A Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Kennedy, Michael A ^a   Moffat, Tia C ^a   Gable, Kenneth ^b   Ganesan, Suriakarthiga ^c   Niewola Staszkowska, Karolina ^d   Johnston, Anne ^e   Nislow, Corey ^f   Giaever, Guri ^f   Harris, Linda J ^e   Loewith, Robbie ^d   Zaremberg, Vanina ^c   Harper, Mary Ellen ^a   Dunn, Teresa ^b   Bennett, Steffany A L ^a   Baetz, Kristin ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b Uniformed Services University of the Health Sciences   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e OTTAWA RESEARCH AND DEVELOPMENT CENTRE   (Canada)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CERAMIDE; MULTIPROTEIN COMPLEX; REACTIVE OXYGEN METABOLITE; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ALZHEIMER DISEASE; CELL CULTURE; CELL LINE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; LIPID METABOLISM; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NERVE CELL; OPEN READING FRAME; OXIDATIVE STRESS; PATHOLOGY; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; CELL LINE; CELLS, CULTURED; CERAMIDES; GENE EXPRESSION PROFILING; HUMANS; LIPID METABOLISM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MULTIPROTEIN COMPLEXES; NEURONS; OPEN READING FRAMES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84954164606     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep19332     Document Type: Article

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