Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS

Neuron

Volumn 67, Issue 4, 2010, Pages 575-587

  Israelson, Adrian ^a   Arbel, Nir ^b   Da Cruz, Sandrine ^a   Ilieva, Hristelina ^a   Yamanaka, Koji ^c   Shoshan Barmatz, Varda ^b   Cleveland, Don W ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United States)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Cellbio; Humdisease; Molneuro

Indexed keywords

ADENOSINE DIPHOSPHATE; COPPER ZINC SUPEROXIDE DISMUTASE; VOLTAGE DEPENDENT ANION CHANNEL 1; CALCIUM; LIPID BILAYER; SUPEROXIDE DISMUTASE; VDAC1 PROTEIN, MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; GENE MUTATION; GENE TARGETING; IN VITRO STUDY; LIPID BILAYER; MEMBRANE CONDUCTANCE; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION; RAT; SPINAL CORD; ANIMAL; CHEMISTRY; DISEASE MODEL; ELECTRIC CONDUCTIVITY; GENETICS; HUMAN; METABOLISM; MISSENSE MUTATION; MITOCHONDRION; MORTALITY; PARALYSIS; TRANSGENIC MOUSE; TRANSGENIC RAT;

ADENOSINE DIPHOSPHATE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CALCIUM; DISEASE MODELS, ANIMAL; ELECTRIC CONDUCTIVITY; HUMANS; LIPID BILAYERS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MUTATION, MISSENSE; PARALYSIS; PROTEIN FOLDING; RATS; RATS, TRANSGENIC; SPINAL CORD; SUPEROXIDE DISMUTASE; VOLTAGE-DEPENDENT ANION CHANNEL 1;

EID: 77955961922     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2010.07.019     Document Type: Article

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