-
1
-
-
33750705653
-
A century of Alzheimer's disease
-
Goedert M, Spillantini MG (2006) A century of Alzheimer's disease. Science 314: 777-781.
-
(2006)
Science
, vol.314
, pp. 777-781
-
-
Goedert, M.1
Spillantini, M.G.2
-
2
-
-
38349092352
-
Calcium dysregulation in Alzheimer's disease
-
Bojarski L, Herms J, Kuznicki J (2008) Calcium dysregulation in Alzheimer's disease. Neurochem Int 52:621-633.
-
(2008)
Neurochem Int
, vol.52
, pp. 621-633
-
-
Bojarski, L.1
Herms, J.2
Kuznicki, J.3
-
3
-
-
77953634580
-
ER calcium and Alzheimer's disease: In a state of flux
-
Mattson MP (2010) ER calcium and Alzheimer's disease: In a state of flux. Sci Signal 3: pe10.
-
(2010)
Sci Signal
, vol.3
-
-
Mattson, M.P.1
-
4
-
-
79952607633
-
2+ dysregulation mediated by presenilins in familial Alzheimer's disease: Causing or modulating factor?
-
2+ dysregulation mediated by presenilins in familial Alzheimer's disease: Causing or modulating factor? Curr Trends Neurol 3:1-14.
-
(2009)
Curr Trends Neurol
, vol.3
, pp. 1-14
-
-
Zampese, E.1
Brunello, L.2
Fasolato, C.3
Pizzo, P.4
-
5
-
-
46249123354
-
SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production
-
DOI 10.1083/jcb.200706171
-
Green KN, et al. (2008) SERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production. J Cell Biol 181:1107-1116. (Pubitemid 351915486)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.7
, pp. 1107-1116
-
-
Green, K.N.1
Demuro, A.2
Akbari, Y.3
Hitt, B.D.4
Smith, I.F.5
Parker, I.6
LaFerla, F.M.7
-
6
-
-
77449105037
-
2+ uptake
-
2+ uptake. J Cell Mol Med 13(9B):3358-3369.
-
(2009)
J Cell Mol Med
, vol.13
, Issue.9 B
, pp. 3358-3369
-
-
Brunello, L.1
-
7
-
-
33748140720
-
2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations
-
DOI 10.1016/j.cell.2006.06.059, PII S0092867406010257
-
Tu H, et al. (2006) Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 126:981-993. (Pubitemid 44310781)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 981-993
-
-
Tu, H.1
Nelson, O.2
Bezprozvanny, A.3
Wang, Z.4
Lee, S.-F.5
Hao, Y.-H.6
Serneels, L.7
De Strooper, B.8
Yu, G.9
Bezprozvanny, I.10
-
8
-
-
34248185927
-
2+ leak function of presenilin 1
-
2+ leak function of presenilin 1. J Clin Invest 117:1230-1239.
-
(2007)
J Clin Invest
, vol.117
, pp. 1230-1239
-
-
Nelson, O.1
-
9
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla FM (2002) Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat Rev Neurosci 3:862-872.
-
(2002)
Nat Rev Neurosci
, vol.3
, pp. 862-872
-
-
LaFerla, F.M.1
-
10
-
-
33750441184
-
Presenilins and Alzheimer disease: The calcium conspiracy
-
DOI 10.1038/nn1106-1354, PII NN11061354
-
Thinakaran G, Sisodia SS (2006) Presenilins and Alzheimer disease: The calcium conspiracy. Nat Neurosci 9:1354-1355. (Pubitemid 44646201)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.11
, pp. 1354-1355
-
-
Thinakaran, G.1
Sisodia, S.S.2
-
11
-
-
45249117227
-
2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating
-
2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. Neuron 58:871-883.
-
(2008)
Neuron
, vol.58
, pp. 871-883
-
-
Cheung, K.H.1
-
12
-
-
77953644150
-
Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons
-
Cheung KH, et al. (2010) Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons. Sci Signal 3:ra22.
-
(2010)
Sci Signal
, vol.3
-
-
Cheung, K.H.1
-
13
-
-
47749095383
-
Linking Calcium to Abeta and Alzheimer's Disease
-
DOI 10.1016/j.neuron.2008.07.013, PII S0896627308005862
-
Green KN, LaFerla FM (2008) Linking calcium to Abeta and Alzheimer's disease. Neuron 59:190-194. (Pubitemid 352033693)
-
(2008)
Neuron
, vol.59
, Issue.2
, pp. 190-194
-
-
Green, K.N.1
LaFerla, F.M.2
-
14
-
-
73649098791
-
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria
-
Area-Gomez E, et al. (2009) Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol 175:1810-1816.
-
(2009)
Am J Pathol
, vol.175
, pp. 1810-1816
-
-
Area-Gomez, E.1
-
16
-
-
65449139544
-
Mitochondria, calcium and cell death: A deadly triad in neurodegeneration
-
Celsi F, et al. (2009) Mitochondria, calcium and cell death: A deadly triad in neurodegeneration. Biochim Biophys Acta 1787:335-344.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 335-344
-
-
Celsi, F.1
-
17
-
-
71849083948
-
Abnormal mitochondrial dynamics and neurodegenerative diseases
-
Su B, et al. (2010) Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta 1802:135-142.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 135-142
-
-
Su, B.1
-
18
-
-
77956224679
-
The Alzheimer's disease mitochondrial cascade hypothesis
-
Swerdlow RH, Burns JM, Khan SM (2010) The Alzheimer's disease mitochondrial cascade hypothesis. J Alzheimers Dis 20(Suppl 2):S265-S279.
-
(2010)
J Alzheimers Dis
, vol.20
, Issue.SUPPL. 2
-
-
Swerdlow, R.H.1
Burns, J.M.2
Khan, S.M.3
-
19
-
-
77956026971
-
Alzheimer's disease: Diverse aspects of mitochondrial malfunctioning
-
Santos RX, et al. (2010) Alzheimer's disease: Diverse aspects of mitochondrial malfunctioning. Int J Clin Exp Pathol 3:570-581.
-
(2010)
Int J Clin Exp Pathol
, vol.3
, pp. 570-581
-
-
Santos, R.X.1
-
20
-
-
33646377385
-
Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels
-
Zatti G, et al. (2006) Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels. Cell Calcium 39:539-550.
-
(2006)
Cell Calcium
, vol.39
, pp. 539-550
-
-
Zatti, G.1
-
23
-
-
33644847375
-
2+: Molecular determinants and functional consequences
-
2+: Molecular determinants and functional consequences. Physiol Rev 86:369-408.
-
(2006)
Physiol Rev
, vol.86
, pp. 369-408
-
-
Rizzuto, R.1
Pozzan, T.2
-
24
-
-
0027418205
-
Measurement of co-localization of objects in dual-colour confocal images
-
Manders EMM, Verbeek FJ, Aten JA (1993) Measurement of co-localization of object in dual-colour confocal images. J Microsc 169:375-382. (Pubitemid 23119681)
-
(1993)
Journal of Microscopy
, vol.169
, Issue.3
, pp. 375-382
-
-
Manders, E.M.M.1
Verbeek, F.J.2
Aten, J.A.3
-
25
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
de Brito OM, Scorrano L (2008) Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456:605-610.
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
De Brito, O.M.1
Scorrano, L.2
-
26
-
-
0032511112
-
2+ responses
-
2+ responses. Science 280:1763-1766.
-
(1998)
Science
, vol.280
, pp. 1763-1766
-
-
Rizzuto, R.1
-
27
-
-
53749105377
-
Presenilins: Members of the gamma-secretase quartets, but part-time soloists too
-
Wakabayashi T, De Strooper B (2008) Presenilins: Members of the gamma-secretase quartets, but part-time soloists too. Physiology (Bethesda) 23:194-204.
-
(2008)
Physiology (Bethesda)
, vol.23
, pp. 194-204
-
-
Wakabayashi, T.1
De Strooper, B.2
-
28
-
-
13244299288
-
Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios
-
DOI 10.1111/j.1471-4159.2004.02858.x
-
Walker ES, Martinez M, Brunkan AL, Goate A (2005) Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios. J Neurochem 92:294-301. (Pubitemid 40194020)
-
(2005)
Journal of Neurochemistry
, vol.92
, Issue.2
, pp. 294-301
-
-
Walker, E.S.1
Martinez, M.2
Brunkan, A.L.3
Goate, A.4
-
29
-
-
33748553081
-
Differential role of presenilin-1 and -2 on mitochondrial membrane potential and oxygen consumption in mouse embryonic fibroblasts
-
DOI 10.1002/jnr.20990
-
Behbahani H, et al. (2006) Differential role of Presenilin-1 and -2 on mitochondrial membrane potential and oxygen consumption in mouse embryonic fibroblasts. J Neurosci Res 84:891-902. (Pubitemid 44366690)
-
(2006)
Journal of Neuroscience Research
, vol.84
, Issue.4
, pp. 891-902
-
-
Behbahani, H.1
Shabalina, I.G.2
Wiehager, B.3
Concha, H.4
Hultenby, K.5
Petrovic, N.6
Nedergaard, J.7
Winblad, B.8
Cowburn, R.F.9
Ankarcrona, M.10
-
30
-
-
77955041880
-
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria
-
Cárdenas C, et al. (2010) Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell 142:270-283.
-
(2010)
Cell
, vol.142
, pp. 270-283
-
-
Cárdenas, C.1
-
32
-
-
0037418843
-
2+: A control point for apoptosis
-
2+: A control point for apoptosis. Science 300:135-139.
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
|