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Volumn 55, Issue , 2013, Pages 77-86

D. melanogaster, mitochondria and neurodegeneration: Small model organism, big discoveries

Author keywords

Charcot Marie Tooth IIa; Dominant optic atrophy; Drosophila melanogaster; Fusion fission; Mitochondria; Neurodegenerative diseases

Indexed keywords

MITOCHONDRIAL PROTEIN; MITOFUSIN 2; PARKIN;

EID: 84875602384     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2012.08.007     Document Type: Article
Times cited : (17)

References (120)
  • 3
    • 35948971242 scopus 로고    scopus 로고
    • Roles for Drp1, a dynamin-related protein, and milton, a kinesin-associated protein, in mitochondrial segregation, unfurling and elongation during Drosophila spermatogenesis
    • Aldridge A.C., Benson L.P., Siegenthaler M.M., Whigham B.T., Stowers R.S., Hales K.G. Roles for Drp1, a dynamin-related protein, and milton, a kinesin-associated protein, in mitochondrial segregation, unfurling and elongation during Drosophila spermatogenesis. Fly (Austin) 2007, 1:38-46.
    • (2007) Fly (Austin) , vol.1 , pp. 38-46
    • Aldridge, A.C.1    Benson, L.P.2    Siegenthaler, M.M.3    Whigham, B.T.4    Stowers, R.S.5    Hales, K.G.6
  • 4
    • 33750526651 scopus 로고    scopus 로고
    • The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis
    • Alirol E., James D., Huber D., Marchetto A., Vergani L., Martinou J.C., Scorrano L. The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis. Mol. Biol. Cell 2006, 17:4593-4605.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4593-4605
    • Alirol, E.1    James, D.2    Huber, D.3    Marchetto, A.4    Vergani, L.5    Martinou, J.C.6    Scorrano, L.7
  • 6
    • 33846224191 scopus 로고    scopus 로고
    • Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations
    • Baloh R.H., Schmidt R.E., Pestronk A., Milbrandt J. Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations. J. Neurosci. 2007, 27:422-430.
    • (2007) J. Neurosci. , vol.27 , pp. 422-430
    • Baloh, R.H.1    Schmidt, R.E.2    Pestronk, A.3    Milbrandt, J.4
  • 7
    • 0033580705 scopus 로고    scopus 로고
    • Mutant fruit flies respond to Lorenzo's oil
    • Barinaga M. Mutant fruit flies respond to Lorenzo's oil. Science 1999, 284(1899):1901.
    • (1999) Science , vol.284 , Issue.1899 , pp. 1901
    • Barinaga, M.1
  • 8
    • 0028047262 scopus 로고
    • Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria
    • Bereiter-Hahn J., Voth M. Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondria. Microsc. Res. Tech. 1994, 27:198-219.
    • (1994) Microsc. Res. Tech. , vol.27 , pp. 198-219
    • Bereiter-Hahn, J.1    Voth, M.2
  • 10
    • 0037302522 scopus 로고    scopus 로고
    • Patterning the fly eye: the role of apoptosis
    • Brachmann C.B., Cagan R.L. Patterning the fly eye: the role of apoptosis. Trends Genet. 2003, 19:91-96.
    • (2003) Trends Genet. , vol.19 , pp. 91-96
    • Brachmann, C.B.1    Cagan, R.L.2
  • 11
    • 51449085299 scopus 로고    scopus 로고
    • The role of autophagy in mammalian development: cell makeover rather than cell death
    • Cecconi F., Levine B. The role of autophagy in mammalian development: cell makeover rather than cell death. Dev. Cell 2008, 15:344-357.
    • (2008) Dev. Cell , vol.15 , pp. 344-357
    • Cecconi, F.1    Levine, B.2
  • 16
    • 34547601410 scopus 로고    scopus 로고
    • Mitochondrial fusion protects against neurodegeneration in the cerebellum
    • Chen H., McCaffery J.M., Chan D.C. Mitochondrial fusion protects against neurodegeneration in the cerebellum. Cell 2007, 130:548-562.
    • (2007) Cell , vol.130 , pp. 548-562
    • Chen, H.1    McCaffery, J.M.2    Chan, D.C.3
  • 17
    • 64249133725 scopus 로고    scopus 로고
    • S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
    • Cho D.H., Nakamura T., Fang J., Cieplak P., Godzik A., Gu Z., Lipton S.A. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science 2009, 324:102-105.
    • (2009) Science , vol.324 , pp. 102-105
    • Cho, D.H.1    Nakamura, T.2    Fang, J.3    Cieplak, P.4    Godzik, A.5    Gu, Z.6    Lipton, S.A.7
  • 20
    • 33745589773 scopus 로고    scopus 로고
    • Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
    • Clark I.E., Dodson M.W., Jiang C., Cao J.H., Huh J.R., Seol J.H., Yoo S.J., Hay B.A., Guo M. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 2006, 441:1162-1166.
    • (2006) Nature , vol.441 , pp. 1162-1166
    • Clark, I.E.1    Dodson, M.W.2    Jiang, C.3    Cao, J.H.4    Huh, J.R.5    Seol, J.H.6    Yoo, S.J.7    Hay, B.A.8    Guo, M.9
  • 21
    • 0036645679 scopus 로고    scopus 로고
    • GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway
    • Claveria C., Caminero E., Martinez A.C., Campuzano S., Torres M. GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathway. EMBO J. 2002, 21:3327-3336.
    • (2002) EMBO J. , vol.21 , pp. 3327-3336
    • Claveria, C.1    Caminero, E.2    Martinez, A.C.3    Campuzano, S.4    Torres, M.5
  • 22
    • 84859904873 scopus 로고    scopus 로고
    • Shaping the role of mitochondria in the pathogenesis of Huntington's disease
    • Costa V., Scorrano L. Shaping the role of mitochondria in the pathogenesis of Huntington's disease. EMBO J. 2012, 31:1853-1864.
    • (2012) EMBO J. , vol.31 , pp. 1853-1864
    • Costa, V.1    Scorrano, L.2
  • 24
    • 67649399288 scopus 로고    scopus 로고
    • Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
    • (May 15)
    • Dagda R.K., Cherra S.J., Kulich S.M., Tandon A., Park D., Chu C.T. Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J. Biol. Chem. 2009, 284(20):13843-13855. (May 15).
    • (2009) J. Biol. Chem. , vol.284 , Issue.20 , pp. 13843-13855
    • Dagda, R.K.1    Cherra, S.J.2    Kulich, S.M.3    Tandon, A.4    Park, D.5    Chu, C.T.6
  • 25
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 26
    • 34447314190 scopus 로고    scopus 로고
    • Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function
    • Davies V.J., Hollins A.J., Piechota M.J., Yip W., Davies J.R., White K.E., Nicols P.P., Boulton M.E., Votruba M. Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function. Hum. Mol. Genet. 2007, 16:1307-1318.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 1307-1318
    • Davies, V.J.1    Hollins, A.J.2    Piechota, M.J.3    Yip, W.4    Davies, J.R.5    White, K.E.6    Nicols, P.P.7    Boulton, M.E.8    Votruba, M.9
  • 27
    • 57349100367 scopus 로고    scopus 로고
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria
    • de Brito O.M., Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008, 456:605-610.
    • (2008) Nature , vol.456 , pp. 605-610
    • de Brito, O.M.1    Scorrano, L.2
  • 29
    • 55749090654 scopus 로고    scopus 로고
    • The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
    • Deng H., Dodson M.W., Huang H., Guo M. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:14503-14508.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 14503-14508
    • Deng, H.1    Dodson, M.W.2    Huang, H.3    Guo, M.4
  • 31
    • 0037128924 scopus 로고    scopus 로고
    • The role of cytochrome c in caspase activation in Drosophila melanogaster cells
    • Dorstyn L., Read S., Cakouros D., Huh J.R., Hay B.A., Kumar S. The role of cytochrome c in caspase activation in Drosophila melanogaster cells. J. Cell Biol. 2002, 156(6):1089-1098.
    • (2002) J. Cell Biol. , vol.156 , Issue.6 , pp. 1089-1098
    • Dorstyn, L.1    Read, S.2    Cakouros, D.3    Huh, J.R.4    Hay, B.A.5    Kumar, S.6
  • 32
    • 8444227809 scopus 로고    scopus 로고
    • The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells
    • Dorstyn L., Mills K., Lazebnik Y., Kumar S. The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells. J. Cell Biol. 2004, 167:405-410.
    • (2004) J. Cell Biol. , vol.167 , pp. 405-410
    • Dorstyn, L.1    Mills, K.2    Lazebnik, Y.3    Kumar, S.4
  • 36
    • 79955106109 scopus 로고    scopus 로고
    • Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila
    • Fernandes C., Rao Y. Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila. Mol. Brain 2011, 4:17.
    • (2011) Mol. Brain , vol.4 , pp. 17
    • Fernandes, C.1    Rao, Y.2
  • 39
    • 24944525045 scopus 로고    scopus 로고
    • Molecular pathogenesis of Parkinson's disease
    • Gandhi S., Wood N.W. Molecular pathogenesis of Parkinson's disease. Hum. Mol. Genet. 2005, 14:2749-2755.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 2749-2755
    • Gandhi, S.1    Wood, N.W.2
  • 40
    • 44649129342 scopus 로고    scopus 로고
    • The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells
    • Gandre-Babbe S., van der Bliek A.M. The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells. Mol. Biol. Cell 2008, 19:2402-2412.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2402-2412
    • Gandre-Babbe, S.1    van der Bliek, A.M.2
  • 41
    • 33646768127 scopus 로고    scopus 로고
    • Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent
    • Glater E.E., Megeath L.J., Stowers R.S., Schwarz T.L. Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J. Cell Biol. 2006, 173:545-557.
    • (2006) J. Cell Biol. , vol.173 , pp. 545-557
    • Glater, E.E.1    Megeath, L.J.2    Stowers, R.S.3    Schwarz, T.L.4
  • 42
    • 79955623510 scopus 로고    scopus 로고
    • During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
    • Gomes L.C., Di B.G., Scorrano L. During autophagy mitochondria elongate, are spared from degradation and sustain cell viability. Nat. Cell Biol. 2011, 13:589-598.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 589-598
    • Gomes, L.C.1    Di, B.G.2    Scorrano, L.3
  • 45
    • 34548313686 scopus 로고    scopus 로고
    • Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
    • Griparic L., Kanazawa T., van der Bliek A.M. Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage. J. Cell Biol. 2007, 178:757-764.
    • (2007) J. Cell Biol. , vol.178 , pp. 757-764
    • Griparic, L.1    Kanazawa, T.2    van der Bliek, A.M.3
  • 46
    • 77957222311 scopus 로고    scopus 로고
    • What have we learned from Drosophila models of Parkinson's disease?
    • Guo M. What have we learned from Drosophila models of Parkinson's disease?. Prog. Brain Res. 2010, 184:3-16.
    • (2010) Prog. Brain Res. , vol.184 , pp. 3-16
    • Guo, M.1
  • 49
    • 0031440879 scopus 로고    scopus 로고
    • Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase
    • Hales K.G., Fuller M.T. Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase. Cell 1997, 90:121-129.
    • (1997) Cell , vol.90 , pp. 121-129
    • Hales, K.G.1    Fuller, M.T.2
  • 51
    • 0018942439 scopus 로고
    • The clinical features of hereditary motor and sensory neuropathy types I and II
    • Harding A.E., Thomas P.K. The clinical features of hereditary motor and sensory neuropathy types I and II. Brain 1980, 103:259-280.
    • (1980) Brain , vol.103 , pp. 259-280
    • Harding, A.E.1    Thomas, P.K.2
  • 52
    • 76149093590 scopus 로고    scopus 로고
    • Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
    • Head B., Griparic L., Amiri M., Gandre-Babbe S., van der Bliek A.M. Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells. J. Cell Biol. 2009, 187:959-966.
    • (2009) J. Cell Biol. , vol.187 , pp. 959-966
    • Head, B.1    Griparic, L.2    Amiri, M.3    Gandre-Babbe, S.4    van der Bliek, A.M.5
  • 53
    • 77955280924 scopus 로고    scopus 로고
    • The PARL family of mitochondrial rhomboid proteases
    • Hill R.B., Pellegrini L. The PARL family of mitochondrial rhomboid proteases. Semin. Cell Dev. Biol. 2010, 21(6):582-592.
    • (2010) Semin. Cell Dev. Biol. , vol.21 , Issue.6 , pp. 582-592
    • Hill, R.B.1    Pellegrini, L.2
  • 54
    • 0035996992 scopus 로고    scopus 로고
    • Differential expression of the Drosophila mitofusin genes fuzzy onions (fzo) and dmfn
    • Hwa J.J., Hiller M.A., Fuller M.T., Santel A. Differential expression of the Drosophila mitofusin genes fuzzy onions (fzo) and dmfn. Mech. Dev. 2002, 116.
    • (2002) Mech. Dev. , vol.116
    • Hwa, J.J.1    Hiller, M.A.2    Fuller, M.T.3    Santel, A.4
  • 55
    • 2342473791 scopus 로고    scopus 로고
    • Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease
    • Iijima K., Liu H.P., Chiang A.S., Hearn S.A., Konsolaki M., Zhong Y. Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:6623-6628.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 6623-6628
    • Iijima, K.1    Liu, H.P.2    Chiang, A.S.3    Hearn, S.A.4    Konsolaki, M.5    Zhong, Y.6
  • 57
    • 77949505741 scopus 로고    scopus 로고
    • Mitochondrial mislocalization underlies Abeta42-induced neuronal dysfunction in a Drosophila model of Alzheimer's disease
    • Iijima-Ando K., Hearn S.A., Shenton C., Gatt A., Zhao L., Iijima K. Mitochondrial mislocalization underlies Abeta42-induced neuronal dysfunction in a Drosophila model of Alzheimer's disease. PLoS One 2009, 4:e8310.
    • (2009) PLoS One , vol.4
    • Iijima-Ando, K.1    Hearn, S.A.2    Shenton, C.3    Gatt, A.4    Zhao, L.5    Iijima, K.6
  • 58
    • 33746299692 scopus 로고    scopus 로고
    • Regulation of mitochondrial morphology through proteolytic cleavage of OPA1
    • Ishihara N., Fujita Y., Oka T., Mihara K. Regulation of mitochondrial morphology through proteolytic cleavage of OPA1. EMBO J. 2006, 25:2966-2977.
    • (2006) EMBO J. , vol.25 , pp. 2966-2977
    • Ishihara, N.1    Fujita, Y.2    Oka, T.3    Mihara, K.4
  • 61
    • 0029924084 scopus 로고    scopus 로고
    • Dominant optic atrophy mapped to chromosome 3q region. II. Clinical and epidemiological aspects
    • Kjer B., Eiberg H., Kjer P., Rosenberg T. Dominant optic atrophy mapped to chromosome 3q region. II. Clinical and epidemiological aspects. Acta Ophthalmol. Scand. 1996, 74:3-7.
    • (1996) Acta Ophthalmol. Scand. , vol.74 , pp. 3-7
    • Kjer, B.1    Eiberg, H.2    Kjer, P.3    Rosenberg, T.4
  • 63
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer G., Galluzzi L., Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 2007, 87:99-163.
    • (2007) Physiol. Rev. , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 64
    • 0033231549 scopus 로고    scopus 로고
    • C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane
    • Labrousse A.M., Zappaterra M.D., Rube D.A., van der Bliek A.M. C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane. Mol Cell 1999, 4:815-826.
    • (1999) Mol Cell , vol.4 , pp. 815-826
    • Labrousse, A.M.1    Zappaterra, M.D.2    Rube, D.A.3    van der Bliek, A.M.4
  • 65
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997, 91(4):479-489.
    • (1997) Cell , vol.91 , Issue.4 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 66
    • 67650868959 scopus 로고    scopus 로고
    • Mitochondrial dynamics in mammalian health and disease
    • Liesa M., Palacin M., Zorzano A. Mitochondrial dynamics in mammalian health and disease. Physiol. Rev. 2009, 89:799-845.
    • (2009) Physiol. Rev. , vol.89 , pp. 799-845
    • Liesa, M.1    Palacin, M.2    Zorzano, A.3
  • 70
    • 34250624810 scopus 로고    scopus 로고
    • A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases
    • Mandemakers W., Morais V.A., De Strooper B. A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases. J. Cell Sci. 2007, 120:1707-1716.
    • (2007) J. Cell Sci. , vol.120 , pp. 1707-1716
    • Mandemakers, W.1    Morais, V.A.2    De Strooper, B.3
  • 71
    • 0032508669 scopus 로고    scopus 로고
    • Apoptosis induced by Drosophila reaper and grim in a human system. Attenuation by inhibitor of apoptosis proteins (cIAPs)
    • (Sep 11)
    • McCarthy J.V., Dixit V.M. Apoptosis induced by Drosophila reaper and grim in a human system. Attenuation by inhibitor of apoptosis proteins (cIAPs). J. Biol. Chem. 1998, 273(37):24009-24015. (Sep 11).
    • (1998) J. Biol. Chem. , vol.273 , Issue.37 , pp. 24009-24015
    • McCarthy, J.V.1    Dixit, V.M.2
  • 72
    • 33646543714 scopus 로고    scopus 로고
    • Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function
    • McQuibban G.A., Lee J.R., Zheng L., Juusola M., Freeman M. Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function. Curr. Biol. 2006, 16:537-541.
    • (2006) Curr. Biol. , vol.16 , pp. 537-541
    • McQuibban, G.A.1    Lee, J.R.2    Zheng, L.3    Juusola, M.4    Freeman, M.5
  • 74
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra D., Tanaka A., Suen D.F., Youle R.J. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 2008, 183:795-803.
    • (2008) J. Cell Biol. , vol.183 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 75
    • 79957486224 scopus 로고    scopus 로고
    • Sustained elongation of sperm tail promoted by local remodeling of giant mitochondria in Drosophila
    • Noguchi T., Koizumi M., Hayashi S. Sustained elongation of sperm tail promoted by local remodeling of giant mitochondria in Drosophila. Curr. Biol. 2011, 21:805-814.
    • (2011) Curr. Biol. , vol.21 , pp. 805-814
    • Noguchi, T.1    Koizumi, M.2    Hayashi, S.3
  • 76
    • 84857034651 scopus 로고    scopus 로고
    • Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration
    • Oettinghaus B., Licci M., Scorrano L., Frank S. Less than perfect divorces: dysregulated mitochondrial fission and neurodegeneration. Acta Neuropathol. 2012, 123:189-203.
    • (2012) Acta Neuropathol. , vol.123 , pp. 189-203
    • Oettinghaus, B.1    Licci, M.2    Scorrano, L.3    Frank, S.4
  • 78
    • 0037424239 scopus 로고    scopus 로고
    • Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
    • Olichon A., Baricault L., Gas N., Guillou E., Valette A., Belenguer P., Lenaers G. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J. Biol. Chem. 2003, 278:7743-7746.
    • (2003) J. Biol. Chem. , vol.278 , pp. 7743-7746
    • Olichon, A.1    Baricault, L.2    Gas, N.3    Guillou, E.4    Valette, A.5    Belenguer, P.6    Lenaers, G.7
  • 79
    • 33947434544 scopus 로고    scopus 로고
    • OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis
    • Olichon A., Elachouri G., Baricault L., Delettre C., Belenguer P., Lenaers G. OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis. Cell Death Differ. 2007, 14:682-692.
    • (2007) Cell Death Differ. , vol.14 , pp. 682-692
    • Olichon, A.1    Elachouri, G.2    Baricault, L.3    Delettre, C.4    Belenguer, P.5    Lenaers, G.6
  • 82
    • 57749194390 scopus 로고    scopus 로고
    • The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process
    • Park J., Lee G., Chung J. The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process. Biochem. Biophys. Res. Commun. 2009, 378:518-523.
    • (2009) Biochem. Biophys. Res. Commun. , vol.378 , pp. 518-523
    • Park, J.1    Lee, G.2    Chung, J.3
  • 84
    • 20444461625 scopus 로고    scopus 로고
    • The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
    • Pich S., Bach D., Briones P., Liesa M., Camps M., Testar X., Palacin M., Zorzano A. The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system. Hum. Mol. Genet. 2005, 14:1405-1415.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 1405-1415
    • Pich, S.1    Bach, D.2    Briones, P.3    Liesa, M.4    Camps, M.5    Testar, X.6    Palacin, M.7    Zorzano, A.8
  • 85
    • 0032734577 scopus 로고    scopus 로고
    • The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells
    • Pitts K.R., Yoon Y., Krueger E.W., McNiven M.A. The dynamin-like protein DLP1 is essential for normal distribution and morphology of the endoplasmic reticulum and mitochondria in mammalian cells. Mol. Biol. Cell 1999, 10:4403-4417.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 4403-4417
    • Pitts, K.R.1    Yoon, Y.2    Krueger, E.W.3    McNiven, M.A.4
  • 87
    • 77955844260 scopus 로고    scopus 로고
    • The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
    • Poole A.C., Thomas R.E., Yu S., Vincow E.S., Pallanck L. The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS One 2010, 5:e10054.
    • (2010) PLoS One , vol.5
    • Poole, A.C.1    Thomas, R.E.2    Yu, S.3    Vincow, E.S.4    Pallanck, L.5
  • 88
    • 80054841370 scopus 로고    scopus 로고
    • Rhomboid-7 over-expression results in Opa1-like processing and malfunctioning mitochondria
    • Rahman M., Kylsten P. Rhomboid-7 over-expression results in Opa1-like processing and malfunctioning mitochondria. Biochem. Biophys. Res. Commun. 2011, 414:315-320.
    • (2011) Biochem. Biophys. Res. Commun. , vol.414 , pp. 315-320
    • Rahman, M.1    Kylsten, P.2
  • 89
    • 7744232493 scopus 로고    scopus 로고
    • Misfolded proteins, endoplasmic reticulum stress and neurodegeneration
    • Rao R.V., Bredesen D.E. Misfolded proteins, endoplasmic reticulum stress and neurodegeneration. Curr. Opin. Cell Biol. 2004, 16:653-662.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 653-662
    • Rao, R.V.1    Bredesen, D.E.2
  • 90
    • 0017110220 scopus 로고
    • Development of the Drosophila retina, a neurocrystalline lattice
    • Ready D.F., Hanson T.E., Benzer S. Development of the Drosophila retina, a neurocrystalline lattice. Dev. Biol. 1976, 53:217-240.
    • (1976) Dev. Biol. , vol.53 , pp. 217-240
    • Ready, D.F.1    Hanson, T.E.2    Benzer, S.3
  • 91
    • 0034837386 scopus 로고    scopus 로고
    • A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster
    • Reiter L.T., Potocki L., Chien S., Gribskov M., Bier E. A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res. 2001, 11:1114-1125.
    • (2001) Genome Res. , vol.11 , pp. 1114-1125
    • Reiter, L.T.1    Potocki, L.2    Chien, S.3    Gribskov, M.4    Bier, E.5
  • 92
    • 33646768564 scopus 로고    scopus 로고
    • Paradigm lost: milton connects kinesin heavy chain to miro on mitochondria
    • Rice S.E., Gelfand V.I. Paradigm lost: milton connects kinesin heavy chain to miro on mitochondria. J. Cell Biol. 2006, 173:459-461.
    • (2006) J. Cell Biol. , vol.173 , pp. 459-461
    • Rice, S.E.1    Gelfand, V.I.2
  • 95
    • 0037427529 scopus 로고    scopus 로고
    • Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria
    • Satoh M., Hamamoto T., Seo N., Kagawa Y., Endo H. Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria. Biochem. Biophys. Res. Commun. 2003, 300:482-493.
    • (2003) Biochem. Biophys. Res. Commun. , vol.300 , pp. 482-493
    • Satoh, M.1    Hamamoto, T.2    Seo, N.3    Kagawa, Y.4    Endo, H.5
  • 96
    • 0037427412 scopus 로고    scopus 로고
    • Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
    • Scorrano L., Korsmeyer S.J. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem. Biophys. Res. Commun. 2003, 304(3):437-444.
    • (2003) Biochem. Biophys. Res. Commun. , vol.304 , Issue.3 , pp. 437-444
    • Scorrano, L.1    Korsmeyer, S.J.2
  • 97
    • 69949165392 scopus 로고    scopus 로고
    • Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner
    • Shahrestani P., Leung H.T., Le P.K., Pak W.L., Tse S., Ocorr K., Huang T. Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner. PLoS One 2009, 4:e6867.
    • (2009) PLoS One , vol.4
    • Shahrestani, P.1    Leung, H.T.2    Le, P.K.3    Pak, W.L.4    Tse, S.5    Ocorr, K.6    Huang, T.7
  • 98
    • 0035166814 scopus 로고    scopus 로고
    • Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
    • Smirnova E., Griparic L., Shurland D.L., van der Bliek A.M. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol. Biol. Cell 2001, 12:2245-2256.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 2245-2256
    • Smirnova, E.1    Griparic, L.2    Shurland, D.L.3    van der Bliek, A.M.4
  • 99
    • 34548313688 scopus 로고    scopus 로고
    • OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L
    • Song Z., Chen H., Fiket M., Alexander C., Chan D.C. OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L. J. Cell Biol. 2007, 178:749-755.
    • (2007) J. Cell Biol. , vol.178 , pp. 749-755
    • Song, Z.1    Chen, H.2    Fiket, M.3    Alexander, C.4    Chan, D.C.5
  • 100
    • 77958130220 scopus 로고    scopus 로고
    • The interplay between BCL-2 family proteins and mitochondrial morphology in the regulation of apoptosis
    • Soriano M.E., Scorrano L. The interplay between BCL-2 family proteins and mitochondrial morphology in the regulation of apoptosis. Adv. Exp. Med. Biol. 2010, 687:97-114.
    • (2010) Adv. Exp. Med. Biol. , vol.687 , pp. 97-114
    • Soriano, M.E.1    Scorrano, L.2
  • 101
    • 1842479419 scopus 로고    scopus 로고
    • Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology
    • Stojanovski D., Koutsopoulos O.S., Okamoto K., Ryan M.T. Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology. J. Cell Sci. 2004, 117:1201-1210.
    • (2004) J. Cell Sci. , vol.117 , pp. 1201-1210
    • Stojanovski, D.1    Koutsopoulos, O.S.2    Okamoto, K.3    Ryan, M.T.4
  • 102
    • 0037137704 scopus 로고    scopus 로고
    • Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein
    • Stowers R.S., Megeath L.J., Gorska-Andrzejak J., Meinertzhagen I.A., Schwarz T.L. Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron 2002, 36:1063-1077.
    • (2002) Neuron , vol.36 , pp. 1063-1077
    • Stowers, R.S.1    Megeath, L.J.2    Gorska-Andrzejak, J.3    Meinertzhagen, I.A.4    Schwarz, T.L.5
  • 104
    • 84887212354 scopus 로고    scopus 로고
    • Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production
    • Tang S., Le P.K., Tse S., Wallace D.C., Huang T. Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production. PLoS One 2009, 4:e4492.
    • (2009) PLoS One , vol.4
    • Tang, S.1    Le, P.K.2    Tse, S.3    Wallace, D.C.4    Huang, T.5
  • 106
    • 5444236916 scopus 로고    scopus 로고
    • Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1
    • Varadi A., Johnson-Cadwell L.I., Cirulli V., Yoon Y., Allan V.J., Rutter G.A. Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1. J. Cell Sci. 2004, 117:4389-4400.
    • (2004) J. Cell Sci. , vol.117 , pp. 4389-4400
    • Varadi, A.1    Johnson-Cadwell, L.I.2    Cirulli, V.3    Yoon, Y.4    Allan, V.J.5    Rutter, G.A.6
  • 107
    • 23044506102 scopus 로고    scopus 로고
    • Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions
    • Verstreken P., Ly C.V., Venken K.J., Koh T.W., Zhou Y., Bellen H.J. Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron 2005, 47:365-378.
    • (2005) Neuron , vol.47 , pp. 365-378
    • Verstreken, P.1    Ly, C.V.2    Venken, K.J.3    Koh, T.W.4    Zhou, Y.5    Bellen, H.J.6
  • 109
    • 67650732998 scopus 로고    scopus 로고
    • Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
    • Wang X., Su B., Lee H.G., Li X., Perry G., Smith M.A., Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J. Neurosci. 2009, 29:9090-9103.
    • (2009) J. Neurosci. , vol.29 , pp. 9090-9103
    • Wang, X.1    Su, B.2    Lee, H.G.3    Li, X.4    Perry, G.5    Smith, M.A.6    Zhu, X.7
  • 112
    • 0025990093 scopus 로고
    • The beginning of pattern formation in the Drosophila compound eye: the morphogenetic furrow and the second mitotic wave
    • Wolff T., Ready D.F. The beginning of pattern formation in the Drosophila compound eye: the morphogenetic furrow and the second mitotic wave. Development 1991, 113:841-850.
    • (1991) Development , vol.113 , pp. 841-850
    • Wolff, T.1    Ready, D.F.2
  • 113
    • 33746080412 scopus 로고    scopus 로고
    • Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
    • Yang Y., Gehrke S., Imai Y., Huang Z., Ouyang Y., Wang J.W., Yang L., Beal M.F., Vogel H., Lu B. Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:10793-10798.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 10793-10798
    • Yang, Y.1    Gehrke, S.2    Imai, Y.3    Huang, Z.4    Ouyang, Y.5    Wang, J.W.6    Yang, L.7    Beal, M.F.8    Vogel, H.9    Lu, B.10
  • 116
    • 0032559599 scopus 로고    scopus 로고
    • A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells
    • Yoon Y., Pitts K.R., Dahan S., McNiven M.A. A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells. J. Cell Biol. 1998, 140:779-793.
    • (1998) J. Cell Biol. , vol.140 , pp. 779-793
    • Yoon, Y.1    Pitts, K.R.2    Dahan, S.3    McNiven, M.A.4
  • 118
    • 0037128923 scopus 로고    scopus 로고
    • The role of ARK in stress-induced apoptosis in Drosophila cells
    • Zimmermann K.C., Ricci J.E., Droin N.M., Green D.R. The role of ARK in stress-induced apoptosis in Drosophila cells. J. Cell Biol. 2002, 156:1077-1087.
    • (2002) J. Cell Biol. , vol.156 , pp. 1077-1087
    • Zimmermann, K.C.1    Ricci, J.E.2    Droin, N.M.3    Green, D.R.4
  • 119
    • 77950384477 scopus 로고    scopus 로고
    • Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
    • Ziviani E., Tao R.N., Whitworth A.J. Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:5018-5023.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 5018-5023
    • Ziviani, E.1    Tao, R.N.2    Whitworth, A.J.3


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