
26
-
-
78650284389
-
Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli
-
COI: 1:CAS:528:DC%2BC3MXosFeiug%3D%3D, PID: 21069748
-
Costa V, Giacomello M, Hudec R, Lopreiato R, Ermak G, Lim D, Malorni W, Davies KJ, Carafoli E, Scorrano L (2010) Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli. EMBO Mol Med 2:490–503
-
(2010)
EMBO Mol Med
, vol.2
, pp. 490-503
-
-
Costa, V.1
Giacomello, M.2
Hudec, R.3
Lopreiato, R.4
Ermak, G.5
Lim, D.6
Malorni, W.7
Davies, K.J.8
Carafoli, E.9
Scorrano, L.10
-
27
-
-
0036789845
-
Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress–induced death of motor neurons in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD38XotlOjtr4%3D, PID: 12325074
-
Cutler RG, Pedersen WA, Camandola S, Rothstein JD, Mattson MP (2002) Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress–induced death of motor neurons in amyotrophic lateral sclerosis. Ann Neurol 52:448–457
-
(2002)
Ann Neurol
, vol.52
, pp. 448-457
-
-
Cutler, R.G.1
Pedersen, W.A.2
Camandola, S.3
Rothstein, J.D.4
Mattson, M.P.5
-
28
-
-
1242338183
-
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
-
COI: 1:CAS:528:DC%2BD2cXhs1Srsrw%3D, PID: 14970312
-
Cutler RG, Kelly J, Storie K, Pedersen WA, Tammara A, Hatanpaa K, Troncoso JC, Mattson MP (2004) Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proc Natl Acad Sci U S A 101:2070–2075
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2070-2075
-
-
Cutler, R.G.1
Kelly, J.2
Storie, K.3
Pedersen, W.A.4
Tammara, A.5
Hatanpaa, K.6
Troncoso, J.C.7
Mattson, M.P.8
-
29
-
-
0032540327
-
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
-
COI: 1:CAS:528:DyaK1cXivVOrs7s%3D, PID: 9545270
-
Davidson WS, Jonas A, Clayton DF, George JM (1998) Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes. J Biol Chem 273:9443–9449
-
(1998)
J Biol Chem
, vol.273
, pp. 9443-9449
-
-
Davidson, W.S.1
Jonas, A.2
Clayton, D.F.3
George, J.M.4
-
30
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
PID: 19052620
-
de Brito OM, Scorrano L (2008) Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456:605–610
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
de Brito, O.M.1
Scorrano, L.2
-
31
-
-
84863393591
-
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
-
PID: 22131369
-
De Vos KJ, Morotz GM, Stoica R, Tudor EL, Lau KF, Ackerley S, Warley A, Shaw CE, Miller CC (2012) VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis. Hum Mol Genet 21:1299–1311
-
(2012)
Hum Mol Genet
, vol.21
, pp. 1299-1311
-
-
De Vos, K.J.1
Morotz, G.M.2
Stoica, R.3
Tudor, E.L.4
Lau, K.F.5
Ackerley, S.6
Warley, A.7
Shaw, C.E.8
Miller, C.C.9
-
32
-
-
84875602384
-
D. melanogaster, mitochondria and neurodegeneration: small model organism, big discoveries
-
COI: 1:CAS:528:DC%2BC38Xhtl2gtb%2FP, PID: 22940086
-
Debattisti V, Scorrano L (2013) D. melanogaster, mitochondria and neurodegeneration: small model organism, big discoveries. Mol Cell Neurosci 55:77–86
-
(2013)
Mol Cell Neurosci
, vol.55
, pp. 77-86
-
-
Debattisti, V.1
Scorrano, L.2
-
33
-
-
35448960851
-
Functions and dysfunctions of mitochondrial dynamics
-
COI: 1:CAS:528:DC%2BD2sXhtF2qsLzE, PID: 17928812
-
Detmer SA, Chan DC (2007) Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol 8:870–879
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 870-879
-
-
Detmer, S.A.1
Chan, D.C.2
-
34
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
COI: 1:CAS:528:DyaK2sXmt12rurs%3D, PID: 9302293
-
DiFiglia M, Sapp E, Chase KO, Davies SW, Bates GP, Vonsattel JP, Aronin N (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277:1990–1993
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
35
-
-
84911007903
-
Mitochondrial membrane fluidity is consistently increased in different models of huntington disease: restorative effects of olesoxime
-
COI: 1:CAS:528:DC%2BC2cXktlWnt74%3D, PID: 24633813
-
Eckmann J, Clemens LE, Eckert SH, Hagl S, Yu-Taeger L, Bordet T, Pruss RM, Muller WE, Leuner K, Nguyen HP (2014) Mitochondrial membrane fluidity is consistently increased in different models of huntington disease: restorative effects of olesoxime. Mol Neurobiol 50:107–118
-
(2014)
Mol Neurobiol
, vol.50
, pp. 107-118
-
-
Eckmann, J.1
Clemens, L.E.2
Eckert, S.H.3
Hagl, S.4
Yu-Taeger, L.5
Bordet, T.6
Pruss, R.M.7
Muller, W.E.8
Leuner, K.9
Nguyen, H.P.10
-
36
-
-
84904270185
-
A dynamic interface between vacuoles and mitochondria in yeast
-
COI: 1:CAS:528:DC%2BC2cXhtFGqu7zE, PID: 25026036
-
Elbaz-Alon Y, Rosenfeld-Gur E, Shinder V, Futerman AH, Geiger T, Schuldiner M (2014) A dynamic interface between vacuoles and mitochondria in yeast. Dev Cell 30:95–102
-
(2014)
Dev Cell
, vol.30
, pp. 95-102
-
-
Elbaz-Alon, Y.1
Rosenfeld-Gur, E.2
Shinder, V.3
Futerman, A.H.4
Geiger, T.5
Schuldiner, M.6
-
37
-
-
84871802627
-
Recent advances into the understanding of mitochondrial fission
-
COI: 1:CAS:528:DC%2BC38Xns12qurs%3D, PID: 22580041
-
Elgass K, Pakay J, Ryan MT, Palmer CS (2013) Recent advances into the understanding of mitochondrial fission. Biochim Biophys Acta 1833:150–161
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 150-161
-
-
Elgass, K.1
Pakay, J.2
Ryan, M.T.3
Palmer, C.S.4
-
38
-
-
27644578107
-
Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein
-
COI: 1:CAS:528:DC%2BD2MXht1altrbJ, PID: 16260631
-
Ellis CE, Murphy EJ, Mitchell DC, Golovko MY, Scaglia F, Barcelo-Coblijn GC, Nussbaum RL (2005) Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein. Mol Cell Biol 25:10190–10201
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10190-10201
-
-
Ellis, C.E.1
Murphy, E.J.2
Mitchell, D.C.3
Golovko, M.Y.4
Scaglia, F.5
Barcelo-Coblijn, G.C.6
Nussbaum, R.L.7
-
39
-
-
20444419500
-
A comprehensive classification system for lipids
-
COI: 1:CAS:528:DC%2BD2MXktFaqtLY%3D, PID: 15722563
-
Fahy E, Subramaniam S, Brown HA, Glass CK, Merrill AH Jr, Murphy RC, Raetz CR, Russell DW, Seyama Y, Shaw W, Shimizu T, Spener F, van Meer G, VanNieuwenhze MS, White SH, Witztum JL, Dennis EA (2005) A comprehensive classification system for lipids. J Lipid Res 46:839–861
-
(2005)
J Lipid Res
, vol.46
, pp. 839-861
-
-
Fahy, E.1
Subramaniam, S.2
Brown, H.A.3
Glass, C.K.4
Merrill, A.H.5
Murphy, R.C.6
Raetz, C.R.7
Russell, D.W.8
Seyama, Y.9
Shaw, W.10
Shimizu, T.11
Spener, F.12
van Meer, G.13
VanNieuwenhze, M.S.14
White, S.H.15
Witztum, J.L.16
Dennis, E.A.17
-
40
-
-
66249083144
-
Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity
-
COI: 1:CAS:528:DC%2BD1MXmsFensbg%3D, PID: 19458211
-
Fernandez A, Llacuna L, Fernandez-Checa JC, Colell A (2009) Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity. J Neurosci 29:6394–6405
-
(2009)
J Neurosci
, vol.29
, pp. 6394-6405
-
-
Fernandez, A.1
Llacuna, L.2
Fernandez-Checa, J.C.3
Colell, A.4
-
41
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DyaK2sXmvVKktrk%3D, PID: 9349552
-
Ferrante RJ, Browne SE, Shinobu LA, Bowling AC, Baik MJ, MacGarvey U, Kowall NW, Brown RH, Beal MF (1997) Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem 69:2064–2074
-
(1997)
J Neurochem
, vol.69
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
MacGarvey, U.6
Kowall, N.W.7
Brown, R.H.8
Beal, M.F.9
-
42
-
-
3342951965
-
Lipid rafts mediate the synaptic localization of alpha-synuclein
-
COI: 1:CAS:528:DC%2BD2cXmsVCksb4%3D, PID: 15282274
-
Fortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH (2004) Lipid rafts mediate the synaptic localization of alpha-synuclein. J Neurosci 24:6715–6723
-
(2004)
J Neurosci
, vol.24
, pp. 6715-6723
-
-
Fortin, D.L.1
Troyer, M.D.2
Nakamura, K.3
Kubo, S.4
Anthony, M.D.5
Edwards, R.H.6
-
43
-
-
0030885945
-
Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in parkinson's disease
-
COI: 1:CAS:528:DyaK2sXmsVCksbs%3D, PID: 9326290
-
France-Lanord V, Brugg B, Michel PP, Agid Y, Ruberg M (1997) Mitochondrial free radical signal in ceramide-dependent apoptosis: a putative mechanism for neuronal death in parkinson's disease. J Neurochem 69:1612–1621
-
(1997)
J Neurochem
, vol.69
, pp. 1612-1621
-
-
France-Lanord, V.1
Brugg, B.2
Michel, P.P.3
Agid, Y.4
Ruberg, M.5
-
44
-
-
80054844842
-
ER tubules mark sites of mitochondrial division
-
COI: 1:CAS:528:DC%2BC3MXhtlahsrzM, PID: 21885730
-
Friedman JR, Lackner LL, West M, DiBenedetto JR, Nunnari J, Voeltz GK (2011) ER tubules mark sites of mitochondrial division. Science 334:358–362
-
(2011)
Science
, vol.334
, pp. 358-362
-
-
Friedman, J.R.1
Lackner, L.L.2
West, M.3
DiBenedetto, J.R.4
Nunnari, J.5
Voeltz, G.K.6
-
45
-
-
84925533140
-
Role of mitochondrial lipids in guiding fission and fusion
-
COI: 1:CAS:528:DC%2BC2cXitVKqsLfJ, PID: 25471483
-
Frohman MA (2015) Role of mitochondrial lipids in guiding fission and fusion. J Mol Med 93:263–269
-
(2015)
J Mol Med
, vol.93
, pp. 263-269
-
-
Frohman, M.A.1
-
46
-
-
0030983479
-
Asymmetrical distribution of cardiolipin in yeast inner mitochondrial membrane triggered by carbon catabolite repression
-
COI: 1:CAS:528:DyaK2sXjvFGkurc%3D, PID: 9182727
-
Gallet PF, Petit JM, Maftah A, Zachowski A, Julien R (1997) Asymmetrical distribution of cardiolipin in yeast inner mitochondrial membrane triggered by carbon catabolite repression. Biochem J 324(Pt 2):627–634
-
(1997)
Biochem J
, vol.324
, pp. 627-634
-
-
Gallet, P.F.1
Petit, J.M.2
Maftah, A.3
Zachowski, A.4
Julien, R.5
-
47
-
-
85007354294
-
-
Gao X, Campbell WA, Chaibva M, Jain P, Leslie AE, Frey SL, Legleiter J (2015) Cholesterol modifies huntingtin binding to, disruption of, and aggregation on lipid membranes. Biochemistry (in press)
-
Gao X, Campbell WA, Chaibva M, Jain P, Leslie AE, Frey SL, Legleiter J (2015) Cholesterol modifies huntingtin binding to, disruption of, and aggregation on lipid membranes. Biochemistry (in press)
-
-
-
-
48
-
-
5644225624
-
Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent
-
COI: 1:CAS:528:DC%2BD2cXotVOgs7o%3D, PID: 15292198
-
Gohil VM, Hayes P, Matsuyama S, Schagger H, Schlame M, Greenberg ML (2004) Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent. J Biol Chem 279:42612–42618
-
(2004)
J Biol Chem
, vol.279
, pp. 42612-42618
-
-
Gohil, V.M.1
Hayes, P.2
Matsuyama, S.3
Schagger, H.4
Schlame, M.5
Greenberg, M.L.6
-
49
-
-
0029875381
-
Mitochondrial defect in Huntington's disease caudate nucleus
-
COI: 1:CAS:528:DyaK28XisFyrsbo%3D, PID: 8602759
-
Gu M, Gash M, Mann V, Javoy-Agid F, Cooper J, Schapira A (1996) Mitochondrial defect in Huntington's disease caudate nucleus. Ann Neurol 39:385–389
-
(1996)
Ann Neurol
, vol.39
, pp. 385-389
-
-
Gu, M.1
Gash, M.2
Mann, V.3
Javoy-Agid, F.4
Cooper, J.5
Schapira, A.6
-
50
-
-
0032770167
-
Decrease and structural modifications of phosphatidylethanolamine plasmalogen in the brain with Alzheimer disease
-
Guan Z, Wang Y, Cairns NJ, Lantos PL, Dallner G, Sindelar PJ (1999) Decrease and structural modifications of phosphatidylethanolamine plasmalogen in the brain with Alzheimer disease. J Neuropathol Exp Neurol 58:740-747
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 740-747
-
-
Guan, Z.1
Wang, Y.2
Cairns, N.J.3
Lantos, P.L.4
Dallner, G.5
Sindelar, P.J.6
-
51
-
-
84891410019
-
alpha-Synuclein is localized to mitochondria-associated ER membranes
-
COI: 1:CAS:528:DC%2BC2cXktlOgsA%3D%3D, PID: 24381286
-
Guardia-Laguarta C, Area-Gomez E, Rub C, Liu Y, Magrane J, Becker D, Voos W, Schon EA, Przedborski S (2014) alpha-Synuclein is localized to mitochondria-associated ER membranes. J Neurosci 34:249–259
-
(2014)
J Neurosci
, vol.34
, pp. 249-259
-
-
Guardia-Laguarta, C.1
Area-Gomez, E.2
Rub, C.3
Liu, Y.4
Magrane, J.5
Becker, D.6
Voos, W.7
Schon, E.A.8
Przedborski, S.9
-
52
-
-
85007320497
-
-
Guedes-Dias P, Pinho BR, Soares TR, de Proença J, Duchen MR, Oliveira JM (2015) Mitochondrial dynamics and quality control in Huntington's disease. Neurobiol Dis (in press)
-
Guedes-Dias P, Pinho BR, Soares TR, de Proença J, Duchen MR, Oliveira JM (2015) Mitochondrial dynamics and quality control in Huntington's disease. Neurobiol Dis (in press)
-
-
-
-
53
-
-
0036677303
-
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis
-
COI: 1:CAS:528:DC%2BD38XmsF2htbY%3D, PID: 12358786
-
Han X, Holtzman DM, McKeel DW, Kelley J, Morris JC (2002) Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis. J Neurochem 82:809–818
-
(2002)
J Neurochem
, vol.82
, pp. 809-818
-
-
Han, X.1
Holtzman, D.M.2
McKeel, D.W.3
Kelley, J.4
Morris, J.C.5
-
54
-
-
84878786543
-
Oxidative modification of lipoic acid by HNE in Alzheimer disease brain
-
COI: 1:CAS:528:DC%2BC2cXptFOqtw%3D%3D, PID: 24024140
-
Hardas SS, Sultana R, Clark AM, Beckett TL, Szweda LI, Murphy MP, Butterfield DA (2013) Oxidative modification of lipoic acid by HNE in Alzheimer disease brain. Redox Biol 1:80–85
-
(2013)
Redox Biol
, vol.1
, pp. 80-85
-
-
Hardas, S.S.1
Sultana, R.2
Clark, A.M.3
Beckett, T.L.4
Szweda, L.I.5
Murphy, M.P.6
Butterfield, D.A.7
-
55
-
-
35549006797
-
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca 2 signaling and cell survival
-
COI: 1:CAS:528:DC%2BD2sXhtlWitrzK, PID: 17981125
-
Hayashi T, Su T (2007) Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca 2 signaling and cell survival. Cell 131:596–610
-
(2007)
Cell
, vol.131
, pp. 596-610
-
-
Hayashi, T.1
Su, T.2
-
56
-
-
0037171006
-
Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice
-
COI: 1:CAS:528:DC%2BD38XnsFKkur8%3D, PID: 11930145
-
Hayashi H, Igbavboa U, Hamanaka H, Kobayashi M, Fujita SC, Wood WG, Yanagisawa K (2002) Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice. Neuroreport 13:383–386
-
(2002)
Neuroreport
, vol.13
, pp. 383-386
-
-
Hayashi, H.1
Igbavboa, U.2
Hamanaka, H.3
Kobayashi, M.4
Fujita, S.C.5
Wood, W.G.6
Yanagisawa, K.7
-
57
-
-
61449256510
-
Mitochondrial outer and inner membrane fusion requires a modified carrier protein
-
COI: 1:CAS:528:DC%2BD1MXis1amtrc%3D, PID: 19237599
-
Hoppins S, Horner J, Song C, McCaffery JM, Nunnari J (2009) Mitochondrial outer and inner membrane fusion requires a modified carrier protein. J Cell Biol 184:569–581
-
(2009)
J Cell Biol
, vol.184
, pp. 569-581
-
-
Hoppins, S.1
Horner, J.2
Song, C.3
McCaffery, J.M.4
Nunnari, J.5
-
58
-
-
84861749376
-
Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila
-
COI: 1:CAS:528:DC%2BC38XnsFGisb8%3D, PID: 22398207
-
Humphrey DM, Parsons RB, Ludlow ZN, Riemensperger T, Esposito G, Verstreken P, Jacobs HT, Birman S, Hirth F (2012) Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila. Hum Mol Genet 21:2698–2712
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2698-2712
-
-
Humphrey, D.M.1
Parsons, R.B.2
Ludlow, Z.N.3
Riemensperger, T.4
Esposito, G.5
Verstreken, P.6
Jacobs, H.T.7
Birman, S.8
Hirth, F.9
-
59
-
-
70350558667
-
Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway
-
COI: 1:CAS:528:DC%2BD1MXhtlymtrzP, PID: 19625658
-
Huttunen HJ, Peach C, Bhattacharyya R, Barren C, Pettingell W, Hutter-Paier B, Windisch M, Berezovska O, Kovacs DM (2009) Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway. FASEB J 23:3819–3828
-
(2009)
FASEB J
, vol.23
, pp. 3819-3828
-
-
Huttunen, H.J.1
Peach, C.2
Bhattacharyya, R.3
Barren, C.4
Pettingell, W.5
Hutter-Paier, B.6
Windisch, M.7
Berezovska, O.8
Kovacs, D.M.9
-
60
-
-
13444287961
-
Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity
-
COI: 1:CAS:528:DC%2BD2MXhtFertLg%3D, PID: 15572413
-
Ishihara N, Eura Y, Mihara K (2004) Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity. J Cell Sci 117:6535–6546
-
(2004)
J Cell Sci
, vol.117
, pp. 6535-6546
-
-
Ishihara, N.1
Eura, Y.2
Mihara, K.3
-
61
-
-
77955961922
-
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS
-
COI: 1:CAS:528:DC%2BC3cXhtV2gtb3L, PID: 20797535
-
Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan-Barmatz V, Cleveland DW (2010) Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS. Neuron 67:575–587
-
(2010)
Neuron
, vol.67
, pp. 575-587
-
-
Israelson, A.1
Arbel, N.2
Da Cruz, S.3
Ilieva, H.4
Yamanaka, K.5
Shoshan-Barmatz, V.6
Cleveland, D.W.7
-
62
-
-
84872833228
-
Mitochondrial dynamics in neurodegeneration
-
COI: 1:CAS:528:DC%2BC3sXhs1ektbs%3D, PID: 23159640
-
Itoh K, Nakamura K, Iijima M, Sesaki H (2013) Mitochondrial dynamics in neurodegeneration. Trends Cell Biol 23:64–71
-
(2013)
Trends Cell Biol
, vol.23
, pp. 64-71
-
-
Itoh, K.1
Nakamura, K.2
Iijima, M.3
Sesaki, H.4
-
63
-
-
69549103145
-
Recent advances in our understanding of neurodegeneration
-
COI: 1:CAS:528:DC%2BD1MXhtVeqs7jM, PID: 19707851
-
Jellinger KA (2009) Recent advances in our understanding of neurodegeneration. J Neural Transm 116:1111–1162
-
(2009)
J Neural Transm
, vol.116
, pp. 1111-1162
-
-
Jellinger, K.A.1
-
64
-
-
84887486172
-
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
-
COI: 1:CAS:528:DC%2BC2cXhtVyiurzF, PID: 24149988
-
Jin SM, Youle RJ (2013) The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 9:1750–1757
-
(2013)
Autophagy
, vol.9
, pp. 1750-1757
-
-
Jin, S.M.1
Youle, R.J.2
-
65
-
-
84861217461
-
Cardiolipin and mitochondrial phosphatidylethanolamine have overlapping functions in mitochondrial fusion in Saccharomyces cerevisiae
-
COI: 1:CAS:528:DC%2BC38XntFSntLs%3D, PID: 22433850
-
Joshi AS, Thompson MN, Fei N, Hüttemann M, Greenberg ML (2012) Cardiolipin and mitochondrial phosphatidylethanolamine have overlapping functions in mitochondrial fusion in Saccharomyces cerevisiae. J Biol Chem 287:17589–17597
-
(2012)
J Biol Chem
, vol.287
, pp. 17589-17597
-
-
Joshi, A.S.1
Thompson, M.N.2
Fei, N.3
Hüttemann, M.4
Greenberg, M.L.5
-
66
-
-
33947577504
-
Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer’s disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer’s disease?
-
COI: 1:CAS:528:DC%2BD2sXjtlymtL4%3D, PID: 17342407
-
Katsel P, Li C, Haroutunian V (2007) Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer’s disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer’s disease? Neurochem Res 32:845–856
-
(2007)
Neurochem Res
, vol.32
, pp. 845-856
-
-
Katsel, P.1
Li, C.2
Haroutunian, V.3
-
67
-
-
84954164606
-
A signaling lipid associated with alzheimer’s disease promotes mitochondrial dysfunction
-
COI: 1:CAS:528:DC%2BC28Xos1Glsw%3D%3D, PID: 26757638
-
Kennedy MA, Moffat TC, Gable K, Ganesan S, Niewola-Staszkowska K, Johnston A, Nislow C, Giaever G, Harris LJ, Loewith R (2016) A signaling lipid associated with alzheimer’s disease promotes mitochondrial dysfunction. Sci Rep 6:19332
-
(2016)
Sci Rep
, vol.6
, pp. 19332
-
-
Kennedy, M.A.1
Moffat, T.C.2
Gable, K.3
Ganesan, S.4
Niewola-Staszkowska, K.5
Johnston, A.6
Nislow, C.7
Giaever, G.8
Harris, L.J.9
Loewith, R.10
-
68
-
-
84960119610
-
Mitochondrial dysfunction and lipid peroxidation in rat frontal cortex by chronic NMDA administration can be partially prevented by lithium treatment
-
PID: 26894301
-
Kim HK, Isaacs-Trepanier C, Elmi N, Rapoport SI, Andreazza AC (2016) Mitochondrial dysfunction and lipid peroxidation in rat frontal cortex by chronic NMDA administration can be partially prevented by lithium treatment. J Psychiatr Res 76:59–65
-
(2016)
J Psychiatr Res
, vol.76
, pp. 59-65
-
-
Kim, H.K.1
Isaacs-Trepanier, C.2
Elmi, N.3
Rapoport, S.I.4
Andreazza, A.C.5
-
69
-
-
36048969412
-
Isc1 regulates sphingolipid metabolism in yeast mitochondria
-
COI: 1:CAS:528:DC%2BD2sXht12gu77F, PID: 17880915
-
Kitagaki H, Cowart LA, Matmati N, de Avalos SV, Novgorodov SA, Zeidan YH, Bielawski J, Obeid LM, Hannun YA (2007) Isc1 regulates sphingolipid metabolism in yeast mitochondria. Biochim Biophys Acta 1768:2849–2861
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 2849-2861
-
-
Kitagaki, H.1
Cowart, L.A.2
Matmati, N.3
de Avalos, S.V.4
Novgorodov, S.A.5
Zeidan, Y.H.6
Bielawski, J.7
Obeid, L.M.8
Hannun, Y.A.9
-
70
-
-
84864267876
-
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
-
PID: 22724072
-
Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, Muqit MM (2012) PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol 2:120080
-
(2012)
Open Biol
, vol.2
, pp. 120080
-
-
Kondapalli, C.1
Kazlauskaite, A.2
Zhang, N.3
Woodroof, H.I.4
Campbell, D.G.5
Gourlay, R.6
Burchell, L.7
Walden, H.8
Macartney, T.J.9
Deak, M.10
Knebel, A.11
Alessi, D.R.12
Muqit, M.M.13
-
71
-
-
26444530575
-
Ceramide activates a mitochondrial p38 mitogen-activated protein kinase: a potential mechanism for loss of mitochondrial transmembrane potential and apoptosis
-
COI: 1:CAS:528:DC%2BD2MXhtVentr3J, PID: 16180087
-
Kong JY, Klassen SS, Rabkin SW (2005) Ceramide activates a mitochondrial p38 mitogen-activated protein kinase: a potential mechanism for loss of mitochondrial transmembrane potential and apoptosis. Mol Cell Biochem 278:39–51
-
(2005)
Mol Cell Biochem
, vol.278
, pp. 39-51
-
-
Kong, J.Y.1
Klassen, S.S.2
Rabkin, S.W.3
-
72
-
-
77955361329
-
Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria
-
COI: 1:CAS:528:DC%2BC3cXpvFSlsbo%3D, PID: 20554689
-
Kopec KO, Alva V, Lupas AN (2010) Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria. Bioinformatics 26:1927–1931
-
(2010)
Bioinformatics
, vol.26
, pp. 1927-1931
-
-
Kopec, K.O.1
Alva, V.2
Lupas, A.N.3
-
73
-
-
67749122635
-
An ER-mitochondria tethering complex revealed by a synthetic biology screen
-
COI: 1:CAS:528:DC%2BD1MXovVCgt7c%3D, PID: 19556461
-
Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325:477–481
-
(2009)
Science
, vol.325
, pp. 477-481
-
-
Kornmann, B.1
Currie, E.2
Collins, S.R.3
Schuldiner, M.4
Nunnari, J.5
Weissman, J.S.6
Walter, P.7
-
74
-
-
80052172908
-
The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections
-
COI: 1:CAS:528:DC%2BC3MXhtFaqt73F, PID: 21825164
-
Kornmann B, Osman C, Walter P (2011) The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc Natl Acad Sci U S A 108:14151–14156
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 14151-14156
-
-
Kornmann, B.1
Osman, C.2
Walter, P.3
-
75
-
-
84872769447
-
An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2
-
COI: 1:CAS:528:DC%2BC3sXhtFyntb8%3D, PID: 23349293
-
Korobova F, Ramabhadran V, Higgs HN (2013) An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2. Science 339:464–467
-
(2013)
Science
, vol.339
, pp. 464-467
-
-
Korobova, F.1
Ramabhadran, V.2
Higgs, H.N.3
-
76
-
-
84894363564
-
A role for myosin II in mammalian mitochondrial fission
-
COI: 1:CAS:528:DC%2BC2cXhs1ajtLs%3D, PID: 24485837
-
Korobova F, Gauvin TJ, Higgs HN (2014) A role for myosin II in mammalian mitochondrial fission. Curr Biol 24:409–414
-
(2014)
Curr Biol
, vol.24
, pp. 409-414
-
-
Korobova, F.1
Gauvin, T.J.2
Higgs, H.N.3
-
77
-
-
0032731637
-
ALS-linked Cu/Zn–SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis
-
COI: 1:CAS:528:DyaK1MXotVOktL0%3D, PID: 10630188
-
Kruman II, Pedersen WA, Springer JE, Mattson MP (1999) ALS-linked Cu/Zn–SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis. Exp Neurol 160:28–39
-
(1999)
Exp Neurol
, vol.160
, pp. 28-39
-
-
Kruman, I.I.1
Pedersen, W.A.2
Springer, J.E.3
Mattson, M.P.4
-
78
-
-
84941739003
-
The role of mitochondrial dysfunction in age-related diseases
-
COI: 1:CAS:528:DC%2BC2MXhtVWrtLzF, PID: 26050974
-
Lane RK, Hilsabeck T, Rea SL (2015) The role of mitochondrial dysfunction in age-related diseases. Biochim Biophys Acta 1847:1387–1400
-
(2015)
Biochim Biophys Acta
, vol.1847
, pp. 1387-1400
-
-
Lane, R.K.1
Hilsabeck, T.2
Rea, S.L.3
-
79
-
-
33644905848
-
Diverse membrane-associated proteins contain a novel SMP domain
-
COI: 1:CAS:528:DC%2BD28XhsFOmurw%3D, PID: 16449791
-
Lee I, Hong W (2006) Diverse membrane-associated proteins contain a novel SMP domain. FASEB J 20:202–206
-
(2006)
FASEB J
, vol.20
, pp. 202-206
-
-
Lee, I.1
Hong, W.2
-
80
-
-
0347122965
-
Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
-
COI: 1:CAS:528:DC%2BD2cXjs1Cksw%3D%3D, PID: 14709545
-
Lee JT, Xu J, Lee JM, Ku G, Han X, Yang DI, Chen S, Hsu CY (2004) Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway. J Cell Biol 164:123–131
-
(2004)
J Cell Biol
, vol.164
, pp. 123-131
-
-
Lee, J.T.1
Xu, J.2
Lee, J.M.3
Ku, G.4
Han, X.5
Yang, D.I.6
Chen, S.7
Hsu, C.Y.8
-
81
-
-
79954575043
-
Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington’s disease mice
-
COI: 1:CAS:528:DC%2BC3MXjsVWmtbY%3D, PID: 21161248
-
Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H (2011a) Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington’s disease mice. Acta Neuropathol 121:487–498
-
(2011)
Acta Neuropathol
, vol.121
, pp. 487-498
-
-
Lee, J.1
Kosaras, B.2
Del Signore, S.J.3
Cormier, K.4
McKee, A.5
Ratan, R.R.6
Kowall, N.W.7
Ryu, H.8
-
82
-
-
79251550710
-
Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease
-
COI: 1:CAS:528:DC%2BC3MXhtFWgurY%3D, PID: 21264320
-
Lee YJ, Wang S, Slone SR, Yacoubian TA, Witt SN (2011b) Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. PLoS ONE 6:e15946
-
(2011)
PLoS ONE
, vol.6
-
-
Lee, Y.J.1
Wang, S.2
Slone, S.R.3
Yacoubian, T.A.4
Witt, S.N.5
-
83
-
-
84930046200
-
The impairment of cholesterol metabolism in Huntington disease
-
COI: 1:CAS:528:DC%2BC2MXht1Krsrc%3D, PID: 25596342
-
Leoni V, Caccia C (2015) The impairment of cholesterol metabolism in Huntington disease. Biochim Biophys Acta 1851:1095–1105
-
(2015)
Biochim Biophys Acta
, vol.1851
, pp. 1095-1105
-
-
Leoni, V.1
Caccia, C.2
-
84
-
-
84941944128
-
Mitochondria, autophagy and age-associated neurodegenerative diseases: new insights into a complex interplay
-
COI: 1:CAS:528:DC%2BC2MXns1Gqs74%3D, PID: 25917894
-
Lionaki E, Markaki M, Palikaras K, Tavernarakis N (2015) Mitochondria, autophagy and age-associated neurodegenerative diseases: new insights into a complex interplay. Biochim Biophys Acta 1847:1412–1423
-
(2015)
Biochim Biophys Acta
, vol.1847
, pp. 1412-1423
-
-
Lionaki, E.1
Markaki, M.2
Palikaras, K.3
Tavernarakis, N.4
-
85
-
-
84874639591
-
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission
-
COI: 1:CAS:528:DC%2BC3sXjvVajsLo%3D, PID: 23283981
-
Loson OC, Song Z, Chen H, Chan DC (2013) Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol Biol Cell 24:659–667
-
(2013)
Mol Biol Cell
, vol.24
, pp. 659-667
-
-
Loson, O.C.1
Song, Z.2
Chen, H.3
Chan, D.C.4
-
86
-
-
85007319135
-
-
Maglioni S, Ventura N (2016) C. elegans as a model organism for human mitochondrial associated disorders. Mitochondrion (in press)
-
Maglioni S, Ventura N (2016) C. elegans as a model organism for human mitochondrial associated disorders. Mitochondrion (in press)
-
-
-
-
87
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
-
COI: 1:CAS:528:DC%2BC3MXntlGls7g%3D, PID: 21459773
-
Manczak M, Calkins MJ, Reddy PH (2011) Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. Hum Mol Genet 20:2495–2509
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
88
-
-
84869234106
-
Sigma-1 receptor at the mitochondrial-associated endoplasmic reticulum membrane is responsible for mitochondrial metabolic regulation
-
COI: 1:CAS:528:DC%2BC38Xhslyjs7%2FP, PID: 22923735
-
Marriott KS, Prasad M, Thapliyal V, Bose HS (2012) Sigma-1 receptor at the mitochondrial-associated endoplasmic reticulum membrane is responsible for mitochondrial metabolic regulation. J Pharmacol Exp Ther 343:578–586
-
(2012)
J Pharmacol Exp Ther
, vol.343
, pp. 578-586
-
-
Marriott, K.S.1
Prasad, M.2
Thapliyal, V.3
Bose, H.S.4
-
89
-
-
77955358107
-
Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3cXhtlGjurbI, PID: 20721828
-
Martin LJ (2010) Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis. IDrugs 13:568–580
-
(2010)
IDrugs
, vol.13
, pp. 568-580
-
-
Martin, L.J.1
-
90
-
-
30644471051
-
Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
COI: 1:CAS:528:DC%2BD28XmtV2gtw%3D%3D, PID: 16399671
-
Martin LJ, Pan Y, Price AC, Sterling W, Copeland NG, Jenkins NA, Price DL, Lee MK (2006) Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. J Neurosci 26:41–50
-
(2006)
J Neurosci
, vol.26
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
91
-
-
84897863239
-
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
-
COI: 1:CAS:528:DC%2BC2cXhtV2iu7jM, PID: 24446486
-
McLelland GL, Soubannier V, Chen CX, McBride HM, Fon EA (2014) Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J 33:282–295
-
(2014)
EMBO J
, vol.33
, pp. 282-295
-
-
McLelland, G.L.1
Soubannier, V.2
Chen, C.X.3
McBride, H.M.4
Fon, E.A.5
-
92
-
-
78650987611
-
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission
-
COI: 1:CAS:528:DC%2BC3cXhsFyisLbP, PID: 21170049
-
Mears JA, Lackner LL, Fang S, Ingerman E, Nunnari J, Hinshaw JE (2011) Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission. Nat Struct Mol Biol 18:20–26
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 20-26
-
-
Mears, J.A.1
Lackner, L.L.2
Fang, S.3
Ingerman, E.4
Nunnari, J.5
Hinshaw, J.E.6
-
93
-
-
0242593934
-
Evidence for a two membrane-spanning autonomous mitochondrial DNA replisome
-
COI: 1:CAS:528:DC%2BD3sXovFCnurs%3D, PID: 14597773
-
Meeusen S, Nunnari J (2003) Evidence for a two membrane-spanning autonomous mitochondrial DNA replisome. J Cell Biol 163:503–510
-
(2003)
J Cell Biol
, vol.163
, pp. 503-510
-
-
Meeusen, S.1
Nunnari, J.2
-
94
-
-
4344640696
-
The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane
-
COI: 1:CAS:528:DC%2BD2cXntVCiu7o%3D, PID: 15239954
-
Meisinger C, Rissler M, Chacinska A, Szklarz LKS, Milenkovic D, Kozjak V, Schönfisch B, Lohaus C, Meyer HE, Yaffe MP (2004) The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane. Dev Cell 7:61–71
-
(2004)
Dev Cell
, vol.7
, pp. 61-71
-
-
Meisinger, C.1
Rissler, M.2
Chacinska, A.3
Szklarz, L.K.S.4
Milenkovic, D.5
Kozjak, V.6
Schönfisch, B.7
Lohaus, C.8
Meyer, H.E.9
Yaffe, M.P.10
-
95
-
-
84884264199
-
Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study
-
COI: 1:CAS:528:DC%2BC3sXhsFeitb7I, PID: 24058461
-
Mielke MM, Maetzler W, Haughey NJ, Bandaru VV, Savica R, Deuschle C, Gasser T, Hauser A, Gräber-Sultan S, Schleicher E (2013) Plasma ceramide and glucosylceramide metabolism is altered in sporadic Parkinson's disease and associated with cognitive impairment: a pilot study. PLoS ONE 8:e73094
-
(2013)
PLoS ONE
, vol.8
-
-
Mielke, M.M.1
Maetzler, W.2
Haughey, N.J.3
Bandaru, V.V.4
Savica, R.5
Deuschle, C.6
Gasser, T.7
Hauser, A.8
Gräber-Sultan, S.9
Schleicher, E.10
-
96
-
-
84884316964
-
Mitochondrial membrane lipid remodeling in pathophysiology: a new target for diet and therapeutic interventions
-
COI: 1:CAS:528:DC%2BC3sXhslGls7bP, PID: 23827885
-
Monteiro JP, Oliveira PJ, Jurado AS (2013) Mitochondrial membrane lipid remodeling in pathophysiology: a new target for diet and therapeutic interventions. Prog Lipid Res 52:513–528
-
(2013)
Prog Lipid Res
, vol.52
, pp. 513-528
-
-
Monteiro, J.P.1
Oliveira, P.J.2
Jurado, A.S.3
-
97
-
-
0031028437
-
Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4
-
COI: 1:CAS:528:DyaK2sXhtlSgsbw%3D, PID: 9033259
-
Montine KS, Olson SJ, Amarnath V, Whetsell WO Jr, Graham DG, Montine TJ (1997) Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of APOE4. Am J Pathol 150:437–443
-
(1997)
Am J Pathol
, vol.150
, pp. 437-443
-
-
Montine, K.S.1
Olson, S.J.2
Amarnath, V.3
Whetsell, W.O.4
Graham, D.G.5
Montine, T.J.6
-
98
-
-
84894528843
-
Reduced glucocerebrosidase is associated with increased alpha-synuclein in sporadic Parkinson's disease
-
PID: 24477431
-
Murphy KE, Gysbers AM, Abbott SK, Tayebi N, Kim WS, Sidransky E, Cooper A, Garner B, Halliday GM (2014) Reduced glucocerebrosidase is associated with increased alpha-synuclein in sporadic Parkinson's disease. Brain 137:834–848
-
(2014)
Brain
, vol.137
, pp. 834-848
-
-
Murphy, K.E.1
Gysbers, A.M.2
Abbott, S.K.3
Tayebi, N.4
Kim, W.S.5
Sidransky, E.6
Cooper, A.7
Garner, B.8
Halliday, G.M.9
-
99
-
-
79957974579
-
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein
-
COI: 1:CAS:528:DC%2BC3MXmvFCgtbY%3D, PID: 21489994
-
Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH (2011) Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein. J Biol Chem 286:20710–20726
-
(2011)
J Biol Chem
, vol.286
, pp. 20710-20726
-
-
Nakamura, K.1
Nemani, V.M.2
Azarbal, F.3
Skibinski, G.4
Levy, J.M.5
Egami, K.6
Munishkina, L.7
Zhang, J.8
Gardner, B.9
Wakabayashi, J.10
Sesaki, H.11
Cheng, Y.12
Finkbeiner, S.13
Nussbaum, R.L.14
Masliah, E.15
Edwards, R.H.16
-
100
-
-
0030894380
-
Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform
-
COI: 1:CAS:528:DyaK2sXhvVOnt7Y%3D, PID: 9045652
-
Naslavsky N, Stein R, Yanai A, Friedlander G, Taraboulos A (1997) Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform. J Biol Chem 272:6324–6331
-
(1997)
J Biol Chem
, vol.272
, pp. 6324-6331
-
-
Naslavsky, N.1
Stein, R.2
Yanai, A.3
Friedlander, G.4
Taraboulos, A.5
-
101
-
-
84860916316
-
Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance
-
COI: 1:CAS:528:DC%2BC38XoslClt7Y%3D, PID: 22409400
-
Nguyen TT, Lewandowska A, Choi J, Markgraf DF, Junker M, Bilgin M, Ejsing CS, Voelker DR, Rapoport TA, Shaw JM (2012) Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic 13:880–890
-
(2012)
Traffic
, vol.13
, pp. 880-890
-
-
Nguyen, T.T.1
Lewandowska, A.2
Choi, J.3
Markgraf, D.F.4
Junker, M.5
Bilgin, M.6
Ejsing, C.S.7
Voelker, D.R.8
Rapoport, T.A.9
Shaw, J.M.10
-
102
-
-
6344257200
-
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD2cXptVSns7k%3D, PID: 15372378
-
Nishimura AL, Mitne-Neto M, Silva HC, Richieri-Costa A, Middleton S, Cascio D, Kok F, Oliveira JR, Gillingwater T, Webb J (2004) A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet 75:822–831
-
(2004)
Am J Hum Genet
, vol.75
, pp. 822-831
-
-
Nishimura, A.L.1
Mitne-Neto, M.2
Silva, H.C.3
Richieri-Costa, A.4
Middleton, S.5
Cascio, D.6
Kok, F.7
Oliveira, J.R.8
Gillingwater, T.9
Webb, J.10
-
103
-
-
84882254367
-
The role of autophagy in neurodegenerative disease
-
COI: 1:CAS:528:DC%2BC3sXht1WqsrvI, PID: 23921753
-
Nixon RA (2013) The role of autophagy in neurodegenerative disease. Nat Med 19:983–997
-
(2013)
Nat Med
, vol.19
, pp. 983-997
-
-
Nixon, R.A.1
-
104
-
-
79960117964
-
Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA
-
COI: 1:CAS:528:DC%2BC3MXosFGmtbk%3D, PID: 21613224
-
Novgorodov SA, Wu BX, Gudz TI, Bielawski J, Ovchinnikova TV, Hannun YA, Obeid LM (2011) Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA. J Biol Chem 286:25352–25362
-
(2011)
J Biol Chem
, vol.286
, pp. 25352-25362
-
-
Novgorodov, S.A.1
Wu, B.X.2
Gudz, T.I.3
Bielawski, J.4
Ovchinnikova, T.V.5
Hannun, Y.A.6
Obeid, L.M.7
-
105
-
-
27544466847
-
Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes
-
COI: 1:CAS:528:DC%2BD28Xlt1Wqsg%3D%3D, PID: 16285870
-
Okamoto K, Shaw JM (2005) Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu Rev Genet 39:503–536
-
(2005)
Annu Rev Genet
, vol.39
, pp. 503-536
-
-
Okamoto, K.1
Shaw, J.M.2
-
106
-
-
78650727185
-
Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling
-
PID: 21297908
-
Packer L, Cadenas E (2010) Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. J Clin Biochem Nutr 48:26–32
-
(2010)
J Clin Biochem Nutr
, vol.48
, pp. 26-32
-
-
Packer, L.1
Cadenas, E.2
-
107
-
-
2442481789
-
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
-
COI: 1:CAS:528:DC%2BD2cXjsVKmsrc%3D, PID: 14985362
-
Palacino JJ, Sagi D, Goldberg MS, Krauss S, Motz C, Wacker M, Klose J, Shen J (2004) Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. J Biol Chem 279:18614–18622
-
(2004)
J Biol Chem
, vol.279
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
108
-
-
0025272543
-
Age-related changes in the activity of the pyruvate carrier and in the lipid composition in rat-heart mitochondria
-
COI: 1:CAS:528:DyaK3cXitFCgsLg%3D, PID: 2317482
-
Paradies G, Ruggiero FM (1990) Age-related changes in the activity of the pyruvate carrier and in the lipid composition in rat-heart mitochondria. Biochim Biophys Acta 1016:207–212
-
(1990)
Biochim Biophys Acta
, vol.1016
, pp. 207-212
-
-
Paradies, G.1
Ruggiero, F.M.2
-
109
-
-
38849095253
-
Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis
-
COI: 1:CAS:528:DC%2BD1cXis12ku7Y%3D, PID: 18006463
-
Parra V, Eisner V, Chiong M, Criollo A, Moraga F, Garcia A, Hartel S, Jaimovich E, Zorzano A, Hidalgo C, Lavandero S (2008) Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovasc Res 77:387–397
-
(2008)
Cardiovasc Res
, vol.77
, pp. 387-397
-
-
Parra, V.1
Eisner, V.2
Chiong, M.3
Criollo, A.4
Moraga, F.5
Garcia, A.6
Hartel, S.7
Jaimovich, E.8
Zorzano, A.9
Hidalgo, C.10
Lavandero, S.11
-
110
-
-
0031768026
-
Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients
-
COI: 1:CAS:528:DyaK1cXnsFChtr8%3D, PID: 9818940
-
Pedersen WA, Fu W, Keller JN, Markesbery WR, Appel S, Smith RG, Kasarskis E, Mattson MP (1998) Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients. Ann Neurol 44:819–824
-
(1998)
Ann Neurol
, vol.44
, pp. 819-824
-
-
Pedersen, W.A.1
Fu, W.2
Keller, J.N.3
Markesbery, W.R.4
Appel, S.5
Smith, R.G.6
Kasarskis, E.7
Mattson, M.P.8
-
111
-
-
14644400490
-
Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice-A model of familial amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD2MXitVCnsbw%3D, PID: 15749392
-
Perluigi M, Poon HF, Hensley K, Pierce WM, Klein JB, Calabrese V, De Marco C, Butterfield DA (2005) Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice-A model of familial amyotrophic lateral sclerosis. Free Radic Biol Med 38:960–968
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 960-968
-
-
Perluigi, M.1
Poon, H.F.2
Hensley, K.3
Pierce, W.M.4
Klein, J.B.5
Calabrese, V.6
De Marco, C.7
Butterfield, D.A.8
-
112
-
-
70350089195
-
Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: role of lipid peroxidation in Alzheimer's disease pathogenesis
-
COI: 1:CAS:528:DC%2BD1MXnslylu74%3D, PID: 20333275
-
Perluigi M, Sultana R, Cenini G, Di Domenico F, Memo M, Pierce WM, Coccia R, Butterfield DA (2009) Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer's disease: role of lipid peroxidation in Alzheimer's disease pathogenesis. Proteomics Clin Appl 3:682–693
-
(2009)
Proteomics Clin Appl
, vol.3
, pp. 682-693
-
-
Perluigi, M.1
Sultana, R.2
Cenini, G.3
Di Domenico, F.4
Memo, M.5
Pierce, W.M.6
Coccia, R.7
Butterfield, D.A.8
-
113
-
-
0034602271
-
Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis
-
COI: 1:CAS:528:DC%2BD3cXotFWlsLc%3D, PID: 10952980
-
Perrin RJ, Woods WS, Clayton DF, George JM (2000) Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. J Biol Chem 275:34393–34398
-
(2000)
J Biol Chem
, vol.275
, pp. 34393-34398
-
-
Perrin, R.J.1
Woods, W.S.2
Clayton, D.F.3
George, J.M.4
-
114
-
-
0035861885
-
Reactive oxygen species generated from the mitochondrial electron transport chain induce cytochrome c dissociation from beef-heart submitochondrial particles via cardiolipin peroxidation. Possible role in the apoptosis
-
COI: 1:CAS:528:DC%2BD3MXptFymurk%3D, PID: 11749969
-
Petrosillo G, Ruggiero FM, Pistolese M, Paradies G (2001) Reactive oxygen species generated from the mitochondrial electron transport chain induce cytochrome c dissociation from beef-heart submitochondrial particles via cardiolipin peroxidation. Possible role in the apoptosis. FEBS Lett 509:435–438
-
(2001)
FEBS Lett
, vol.509
, pp. 435-438
-
-
Petrosillo, G.1
Ruggiero, F.M.2
Pistolese, M.3
Paradies, G.4
-
115
-
-
0034795651
-
Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid β-peptide
-
COI: 1:CAS:528:DC%2BD3MXnslejuro%3D, PID: 11584272
-
Puglielli L, Konopka G, Pack-Chung E, Ingano LAM, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM (2001) Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid β-peptide. Nat Cell Biol 3:905–912
-
(2001)
Nat Cell Biol
, vol.3
, pp. 905-912
-
-
Puglielli, L.1
Konopka, G.2
Pack-Chung, E.3
Ingano, L.A.M.4
Berezovska, O.5
Hyman, B.T.6
Chang, T.Y.7
Tanzi, R.E.8
Kovacs, D.M.9
-
116
-
-
0037490159
-
Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis
-
COI: 1:CAS:528:DC%2BD3sXktVaqtrc%3D, PID: 12649271
-
Puglielli L, Ellis BC, Saunders AJ, Kovacs DM (2003) Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis. J Biol Chem 278:19777–19783
-
(2003)
J Biol Chem
, vol.278
, pp. 19777-19783
-
-
Puglielli, L.1
Ellis, B.C.2
Saunders, A.J.3
Kovacs, D.M.4
-
117
-
-
34247130917
-
Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation
-
COI: 1:CAS:528:DC%2BD2sXhvVahsr8%3D, PID: 17189262
-
Qin Z, Hu D, Han S, Reaney SH, Di Monte DA, Fink AL (2007) Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation. J Biol Chem 282:5862–5870
-
(2007)
J Biol Chem
, vol.282
, pp. 5862-5870
-
-
Qin, Z.1
Hu, D.2
Han, S.3
Reaney, S.H.4
Di Monte, D.A.5
Fink, A.L.6
-
118
-
-
40849120274
-
Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease
-
COI: 1:CAS:528:DC%2BD1cXjs1Gruro%3D, PID: 18325775
-
Reed T, Perluigi M, Sultana R, Pierce WM, Klein JB, Turner DM, Coccia R, Markesbery WR, Butterfield DA (2008) Redox proteomic identification of 4-hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease. Neurobiol Dis 30:107–120
-
(2008)
Neurobiol Dis
, vol.30
, pp. 107-120
-
-
Reed, T.1
Perluigi, M.2
Sultana, R.3
Pierce, W.M.4
Klein, J.B.5
Turner, D.M.6
Coccia, R.7
Markesbery, W.R.8
Butterfield, D.A.9
-
119
-
-
67349279818
-
Proteomic identification of HNE-bound proteins in early Alzheimer disease: insights into the role of lipid peroxidation in the progression of AD
-
COI: 1:CAS:528:DC%2BD1MXmtlOqsb8%3D, PID: 19374891
-
Reed TT, Pierce WM, Markesbery WR, Butterfield DA (2009) Proteomic identification of HNE-bound proteins in early Alzheimer disease: insights into the role of lipid peroxidation in the progression of AD. Brain Res 1274:66–76
-
(2009)
Brain Res
, vol.1274
, pp. 66-76
-
-
Reed, T.T.1
Pierce, W.M.2
Markesbery, W.R.3
Butterfield, D.A.4
-
120
-
-
84878562770
-
Autophagic processes in yeast: mechanism, machinery and regulation
-
COI: 1:CAS:528:DC%2BC3sXhtFCmsbvL, PID: 23733851
-
Reggiori F, Klionsky DJ (2013) Autophagic processes in yeast: mechanism, machinery and regulation. Genetics 194:341–361
-
(2013)
Genetics
, vol.194
, pp. 341-361
-
-
Reggiori, F.1
Klionsky, D.J.2
-
121
-
-
84866728707
-
Endoplasmic reticulum–mitochondria contacts: function of the junction
-
COI: 1:CAS:528:DC%2BC38XhtlKrsbbM, PID: 22992592
-
Rowland AA, Voeltz GK (2012) Endoplasmic reticulum–mitochondria contacts: function of the junction. Nat Rev Mol Cell Biol 13:607–625
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 607-625
-
-
Rowland, A.A.1
Voeltz, G.K.2
-
122
-
-
84922988247
-
Mitochondrial division and fusion in metabolism
-
COI: 1:CAS:528:DC%2BC2MXisl2qsbc%3D, PID: 25703628
-
Roy M, Reddy PH, Iijima M, Sesaki H (2015) Mitochondrial division and fusion in metabolism. Curr Opin Cell Biol 33:111–118
-
(2015)
Curr Opin Cell Biol
, vol.33
, pp. 111-118
-
-
Roy, M.1
Reddy, P.H.2
Iijima, M.3
Sesaki, H.4
-
123
-
-
79952180064
-
Lipid rafts: linking Alzheimer's amyloid-beta production, aggregation, and toxicity at neuronal membranes
-
PID: 21234417
-
Rushworth JV, Hooper NM (2010) Lipid rafts: linking Alzheimer's amyloid-beta production, aggregation, and toxicity at neuronal membranes. Int J Alzheimers Dis 2011:603052
-
(2010)
Int J Alzheimers Dis
, vol.2011
, pp. 603052
-
-
Rushworth, J.V.1
Hooper, N.M.2
-
124
-
-
0027973135
-
A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins
-
COI: 1:STN:280:DyaK2M%2FltVCqsQ%3D%3D, PID: 7961664
-
Rusinol AE, Cui Z, Chen MH, Vance JE (1994) A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins. J Biol Chem 269:27494–27502
-
(1994)
J Biol Chem
, vol.269
, pp. 27494-27502
-
-
Rusinol, A.E.1
Cui, Z.2
Chen, M.H.3
Vance, J.E.4
-
125
-
-
84925298301
-
Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
-
COI: 1:CAS:528:DC%2BC2MXjtFGmsLw%3D, PID: 25757399
-
Ryan BJ, Hoek S, Fon EA, Wade-Martins R (2015) Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease. Trends Biochem Sci 40:200–210
-
(2015)
Trends Biochem Sci
, vol.40
, pp. 200-210
-
-
Ryan, B.J.1
Hoek, S.2
Fon, E.A.3
Wade-Martins, R.4
-
126
-
-
84876296881
-
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
-
COI: 1:CAS:528:DC%2BC3sXkvFOqs7k%3D, PID: 23503661
-
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW (2013) Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature 496:372–376
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
Gygi, S.P.6
Harper, J.W.7
-
127
-
-
16044373524
-
Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
COI: 1:CAS:528:DyaK28XkslGiu7g%3D, PID: 8705854
-
Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, Bird T, Hardy J, Hutton M, Kukull W (1996) Secreted amyloid β-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med 2:864–870
-
(1996)
Nat Med
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
-
128
-
-
84875599536
-
Mitochondria-associated ER membranes in Alzheimer disease
-
COI: 1:CAS:528:DC%2BC38XhsVKrurbI, PID: 22922446
-
Schon EA, Area-Gomez E (2013) Mitochondria-associated ER membranes in Alzheimer disease. Mol Cell Neurosci 55:26–36
-
(2013)
Mol Cell Neurosci
, vol.55
, pp. 26-36
-
-
Schon, E.A.1
Area-Gomez, E.2
-
129
-
-
44649150145
-
Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells
-
COI: 1:CAS:528:DC%2BD1cXmvVKksrs%3D, PID: 18514418
-
Shavali S, Brown-Borg HM, Ebadi M, Porter J (2008) Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells. Neurosci Lett 439:125–128
-
(2008)
Neurosci Lett
, vol.439
, pp. 125-128
-
-
Shavali, S.1
Brown-Borg, H.M.2
Ebadi, M.3
Porter, J.4
-
130
-
-
0035955478
-
Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients
-
COI: 1:CAS:528:DC%2BD3MXnsF2gsbY%3D, PID: 11602233
-
Shibata N, Nagai R, Uchida K, Horiuchi S, Yamada S, Hirano A, Kawaguchi M, Yamamoto T, Sasaki S, Kobayashi M (2001) Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. Brain Res 917:97–104
-
(2001)
Brain Res
, vol.917
, pp. 97-104
-
-
Shibata, N.1
Nagai, R.2
Uchida, K.3
Horiuchi, S.4
Yamada, S.5
Hirano, A.6
Kawaguchi, M.7
Yamamoto, T.8
Sasaki, S.9
Kobayashi, M.10
-
131
-
-
84855395163
-
Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease
-
COI: 1:CAS:528:DC%2BC38XmtFCm, PID: 21997870
-
Shirendeb UP, Calkins MJ, Manczak M, Anekonda V, Dufour B, McBride JL, Mao P, Reddy PH (2012) Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease. Hum Mol Genet 21:406–420
-
(2012)
Hum Mol Genet
, vol.21
, pp. 406-420
-
-
Shirendeb, U.P.1
Calkins, M.J.2
Manczak, M.3
Anekonda, V.4
Dufour, B.5
McBride, J.L.6
Mao, P.7
Reddy, P.H.8
-
132
-
-
0025871358
-
Mitochondrial membrane contact sites of yeast. Characterization of lipid components and possible involvement in intramitochondrial translocation of phospholipids
-
COI: 1:CAS:528:DyaK3MXkvVyqt7g%3D, PID: 2037561
-
Simbeni R, Pon L, Zinser E, Paltauf F, Daum G (1991) Mitochondrial membrane contact sites of yeast. Characterization of lipid components and possible involvement in intramitochondrial translocation of phospholipids. J Biol Chem 266:10047–10049
-
(1991)
J Biol Chem
, vol.266
, pp. 10047-10049
-
-
Simbeni, R.1
Pon, L.2
Zinser, E.3
Paltauf, F.4
Daum, G.5
-
133
-
-
77957167810
-
Revitalizing membrane rafts: new tools and insights
-
COI: 1:CAS:528:DC%2BC3cXhtFylur%2FI, PID: 20861879
-
Simons K, Gerl MJ (2010) Revitalizing membrane rafts: new tools and insights. Nat Rev Mol Cell Biol 11:688–699
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 688-699
-
-
Simons, K.1
Gerl, M.J.2
-
134
-
-
0034623715
-
The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis
-
COI: 1:CAS:528:DC%2BD3cXoslymtLk%3D, PID: 11027675
-
Siskind LJ, Colombini M (2000) The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis. J Biol Chem 275:38640–38644
-
(2000)
J Biol Chem
, vol.275
, pp. 38640-38644
-
-
Siskind, L.J.1
Colombini, M.2
-
135
-
-
79952443408
-
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
-
COI: 1:CAS:528:DC%2BC3MXit1aitLw%3D, PID: 21336284
-
Song W, Chen J, Petrilli A, Liot G, Klinglmayr E, Zhou Y, Poquiz P, Tjong J, Pouladi MA, Hayden MR (2011) Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat Med 17:377–382
-
(2011)
Nat Med
, vol.17
, pp. 377-382
-
-
Song, W.1
Chen, J.2
Petrilli, A.3
Liot, G.4
Klinglmayr, E.5
Zhou, Y.6
Poquiz, P.7
Tjong, J.8
Pouladi, M.A.9
Hayden, M.R.10
-
136
-
-
67849133020
-
Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria
-
COI: 1:CAS:528:DC%2BD1MXptlahur8%3D, PID: 19616549
-
Sorice M, Manganelli V, Matarrese P, Tinari A, Misasi R, Malorni W, Garofalo T (2009) Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria. FEBS Lett 583:2447–2450
-
(2009)
FEBS Lett
, vol.583
, pp. 2447-2450
-
-
Sorice, M.1
Manganelli, V.2
Matarrese, P.3
Tinari, A.4
Misasi, R.5
Malorni, W.6
Garofalo, T.7
-
137
-
-
84871537265
-
Reconstitution of mitochondria derived vesicle formation demonstrates selective enrichment of oxidized cargo
-
COI: 1:CAS:528:DC%2BC3sXmvFCqtw%3D%3D, PID: 23300790
-
Soubannier V, Rippstein P, Kaufman BA, Shoubridge EA, McBride HM (2012) Reconstitution of mitochondria derived vesicle formation demonstrates selective enrichment of oxidized cargo. PLoS ONE 7:e52830
-
(2012)
PLoS ONE
, vol.7
-
-
Soubannier, V.1
Rippstein, P.2
Kaufman, B.A.3
Shoubridge, E.A.4
McBride, H.M.5
-
138
-
-
0024294841
-
Lipid topology and physical properties of the outer mitochondrial membrane of the yeast, Saccharomyces cerevisiae
-
COI: 1:CAS:528:DyaL1MXnt1aiuw%3D%3D, PID: 3061466
-
Sperka-Gottlieb CD, Hermetter A, Paltauf F, Daum G (1988) Lipid topology and physical properties of the outer mitochondrial membrane of the yeast, Saccharomyces cerevisiae. Biochim Biophys Acta 946:227–234
-
(1988)
Biochim Biophys Acta
, vol.946
, pp. 227-234
-
-
Sperka-Gottlieb, C.D.1
Hermetter, A.2
Paltauf, F.3
Daum, G.4
-
139
-
-
85034085252
-
Sphingolipids and mitochondrial function, lessons learned from yeast
-
COI: 1:CAS:528:DC%2BC2MXitV2iurbJ
-
Spincemaille P, Cammue BP, Thevissen K (2014) Sphingolipids and mitochondrial function, lessons learned from yeast. Microb Cell 1:210–224
-
(2014)
Microb Cell
, vol.1
, pp. 210-224
-
-
Spincemaille, P.1
Cammue, B.P.2
Thevissen, K.3
-
140
-
-
0034881033
-
Oxidative stress and protein aggregation during biological aging
-
COI: 1:CAS:528:DC%2BD3MXmt1Kktro%3D, PID: 11525876
-
Squier TC (2001) Oxidative stress and protein aggregation during biological aging. Exp Gerontol 36:1539–1550
-
(2001)
Exp Gerontol
, vol.36
, pp. 1539-1550
-
-
Squier, T.C.1
-
141
-
-
84855226995
-
Genotype-, aging-dependent abnormal caspase activity in Huntington disease blood cells
-
COI: 1:CAS:528:DC%2BC3MXhtlGkurzK, PID: 21519949
-
Squitieri F, Maglione V, Orobello S, Fornai F (2011) Genotype-, aging-dependent abnormal caspase activity in Huntington disease blood cells. J Neural Transm 118:1599–1607
-
(2011)
J Neural Transm
, vol.118
, pp. 1599-1607
-
-
Squitieri, F.1
Maglione, V.2
Orobello, S.3
Fornai, F.4
-
142
-
-
0037354119
-
Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3β, and induction of the mitochondrial-dependent intrinsic caspase pathway
-
COI: 1:CAS:528:DC%2BD3sXis1yqt7c%3D, PID: 12691738
-
Stoica BA, Movsesyan VA, Lea Iv PM, Faden AI (2003) Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3β, and induction of the mitochondrial-dependent intrinsic caspase pathway. Mol Cell Neurosci 22:365–382
-
(2003)
Mol Cell Neurosci
, vol.22
, pp. 365-382
-
-
Stoica, B.A.1
Movsesyan, V.A.2
Lea Iv, P.M.3
Faden, A.I.4
-
143
-
-
84901925681
-
ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
-
Stoica R, De Vos KJ, Paillusson S, Mueller S, Sancho RM, Lau K, Vizcay-Barrena G, Lin W, Xu Y, Lewis J (2014) ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43. Nat Commun 5
-
(2014)
Nat Commun
, pp. 5
-
-
Stoica, R.1
De Vos, K.J.2
Paillusson, S.3
Mueller, S.4
Sancho, R.M.5
Lau, K.6
Vizcay-Barrena, G.7
Lin, W.8
Xu, Y.9
Lewis, J.10
-
144
-
-
0034602158
-
Phosphatidylserine synthase-1 and −2 are localized to mitochondria-associated membranes
-
COI: 1:CAS:528:DC%2BD3cXotFWltrY%3D, PID: 10938271
-
Stone SJ, Vance JE (2000) Phosphatidylserine synthase-1 and −2 are localized to mitochondria-associated membranes. J Biol Chem 275:34534–34540
-
(2000)
J Biol Chem
, vol.275
, pp. 34534-34540
-
-
Stone, S.J.1
Vance, J.E.2
-
145
-
-
64149132208
-
The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria
-
COI: 1:CAS:528:DC%2BD1MXhvVSntLk%3D, PID: 19049983
-
Stone SJ, Levin MC, Zhou P, Han J, Walther TC, Farese RV Jr (2009) The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria. J Biol Chem 284:5352–5361
-
(2009)
J Biol Chem
, vol.284
, pp. 5352-5361
-
-
Stone, S.J.1
Levin, M.C.2
Zhou, P.3
Han, J.4
Walther, T.C.5
Farese, R.V.6
-
146
-
-
33845692166
-
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels
-
COI: 1:CAS:528:DC%2BD2sXpsVc%3D, PID: 17178908
-
Szabadkai G, Bianchi K, Varnai P, De Stefani D, Wieckowski MR, Cavagna D, Nagy AI, Balla T, Rizzuto R (2006) Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. J Cell Biol 175:901–911
-
(2006)
J Cell Biol
, vol.175
, pp. 901-911
-
-
Szabadkai, G.1
Bianchi, K.2
Varnai, P.3
De Stefani, D.4
Wieckowski, M.R.5
Cavagna, D.6
Nagy, A.I.7
Balla, T.8
Rizzuto, R.9
-
147
-
-
0033982887
-
Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse
-
COI: 1:STN:280:DC%2BD3c%2FpsF2ltw%3D%3D, PID: 10632104
-
Tabrizi S, Workman J, Hart P, Mangiarini L, Mahal A, Bates G, Cooper J, Schapira A (2000) Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse. Ann Neurol 47:80–86
-
(2000)
Ann Neurol
, vol.47
, pp. 80-86
-
-
Tabrizi, S.1
Workman, J.2
Hart, P.3
Mangiarini, L.4
Mahal, A.5
Bates, G.6
Cooper, J.7
Schapira, A.8
-
148
-
-
84955350049
-
ApoE4 upregulates the activity of mitochondria-associated ER membranes
-
COI: 1:CAS:528:DC%2BC2MXhvVajs77M, PID: 26564908
-
Tambini MD, Pera M, Kanter E, Yang H, Guardia-Laguarta C, Holtzman D, Sulzer D, Area-Gomez E, Schon EA (2016) ApoE4 upregulates the activity of mitochondria-associated ER membranes. EMBO Rep 17:27–36
-
(2016)
EMBO Rep
, vol.17
, pp. 27-36
-
-
Tambini, M.D.1
Pera, M.2
Kanter, E.3
Yang, H.4
Guardia-Laguarta, C.5
Holtzman, D.6
Sulzer, D.7
Area-Gomez, E.8
Schon, E.A.9
-
149
-
-
84906318502
-
Phospholipid transport via mitochondria
-
COI: 1:CAS:528:DC%2BC2cXhtl2ru77E, PID: 24954234
-
Tamura Y, Sesaki H, Endo T (2014) Phospholipid transport via mitochondria. Traffic 15:933–945
-
(2014)
Traffic
, vol.15
, pp. 933-945
-
-
Tamura, Y.1
Sesaki, H.2
Endo, T.3
-
150
-
-
84873671181
-
Phosphatidylethanolamine deficiency in Mammalian mitochondria impairs oxidative phosphorylation and alters mitochondrial morphology
-
COI: 1:CAS:528:DC%2BC3sXit1Kks7Y%3D, PID: 23250747
-
Tasseva G, Bai HD, Davidescu M, Haromy A, Michelakis E, Vance JE (2013) Phosphatidylethanolamine deficiency in Mammalian mitochondria impairs oxidative phosphorylation and alters mitochondrial morphology. J Biol Chem 288:4158–4173
-
(2013)
J Biol Chem
, vol.288
, pp. 4158-4173
-
-
Tasseva, G.1
Bai, H.D.2
Davidescu, M.3
Haromy, A.4
Michelakis, E.5
Vance, J.E.6
-
151
-
-
71549148116
-
Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at Stages I/II of Alzheimer's disease pathology
-
COI: 1:CAS:528:DC%2BC3cXpvFOlsg%3D%3D, PID: 19298596
-
Terni B, Boada J, Portero-Otin M, Pamplona R, Ferrer I (2010) Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at Stages I/II of Alzheimer's disease pathology. Brain Pathol 20:222–233
-
(2010)
Brain Pathol
, vol.20
, pp. 222-233
-
-
Terni, B.1
Boada, J.2
Portero-Otin, M.3
Pamplona, R.4
Ferrer, I.5
-
152
-
-
84920508024
-
Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance
-
PID: 24647101
-
Tsang CK, Liu Y, Thomas J, Zhang Y, Zheng XS (2014) Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance. Nat Commun 5:3446
-
(2014)
Nat Commun
, vol.5
, pp. 3446
-
-
Tsang, C.K.1
Liu, Y.2
Thomas, J.3
Zhang, Y.4
Zheng, X.S.5
-
153
-
-
0032848506
-
Lipid composition of subcellular membranes of an FY1679-derived haploid yeast wild-type strain grown on different carbon sources
-
COI: 1:CAS:528:DyaK1MXmvFOitbs%3D, PID: 10514572
-
Tuller G, Nemec T, Hrastnik C, Daum G (1999) Lipid composition of subcellular membranes of an FY1679-derived haploid yeast wild-type strain grown on different carbon sources. Yeast 15:1555–1564
-
(1999)
Yeast
, vol.15
, pp. 1555-1564
-
-
Tuller, G.1
Nemec, T.2
Hrastnik, C.3
Daum, G.4
-
154
-
-
73949155373
-
Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease
-
COI: 1:CAS:528:DC%2BD1MXhtl2qtbzO, PID: 19642201
-
Valencia A, Reeves PB, Sapp E, Li X, Alexander J, Kegel KB, Chase K, Aronin N, DiFiglia M (2010) Mutant huntingtin and glycogen synthase kinase 3-β accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease. J Neurosci Res 88:179–190
-
(2010)
J Neurosci Res
, vol.88
, pp. 179-190
-
-
Valencia, A.1
Reeves, P.B.2
Sapp, E.3
Li, X.4
Alexander, J.5
Kegel, K.B.6
Chase, K.7
Aronin, N.8
DiFiglia, M.9
-
156
-
-
84904967279
-
New functions of mitochondria associated membranes in cellular signaling
-
PID: 24642268
-
van Vliet AR, Verfaillie T, Agostinis P (2014) New functions of mitochondria associated membranes in cellular signaling. Biochim Biophys Acta 1843:2253–2262
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 2253-2262
-
-
van Vliet, A.R.1
Verfaillie, T.2
Agostinis, P.3
-
157
-
-
84896871426
-
MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond
-
COI: 1:CAS:528:DC%2BC2cXks1Olsr0%3D, PID: 24316057
-
Vance JE (2014) MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond. Biochim Biophys Acta 1841:595–609
-
(2014)
Biochim Biophys Acta
, vol.1841
, pp. 595-609
-
-
Vance, J.E.1
-
158
-
-
0031576839
-
Abnormalities in mitochondria-associated membranes and phospholipid biosynthetic enzymes in the mnd/mnd mouse model of neuronal ceroid lipofuscinosis
-
COI: 1:CAS:528:DyaK2sXmsVWmuw%3D%3D, PID: 9059519
-
Vance JE, Stone SJ, Faust JR (1997) Abnormalities in mitochondria-associated membranes and phospholipid biosynthetic enzymes in the mnd/mnd mouse model of neuronal ceroid lipofuscinosis. Biochim Biophys Acta 1344:286–299
-
(1997)
Biochim Biophys Acta
, vol.1344
, pp. 286-299
-
-
Vance, J.E.1
Stone, S.J.2
Faust, J.R.3
-
159
-
-
33749527232
-
Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion
-
COI: 1:CAS:528:DC%2BD28XhtVyht7%2FI, PID: 17001002
-
Vicogne J, Vollenweider D, Smith JR, Huang P, Frohman MA, Pessin JE (2006) Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion. Proc Natl Acad Sci U S A 103:14761–14766
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14761-14766
-
-
Vicogne, J.1
Vollenweider, D.2
Smith, J.R.3
Huang, P.4
Frohman, M.A.5
Pessin, J.E.6
-
160
-
-
0035873494
-
Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells
-
COI: 1:CAS:528:DC%2BD3MXktFegurc%3D, PID: 11350931
-
Vitale N, Caumont AS, Chasserot-Golaz S, Du G, Wu S, Sciorra VA, Morris AJ, Frohman MA, Bader MF (2001) Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells. EMBO J 20:2424–2434
-
(2001)
EMBO J
, vol.20
, pp. 2424-2434
-
-
Vitale, N.1
Caumont, A.S.2
Chasserot-Golaz, S.3
Du, G.4
Wu, S.5
Sciorra, V.A.6
Morris, A.J.7
Frohman, M.A.8
Bader, M.F.9
-
161
-
-
84975804407
-
The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1
-
PID: 26347140
-
Vogtle FN, Keller M, Taskin AA, Horvath SE, Guan XL, Prinz C, Opalinska M, Zorzin C, van der Laan M, Wenk MR, Schubert R, Wiedemann N, Holzer M, Meisinger C (2015) The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1. J Cell Biol 210:951–960
-
(2015)
J Cell Biol
, vol.210
, pp. 951-960
-
-
Vogtle, F.N.1
Keller, M.2
Taskin, A.A.3
Horvath, S.E.4
Guan, X.L.5
Prinz, C.6
Opalinska, M.7
Zorzin, C.8
van der Laan, M.9
Wenk, M.R.10
Schubert, R.11
Wiedemann, N.12
Holzer, M.13
Meisinger, C.14
-
162
-
-
0037046163
-
Vesicle permeabilization by protofibrillar α-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism
-
COI: 1:CAS:528:DC%2BD38XhvVeqt70%3D, PID: 11926821
-
Volles MJ, Lansbury PT (2002) Vesicle permeabilization by protofibrillar α-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism. Biochemistry 41:4595–4602
-
(2002)
Biochemistry
, vol.41
, pp. 4595-4602
-
-
Volles, M.J.1
Lansbury, P.T.2
-
163
-
-
0035800097
-
Vesicle permeabilization by protofibrillar α-synuclein: implications for the pathogenesis and treatment of Parkinson's disease
-
COI: 1:CAS:528:DC%2BD3MXktFOntb0%3D, PID: 11425308
-
Volles MJ, Lee S, Rochet J, Shtilerman MD, Ding TT, Kessler JC, Lansbury PT (2001) Vesicle permeabilization by protofibrillar α-synuclein: implications for the pathogenesis and treatment of Parkinson's disease. Biochemistry 40:7812–7819
-
(2001)
Biochemistry
, vol.40
, pp. 7812-7819
-
-
Volles, M.J.1
Lee, S.2
Rochet, J.3
Shtilerman, M.D.4
Ding, T.T.5
Kessler, J.C.6
Lansbury, P.T.7
-
164
-
-
84872202122
-
ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae
-
COI: 1:CAS:528:DC%2BC3sXhs1OhtLo%3D, PID: 22797914
-
Voss C, Lahiri S, Young BP, Loewen CJ, Prinz WA (2012) ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae. J Cell Sci 125:4791–4799
-
(2012)
J Cell Sci
, vol.125
, pp. 4791-4799
-
-
Voss, C.1
Lahiri, S.2
Young, B.P.3
Loewen, C.J.4
Prinz, W.A.5
-
165
-
-
84887416057
-
Mitophagy and neurodegeneration: the zebrafish model system
-
COI: 1:CAS:528:DC%2BC2cXhtVyiurzJ, PID: 23939015
-
Wager K, Russell C (2013) Mitophagy and neurodegeneration: the zebrafish model system. Autophagy 9:1693–1709
-
(2013)
Autophagy
, vol.9
, pp. 1693-1709
-
-
Wager, K.1
Russell, C.2
-
166
-
-
0036180950
-
Cholesterol-dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains
-
COI: 1:CAS:528:DC%2BD38Xht1GnsLc%3D, PID: 11848681
-
Wahrle S, Das P, Nyborg AC, McLendon C, Shoji M, Kawarabayashi T, Younkin LH, Younkin SG, Golde TE (2002) Cholesterol-dependent γ-secretase activity in buoyant cholesterol-rich membrane microdomains. Neurobiol Dis 9:11–23
-
(2002)
Neurobiol Dis
, vol.9
, pp. 11-23
-
-
Wahrle, S.1
Das, P.2
Nyborg, A.C.3
McLendon, C.4
Shoji, M.5
Kawarabayashi, T.6
Younkin, L.H.7
Younkin, S.G.8
Golde, T.E.9
-
167
-
-
79952319773
-
Mitochondria removal by autophagy
-
COI: 1:CAS:528:DC%2BC3MXjvFOhsro%3D, PID: 21252623
-
Wang K, Klionsky DJ (2011) Mitochondria removal by autophagy. Autophagy 7:297–300
-
(2011)
Autophagy
, vol.7
, pp. 297-300
-
-
Wang, K.1
Klionsky, D.J.2
-
168
-
-
84907190544
-
Phosphatidylethanolamine deficiency disrupts alpha-synuclein homeostasis in yeast and worm models of Parkinson disease
-
COI: 1:CAS:528:DC%2BC2cXhsFSju7jP, PID: 25201965
-
Wang S, Zhang S, Liou LC, Ren Q, Zhang Z, Caldwell GA, Caldwell KA, Witt SN (2014) Phosphatidylethanolamine deficiency disrupts alpha-synuclein homeostasis in yeast and worm models of Parkinson disease. Proc Natl Acad Sci U S A 111:E3976–E3985
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E3976-E3985
-
-
Wang, S.1
Zhang, S.2
Liou, L.C.3
Ren, Q.4
Zhang, Z.5
Caldwell, G.A.6
Caldwell, K.A.7
Witt, S.N.8
-
169
-
-
0029917194
-
Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease
-
COI: 1:CAS:528:DyaK28XitVCis7Y%3D, PID: 8610103
-
Yoritaka A, Hattori N, Uchida K, Tanaka M, Stadtman ER, Mizuno Y (1996) Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. Proc Natl Acad Sci U S A 93:2696–2701
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 2696-2701
-
-
Yoritaka, A.1
Hattori, N.2
Uchida, K.3
Tanaka, M.4
Stadtman, E.R.5
Mizuno, Y.6
-
170
-
-
55549115322
-
Formation of phosphatidic acid in stressed mitochondria
-
COI: 1:CAS:528:DC%2BD1cXhtlGhu7%2FE, PID: 18835242
-
Yurkova IL, Stuckert F, Kisel MA, Shadyro OI, Arnhold J, Huster D (2008) Formation of phosphatidic acid in stressed mitochondria. Arch Biochem Biophys 480:17–26
-
(2008)
Arch Biochem Biophys
, vol.480
, pp. 17-26
-
-
Yurkova, I.L.1
Stuckert, F.2
Kisel, M.A.3
Shadyro, O.I.4
Arnhold, J.5
Huster, D.6
-
171
-
-
79952600977
-
Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk
-
COI: 1:CAS:528:DC%2BC3MXisVeksbg%3D, PID: 21285369
-
Zampese E, Fasolato C, Kipanyula MJ, Bortolozzi M, Pozzan T, Pizzo P (2011) Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk. Proc Natl Acad Sci U S A 108:2777–2782
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 2777-2782
-
-
Zampese, E.1
Fasolato, C.2
Kipanyula, M.J.3
Bortolozzi, M.4
Pozzan, T.5
Pizzo, P.6
-
172
-
-
66249085542
-
Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord
-
COI: 1:CAS:528:DC%2BD1MXos1ars74%3D, PID: 19438725
-
Zhai J, Ström A, Kilty R, Venkatakrishnan P, White J, Everson WV, Smart EJ, Zhu H (2009) Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord. FEBS J 276:3308–3323
-
(2009)
FEBS J
, vol.276
, pp. 3308-3323
-
-
Zhai, J.1
Ström, A.2
Kilty, R.3
Venkatakrishnan, P.4
White, J.5
Everson, W.V.6
Smart, E.J.7
Zhu, H.8
-
173
-
-
84862777869
-
Interaction of α-synuclein with vesicles that mimic mitochondrial membranes
-
COI: 1:CAS:528:DC%2BC38XhvFeisL0%3D, PID: 22155643
-
Zigoneanu IG, Yang YJ, Krois AS, Haque ME, Pielak GJ (2012) Interaction of α-synuclein with vesicles that mimic mitochondrial membranes. Biochim Biophys Acta 1818:512–519
-
(2012)
Biochim Biophys Acta
, vol.1818
, pp. 512-519
-
-
Zigoneanu, I.G.1
Yang, Y.J.2
Krois, A.S.3
Haque, M.E.4
Pielak, G.J.5
-
174
-
-
0026082909
-
Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae
-
COI: 1:CAS:528:DyaK3MXitVehsb4%3D, PID: 2002005
-
Zinser E, Sperka-Gottlieb CD, Fasch EV, Kohlwein SD, Paltauf F, Daum G (1991) Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J Bacteriol 173:2026–2034
-
(1991)
J Bacteriol
, vol.173
, pp. 2026-2034
-
-
Zinser, E.1
Sperka-Gottlieb, C.D.2
Fasch, E.V.3
Kohlwein, S.D.4
Paltauf, F.5
Daum, G.6
-
175
-
-
2442589922
-
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
-
PID: 15064763
-
Züchner S, Mersiyanova IV, Muglia M, Bissar-Tadmouri N, Rochelle J, Dadali EL, Zappia M, Nelis E, Patitucci A, Senderek J (2004) Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat Genet 36:449–451
-
(2004)
Nat Genet
, vol.36
, pp. 449-451
-
-
Züchner, S.1
Mersiyanova, I.V.2
Muglia, M.3
Bissar-Tadmouri, N.4
Rochelle, J.5
Dadali, E.L.6
Zappia, M.7
Nelis, E.8
Patitucci, A.9
Senderek, J.10
|